KEGG   PATHWAY: brp00270
Entry
brp00270                    Pathway                                
Name
Cysteine and methionine metabolism - Brassica rapa (field mustard)
Description
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].
Class
Metabolism; Amino acid metabolism
Pathway map
brp00270  Cysteine and methionine metabolism
brp00270

Module
brp_M00021  Cysteine biosynthesis, serine => cysteine [PATH:brp00270]
brp_M00034  Methionine salvage pathway [PATH:brp00270]
brp_M00368  Ethylene biosynthesis, methionine => ethylene [PATH:brp00270]
Other DBs
GO: 0006534 0006555
Organism
Brassica rapa (field mustard) [GN:brp]
Gene
103870196  serine acetyltransferase 3, mitochondrial [KO:K00640] [EC:2.3.1.30]
103845106  serine acetyltransferase 5 [KO:K00640] [EC:2.3.1.30]
103832545  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
103874110  serine acetyltransferase 2 [KO:K00640] [EC:2.3.1.30]
103871006  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
103856800  serine acetyltransferase 5 [KO:K00640] [EC:2.3.1.30]
103868374  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
103849160  bifunctional L-3-cyanoalanine synthase/cysteine synthase D1 isoform X1 [KO:K01738] [EC:2.5.1.47]
103871539  cysteine synthase [KO:K01738] [EC:2.5.1.47]
103854642  bifunctional L-3-cyanoalanine synthase/cysteine synthase D2 [KO:K01738] [EC:2.5.1.47]
103837317  bifunctional cystathionine gamma-lyase/cysteine synthase isoform X2 [KO:K01738] [EC:2.5.1.47]
103837318  bifunctional L-3-cyanoalanine synthase/cysteine synthase D2 [KO:K01738] [EC:2.5.1.47]
103833476  OASA4; cysteine synthase [KO:K01738] [EC:2.5.1.47]
103871013  cysteine synthase 2 [KO:K01738] [EC:2.5.1.47]
103866104  cysteine synthase, chloroplastic/chromoplastic [KO:K01738] [EC:2.5.1.47]
103859070  bifunctional L-3-cyanoalanine synthase/cysteine synthase D1 [KO:K01738] [EC:2.5.1.47]
103862931  cysteine synthase, mitochondrial [KO:K01738] [EC:2.5.1.47]
103866743  cysteine synthase, chloroplastic/chromoplastic [KO:K01738] [EC:2.5.1.47]
103841966  bifunctional L-3-cyanoalanine synthase/cysteine synthase C1, mitochondrial [KO:K13034] [EC:2.5.1.47 4.4.1.9]
103862824  bifunctional L-3-cyanoalanine synthase/cysteine synthase C1, mitochondrial isoform X1 [KO:K13034] [EC:2.5.1.47 4.4.1.9]
103841611  cystathionine beta-lyase, chloroplastic isoform X2 [KO:K01760] [EC:4.4.1.13]
103863064  cystathionine beta-lyase, chloroplastic [KO:K01760] [EC:4.4.1.13]
103861272  cystine lyase CORI3 [KO:K21623] [EC:4.4.1.35]
103875335  homocysteine S-methyltransferase 1 [KO:K00547] [EC:2.1.1.10]
103842126  selenocysteine Se-methyltransferase-like [KO:K00547] [EC:2.1.1.10]
103869013  homocysteine S-methyltransferase 3 [KO:K00547] [EC:2.1.1.10]
103862723  selenocysteine Se-methyltransferase [KO:K00547] [EC:2.1.1.10]
103845623  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 3, chloroplastic isoform X1 [KO:K00549] [EC:2.1.1.14]
103845887  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1 [KO:K00549] [EC:2.1.1.14]
103851137  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1 [KO:K00549] [EC:2.1.1.14]
103856274  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1 [KO:K00549] [EC:2.1.1.14]
103856476  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 3, chloroplastic [KO:K00549] [EC:2.1.1.14]
103859011  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 2 [KO:K00549] [EC:2.1.1.14]
103849483  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
103839308  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
103836799  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
103865564  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
103858801  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
