KEGG   PATHWAY: lmut04070
Entry
lmut04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Lagopus muta (rock ptarmigan)
Class
Environmental Information Processing; Signal transduction
Pathway map
lmut04070  Phosphatidylinositol signaling system
lmut04070

Organism
Lagopus muta (rock ptarmigan) [GN:lmut]
Gene
125684035  IP6K3; inositol hexakisphosphate kinase 3 [KO:K07756] [EC:2.7.4.21]
125684198  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [KO:K00923] [EC:2.7.1.154]
125684288  ITPR3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1 [KO:K04960]
125684417  PIP4K2B; phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
125684552  PLCD3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X1 [KO:K05857] [EC:3.1.4.11]
125684928  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
125685084  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta [KO:K02649]
125685213  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
125685415  INPP1; LOW QUALITY PROTEIN: inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
125685550  DGKA; LOW QUALITY PROTEIN: diacylglycerol kinase alpha [KO:K00901] [EC:2.7.1.107]
125685742  PI4KB; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
125685809  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
125686542  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
125686658  DGKI; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
125686983  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
125687152  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
125687195  DGKQ; LOW QUALITY PROTEIN: diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
125687281  PPIP5K2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
125687519  DGKH; LOW QUALITY PROTEIN: diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
125687638  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
125688029  ITPR2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1 [KO:K04959]
125688102  MTMR6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
125688231  [KO:K02183]
125688277  SYNJ1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
125688743  SYNJ2; synaptojanin-2 isoform X1 [KO:K20279] [EC:3.1.3.36]
125689139  CALM2; calmodulin-2 [KO:K02183]
125689525  [KO:K00911] [EC:2.7.1.127]
125689751  MTMR2; myotubularin-related protein 2 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
125690171  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
125690172  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
125690415  IMPA1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
125690472  [KO:K01116] [EC:3.1.4.11]
125690615  IMPA2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
125690873  PIP4P2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
125691041  BPNT2; Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase [KO:K15759] [EC:3.1.3.7]
125691581  INPP4B; inositol polyphosphate 4-phosphatase type II isoform X1 [KO:K01109] [EC:3.1.3.66]
125691987  PI4K2B; phosphatidylinositol 4-kinase type 2-beta isoform X1 [KO:K13711] [EC:2.7.1.67]
125692194  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
125692638  MTMR7; myotubularin-related protein 7 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
125692833  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
125692874  INPP5A; inositol polyphosphate-5-phosphatase A isoform X1 [KO:K01106] [EC:3.1.3.56]
125692898  INPP5F; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
125693311  IPMK; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
125693728  PI4K2A; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
125694122  PIK3R3; phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
125694243  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
125694452  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
125694485  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1 [KO:K00923] [EC:2.7.1.154]
125694588  DGKZ; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
125694720  CALM1; calmodulin-1 [KO:K02183]
125695496  ITPKA; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
125695594  ITPK1; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
125695728  PIP4K2A; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
125695743  DGKB; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
125695970  SACM1L; phosphatidylinositol-3-phosphatase SAC1 [KO:K21797] [EC:3.1.3.-]
125696260  PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [KO:K05857] [EC:3.1.4.11]
125696758  PIKFYVE; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
125697172  PLCD4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1 [KO:K05857] [EC:3.1.4.11]
125697457  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
125697618  INPP5D; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1 [KO:K03084] [EC:3.1.3.86]
125697629  PIK3C2G; phosphatidylinositol 3-kinase C2 domain-containing subunit gamma isoform X1 [KO:K00923] [EC:2.7.1.154]
125697659  [KO:K00901] [EC:2.7.1.107]
125697863  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
125697869  DGKD; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
125697993  PPIP5K1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
125698103  CALML4; calmodulin-like protein 4 isoform X1 [KO:K02183]
125698537  IP6K1; inositol hexakisphosphate kinase 1 isoform X1 [KO:K07756] [EC:2.7.4.21]
125698595  MTMR14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
125698750  IP6K2; inositol hexakisphosphate kinase 2 [KO:K07756] [EC:2.7.4.21]
125698895  ITPR1; inositol 1,4,5-trisphosphate receptor type 1 [KO:K04958]
125698989  IPPK; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
125699039  PLCG2; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
125699315  PLCZ1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [KO:K05861] [EC:3.1.4.11]
125699610  OCRL; inositol polyphosphate 5-phosphatase OCRL isoform X1 [KO:K01099] [EC:3.1.3.36]
125699711  MTMR8; myotubularin-related protein 8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
125699809  [KO:K15909] [EC:3.1.3.86]
125699820  [KO:K00901] [EC:2.7.1.107]
125699897  MTMR1; myotubularin-related protein 1 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
125699898  MTM1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
125700557  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
125700576  INPP4A; inositol polyphosphate-4-phosphatase type I A isoform X1 [KO:K01109] [EC:3.1.3.66]
125701080  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
125701524  MTMR3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
125701527  PI4KA; phosphatidylinositol 4-kinase alpha isoform X1 [KO:K00888] [EC:2.7.1.67]
125702087  DGKE; diacylglycerol kinase epsilon isoform X1 [KO:K00901] [EC:2.7.1.107]
125702349  PRKCA; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
125702465  INPP5E; phosphatidylinositol polyphosphate 5-phosphatase type IV [KO:K20278] [EC:3.1.3.36]
125702722  INPPL1; LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 [KO:K15909] [EC:3.1.3.86]
125703070  MTMR4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
125703469  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
125703837  INPP5B; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
lmut04020  Calcium signaling pathway
lmut04144  Endocytosis
lmut04510  Focal adhesion
KO pathway
ko04070   

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