KEGG   PATHWAY: mlf04514
Entry
mlf04514                    Pathway                                
Name
Cell adhesion molecules - Myotis lucifugus (little brown bat)
Description
Cell adhesion molecules (CAMs) are (glyco)proteins expressed on the cell surface and play a critical role in a wide array of biologic processes that include hemostasis, the immune response, inflammation, embryogenesis, and development of neuronal tissue. There are four main groups: the integrin family, the immunoglobulin superfamily, selectins, and cadherins. Membrane proteins that mediate immune cell–cell interactions fall into different categories, namely those involved in antigen recognition, costimulation and cellular adhesion. Furthermore cell-cell adhesions are important for brain morphology and highly coordinated brain functions such as memory and learning. During early development of the nervous system, neurons elongate their axons towards their targets and establish and maintain synapses through formation of cell-cell adhesions. Cell-cell adhesions also underpin axon-axon contacts and link neurons with supporting schwann cells and oligodendrocytes.
Class
Environmental Information Processing; Signaling molecules and interaction
Pathway map
mlf04514  Cell adhesion molecules
mlf04514

Other DBs
GO: 0050839
Organism
Myotis lucifugus (little brown bat) [GN:mlf]
Gene
102431808  CD58; lymphocyte function-associated antigen 3 isoform X5 [KO:K06492]
102431496  CD2; T-cell surface antigen CD2 [KO:K06449]
102424295  VSIR; V-type immunoglobulin domain-containing suppressor of T-cell activation [KO:K23268]
102423993  IGSF11; LOW QUALITY PROTEIN: immunoglobulin superfamily member 11 [KO:K06791]
102417504  CD80; T-lymphocyte activation antigen CD80 isoform X1 [KO:K05412]
102421288  CD274; programmed cell death 1 ligand 1 isoform X2 [KO:K06745]
102438564  CD28; T-cell-specific surface glycoprotein CD28 [KO:K06470]
102436777  CD86; T-lymphocyte activation antigen CD86 isoform X1 [KO:K05413]
102420915  CTLA4; cytotoxic T-lymphocyte protein 4 isoform X1 [KO:K06538]
102419600  ICOS ligand-like isoform X1 [KO:K06710]
102438862  ICOS; inducible T-cell costimulator [KO:K06713]
102433442  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
111822996  HLA class II histocompatibility antigen, DQ beta 1 chain-like [KO:K06752]
111823581  HLA class II histocompatibility antigen, DQ beta 1 chain-like [KO:K06752]
102424361  HLA class II histocompatibility antigen, DQ alpha 2 chain-like [KO:K06752]
102424046  boLa class II histocompatibility antigen, DQB*0101 beta chain-like [KO:K06752]
102426046  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
102417581  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
102417899  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
102418225  HLA class II histocompatibility antigen, DRB1-4 beta chain-like [KO:K06752]
102416953  SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like [KO:K06752]
102421254  HLA class II histocompatibility antigen, DM beta chain [KO:K06752]
102423761  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
102441293  SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like [KO:K06752]
102418131  HLA class II histocompatibility antigen, DR alpha chain-like [KO:K06752]
102434058  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
102434372  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
111824054  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
102443188  HLA class II histocompatibility antigen, DQ alpha 2 chain-like [KO:K06752]
102431574  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
102431885  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