103857642  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
103859706  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
103867247  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
103841158  S-adenosylmethionine decarboxylase proenzyme 1-like [KO:K01611] [EC:4.1.1.50]
103843101  S-adenosylmethionine decarboxylase proenzyme 3 [KO:K01611] [EC:4.1.1.50]
103845798  S-adenosylmethionine decarboxylase proenzyme 4 [KO:K01611] [EC:4.1.1.50]
103851201  S-adenosylmethionine decarboxylase proenzyme 4 [KO:K01611] [EC:4.1.1.50]
103846371  S-adenosylmethionine decarboxylase proenzyme 2 [KO:K01611] [EC:4.1.1.50]
103858959  S-adenosylmethionine decarboxylase proenzyme 3 [KO:K01611] [EC:4.1.1.50]
103856350  S-adenosylmethionine decarboxylase proenzyme 4 [KO:K01611] [EC:4.1.1.50]
103856870  S-adenosylmethionine decarboxylase proenzyme 2 [KO:K01611] [EC:4.1.1.50]
103844792  spermine synthase isoform X1 [KO:K00797] [EC:2.5.1.16]
103829257  spermidine synthase 1 [KO:K00797] [EC:2.5.1.16]
103835646  spermidine synthase 1 [KO:K00797] [EC:2.5.1.16]
103852054  spermine synthase [KO:K00797] [EC:2.5.1.16]
103840733  spermidine synthase 1 [KO:K00797] [EC:2.5.1.16]
103867728  nicotianamine synthase 1-like [KO:K05953] [EC:2.5.1.43]
103847645  probable nicotianamine synthase 4 [KO:K05953] [EC:2.5.1.43]
103871652  nicotianamine synthase 3 [KO:K05953] [EC:2.5.1.43]
103866247  nicotianamine synthase 1 [KO:K05953] [EC:2.5.1.43]
103845041  nicotianamine synthase 2-like [KO:K05953] [EC:2.5.1.43]
103851850  nicotianamine synthase 2 [KO:K05953] [EC:2.5.1.43]
103855599  nicotianamine synthase 1 [KO:K05953] [EC:2.5.1.43]
103847238  LOW QUALITY PROTEIN: nicotianamine synthase 1 [KO:K05953] [EC:2.5.1.43]
103835162  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1 [KO:K01244] [EC:3.2.2.16]
103834385  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2 isoform X2 [KO:K01244] [EC:3.2.2.16]
103871404  methylthioribose kinase [KO:K00899] [EC:2.7.1.100]
103828510  methylthioribose-1-phosphate isomerase [KO:K08963] [EC:5.3.1.23]
103844853  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 isoform X1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
103852010  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
103871834  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
103848836  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 4 isoform X2 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
103839226  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 4 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
103830559  probable N-succinyldiaminopimelate aminotransferase DapC [KO:K23977] [EC:2.6.1.117]
103854450  probable aminotransferase TAT1 [KO:K00815] [EC:2.6.1.5]
103842591  tyrosine aminotransferase [KO:K00815] [EC:2.6.1.5]
103842224  probable aminotransferase TAT3 isoform X1 [KO:K00815] [EC:2.6.1.5]
103868301  tyrosine aminotransferase [KO:K00815] [EC:2.6.1.5]
103861413  cystine lyase CORI3-like [KO:K00815] [EC:2.6.1.5]
103852000  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
103861830  S-alkyl-thiohydroximate lyase SUR1 [KO:K00815] [EC:2.6.1.5]
103858362  probable aminotransferase TAT3 [KO:K00815] [EC:2.6.1.5]
103830431  aromatic aminotransferase ISS1 [KO:K00837] [EC:2.6.1.-]
103853264  aromatic aminotransferase ISS1 isoform X2 [KO:K00837] [EC:2.6.1.-]
103832493  aromatic aminotransferase ISS1 isoform X2 [KO:K00837] [EC:2.6.1.-]
103838186  methionine gamma-lyase [KO:K01761] [EC:4.4.1.11]
103857074  DNA (cytosine-5)-methyltransferase CMT2 isoform X1 [KO:K00558] [EC:2.1.1.37]
103864404  DNA (cytosine-5)-methyltransferase 1 [KO:K00558] [EC:2.1.1.37]
