KEGG   PATHWAY: bkw00230
Entry
bkw00230                    Pathway                                
Name
Purine metabolism - Halalkalibacter krulwichiae
Class
Metabolism; Nucleotide metabolism
Pathway map
bkw00230  Purine metabolism
bkw00230

Module
bkw_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bkw00230]
bkw_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bkw00230]
bkw_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bkw00230]
bkw_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bkw00230]
bkw_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bkw00230]
Other DBs
GO: 0006163 0042278
Organism
Halalkalibacter krulwichiae [GN:bkw]
Gene
BkAM31D_06240  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
BkAM31D_03960  deoB_1; Phosphopentomutase [KO:K01839] [EC:5.4.2.7]
BkAM31D_06270  deoB_2; Phosphopentomutase [KO:K01839] [EC:5.4.2.7]
BkAM31D_04265  pgcA; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
BkAM31D_00325  prs; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
BkAM31D_01940  purF; Amidophosphoribosyltransferase precursor [KO:K00764] [EC:2.4.2.14]
BkAM31D_01960  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
BkAM31D_01950  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
BkAM31D_01935  purL; Phosphoribosylformylglycinamidine synthase 2 [KO:K23269] [EC:6.3.5.3]
BkAM31D_01925  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
BkAM31D_01930  purQ; Phosphoribosylformylglycinamidine synthase 1 [KO:K23265] [EC:6.3.5.3 3.5.1.2]
BkAM31D_01945  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
BkAM31D_01910  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
BkAM31D_01905  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
BkAM31D_01920  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
BkAM31D_01915  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
BkAM31D_01955  purH; Bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
BkAM31D_04750  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
BkAM31D_21690  yhcR; Endonuclease YhcR precursor [KO:K01081] [EC:3.1.3.5]
BkAM31D_20140  yfkN; Trifunctional nucleotide phosphoesterase protein YfkN precursor [KO:K01081] [EC:3.1.3.5]
BkAM31D_03965  punA_1; Purine nucleoside phosphorylase 1 [KO:K03783] [EC:2.4.2.1]
BkAM31D_06275  punA_2; Purine nucleoside phosphorylase 1 [KO:K03783] [EC:2.4.2.1]
BkAM31D_15805  deoD; Purine nucleoside phosphorylase DeoD-type [KO:K03784] [EC:2.4.2.1]
BkAM31D_15190  Laccase domain protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
BkAM31D_00435  hpt; Hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
BkAM31D_00065  guaB_1; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
BkAM31D_10985  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
BkAM31D_19025  yjjX; Non-canonical purine NTP phosphatase [KO:K01529] [EC:3.6.1.73]
BkAM31D_18330  Non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
BkAM31D_06150  xpt; Xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
BkAM31D_03135  pucD; putative xanthine dehydrogenase subunit D [KO:K00087] [EC:1.17.1.4]
BkAM31D_03130  pucC; putative xanthine dehydrogenase subunit C [KO:K13479] [EC:1.17.1.4]
BkAM31D_01845  guaA; GMP synthase, glutamine-hydrolyzing [KO:K01951] [EC:6.3.5.2]
BkAM31D_07040  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
BkAM31D_15045  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
BkAM31D_02025  nrdE2; Ribonucleoside-diphosphate reductase subunit alpha 2 [KO:K00525] [EC:1.17.4.1]
BkAM31D_16995  nrdZ; Ribonucleoside-diphosphate reductase NrdZ [KO:K00525] [EC:1.17.4.1]
BkAM31D_02030  nrdB; Ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
BkAM31D_19290  dgk; Deoxyguanosine kinase [KO:K15518] [EC:2.7.1.113]
BkAM31D_04755  relA; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
BkAM31D_05530  ppx; Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
BkAM31D_17290  yjbM; GTP pyrophosphokinase YjbM [KO:K07816] [EC:2.7.6.5]
BkAM31D_12060  ywaC; GTP pyrophosphokinase YwaC [KO:K07816] [EC:2.7.6.5]
BkAM31D_25250  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
BkAM31D_19295  dck; Deoxyadenosine/deoxycytidine kinase [KO:K15519] [EC:2.7.1.76 2.7.1.74]
BkAM31D_23055  Adenine deaminase [KO:K01488] [EC:3.5.4.4]
BkAM31D_01975  yerA; Putative adenine deaminase YerA [KO:K01486] [EC:3.5.4.2]
BkAM31D_01990  adeC_1; Adenine deaminase [KO:K01486] [EC:3.5.4.2]
BkAM31D_21560  adeC_2; Adenine deaminase [KO:K01486] [EC:3.5.4.2]
BkAM31D_14380  hypothetical protein [KO:K09769] [EC:3.1.4.16]
BkAM31D_00830  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
BkAM31D_06005  cysC; putative adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
BkAM31D_05995  sat; Sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
BkAM31D_24995  Ferredoxin--NADP reductase [KO:K22879] [EC:1.14.13.113]
BkAM31D_03165  pucM; 5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
BkAM31D_03160  pucL; Uric acid degradation bifunctional protein PucL [KO:K13485] [EC:4.1.1.97]
BkAM31D_12385  allB; Allantoinase [KO:K01466] [EC:3.5.2.5]
BkAM31D_03175  amaB; N-carbamoyl-L-amino acid hydrolase [KO:K02083] [EC:3.5.3.9]
BkAM31D_03180  pucG; Purine catabolism protein PucG [KO:K00839] [EC:2.6.1.112]
BkAM31D_24560  ureC; Urease subunit alpha [KO:K01428] [EC:3.5.1.5]
BkAM31D_24555  ureB; Urease subunit beta [KO:K01429] [EC:3.5.1.5]
BkAM31D_24550  ureA; Urease subunit gamma [KO:K01430] [EC:3.5.1.5]
BkAM31D_03225  ywrD_1; Putative gamma-glutamyltransferase YwrD [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bkw00030  Pentose phosphate pathway
bkw00220  Arginine biosynthesis
bkw00250  Alanine, aspartate and glutamate metabolism
bkw00260  Glycine, serine and threonine metabolism
bkw00340  Histidine metabolism
bkw00630  Glyoxylate and dicarboxylate metabolism
bkw00730  Thiamine metabolism
bkw00740  Riboflavin metabolism
bkw00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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