102417382  SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like [KO:K06752]
102431149  HLA class II histocompatibility antigen, DRB1-9 beta chain-like [KO:K06752]
102417268  HLA class II histocompatibility antigen, DQ beta 1 chain-like [KO:K06752]
102439327  SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like [KO:K06752]
106694679  SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like [KO:K06752]
102426241  HLA class II histocompatibility antigen, DQ alpha 2 chain-like [KO:K06752]
102423747  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
102433751  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
106695222  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
102422459  HLA class II histocompatibility antigen, DM alpha chain [KO:K06752]
102419180  SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like [KO:K06752]
102441506  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
102428157  DLA class II histocompatibility antigen, DR-1 beta chain-like [KO:K06752]
102431769  HLA class II histocompatibility antigen, DRB1-4 beta chain-like [KO:K06752]
102418553  SLA class II histocompatibility antigen, DQ haplotype C beta chain-like [KO:K06752]
102419081  RLA class II histocompatibility antigen, DP alpha-1 chain-like [KO:K06752]
102423684  HLA class II histocompatibility antigen, DP beta 1 chain-like isoform X1 [KO:K06752]
102429593  H-2 class II histocompatibility antigen, E-S beta chain-like [KO:K06752]
102423144  SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like isoform X2 [KO:K06752]
102423440  boLa class II histocompatibility antigen, DQB*0101 beta chain-like [KO:K06752]
102423734  SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like [KO:K06752]
102425725  HLA class II histocompatibility antigen, DR alpha chain-like [KO:K06752]
102426355  SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like [KO:K06752]
102424057  DLA class II histocompatibility antigen, DR-1 beta chain-like isoform X1 [KO:K06752]
102424373  HLA class II histocompatibility antigen, DR beta 5 chain-like [KO:K06752]
102427698  CD4; T-cell surface glycoprotein CD4 [KO:K06454]
102440675  HLA class I histocompatibility antigen, B-46 alpha chain-like isoform X10 [KO:K06751]
102442541  HLA class I histocompatibility antigen, B-15 alpha chain-like [KO:K06751]
102433344  HLA class I histocompatibility antigen, B-67 alpha chain-like isoform X2 [KO:K06751]
102438185  patr class I histocompatibility antigen, A-126 alpha chain-like isoform X2 [KO:K06751]
102435002  HLA class I histocompatibility antigen, B-67 alpha chain-like isoform X3 [KO:K06751]
102429481  HLA class I histocompatibility antigen, B-67 alpha chain-like isoform X12 [KO:K06751]
111822980  patr class I histocompatibility antigen, A-126 alpha chain-like isoform X3 [KO:K06751]
111822961  HLA class I histocompatibility antigen, B-15 alpha chain-like [KO:K06751]
102432715  patr class I histocompatibility antigen, B-2 alpha chain-like isoform X6 [KO:K06751]
102429581  saoe class I histocompatibility antigen, A alpha chain-like isoform X1 [KO:K06751]
102417058  HLA class I histocompatibility antigen, A-11 alpha chain-like [KO:K06751]
102435927  HLA class I histocompatibility antigen, B-67 alpha chain-like isoform X1 [KO:K06751]
102431662  HLA class I histocompatibility antigen, B-18 alpha chain-like isoform X1 [KO:K06751]
102428684  HLA class I histocompatibility antigen, B-57 alpha chain-like [KO:K06751]
102418243  class I histocompatibility antigen, Gogo-B*0103 alpha chain-like isoform X1 [KO:K06751]
102424088  H-2 class I histocompatibility antigen, alpha chain-like isoform X1 [KO:K06751]
102440606  HLA class I histocompatibility antigen, B-54 alpha chain-like isoform X1 [KO:K06751]