103873920  DNA (cytosine-5)-methyltransferase CMT3 [KO:K00558] [EC:2.1.1.37]
103871899  putative DNA (cytosine-5)-methyltransferase CMT1 [KO:K00558] [EC:2.1.1.37]
103874835  LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 1-like [KO:K00558] [EC:2.1.1.37]
103842448  DNA (cytosine-5)-methyltransferase 1 [KO:K00558] [EC:2.1.1.37]
103837173  uncharacterized protein LOC103837173 [KO:K17398] [EC:2.1.1.37]
103832114  adenosylhomocysteinase 2 [KO:K01251] [EC:3.13.2.1]
103833147  adenosylhomocysteinase 1 [KO:K01251] [EC:3.13.2.1]
103828704  adenosylhomocysteinase 2 [KO:K01251] [EC:3.13.2.1]
103860008  adenosylhomocysteinase 2 [KO:K01251] [EC:3.13.2.1]
103863580  adenosylhomocysteinase 1 [KO:K01251] [EC:3.13.2.1]
103833884  1-aminocyclopropane-1-carboxylate synthase 6 [KO:K20772] [EC:4.4.1.14]
103844651  1-aminocyclopropane-1-carboxylate synthase 2 [KO:K20772] [EC:4.4.1.14]
103841975  1-aminocyclopropane-1-carboxylate synthase-like protein 1 [KO:K20772] [EC:4.4.1.14]
103864396  1-aminocyclopropane-1-carboxylate synthase 4 [KO:K01762] [EC:4.4.1.14]
103855315  1-aminocyclopropane-1-carboxylate synthase 5 [KO:K01762] [EC:4.4.1.14]
103865940  1-aminocyclopropane-1-carboxylate synthase 7 [KO:K01762] [EC:4.4.1.14]
103857842  1-aminocyclopropane-1-carboxylate synthase 8 [KO:K01762] [EC:4.4.1.14]
103860626  1-aminocyclopropane-1-carboxylate synthase 9 [KO:K01762] [EC:4.4.1.14]
103858466  1-aminocyclopropane-1-carboxylate synthase 11 [KO:K01762] [EC:4.4.1.14]
103861616  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
103873033  1-aminocyclopropane-1-carboxylate synthase 9-like [KO:K01762] [EC:4.4.1.14]
103874018  1-aminocyclopropane-1-carboxylate synthase 5 [KO:K01762] [EC:4.4.1.14]
103835047  1-aminocyclopropane-1-carboxylate synthase 8 [KO:K01762] [EC:4.4.1.14]
103837595  1-aminocyclopropane-1-carboxylate synthase 5 [KO:K01762] [EC:4.4.1.14]
103848186  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
103830571  1-aminocyclopropane-1-carboxylate oxidase 5 [KO:K05933] [EC:1.14.17.4]
103828296  1-aminocyclopropane-1-carboxylate oxidase 1 [KO:K05933] [EC:1.14.17.4]
103838399  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
103843208  1-aminocyclopropane-1-carboxylate oxidase 3 [KO:K05933] [EC:1.14.17.4]
103842633  1-aminocyclopropane-1-carboxylate oxidase 1 [KO:K05933] [EC:1.14.17.4]
103853067  1-aminocyclopropane-1-carboxylate oxidase 5 [KO:K05933] [EC:1.14.17.4]
103832184  LOW QUALITY PROTEIN: 1-aminocyclopropane-1-carboxylate oxidase 5 [KO:K05933] [EC:1.14.17.4]
103872037  1-aminocyclopropane-1-carboxylate oxidase 3 [KO:K05933] [EC:1.14.17.4]
103844184  1-aminocyclopropane-1-carboxylate oxidase 4 [KO:K05933] [EC:1.14.17.4]
117126758  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
103846584  aspartokinase 1, chloroplastic [KO:K00928] [EC:2.7.2.4]
103851914  aspartokinase 3, chloroplastic [KO:K00928] [EC:2.7.2.4]
103856056  aspartokinase 2, chloroplastic isoform X2 [KO:K00928] [EC:2.7.2.4]
103850857  aspartokinase 1, chloroplastic [KO:K00928] [EC:2.7.2.4]
103857732  bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic [KO:K12524] [EC:2.7.2.4 1.1.1.3]
103840260  bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic [KO:K12524] [EC:2.7.2.4 1.1.1.3]
103836051  aspartate-semialdehyde dehydrogenase [KO:K00133] [EC:1.2.1.11]
103872275  aspartate-semialdehyde dehydrogenase [KO:K00133] [EC:1.2.1.11]
103845967  homoserine kinase [KO:K00872] [EC:2.7.1.39]
103837797  homoserine kinase [KO:K00872] [EC:2.7.1.39]
103874187  homoserine kinase [KO:K00872] [EC:2.7.1.39]
103870949  cystathionine gamma-synthase 1, chloroplastic [KO:K27857] [EC:2.5.1.160]
103847532  cystathionine gamma-synthase 1, chloroplastic [KO:K27857] [EC:2.5.1.160]
