KEGG   PATHWAY: ecad00061
Entry
ecad00061                   Pathway                                
Name
Fatty acid biosynthesis - Erigeron canadensis (horseweed)
Class
Metabolism; Lipid metabolism
Pathway map
ecad00061  Fatty acid biosynthesis
ecad00061

Module
ecad_M00082  Fatty acid biosynthesis, initiation [PATH:ecad00061]
ecad_M00083  Fatty acid biosynthesis, elongation [PATH:ecad00061]
ecad_M00086  beta-Oxidation, acyl-CoA synthesis [PATH:ecad00061]
Other DBs
GO: 0006633
Organism
Erigeron canadensis (horseweed) [GN:ecad]
Gene
122591066  acetyl-CoA carboxylase 1-like [KO:K11262] [EC:6.4.1.2 6.3.4.14 2.1.3.15]
122586952  acetyl-CoA carboxylase 1-like isoform X1 [KO:K11262] [EC:6.4.1.2 6.3.4.14 2.1.3.15]
122607477  acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, chloroplastic [KO:K01962] [EC:6.4.1.2 2.1.3.15]
122607369  biotin carboxyl carrier protein of acetyl-CoA carboxylase 1, chloroplastic-like [KO:K02160]
122587042  biotin carboxyl carrier protein of acetyl-CoA carboxylase, chloroplastic-like [KO:K02160]
122595067  biotin carboxylase 2, chloroplastic [KO:K01961] [EC:6.4.1.2 6.3.4.14]
122594557  acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic-like [KO:K01963] [EC:6.4.1.2 2.1.3.15]
122584315  acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [KO:K01963] [EC:6.4.1.2 2.1.3.15]
122584362  acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [KO:K01963] [EC:6.4.1.2 2.1.3.15]
54108550  accD; acetyl-CoA carboxylase carboxyltransferase beta subunit [KO:K01963] [EC:6.4.1.2 2.1.3.15]
122588606  probable CoA ligase CCL8 [KO:K18660] [EC:6.2.1.76 6.2.1.-]
122582693  malonyl CoA-acyl carrier protein transacylase [KO:K00645] [EC:2.3.1.39]
122578317  3-oxoacyl-[acyl-carrier-protein] synthase 3 B, chloroplastic-like [KO:K00648] [EC:2.3.1.180]
122604161  3-oxoacyl-[acyl-carrier-protein] synthase 3 A, chloroplastic-like [KO:K00648] [EC:2.3.1.180]
122592740  3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial [KO:K09458] [EC:2.3.1.179]
122592757  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic [KO:K09458] [EC:2.3.1.179]
122582095  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic-like isoform X1 [KO:K09458] [EC:2.3.1.179]
122582675  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
122583243  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
122596727  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
122597866  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
122599470  3-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
122587136  3-oxoacyl-[acyl-carrier-protein] synthase II, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
122601774  3-oxoacyl-[acyl-carrier-protein] synthase I, chloroplastic-like [KO:K09458] [EC:2.3.1.179]
122578214  NADPH-dependent aldehyde reductase-like protein, chloroplastic [KO:K00059] [EC:1.1.1.100]
122578225  NADPH-dependent aldehyde reductase-like protein, chloroplastic [KO:K00059] [EC:1.1.1.100]
122578437  3-oxoacyl-[acyl-carrier-protein] reductase 4 [KO:K00059] [EC:1.1.1.100]
122609925  NADPH-dependent aldehyde reductase-like protein, chloroplastic [KO:K00059] [EC:1.1.1.100]
122595023  3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ-like [KO:K02372] [EC:4.2.1.59]
122599889  3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ-like [KO:K02372] [EC:4.2.1.59]
122603967  enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic-like isoform X1 [KO:K00208] [EC:1.3.1.9 1.3.1.10]
122594264  enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic-like [KO:K00208] [EC:1.3.1.9 1.3.1.10]