102416963  patr class I histocompatibility antigen, B-1 alpha chain-like [KO:K06751]
111823006  saoe class I histocompatibility antigen, A alpha chain-like [KO:K06751]
102431053  HLA class I histocompatibility antigen, B-82 alpha chain-like [KO:K06751]
102442224  HLA class I histocompatibility antigen, B-14 alpha chain-like [KO:K06751]
102438496  patr class I histocompatibility antigen, A-126 alpha chain-like isoform X1 [KO:K06751]
102441816  patr class I histocompatibility antigen, A-108 alpha chain-like isoform X1 [KO:K06751]
102418018  class I histocompatibility antigen, Gogo-B*0103 alpha chain-like [KO:K06751]
102422972  HLA class I histocompatibility antigen, B-57 alpha chain-like [KO:K06751]
102424815  HLA class I histocompatibility antigen, B-45 alpha chain-like isoform X3 [KO:K06751]
102422085  class I histocompatibility antigen, Gogo-B*0102 alpha chain-like [KO:K06751]
102424768  HLA class I histocompatibility antigen, B-15 alpha chain-like [KO:K06751]
102417991  BOLA class I histocompatibility antigen, alpha chain BL3-7-like [KO:K06751]
102431421  CD8B; T-cell surface glycoprotein CD8 beta chain [KO:K06459]
102421589  PDCD1LG2; programmed cell death 1 ligand 2 isoform X1 [KO:K06708]
102425787  VTCN1; V-set domain-containing T-cell activation inhibitor 1 [KO:K06747]
102423936  PDCD1; programmed cell death protein 1 isoform X1 [KO:K06744]
102439545  CD40; tumor necrosis factor receptor superfamily member 5 [KO:K03160]
102433204  CD40LG; CD40 ligand [KO:K03161]
102432309  ALCAM; CD166 antigen isoform X1 [KO:K06547]
102437788  LOW QUALITY PROTEIN: T-cell differentiation antigen CD6-like [KO:K06456]
102434505  CD226; CD226 antigen [KO:K06567]
102422476  nectin-2-like [KO:K06531]
102418061  TIGIT; T-cell immunoreceptor with Ig and ITIM domains [KO:K16350]
102436734  ITGAL; integrin alpha-L isoform X2 [KO:K05718]
102425275  ITGB2; integrin beta-2 [KO:K06464]
102436833  ICAM1; intercellular adhesion molecule 1 [KO:K06490]
102419717  ICAM2; intercellular adhesion molecule 2 [KO:K06523]
102434456  ICAM3; LOW QUALITY PROTEIN: intercellular adhesion molecule 3 [KO:K06486]
102435553  CD22; B-cell receptor CD22 [KO:K06467]
102437730  SIGLEC1; LOW QUALITY PROTEIN: sialoadhesin [KO:K06548]
102417034  SPN; leukosialin [KO:K06477]
102430432  NECTIN3; nectin-3 isoform X1 [KO:K06592]
102438156  CLDN18; claudin-18 isoform X1 [KO:K06087]
102424673  CLDN12; claudin-12 [KO:K06087]
102438830  CLDN20; claudin-20 [KO:K06087]
102416848  CLDN15; claudin-15 [KO:K06087]
102439944  CLDN24; putative claudin-24 [KO:K06087]
102429393  claudin-18 isoform X1 [KO:K06087]
106694619  claudin-34-like [KO:K06087]
106694621  claudin-34-like [KO:K06087]
102440260  claudin-22 [KO:K06087]
102428455  CLDN19; claudin-19 [KO:K06087]
102422437  CLDN16; LOW QUALITY PROTEIN: claudin-16 [KO:K06087]
102422744  CLDN1; claudin-1 [KO:K06087]
102428380  CLDN17; claudin-17 [KO:K06087]
102436769  CLDN10; claudin-10 isoform X1 [KO:K06087]
102426949  CLDN5; claudin-5 [KO:K06087]
102435739  CLDN9; claudin-9 [KO:K06087]
102426331  CLDN2; claudin-2 [KO:K06087]
102432829  CLDN4; claudin-4 [KO:K06087]
102434482  claudin-34-like [KO:K06087]
102434797  claudin-34-like [KO:K06087]
102418444  CLDN11; claudin-11 [KO:K06087]
102435433  CLDN6; claudin-6 [KO:K06087]
102418839  CLDN7; claudin-7 [KO:K06087]
102421308  OCLN; occludin isoform X1 [KO:K06088]
102441066  F11R; junctional adhesion molecule A [KO:K06089]
102430335  JAM2; LOW QUALITY PROTEIN: junctional adhesion molecule B [KO:K06735]
102437004  JAM3; junctional adhesion molecule C [KO:K06785]
102429998  CDH5; cadherin-5 [KO:K06533]