103858929  cystathionine gamma-synthase 1, chloroplastic [KO:K27857] [EC:2.5.1.160]
103868123  branched-chain-amino-acid aminotransferase 1, mitochondrial isoform X1 [KO:K00826] [EC:2.6.1.42]
103868121  branched-chain-amino-acid aminotransferase 2, chloroplastic [KO:K00826] [EC:2.6.1.42]
103875438  branched-chain-amino-acid aminotransferase 3, chloroplastic [KO:K00826] [EC:2.6.1.42]
103871785  branched-chain-amino-acid aminotransferase 1, mitochondrial isoform X1 [KO:K00826] [EC:2.6.1.42]
103871787  branched-chain-amino-acid aminotransferase 2, chloroplastic [KO:K00826] [EC:2.6.1.42]
103873035  branched-chain-amino-acid aminotransferase 3, chloroplastic [KO:K00826] [EC:2.6.1.42]
103832897  LOW QUALITY PROTEIN: branched-chain-amino-acid aminotransferase 6 [KO:K00826] [EC:2.6.1.42]
103832898  putative branched-chain-amino-acid aminotransferase 7 [KO:K00826] [EC:2.6.1.42]
103871365  branched-chain-amino-acid aminotransferase 6 [KO:K00826] [EC:2.6.1.42]
103843316  branched-chain-amino-acid aminotransferase 2, chloroplastic-like isoform X1 [KO:K00826] [EC:2.6.1.42]
103851253  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
103835108  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial isoform X1 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
103865668  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
103857781  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
103859327  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial isoform X2 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
103867109  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial isoform X1 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
103860794  glutamate--cysteine ligase, chloroplastic [KO:K01919] [EC:6.3.2.2]
103861360  glutamate--cysteine ligase, chloroplastic [KO:K01919] [EC:6.3.2.2]
103861359  glutamate--cysteine ligase, chloroplastic-like isoform X1 [KO:K01919] [EC:6.3.2.2]
103837332  glutathione synthetase, chloroplastic isoform X1 [KO:K21456] [EC:6.3.2.3]
103874543  glutathione synthetase, chloroplastic [KO:K21456] [EC:6.3.2.3]
103848200  aspartate aminotransferase, cytoplasmic isozyme 2 [KO:K14454] [EC:2.6.1.1]
103851283  aspartate aminotransferase, cytoplasmic isozyme 1 [KO:K14454] [EC:2.6.1.1]
103845742  aspartate aminotransferase, cytoplasmic isozyme 1 [KO:K14454] [EC:2.6.1.1]
103838043  aspartate aminotransferase, cytoplasmic isozyme 2 isoform X1 [KO:K14454] [EC:2.6.1.1]
103838363  aspartate aminotransferase, cytoplasmic isozyme 2 [KO:K14454] [EC:2.6.1.1]
103855915  aspartate aminotransferase 3, chloroplastic [KO:K14454] [EC:2.6.1.1]
103865090  aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
103851376  aspartate aminotransferase, chloroplastic [KO:K00811] [EC:2.6.1.1]
103862102  aspartate aminotransferase, chloroplastic [KO:K00811] [EC:2.6.1.1]
103830493  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
103832400  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial [KO:K01011] [EC:2.8.1.1 2.8.1.2]
103872432  thiosulfate/3-mercaptopyruvate sulfurtransferase 2 isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
103868260  L-lactate dehydrogenase B [KO:K00016] [EC:1.1.1.27]
103860904  L-lactate dehydrogenase B [KO:K00016] [EC:1.1.1.27]
103871471  putative D-cysteine desulfhydrase 1, mitochondrial [KO:K05396] [EC:4.4.1.15]
103875320  D-cysteine desulfhydrase 2, mitochondrial isoform X2 [KO:K05396] [EC:4.4.1.15]
103830344  L-cysteine desulfhydrase [KO:K22207] [EC:4.4.1.28]
103874481  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
103844258  malate dehydrogenase 1, cytoplasmic [KO:K00025] [EC:1.1.1.37]
103836575  malate dehydrogenase 2, cytoplasmic [KO:K00025] [EC:1.1.1.37]
