Entry
Symbol
PTPRF, LAR
Name
receptor-type tyrosine-protein phosphatase F [EC:
3.1.3.48 ]
Pathway
Disease
H02811 Aplasia or hypoplasia of the breasts and/or nipples
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04514 Cell adhesion molecules
K05695 PTPRF, LAR; receptor-type tyrosine-protein phosphatase F
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
K05695 PTPRF, LAR; receptor-type tyrosine-protein phosphatase F
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
K05695 PTPRF, LAR; receptor-type tyrosine-protein phosphatase F
09160 Human Diseases
09167 Endocrine and metabolic disease
04931 Insulin resistance
K05695 PTPRF, LAR; receptor-type tyrosine-protein phosphatase F
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins
K05695 PTPRF, LAR; receptor-type tyrosine-protein phosphatase F
Enzymes [BR:ko01000 ]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
K05695 PTPRF, LAR; receptor-type tyrosine-protein phosphatase F
Protein phosphatases and associated proteins [BR:ko01009 ]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Receptor PTPs
K05695 PTPRF, LAR; receptor-type tyrosine-protein phosphatase F
BRITE hierarchy
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Genes
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Taxonomy UniProt
Reference
Authors
Chagnon MJ, Uetani N, Tremblay ML
Title
Functional significance of the LAR receptor protein tyrosine phosphatase family in development and diseases.
Journal
Reference
Authors
Yang T, Massa SM, Longo FM
Title
LAR protein tyrosine phosphatase receptor associates with TrkB and modulates neurotrophic signaling pathways.
Journal
Reference
Authors
Harrington RJ, Gutch MJ, Hengartner MO, Tonks NK, Chisholm AD
Title
The C. elegans LAR-like receptor tyrosine phosphatase PTP-3 and the VAB-1 Eph receptor tyrosine kinase have partly redundant functions in morphogenesis.
Journal
Development 129:2141-53 (2002)
Sequence
LinkDB
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