102418361  PECAM1; platelet endothelial cell adhesion molecule isoform X1 [KO:K06471]
102435208  CD99L2; CD99 antigen-like protein 2 isoform X4 [KO:K06520]
102433795  SELPLG; P-selectin glycoprotein ligand 1 isoform X2 [KO:K06544]
102429128  SELP; P-selectin [KO:K06496]
102439596  ITGA4; integrin alpha-4 [KO:K06483]
102438984  ITGB1; integrin beta-1 isoform X1 [KO:K05719]
102438448  ITGA9; integrin alpha-9 [KO:K06585]
102438271  VCAM1; vascular cell adhesion protein 1 [KO:K06527]
102418373  ITGB7; integrin beta-7 [KO:K06590]
102432785  MADCAM1; mucosal addressin cell adhesion molecule 1 [KO:K06779]
102429436  SELL; L-selectin [KO:K06495]
102420992  CD34; hematopoietic progenitor cell antigen CD34 isoform X2 [KO:K06474]
102432953  GLG1; Golgi apparatus protein 1 [KO:K06816]
102425896  SELE; E-selectin isoform X4 [KO:K06494]
102438921  NECTIN1; nectin-1 [KO:K06081]
102440510  CDH2; cadherin-2 [KO:K06736]
102429021  NCAM2; neural cell adhesion molecule 2 isoform X1 [KO:K06491]
102433895  NCAM1; LOW QUALITY PROTEIN: neural cell adhesion molecule 1 [KO:K06491]
102422358  L1CAM; neural cell adhesion molecule L1 isoform X1 [KO:K06550]
102418078  CADM1; cell adhesion molecule 1 isoform X1 [KO:K06781]
102417952  NEGR1; neuronal growth regulator 1 isoform X1 [KO:K06775]
102421049  LOW QUALITY PROTEIN: netrin-G1 [KO:K07522]
102429736  leucine-rich repeat-containing protein 4C [KO:K07523]
102419604  LRRC4; leucine-rich repeat-containing protein 4 [KO:K16351]
102440978  PTPRF; receptor-type tyrosine-protein phosphatase F [KO:K05695] [EC:3.1.3.48]
102424619  SDC1; LOW QUALITY PROTEIN: syndecan-1 [KO:K06257]
102431955  SDC2; syndecan-2 [KO:K16336]
102439812  SDC3; LOW QUALITY PROTEIN: syndecan-3 [KO:K16337]
102428484  SDC4; syndecan-4 isoform X1 [KO:K16338]
102439153  ITGAV; integrin alpha-V [KO:K06487]
102435389  ITGB8; integrin beta-8 isoform X1 [KO:K06591]
102422404  ITGA8; integrin alpha-8 [KO:K06584]
102425083  NRXN1; neurexin-1 [KO:K07377]
102422959  NRXN3; neurexin 3 isoform X2 [KO:K07377]
102438026  NLGN1; neuroligin-1 isoform X3 [KO:K07378]
102439918  NLGN3; neuroligin-3 isoform X1 [KO:K07378]
102434011  PTPRS; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase S [KO:K06778] [EC:3.1.3.48]
102429165  SLITRK1; SLIT and NTRK-like protein 1 [KO:K25832]
102419285  SLITRK2; SLIT and NTRK-like protein 2 [KO:K25833]
102419901  SLITRK4; SLIT and NTRK-like protein 4 [KO:K25835]
102426986  SLITRK5; LOW QUALITY PROTEIN: SLIT and NTRK-like protein 5 [KO:K25836]
102427924  SLITRK6; SLIT and NTRK-like protein 6 [KO:K25837]
102438469  receptor-type tyrosine-protein phosphatase delta [KO:K06777] [EC:3.1.3.48]
102429691  SLITRK3; LOW QUALITY PROTEIN: SLIT and NTRK-like protein 3 [KO:K25834]
102437307  CADM3; cell adhesion molecule 3 [KO:K06780]
102437851  NRCAM; neuronal cell adhesion molecule [KO:K06756]
102437777  CNTN1; LOW QUALITY PROTEIN: contactin-1 [KO:K06759]
102420964  PTPRM; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase mu [KO:K05693] [EC:3.1.3.48]
102420249  CNTN2; LOW QUALITY PROTEIN: contactin-2 [KO:K06760]
102439660  NFASC; neurofascin [KO:K06757]
102423997  CNTNAP1; LOW QUALITY PROTEIN: contactin-associated protein 1 [KO:K07379]
102424917  CNTNAP2; contactin-associated protein-like 2 [KO:K07380]
102419662  MPZ; myelin protein P0 isoform X1 [KO:K06770]
102429323  MAG; myelin-associated glycoprotein isoform X1 [KO:K06771]
102430843  CDH1; cadherin-1 isoform X2 [KO:K05689]
102440428  VCAN; versican core protein isoform X1 [KO:K06793]
102426340  ITGA6; integrin alpha-6 isoform X1 [KO:K06485]
102430113  CDH3; cadherin-3 [KO:K06796]
102435357  CDH15; cadherin-15 [KO:K06809]
102435928  NEO1; neogenin [KO:K06766]
Reference
  Authors
Barclay AN.
