KEGG   PATHWAY: nni03083
Entry
nni03083                    Pathway                                
Name
Polycomb repressive complex - Nipponia nippon (crested ibis)
Class
Genetic Information Processing; Chromosome
Pathway map
nni03083  Polycomb repressive complex
nni03083

Organism
Nipponia nippon (crested ibis) [GN:nni]
Gene
104008583  HDAC2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
104008707  SFMBT1; scm-like with four MBT domains protein 1 [KO:K26269]
104008733  BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [KO:K08588] [EC:3.4.19.12]
104008842  L3MBTL3; lethal(3)malignant brain tumor-like protein 3 [KO:K24387]
104009386  KDM2A; lysine-specific demethylase 2A [KO:K10276] [EC:1.14.11.27]
104009771  MBD5; methyl-CpG-binding domain protein 5 [KO:K23219]
104009878  EZH1; histone-lysine N-methyltransferase EZH1 [KO:K17451] [EC:2.1.1.356]
104009952  DCAF7; DDB1- and CUL4-associated factor 7 [KO:K11805]
104010122  [KO:K11488]
104010495  SFMBT2; scm-like with four MBT domains protein 2 [KO:K26269]
104011310  RNF2; E3 ubiquitin-protein ligase RING2 [KO:K10695] [EC:2.3.2.27]
104011884  PCGF2; polycomb group RING finger protein 2 [KO:K11460]
104012003  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
104012448  AUTS2; autism susceptibility gene 2 protein [KO:K23214]
104012700  LCOR; ligand-dependent corepressor [KO:K26260]
104012908  OGT; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1 [KO:K09667] [EC:2.4.1.255]
104013016  E2F6; transcription factor E2F6 [KO:K09390]
104013056  PCGF5; polycomb group RING finger protein 5 isoform X1 [KO:K11489]
104013513  UBE2D1; ubiquitin-conjugating enzyme E2 D1 isoform X1 [KO:K06689] [EC:2.3.2.23]
104013632  YAF2; YY1-associated factor 2 [KO:K11468]
104013927  CBX3; chromobox protein homolog 3 isoform X1 [KO:K11586]
104014270  CBX2; chromobox protein homolog 2 [KO:K11451]
104014271  CBX8; chromobox protein homolog 8 [KO:K11455]
104014310  SUZ12; polycomb protein SUZ12 [KO:K11463]
104014326  CBX4; E3 SUMO-protein ligase CBX4 [KO:K11452] [EC:2.3.2.-]
104014581  PHC1; polyhomeotic-like protein 1 [KO:K11456]
104014784  ASXL2; LOW QUALITY PROTEIN: putative Polycomb group protein ASXL2 [KO:K11471]
104014836  YY1; transcriptional repressor protein YY1 [KO:K09201]
104015220  FOXK1; forkhead box protein K1 [KO:K09404]
104015388  EZH2; histone-lysine N-methyltransferase EZH2 isoform X1 [KO:K11430] [EC:2.1.1.356]
104015494  MTF2; LOW QUALITY PROTEIN: metal-response element-binding transcription factor 2 [KO:K11485]
104015637  SCMH1; polycomb protein SCMH1 [KO:K11461]
104016218  [KO:K11459]
104016932  RYBP; RING1 and YY1-binding protein [KO:K11469]
104017392  EED; polycomb protein EED [KO:K11462]
104017556  PCGF3; polycomb group RING finger protein 3 [KO:K11488]
104017757  RBBP4; histone-binding protein RBBP4 [KO:K10752]
104017768  HDAC1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
104017817  [KO:K24387]
104017954  AEBP2; zinc finger protein AEBP2 [KO:K17452]
104018173  TEX10; testis-expressed sequence 10 protein isoform X1 [KO:K14827]
104018312  ASXL1; putative Polycomb group protein ASXL1 [KO:K11471]
