KEGG   PATHWAY: aaa00230
Entry
aaa00230                    Pathway                                
Name
Purine metabolism - Paracidovorax avenae
Class
Metabolism; Nucleotide metabolism
Pathway map
aaa00230  Purine metabolism
aaa00230

Module
aaa_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:aaa00230]
aaa_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:aaa00230]
aaa_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:aaa00230]
aaa_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:aaa00230]
aaa_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:aaa00230]
aaa_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:aaa00230]
aaa_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:aaa00230]
Other DBs
GO: 0006163 0042278
Organism
Paracidovorax avenae [GN:aaa]
Gene
Acav_3525  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Acav_1802  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Acav_2056  Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Acav_3305  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Acav_2529  formyl transferase domain protein [KO:K11175] [EC:2.1.2.2]
Acav_4159  phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
Acav_2184  Phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
Acav_3193  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Acav_4483  phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
Acav_4482  phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
Acav_4479  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Acav_4605  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Acav_3133  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Acav_0845  phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Acav_4779  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Acav_3881  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
Acav_3920  5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
Acav_1453  stationary-phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Acav_1796  protein of unknown function DUF1255 [KO:K09913] [EC:2.4.2.1 2.4.2.2]
Acav_2737  Multi-copper polyphenol oxidoreductase, laccase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Acav_1868  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Acav_1459  Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Acav_3489  non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
Acav_1131  xanthine dehydrogenase, small subunit [KO:K13481] [EC:1.17.1.4]
Acav_1130  xanthine dehydrogenase, molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
Acav_3911  Xanthine dehydrogenase [KO:K11177] [EC:1.17.1.4]
Acav_1524  Xanthine dehydrogenase [KO:K11177] [EC:1.17.1.4]
Acav_3912  Xanthine dehydrogenase [KO:K11178] [EC:1.17.1.4]
Acav_1525  Xanthine dehydrogenase [KO:K11178] [EC:1.17.1.4]
Acav_3913  (2Fe-2S)-binding domain-containing protein [KO:K13483]
Acav_1526  (2Fe-2S)-binding domain-containing protein [KO:K13483]
Acav_0393  glutamine amidotransferase class-I [KO:K01951] [EC:6.3.5.2]
Acav_1871  GMP synthase, large subunit [KO:K01951] [EC:6.3.5.2]
Acav_3255  guanosine monophosphate reductase [KO:K00364] [EC:1.7.1.7]
Acav_1153  guanine deaminase [KO:K01487] [EC:3.5.4.3]
Acav_3494  guanylate kinase [KO:K00942] [EC:2.7.4.8]
Acav_0796  ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
Acav_0636  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
Acav_0795  Ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
Acav_0975  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Acav_2480  metal dependent phosphohydrolase [KO:K06952] [EC:3.1.3.89]
Acav_3496  (p)ppGpp synthetase I, SpoT/RelA [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Acav_2578  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Acav_1635  (p)ppGpp synthetase I, SpoT/RelA [KO:K00951] [EC:2.7.6.5]
Acav_2723  RelA/SpoT domain protein [KO:K07816] [EC:2.7.6.5]
Acav_4566  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Acav_2203  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Acav_3378  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
Acav_1473  Adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
Acav_0793  Adenosine kinase [KO:K00856] [EC:2.7.1.20]
Acav_4136  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
Acav_1148  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
Acav_3723  2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
Acav_2647  adenylate kinase [KO:K00939] [EC:2.7.4.3]
Acav_3328  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
Acav_1159  bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [KO:K01525] [EC:3.6.1.41]
Acav_4666  adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
Acav_2226  sulfate adenylyltransferase, large subunit [KO:K00956] [EC:2.7.7.4]
Acav_2227  Sulfate adenylyltransferase [KO:K00957] [EC:2.7.7.4]
Acav_4408  FAD-dependent pyridine nucleotide-disulfide oxidoreductase [KO:K22879] [EC:1.14.13.113]
Acav_1113  hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
Acav_1081  Hydantoin racemase [KO:K16841] [EC:5.1.99.3]
Acav_1599  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
Acav_1108  urate catabolism protein [KO:K16842] [EC:3.5.2.5]
Acav_0259  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
Acav_1666  Ureidoglycolate lyase [KO:K16856] [EC:4.3.2.3]
Acav_3424  urease, alpha subunit [KO:K01428] [EC:3.5.1.5]
Acav_3423  urease, beta subunit [KO:K01429] [EC:3.5.1.5]
Acav_3421  urease, gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
aaa00030  Pentose phosphate pathway
aaa00220  Arginine biosynthesis
aaa00250  Alanine, aspartate and glutamate metabolism
aaa00260  Glycine, serine and threonine metabolism
aaa00340  Histidine metabolism
aaa00630  Glyoxylate and dicarboxylate metabolism
aaa00730  Thiamine metabolism
aaa00740  Riboflavin metabolism
aaa00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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