KEGG   PATHWAY: dre00562
Entry
dre00562                    Pathway                                
Name
Inositol phosphate metabolism - Danio rerio (zebrafish)
Class
Metabolism; Carbohydrate metabolism
Pathway map
dre00562  Inositol phosphate metabolism
dre00562

Module
dre_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:dre00562]
dre_M00131  Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:dre00562]
dre_M00132  Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:dre00562]
Other DBs
GO: 0006020
Organism
Danio rerio (zebrafish) [GN:dre]
Gene
100000275  [KO:K01771] [EC:4.6.1.13]
100000352  [KO:K01771] [EC:4.6.1.13]
100001532  plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
100002263  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
100002310  [KO:K01771] [EC:4.6.1.13]
100005033  pip5k1cb; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma B [KO:K00889] [EC:2.7.1.68]
100006223  si:dkey-266f7.9; uncharacterized protein isoform X1 [KO:K01771] [EC:4.6.1.13]
100037338  inpp5ka; inositol polyphosphate 5-phosphatase Ka [KO:K24222]
100148744  itpk1b; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
100149843  pip5kl1; phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform X1 [KO:K13712] [EC:2.7.1.68]
100151036  ipmka; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
100317089  inpp5jb; inositol polyphosphate 5-phosphatase K [KO:K24222]
100330514  pik3c2g; phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X5 [KO:K00923] [EC:2.7.1.154]
100333801  [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
100334231  plch2a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2a isoform X1 [KO:K19006] [EC:3.1.4.11]
100334605  fig4a; polyphosphoinositide phosphatase isoform X1 [KO:K22913] [EC:3.1.3.-]
100535634  pip4k2cb; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1 [KO:K00920] [EC:2.7.1.149]
100537538  plcb4a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
101884438  inpp5a; inositol polyphosphate-5-phosphatase A [KO:K01106] [EC:3.1.3.56]
192309  tpi1a; triosephosphate isomerase A [KO:K01803] [EC:5.3.1.1]
30644  mtmr2; phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
322041  ip6k2a; inositol hexakisphosphate kinase 2a [KO:K07756] [EC:2.7.4.21]
322720  itpkcb; inositol-trisphosphate 3-kinase Cb [KO:K00911] [EC:2.7.1.127]
323929  mtmr14; phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
325179  inppl1a; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A [KO:K15909] [EC:3.1.3.86]
327346  mtmr6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
337236  synj1; synaptojanin-1 [KO:K20279] [EC:3.1.3.36]
337489  plcd1b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1b [KO:K05857] [EC:3.1.4.11]
337690  [KO:K00921] [EC:2.7.1.150]
368415  ptenb; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 2 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
368433  inppl1b; inositol polyphosphate phosphatase-like 1b [KO:K15909] [EC:3.1.3.86]
368717  itpka; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
373124  pip4k2ca; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
373867  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
393365  mtmr8; phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
393584  mtmr4; phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4 isoform X2 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
393838  mtmr3; myotubularin-related protein 3 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
394075  minpp1b; multiple inositol polyphosphate phosphatase 1b precursor [KO:K03103] [EC:3.1.3.62 3.1.3.80]
394174  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
404620  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
406290  itpk1a; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
406598  pik3cg; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
406667  pi4k2a; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
407700  plcb4b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
436647  aldh6a1; methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial [KO:K00140] [EC:1.2.1.18 1.2.1.27]
436662  ip6k2b; inositol hexakisphosphate kinase 2b [KO:K07756] [EC:2.7.4.21]
437018  impa1; inositol monophosphatase 1 isoform X1 [KO:K01092] [EC:3.1.3.25]
447840  pip5k1bb; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
449831  pip5k1ba; phosphatidylinositol-4-phosphate 5-kinase, type I, beta a isoform X2 [KO:K00889] [EC:2.7.1.68]
449862  ppip5k2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X4 [KO:K13024] [EC:2.7.4.24]
492549  pip5k1ab; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha [KO:K00889] [EC:2.7.1.68]
541511  ippK; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
541517  mtmr1b; myotubularin-related protein 1B [KO:K18081] [EC:3.1.3.64 3.1.3.95]
548346  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
553595  impa2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
553629  pip5k1aa; phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, A [KO:K00889] [EC:2.7.1.68]
553750  mtmr1a; myotubularin-related protein 1A [KO:K18081] [EC:3.1.3.64 3.1.3.95]
555443  plcd1a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1a [KO:K05857] [EC:3.1.4.11]
555899  [KO:K01107] [EC:3.1.3.57]
555920  pip4k2ab; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
556748  ppip5k1a; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X5 [KO:K13024] [EC:2.7.4.24]