104019179  MBD6; methyl-CpG-binding domain protein 6 [KO:K26585]
104019364  TFDP1; transcription factor Dp-1 isoform X1 [KO:K04683]
104019494  KDM2B; lysine-specific demethylase 2B [KO:K10276] [EC:1.14.11.27]
104019775  ASXL3; putative Polycomb group protein ASXL3 [KO:K11471]
104019936  FBRSL1; fibrosin-1-like protein [KO:K26254]
104019949  L3MBTL1; lethal(3)malignant brain tumor-like protein 1 [KO:K24387]
104020086  BCOR; LOW QUALITY PROTEIN: BCL-6 corepressor [KO:K23215]
104020108  USP16; ubiquitin carboxyl-terminal hydrolase 16 isoform X1 [KO:K11844] [EC:3.4.19.12]
104020352  MGA; MAX gene-associated protein [KO:K23399]
104020565  [KO:K04453]
104021182  UBE2D3; ubiquitin-conjugating enzyme E2 D3 isoform X1 [KO:K06689] [EC:2.3.2.23]
104021538  [KO:K04453]
104021618  CBX7; chromobox protein homolog 7 [KO:K11454]
104021637  EP300; LOW QUALITY PROTEIN: histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
104021700  L3MBTL2; lethal(3)malignant brain tumor-like protein 2 [KO:K24387]
104021807  JARID2; LOW QUALITY PROTEIN: protein Jumonji [KO:K11478]
104021930  USP45; ubiquitin carboxyl-terminal hydrolase 45 [KO:K11844] [EC:3.4.19.12]
104022049  PHC3; polyhomeotic-like protein 3 [KO:K11458]
104022141  [KO:K06689] [EC:2.3.2.23]
104022363  PCGF6; polycomb group RING finger protein 6 [KO:K11470]
104022522  SCML2; sex comb on midleg-like protein 2 [KO:K11465]
104022523  RBBP7; histone-binding protein RBBP7 [KO:K11659]
104022886  FOXK2; forkhead box protein K2 [KO:K09404]
104022968  BCORL1; BCL-6 corepressor-like protein 1 [KO:K26199]
104023199  WDR5; WD repeat-containing protein 5 [KO:K14963]
104023214  PHF19; PHD finger protein 19 [KO:K11486]
104023443  USP7; ubiquitin carboxyl-terminal hydrolase 7 [KO:K11838] [EC:3.4.19.12]
104023464  CREBBP; CREB-binding protein [KO:K04498] [EC:2.3.1.48]
Reference
PMID:21881606
  Authors
Richly H, Aloia L, Di Croce L
  Title
Roles of the Polycomb group proteins in stem cells and cancer.
  Journal
Cell Death Dis 2:e204 (2011)
DOI:10.1038/cddis.2011.84
Reference
PMID:28202673
  Authors
Chittock EC, Latwiel S, Miller TC, Muller CW
  Title
Molecular architecture of polycomb repressive complexes.
  Journal
Biochem Soc Trans 45:193-205 (2017)
DOI:10.1042/BST20160173
Reference
PMID:33202645
  Authors
Geng Z, Gao Z
  Title
Mammalian PRC1 Complexes: Compositional Complexity and Diverse Molecular Mechanisms.
  Journal
Int J Mol Sci 21:ijms21228594 (2020)
DOI:10.3390/ijms21228594
Reference
PMID:35681061
  Authors
Kim JJ, Kingston RE
  Title
Context-specific Polycomb mechanisms in development.
  Journal
Nat Rev Genet 23:680-695 (2022)
DOI:10.1038/s41576-022-00499-0
Reference
PMID:36076977
  Authors
Dong GJ, Xu JL, Qi YR, Yuan ZQ, Zhao W
  Title
Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer.
  Journal
Int J Mol Sci 23:ijms23179574 (2022)
DOI:10.3390/ijms23179574
Reference
PMID:37086328
  Authors
Ryan CW, Peirent ER, Regan SL, Guxholli A, Bielas SL
  Title
H2A monoubiquitination: insights from human genetics and animal models.
  Journal
Hum Genet 10.1007/s00439-023-02557-x (2023)
DOI:10.1007/s00439-023-02557-x
KO pathway
ko03083   

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