122595172  enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic-like [KO:K00208] [EC:1.3.1.9 1.3.1.10]
122595613  enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic-like [KO:K00208] [EC:1.3.1.9 1.3.1.10]
122597971  enoyl-[acyl-carrier-protein] reductase [NADH] 1, chloroplastic-like [KO:K00208] [EC:1.3.1.9 1.3.1.10]
122592726  enoyl-[acyl-carrier-protein] reductase, mitochondrial [KO:K07512] [EC:1.3.1.- 1.3.1.38]
122592278  palmitoyl-acyl carrier protein thioesterase, chloroplastic-like [KO:K10781] [EC:3.1.2.14 3.1.2.21]
122608756  acyl-[acyl-carrier-protein] hydrolase FATB2, chloroplastic-like [KO:K10781] [EC:3.1.2.14 3.1.2.21]
122597131  palmitoyl-acyl carrier protein thioesterase, chloroplastic-like [KO:K10781] [EC:3.1.2.14 3.1.2.21]
122597133  palmitoyl-acyl carrier protein thioesterase, chloroplastic-like [KO:K10781] [EC:3.1.2.14 3.1.2.21]
122597659  palmitoyl-acyl carrier protein thioesterase, chloroplastic-like [KO:K10781] [EC:3.1.2.14 3.1.2.21]
122597666  palmitoyl-acyl carrier protein thioesterase, chloroplastic-like [KO:K10781] [EC:3.1.2.14 3.1.2.21]
122610689  palmitoyl-acyl carrier protein thioesterase, chloroplastic-like [KO:K10781] [EC:3.1.2.14 3.1.2.21]
122599234  palmitoyl-acyl carrier protein thioesterase, chloroplastic [KO:K10781] [EC:3.1.2.14 3.1.2.21]
122593151  oleoyl-acyl carrier protein thioesterase, chloroplastic [KO:K10782] [EC:3.1.2.14]
122607085  oleoyl-acyl carrier protein thioesterase, chloroplastic-like [KO:K10782] [EC:3.1.2.14]
122582778  oleoyl-acyl carrier protein thioesterase, chloroplastic-like [KO:K10782] [EC:3.1.2.14]
122581127  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
122581888  stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic-like [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
122589292  stearoyl-[acyl-carrier-protein] 9-desaturase 6, chloroplastic [KO:K03921] [EC:1.14.19.2 1.14.19.11 1.14.19.26]
122590551  long chain acyl-CoA synthetase 1-like [KO:K01897] [EC:6.2.1.3]
122592124  long chain acyl-CoA synthetase 1-like [KO:K01897] [EC:6.2.1.3]
122593221  long chain acyl-CoA synthetase 8 [KO:K01897] [EC:6.2.1.3]
122606679  long chain acyl-CoA synthetase 1-like [KO:K01897] [EC:6.2.1.3]
122581507  probable acyl-activating enzyme 16, chloroplastic [KO:K01897] [EC:6.2.1.3]
122581595  probable acyl-activating enzyme 16, chloroplastic [KO:K01897] [EC:6.2.1.3]
122595127  long chain acyl-CoA synthetase 6, peroxisomal-like [KO:K01897] [EC:6.2.1.3]
122595245  probable CoA ligase CCL6 [KO:K01897] [EC:6.2.1.3]
122583497  probable acyl-activating enzyme 16, chloroplastic [KO:K01897] [EC:6.2.1.3]
122584791  long chain acyl-CoA synthetase 4-like [KO:K01897] [EC:6.2.1.3]
122586847  long chain acyl-CoA synthetase 9, chloroplastic isoform X1 [KO:K01897] [EC:6.2.1.3]
122599138  long chain acyl-CoA synthetase 4-like [KO:K01897] [EC:6.2.1.3]
122599851  long chain acyl-CoA synthetase 4-like [KO:K01897] [EC:6.2.1.3]
122599967  long chain acyl-CoA synthetase 6, peroxisomal-like [KO:K01897] [EC:6.2.1.3]
Compound
C00024  Acetyl-CoA
C00083  Malonyl-CoA
C00154  Palmitoyl-CoA
C00173  Acyl-[acyl-carrier protein]
C00229  Acyl-carrier protein
C00249  Hexadecanoic acid
C00383  Malonate
C00638  Long-chain fatty acid
C00685  3-Oxoacyl-[acyl-carrier protein]
C00693  trans-2,3-Dehydroacyl-[acyl-carrier protein]
C00712  (9Z)-Octadecenoic acid
C01203  Oleoyl-[acyl-carrier protein]
C01209  Malonyl-[acyl-carrier protein]
C01271  (3R)-3-Hydroxyacyl-[acyl-carrier protein]
C01530  Octadecanoic acid
C01571  Decanoic acid
C02679  Dodecanoic acid