556956  pi4kaa; phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
558940  sacm1la; phosphatidylinositol-3-phosphatase SAC1-A [KO:K21797] [EC:3.1.3.-]
559103  inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1 [KO:K03084] [EC:3.1.3.86]
559198  mtmr7b; myotubularin-related protein 7B [KO:K18083] [EC:3.1.3.64 3.1.3.95]
559938  ppip5k1b; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
560006  inpp4b; inositol polyphosphate 4-phosphatase type II isoform X8 [KO:K01109] [EC:3.1.3.66]
560360  pip4k2aa; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [KO:K00920] [EC:2.7.1.149]
560753  tpi1b; triosephosphate isomerase B [KO:K01803] [EC:5.3.1.1]
560881  mtm1; myotubularin isoform 1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
560919  plch2b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 isoform X1 [KO:K19006] [EC:3.1.4.11]
561475  plcd4b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
561737  pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
561747  plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
561891  minpp1a; multiple inositol polyphosphate phosphatase 1a [KO:K03103] [EC:3.1.3.62 3.1.3.80]
562569  plcd3b; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A-like isoform X1 [KO:K05857] [EC:3.1.4.11]
563201  pi4kb; phosphatidylinositol 4-kinase beta [KO:K19801] [EC:2.7.1.67]
563543  inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
564261  si:rp71-17i16.5; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
564478  ip6k1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
564750  pi4k2b; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
565669  plcd4a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1 [KO:K05857] [EC:3.1.4.11]
566188  inpp5kb; inositol polyphosphate 5-phosphatase K isoform X1 [KO:K24222]
566479  plch1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X1 [KO:K19006] [EC:3.1.4.11]
567938  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
568288  plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
569040  plcd3a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A [KO:K05857] [EC:3.1.4.11]
569376  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
569568  inpp5ja; inositol polyphosphate 5-phosphatase K [KO:K24222]
570007  inpp5f; phosphatidylinositide phosphatase SAC2 [KO:K21798] [EC:3.1.3.-]
571356  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
571850  mioX; inositol oxygenase [KO:K00469] [EC:1.13.99.1]
606579  inpp5e; phosphatidylinositol polyphosphate 5-phosphatase type IV isoform X2 [KO:K20278] [EC:3.1.3.36]
641571  inpp5l; inositol polyphosphate-5-phosphatase A [KO:K01106] [EC:3.1.3.56]
664741  inpp4aa; inositol polyphosphate-4-phosphatase type I A [KO:K01109] [EC:3.1.3.66]
678558  mtmr7a; myotubularin-related protein 7A [KO:K18083] [EC:3.1.3.64 3.1.3.95]
777716  ocrL; inositol polyphosphate 5-phosphatase OCRL [KO:K01099] [EC:3.1.3.36]
790916  ipmkb; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
791141  zgc:158659; uncharacterized protein isoform X1 [KO:K00922] [EC:2.7.1.153]
791142  sacm1lb; phosphatidylinositol-3-phosphatase SAC1-B [KO:K21797] [EC:3.1.3.-]
792527  inpp4ab; inositol polyphosphate-4-phosphatase type I Ab [KO:K01109] [EC:3.1.3.66]
794088  ptena; phosphatase and tensin homolog A [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
798876  pip5k1ca; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X2 [KO:K00889] [EC:2.7.1.68]
Compound
C00024  Acetyl-CoA
C00092  D-Glucose 6-phosphate
C00111  Glycerone phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00137  myo-Inositol
C00191  D-Glucuronate
C00222  3-Oxopropanoate
C00558  D-Tagaturonate
C00641  1,2-Diacyl-sn-glycerol
C00691  2,4,6/3,5-Pentahydroxycyclohexanone
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C03659  D-Bornesitol
C03660  L-Bornesitol
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04287  3D-3,5/4-Trihydroxycyclohexane-1,2-dione
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04520  1D-myo-Inositol 3,4,5,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04563  D-myo-Inositol 1,2,4,5,6-pentakisphosphate
C04579  Inositol 1,2,3,5,6-pentakisphosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C06153  scyllo-Inositol
C06892  2-Deoxy-5-keto-D-gluconic acid
C06893  2-Deoxy-5-keto-D-gluconic acid 6-phosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C16737  5-Deoxy-D-glucuronate
C19794  CDP-1L-myo-inositol
C19799  Bis(1L-myo-inositol)-3,1'-phosphate 1-phosphate
C19891  1D-chiro-Inositol
C20251  1-Keto-D-chiro-inositol
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
C21643  3-Dehydro-scyllo-inosose
C21644  5-Dehydro-L-gluconate
Reference
PMID:14993306
  Authors
Yoshida K, Yamaguchi M, Ikeda H, Omae K, Tsurusaki K, Fujita Y
  Title
The fifth gene of the iol operon of Bacillus subtilis, iolE, encodes 2-keto-myo-inositol dehydratase.
  Journal
Microbiology 150:571-80 (2004)
DOI:10.1099/mic.0.26768-0
Reference
PMID:18310071
  Authors
Yoshida K, Yamaguchi M, Morinaga T, Kinehara M, Ikeuchi M, Ashida H, Fujita Y.
  Title
myo-Inositol catabolism in Bacillus subtilis.
  Journal
J Biol Chem 283:10415-24 (2008)
DOI:10.1074/jbc.M708043200
Related
pathway
dre00010  Glycolysis / Gluconeogenesis
dre00020  Citrate cycle (TCA cycle)
dre00040  Pentose and glucuronate interconversions
dre00564  Glycerophospholipid metabolism
KO pathway
ko00562   

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