KEGG   PATHWAY: dme04070
Entry
dme04070                    Pathway                                
Name
Phosphatidylinositol signaling system - Drosophila melanogaster (fruit fly)
Class
Environmental Information Processing; Signal transduction
Pathway map
dme04070  Phosphatidylinositol signaling system
dme04070

Organism
Drosophila melanogaster (fruit fly) [GN:dme]
Gene
Dmel_CG10082  Ip6k; inositol hexakisphosphate kinase, isoform B [KO:K07756] [EC:2.7.4.21]
Dmel_CG10260  Pi4KIIIalpha; phosphatidylinositol 4-kinase III alpha, isoform D [KO:K00888] [EC:2.7.1.67]
Dmel_CG10426  INPP5E; inositol polyphosphate 5-phosphatase E, isoform B [KO:K20278] [EC:3.1.3.36]
Dmel_CG1063  Itpr; inositol 1,4,5,-trisphosphate receptor, isoform B [KO:K04958]
Dmel_CG11165  azot; ahuizotl [KO:K02183]
Dmel_CG11621  Pi3K68D; phosphatidylinositol 3-kinase 68D, isoform D [KO:K00923] [EC:2.7.1.154]
Dmel_CG13526  CG13526; uncharacterized protein [KO:K02183]
Dmel_CG13688  Ipk2; inositol phosphate kinase 2 [KO:K00915] [EC:2.7.1.140 2.7.1.151]
Dmel_CG13898  CG13898; uncharacterized protein [KO:K02183]
Dmel_CG14616  l(1)G0196; lethal (1) G0196, isoform I [KO:K13024] [EC:2.7.4.24]
Dmel_CG15743  CG15743; uncharacterized protein, isoform B [KO:K15759] [EC:3.1.3.7]
Dmel_CG15855  Eip63F-1; Ecdysone-induced protein 63F 1, isoform A [KO:K02183]
Dmel_CG17026  CG17026; uncharacterized protein [KO:K01092] [EC:3.1.3.25]
Dmel_CG17027  CG17027; uncharacterized protein, isoform B [KO:K01092] [EC:3.1.3.25]
Dmel_CG17028  CG17028; uncharacterized protein, isoform B [KO:K01092] [EC:3.1.3.25]
Dmel_CG17029  CG17029; uncharacterized protein, isoform B [KO:K01092] [EC:3.1.3.25]
Dmel_CG17471  PIP4K; phosphatidylinositol 5-phosphate 4-kinase, isoform B [KO:K00889] [EC:2.7.1.68]
Dmel_CG17769  Acam; androcam, isoform B [KO:K02183]
Dmel_CG17770  CG17770; uncharacterized protein [KO:K02183]
Dmel_CG2699  Pi3K21B; Pi3K21B, isoform C [KO:K02649]
Dmel_CG2929  Pi4KIIalpha; phosphatidylinositol 4-kinase II alpha, isoform E [KO:K13711] [EC:2.7.1.67]
Dmel_CG3028  Ipp; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
Dmel_CG30295  Ipk1; inositol phosphate kinase 1, isoform A [KO:K10572] [EC:2.7.1.158]
Dmel_CG30378  CG30378; uncharacterized protein [KO:K02183]
Dmel_CG31140  CG31140; uncharacterized protein, isoform D [KO:K00901] [EC:2.7.1.107]
Dmel_CG31960  CG31960; uncharacterized protein [KO:K02183]
Dmel_CG34361  Dgk; diacyl glycerol kinase, isoform E [KO:K00901] [EC:2.7.1.107]
Dmel_CG34384  CG34384; uncharacterized protein, isoform A [KO:K00901] [EC:2.7.1.107]
Dmel_CG3530  Mtmr6; myotubularin related protein 6, isoform C [KO:K18083] [EC:3.1.3.64 3.1.3.95]
Dmel_CG3573  Ocrl; oculocerebrorenal syndrome of lowe, isoform B [KO:K01099] [EC:3.1.3.36]
