KEGG   PATHWAY: mlf00670
Entry
mlf00670                    Pathway                                
Name
One carbon pool by folate - Myotis lucifugus (little brown bat)
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
mlf00670  One carbon pool by folate
mlf00670

Module
mlf_M00035  Methionine degradation [PATH:mlf00670]
mlf_M00141  C1-unit interconversion, eukaryotes [PATH:mlf00670]
mlf_M00338  Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:mlf00670]
mlf_M00555  Betaine biosynthesis, choline => betaine [PATH:mlf00670]
mlf_M00621  Glycine cleavage system [PATH:mlf00670]
mlf_M00974  Betaine metabolism, animals, betaine => glycine [PATH:mlf00670]
Other DBs
GO: 0035999
Organism
Myotis lucifugus (little brown bat) [GN:mlf]
Gene
102418273  [KO:K01758] [EC:4.4.1.1]
102418312  FTCD; formimidoyltransferase-cyclodeaminase [KO:K13990] [EC:2.1.2.5 4.3.1.4]
102418889  SHMT2; serine hydroxymethyltransferase, mitochondrial [KO:K00600] [EC:2.1.2.1]
102421206  DHFR; dihydrofolate reductase [KO:K00287] [EC:1.5.1.3]
102422643  GLDC; glycine dehydrogenase (decarboxylating), mitochondrial [KO:K00281] [EC:1.4.4.2]
102423324  MAT1A; S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
102423671  AMT; aminomethyltransferase, mitochondrial [KO:K00605] [EC:2.1.2.10]
102424075  AHCYL2; LOW QUALITY PROTEIN: adenosylhomocysteinase 3 [KO:K01251] [EC:3.13.2.1]
102424778  GART; trifunctional purine biosynthetic protein adenosine-3 isoform X1 [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
102425902  BHMT; betaine--homocysteine S-methyltransferase 1 [KO:K00544] [EC:2.1.1.5]
102426434  DMGDH; dimethylglycine dehydrogenase, mitochondrial [KO:K00315] [EC:1.5.8.4]
102426627  MTHFD2; bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [KO:K13403] [EC:1.5.1.15 3.5.4.9]
102426926  MTHFD2L; probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [KO:K13403] [EC:1.5.1.15 3.5.4.9]
102426955  BHMT2; S-methylmethionine--homocysteine S-methyltransferase BHMT2 [KO:K00547] [EC:2.1.1.10]
102427323  AHCY; LOW QUALITY PROTEIN: adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
102427801  MTHFD1; LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic [KO:K00288] [EC:1.5.1.5 3.5.4.9 6.3.4.3]
102428410  MAT2B; methionine adenosyltransferase 2 subunit beta isoform X1 [KO:K00789] [EC:2.5.1.6]
102428800  AHCYL1; LOW QUALITY PROTEIN: S-adenosylhomocysteine hydrolase-like protein 1 [KO:K01251] [EC:3.13.2.1]
102429354  [KO:K13402] [EC:6.3.4.3]
102429979  MAT2A; S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
102431108  MTR; methionine synthase isoform X1 [KO:K00548] [EC:2.1.1.13]
102431813  [KO:K01758] [EC:4.4.1.1]
102432547  CHDH; choline dehydrogenase, mitochondrial isoform X1 [KO:K00108] [EC:1.1.99.1]
102433635  CBS; LOW QUALITY PROTEIN: cystathionine beta-synthase [KO:K01697] [EC:4.2.1.22]
102433777  ALDH1L2; mitochondrial 10-formyltetrahydrofolate dehydrogenase isoform X1 [KO:K00289] [EC:1.5.1.6]
102435890  ALDH1L1; cytosolic 10-formyltetrahydrofolate dehydrogenase [KO:K00289] [EC:1.5.1.6]
102435920  GCSH; glycine cleavage system H protein, mitochondrial [KO:K02437]
102437960  MTHFR; LOW QUALITY PROTEIN: methylenetetrahydrofolate reductase [KO:K25004]
102438609  DLD; dihydrolipoyl dehydrogenase, mitochondrial isoform X1 [KO:K00382] [EC:1.8.1.4]
102439913  ATIC; bifunctional purine biosynthesis protein PURH isoform X1 [KO:K00602] [EC:2.1.2.3 3.5.4.10]
102441362  TYMS; thymidylate synthase [KO:K00560] [EC:2.1.1.45]
102441477  SHMT1; serine hydroxymethyltransferase, cytosolic isoform X2 [KO:K00600] [EC:2.1.2.1]
102441975  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase isoform X1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
102442398  GNMT; glycine N-methyltransferase [KO:K00552] [EC:2.1.1.20]
102442988  [KO:K00789] [EC:2.5.1.6]
Compound
C00002  ATP
C00019  S-Adenosyl-L-methionine
C00021  S-Adenosyl-L-homocysteine
C00037  Glycine
C00065  L-Serine
C00073  L-Methionine
C00097  L-Cysteine
C00101  Tetrahydrofolate
C00114  Choline
C00143  5,10-Methylenetetrahydrofolate
C00155  L-Homocysteine
C00212  Adenosine
C00213  Sarcosine
C00234  10-Formyltetrahydrofolate
C00364  dTMP
C00365  dUMP
C00415  Dihydrofolate
C00440  5-Methyltetrahydrofolate
C00445  5,10-Methenyltetrahydrofolate
C00504  Folate
C00576  Betaine aldehyde
C00664  5-Formiminotetrahydrofolate
C00719  Betaine
C01026  N,N-Dimethylglycine
C02291  L-Cystathionine
C03479  Folinic acid
Related
pathway
mlf00260  Glycine, serine and threonine metabolism
mlf00270  Cysteine and methionine metabolism
mlf00790  Folate biosynthesis
KO pathway
ko00670   

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