  Title
Membrane proteins with immunoglobulin-like domains--a master superfamily of interaction molecules.
  Journal
Semin Immunol 15:215-23 (2003)
DOI:10.1016/S1044-5323(03)00047-2
Reference
  Authors
Sharpe AH, Freeman GJ.
  Title
The B7-CD28 superfamily.
  Journal
Nat Rev Immunol 2:116-26 (2002)
DOI:10.1038/nri727
Reference
PMID:9597126
  Authors
Grewal IS, Flavell RA.
  Title
CD40 and CD154 in cell-mediated immunity.
  Journal
Annu Rev Immunol 16:111-35 (1998)
DOI:10.1146/annurev.immunol.16.1.111
Reference
  Authors
Dardalhon V, Schubart AS, Reddy J, Meyers JH, Monney L, Sabatos CA, Ahuja R, Nguyen K, Freeman GJ, Greenfield EA, Sobel RA, Kuchroo VK.
  Title
CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functions.
  Journal
J Immunol 175:1558-65 (2005)
DOI:10.4049/jimmunol.175.3.1558
Reference
  Authors
Montoya MC, Sancho D, Vicente-Manzanares M, Sanchez-Madrid F.
  Title
Cell adhesion and polarity during immune interactions.
  Journal
Immunol Rev 186:68-82 (2002)
DOI:10.1034/j.1600-065X.2002.18607.x
Reference
  Authors
Dejana E.
  Title
Endothelial cell-cell junctions: happy together.
  Journal
Nat Rev Mol Cell Biol 5:261-70 (2004)
DOI:10.1038/nrm1357
Reference
  Authors
Bazzoni G.
  Title
The JAM family of junctional adhesion molecules.
  Journal
Curr Opin Cell Biol 15:525-30 (2003)
DOI:10.1016/S0955-0674(03)00104-2
Reference
  Authors
Becker BF, Heindl B, Kupatt C, Zahler S.
  Title
Endothelial function and hemostasis.
  Journal
Z Kardiol 89:160-7 (2000)
DOI:10.1007/PL00007320
Reference
PMID:9150551
  Authors
Elangbam CS, Qualls CW Jr, Dahlgren RR.
  Title
Cell adhesion molecules--update.
  Journal
Vet Pathol 34:61-73 (1997)
DOI:10.1177/030098589703400113
Reference
  Authors
Muller WA.
  Title
Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response.
  Journal
Trends Immunol 24:327-34 (2003)
DOI:10.1016/S1471-4906(03)00117-0
Reference
  Authors
Yamagata M, Sanes JR, Weiner JA.
  Title
Synaptic adhesion molecules.
  Journal
Curr Opin Cell Biol 15:621-32 (2003)
DOI:10.1016/S0955-0674(03)00107-8
Reference
  Authors
Ethell IM, Pasquale EB.
  Title
Molecular mechanisms of dendritic spine development and remodeling.