Dmel_CG3620  norpA; no receptor potential A, isoform D [KO:K05858] [EC:3.1.4.11]
Dmel_CG3632  CG3632; uncharacterized protein, isoform E [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
Dmel_CG3682  PIP5K59B; phosphatidylinositol 4-phosphate 5-kinase 59B, isoform I [KO:K00889] [EC:2.7.1.68]
Dmel_CG4026  IP3K1; inositol 1,4,5-triphosphate kinase 1, isoform B [KO:K00911] [EC:2.7.1.127]
Dmel_CG4141  Pi3K92E; phosphatidylinositol 3-kinase 92E, isoform C [KO:K00922] [EC:2.7.1.153]
Dmel_CG4200  sl; small wing [KO:K01116] [EC:3.1.4.11]
Dmel_CG42271  CG42271; uncharacterized protein, isoform C [KO:K01109] [EC:3.1.3.66]
Dmel_CG42283  5PtaseI; inositol polyphosphate-5-phosphatase type I, isoform C [KO:K01106] [EC:3.1.3.56]
Dmel_CG42667  rdgA; retinal degeneration A, isoform A [KO:K00901] [EC:2.7.1.107]
Dmel_CG45017  IP3K2; inositol 1,4,5-triphosphate kinase 2, isoform C [KO:K00911] [EC:2.7.1.127]
Dmel_CG4574  Plc21C; phospholipase C at 21C, isoform D [KO:K05858] [EC:3.1.4.11]
Dmel_CG5024  CG5024; uncharacterized protein, isoform B [KO:K02183]
Dmel_CG5373  Pi3K59F; phosphatidylinositol 3-kinase 59F [KO:K00914] [EC:2.7.1.137]
Dmel_CG5671  Pten; phosphatase and tensin homolog, isoform G [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Dmel_CG6355  fab1; fab1 kinase, isoform A [KO:K00921] [EC:2.7.1.150]
Dmel_CG6518  inaC; inactivation no afterpotential C [KO:K02677] [EC:2.7.11.13]
Dmel_CG6542  EDTP; Egg-derived tyrosine phosphatase, isoform A [KO:K18086] [EC:3.1.3.64 3.1.3.95]
Dmel_CG6562  Synj; synaptojanin, isoform C [KO:K20279] [EC:3.1.3.36]
Dmel_CG6622  Pkc53E; protein C kinase 53E, isoform B [KO:K02677] [EC:2.7.11.13]
Dmel_CG6707  CG6707; uncharacterized protein, isoform A [KO:K13084] [EC:3.1.3.78]
Dmel_CG7004  fwd; four wheel drive, isoform D [KO:K19801] [EC:2.7.1.67]
Dmel_CG7956  sp3; spermathreecae, isoform G [KO:K21798] [EC:3.1.3.-]
Dmel_CG7962  Cds; CDP-diacylglycerol synthase, isoform B [KO:K00981] [EC:2.7.7.41]
Dmel_CG8472  Cam; calmodulin, isoform C [KO:K02183]
Dmel_CG8657  Dgkepsilon; diacyl glycerol kinase epsilon, isoform B [KO:K00901] [EC:2.7.1.107]
Dmel_CG9115  mtm; myotubularin, isoform B [KO:K18081] [EC:3.1.3.64 3.1.3.95]
Dmel_CG9128  Sac1; Sac1 phosphatase, isoform B [KO:K21797] [EC:3.1.3.-]
Dmel_CG9245  Pis; phosphatidylinositol synthase, isoform A [KO:K00999] [EC:2.7.8.11]
Dmel_CG9389  CG9389; uncharacterized protein [KO:K01092] [EC:3.1.3.25]
Dmel_CG9391  CG9391; uncharacterized protein, isoform A [KO:K01092] [EC:3.1.3.25]
Dmel_CG9985  sktl; skittles, isoform B [KO:K00889] [EC:2.7.1.68]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
dme04144  Endocytosis
KO pathway
ko04070   

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