103839246  malate dehydrogenase 1, cytoplasmic [KO:K00025] [EC:1.1.1.37]
103845103  malate dehydrogenase 3, cytoplasmic [KO:K00025] [EC:1.1.1.37]
103847223  malate dehydrogenase 2, glyoxysomal [KO:K00026] [EC:1.1.1.37]
103872206  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
103873232  malate dehydrogenase, chloroplastic [KO:K00026] [EC:1.1.1.37]
103871139  malate dehydrogenase 1, mitochondrial [KO:K00026] [EC:1.1.1.37]
103832683  malate dehydrogenase 1, mitochondrial [KO:K00026] [EC:1.1.1.37]
103850366  malate dehydrogenase 2, glyoxysomal [KO:K00026] [EC:1.1.1.37]
103864390  malate dehydrogenase 1, peroxisomal [KO:K00026] [EC:1.1.1.37]
103868444  malate dehydrogenase 1, mitochondrial isoform X1 [KO:K00026] [EC:1.1.1.37]
103828203  S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent), chloroplastic [KO:K22846] [EC:2.5.1.144]
103834426  D-3-phosphoglycerate dehydrogenase 1, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
103835943  D-3-phosphoglycerate dehydrogenase 2, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
103840754  D-3-phosphoglycerate dehydrogenase 1, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
103859810  D-3-phosphoglycerate dehydrogenase 3, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
103862328  D-3-phosphoglycerate dehydrogenase 1, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
103837814  phosphoserine aminotransferase 2, chloroplastic [KO:K00831] [EC:2.6.1.52]
103834946  phosphoserine aminotransferase 1, chloroplastic [KO:K00831] [EC:2.6.1.52]
Compound
C00019  S-Adenosyl-L-methionine
C00021  S-Adenosyl-L-homocysteine
C00022  Pyruvate
C00041  L-Alanine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00065  L-Serine
C00073  L-Methionine
C00094  Sulfite
C00097  L-Cysteine
C00109  2-Oxobutanoate
C00155  L-Homocysteine
C00170  5'-Methylthioadenosine
C00197  3-Phospho-D-glycerate
C00263  L-Homoserine
C00283  Hydrogen sulfide
C00409  Methanethiol
C00441  L-Aspartate 4-semialdehyde
C00491  L-Cystine
C00506  L-Cysteate
C00606  3-Sulfino-L-alanine
C00793  D-Cysteine
C00957  Mercaptopyruvate
C00979  O-Acetyl-L-serine
C01005  O-Phospho-L-serine
C01077  O-Acetyl-L-homoserine
C01102  O-Phospho-L-homoserine
C01118  O-Succinyl-L-homoserine
C01137  S-Adenosylmethioninamine
C01180  4-Methylthio-2-oxobutanoic acid
C01234  1-Aminocyclopropane-1-carboxylate
C01817  L-Homocystine
C01962  Thiocysteine
C02218  Dehydroalanine
C02291  L-Cystathionine
C02356  (S)-2-Aminobutanoate
C02989  L-Methionine S-oxide
C03082  4-Phospho-L-aspartate
C03089  5-Methylthio-D-ribose
C03145  N-Formylmethionine
C03232  3-Phosphonooxypyruvate
C03431  S-Inosyl-L-homocysteine
C03539  S-Ribosyl-L-homocysteine
C04188  S-Methyl-5-thio-D-ribose 1-phosphate
C04582  S-Methyl-5-thio-D-ribulose 1-phosphate
C05324  Nicotianamine
C05524  Aminoacyl-L-methionine
C05526  S-Glutathionyl-L-cysteine
C05527  3-Sulfinylpyruvate
C05528  3-Sulfopyruvate
C05823  3-Mercaptolactate
C05824  S-Sulfo-L-cysteine
C06547  Ethylene
C08276  3-(Methylthio)propanoate
C09306  Sulfur dioxide
C11437  1-Deoxy-D-xylulose 5-phosphate
C11481  HSO3-
C11499  (S)-3-Sulfolactate
C11537  (2R)-3-Sulfolactate
C15606  1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one
C15650  2,3-Diketo-5-methylthiopentyl-1-phosphate
C15651  2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate
C18049  N-Acyl-L-homoserine lactone
C19787  5'-S-Methyl-5'-thioinosine
C21015  gamma-L-Glutamyl-L-2-aminobutyrate
C21016  Ophthalmate
C22359  S-Methyl-1-thio-D-xylulose 5-phosphate
Reference
PMID:15102328
  Authors
Sekowska A, Denervaud V, Ashida H, Michoud K, Haas D, Yokota A, Danchin A
  Title
Bacterial variations on the methionine salvage pathway.