  Journal
Prog Neurobiol 75:161-205 (2005)
DOI:10.1016/j.pneurobio.2005.02.003
Reference
  Authors
Benson DL, Schnapp LM, Shapiro L, Huntley GW.
  Title
Making memories stick: cell-adhesion molecules in synaptic plasticity.
  Journal
Trends Cell Biol 10:473-82 (2000)
DOI:10.1016/S0962-8924(00)01838-9
Reference
  Authors
Rosdahl JA, Mourton TL, Brady-Kalnay SM.
  Title
Protein kinase C delta (PKCdelta) is required for protein tyrosine phosphatase mu (PTPmu)-dependent neurite outgrowth.
  Journal
Mol Cell Neurosci 19:292-306 (2002)
DOI:10.1006/mcne.2001.1071
Reference
  Authors
Dunican DJ, Doherty P.
  Title
The generation of localized calcium rises mediated by cell adhesion molecules and their role in neuronal growth cone motility.
  Journal
Mol Cell Biol Res Commun 3:255-63 (2000)
DOI:10.1006/mcbr.2000.0225
Reference
  Authors
Girault JA, Peles E.
  Title
Development of nodes of Ranvier.
  Journal
Curr Opin Neurobiol 12:476-85 (2002)
DOI:10.1016/S0959-4388(02)00370-7
Reference
  Authors
Arroyo EJ, Scherer SS.
  Title
On the molecular architecture of myelinated fibers.
  Journal
Histochem Cell Biol 113:1-18 (2000)
DOI:10.1007/s004180050001
Reference
  Authors
Salzer JL.
  Title
Polarized domains of myelinated axons.
  Journal
Neuron 40:297-318 (2003)
DOI:10.1016/S0896-6273(03)00628-7
Reference
  Authors
Irie K, Shimizu K, Sakisaka T, Ikeda W, Takai Y.
  Title
Roles and modes of action of nectins in cell-cell adhesion.
  Journal
Semin Cell Dev Biol 15:643-56 (2004)
DOI:10.1016/j.semcdb.2004.09.002
Reference
  Authors
Nakanishi H, Takai Y.
  Title
Roles of nectins in cell adhesion, migration and polarization.
  Journal
Biol Chem 385:885-92 (2004)
DOI:10.1515/BC.2004.116
Reference
  Authors
Siu MK, Cheng CY.
  Title
Extracellular matrix: recent advances on its role in junction dynamics in the seminiferous epithelium during spermatogenesis.
  Journal
Biol Reprod 71:375-91 (2004)
DOI:10.1095/biolreprod.104.028225
Reference
  Authors
Lee NP, Cheng CY.
  Title
Adaptors, junction dynamics, and spermatogenesis.
  Journal
Biol Reprod 71:392-404 (2004)
DOI:10.1095/biolreprod.104.027268
Reference
  Authors
Inagaki M, Irie K, Ishizaki H, Tanaka-Okamoto M, Morimoto K, Inoue E, Ohtsuka T, Miyoshi J, Takai Y.
  Title
Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development.
  Journal
Development 132:1525-37 (2005)
DOI:10.1242/dev.01697
Reference
  Authors
Marthiens V, Gavard J, Lambert M, Mege RM.
  Title
Cadherin-based cell adhesion in neuromuscular development.
  Journal
Biol Cell 94:315-26 (2002)
DOI:10.1016/S0248-4900(02)00005-9
Reference
  Authors
Krauss RS, Cole F, Gaio U, Takaesu G, Zhang W, Kang JS.
  Title
Close encounters: regulation of vertebrate skeletal myogenesis by cell-cell contact.
  Journal
J Cell Sci 118:2355-62 (2005)
DOI:10.1242/jcs.02397
Related
pathway
mlf04520  Adherens junction
mlf04530  Tight junction
mlf04610  Complement and coagulation cascades
mlf04660  T cell receptor signaling pathway
mlf04670  Leukocyte transendothelial migration
KO pathway
ko04514   
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