C02843  Long-chain acyl-CoA
C03939  Acetyl-[acyl-carrier protein]
C04088  Octadecanoyl-[acyl-carrier protein]
C04180  cis-Dec-3-enoyl-[acp]
C04246  But-2-enoyl-[acyl-carrier protein]
C04618  (3R)-3-Hydroxybutanoyl-[acyl-carrier protein]
C04619  (3R)-3-Hydroxydecanoyl-[acyl-carrier protein]
C04620  (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein]
C04633  (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
C04688  (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
C05223  Dodecanoyl-[acyl-carrier protein]
C05744  Acetoacetyl-[acp]
C05745  Butyryl-[acp]
C05746  3-Oxohexanoyl-[acp]
C05747  (3R)-3-Hydroxyhexanoyl-[acyl-carrier protein]
C05748  trans-Hex-2-enoyl-[acp]
C05749  Hexanoyl-[acp]
C05750  3-Oxooctanoyl-[acp]
C05751  trans-Oct-2-enoyl-[acp]
C05752  Octanoyl-[acp]
C05753  3-Oxodecanoyl-[acp]
C05754  trans-Dec-2-enoyl-[acp]
C05755  Decanoyl-[acp]
C05756  3-Oxododecanoyl-[acp]
C05757  (3R)-3-Hydroxydodecanoyl-[acyl-carrier protein]
C05758  trans-Dodec-2-enoyl-[acp]
C05759  3-Oxotetradecanoyl-[acp]
C05760  trans-Tetradec-2-enoyl-[acp]
C05761  Tetradecanoyl-[acp]
C05762  3-Oxohexadecanoyl-[acp]
C05763  trans-Hexadec-2-enoyl-[acp]
C05764  Hexadecanoyl-[acp]
C06423  Octanoic acid
C06424  Tetradecanoic acid
C08362  (9Z)-Hexadecenoic acid
C16219  3-Oxostearoyl-[acp]
C16220  (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein]
C16221  (2E)-Octadecenoyl-[acp]
C16520  Hexadecenoyl-[acyl-carrier protein]
C20683  Long-chain acyl-[acyl-carrier protein]
C20794  n-7 Unsaturated acyl-[acyl-carrier protein]
Reference
PMID:12061798
  Authors
Salas JJ, Ohlrogge JB.
  Title
Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases.
  Journal
Arch Biochem Biophys 403:25-34 (2002)
DOI:10.1016/S0003-9861(02)00017-6
Reference
PMID:12518017
  Authors
Zhang YM, Marrakchi H, White SW, Rock CO.
  Title
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.
  Journal
J Lipid Res 44:1-10 (2003)
DOI:10.1194/jlr.R200016-JLR200
Reference
PMID:11337402
  Authors
Voelker T, Kinney AJ.
  Title
VARIATIONS IN THE BIOSYNTHESIS OF SEED-STORAGE LIPIDS.
  Journal
Annu Rev Plant Physiol Plant Mol Biol 52:335-361 (2001)
DOI:10.1146/annurev.arplant.52.1.335
Reference
PMID:17573542
  Authors
Barker GC, Larson TR, Graham IA, Lynn JR, King GJ.
  Title
Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait Loci analysis of the Brassica C genome.
  Journal
Plant Physiol 144:1827-42 (2007)
DOI:10.1104/pp.107.096172
Reference
PMID:30201289
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
PMID:25203508
  Authors
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z
  Title
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
  Journal
Nat Commun 5:4805 (2014)
DOI:10.1038/ncomms5805
Reference
PMID:19686777
  Authors
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ
  Title
Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.
  Journal
Prog Lipid Res 49:27-45 (2010)
DOI:10.1016/j.plipres.2009.08.001
Reference
PMID:27553474
  Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
  Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
  Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:10.1016/j.bbalip.2016.08.011
Related
pathway
ecad00020  Citrate cycle (TCA cycle)
ecad00062  Fatty acid elongation
ecad00071  Fatty acid degradation
ecad00410  beta-Alanine metabolism
ecad00561  Glycerolipid metabolism
ecad00564  Glycerophospholipid metabolism
ecad00620  Pyruvate metabolism
ecad00785  Lipoic acid metabolism
KO pathway
ko00061   
LinkDB

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