  Journal
BMC Microbiol 4:9 (2004)
DOI:10.1186/1471-2180-4-9
Reference
PMID:14551435
  Authors
Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A.
  Title
A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  Journal
Science 302:286-90 (2003)
DOI:10.1126/science.1086997
Reference
PMID:12022921
  Authors
Sekowska A, Danchin A.
  Title
The methionine salvage pathway in Bacillus subtilis.
  Journal
BMC Microbiol 2:8 (2002)
DOI:10.1186/1471-2180-2-8
Reference
PMID:12670965
  Authors
Berger BJ, English S, Chan G, Knodel MH.
  Title
Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis.
  Journal
J Bacteriol 185:2418-31 (2003)
DOI:10.1128/JB.185.8.2418-2431.2003
Reference
PMID:17169919
  Authors
Goyer A, Collakova E, Shachar-Hill Y, Hanson AD
  Title
Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway.
  Journal
Plant Cell Physiol 48:232-42 (2007)
DOI:10.1093/pcp/pcl055
Reference
PMID:17030798
  Authors
Rebeille F, Jabrin S, Bligny R, Loizeau K, Gambonnet B, Van Wilder V, Douce R, Ravanel S
  Title
Methionine catabolism in Arabidopsis cells is initiated by a gamma-cleavage process and leads to S-methylcysteine and isoleucine syntheses.
  Journal
Proc Natl Acad Sci U S A 103:15687-92 (2006)
DOI:10.1073/pnas.0606195103
Reference
PMID:18625006
  Authors
Pirkov I, Norbeck J, Gustafsson L, Albers E
  Title
A complete inventory of all enzymes in the eukaryotic methionine salvage pathway.
  Journal
FEBS J 275:4111-20 (2008)
DOI:10.1111/j.1742-4658.2008.06552.x
Reference
PMID:18391471
  Authors
Ashida H, Saito Y, Kojima C, Yokota A
  Title
Enzymatic characterization of 5-methylthioribulose-1-phosphate dehydratase of the methionine salvage pathway in Bacillus subtilis.
  Journal
Biosci Biotechnol Biochem 72:959-67 (2008)
DOI:10.1271/bbb.70651
Reference
PMID:10613873
  Authors
Kitabatake M, So MW, Tumbula DL, Soll D
  Title
Cysteine biosynthesis pathway in the archaeon Methanosarcina barkeri encoded by acquired bacterial genes?
  Journal
J Bacteriol 182:143-5 (2000)
DOI:10.1128/JB.182.1.143-145.2000
Reference
PMID:12644499
  Authors
Mino K, Ishikawa K
  Title
Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
  Journal
J Bacteriol 185:2277-84 (2003)
DOI:10.1128/JB.185.7.2277-2284.2003
Reference
PMID:18520135
  Authors
Tanabe S
  Title
Development of assay methods for endogenous inorganic sulfur compounds and sulfurtransferases and evaluation of the physiological functions of bound sulfur.
  Journal
Yakugaku Zasshi 128:881-900 (2008)
DOI:10.1248/yakushi.128.881
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:19270684
  Authors
Gutierrez JA, Crowder T, Rinaldo-Matthis A, Ho MC, Almo SC, Schramm VL
  Title
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
  Journal
Nat Chem Biol 5:251-7 (2009)
DOI:10.1038/nchembio.153
Related
pathway
brp00010  Glycolysis / Gluconeogenesis
brp00250  Alanine, aspartate and glutamate metabolism
brp00260  Glycine, serine and threonine metabolism
brp00290  Valine, leucine and isoleucine biosynthesis
brp00430  Taurine and hypotaurine metabolism
brp00480  Glutathione metabolism
brp00620  Pyruvate metabolism
brp00640  Propanoate metabolism
brp00770  Pantothenate and CoA biosynthesis
brp00900  Terpenoid backbone biosynthesis
brp00920  Sulfur metabolism
KO pathway
ko00270   
LinkDB

DBGET integrated database retrieval system