KEGG   PATHWAY: rtd00830
Entry
rtd00830                    Pathway                                
Name
Retinol metabolism - Rissa tridactyla (black-legged kittiwake)
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
rtd00830  Retinol metabolism
rtd00830

Other DBs
GO: 0006776
Organism
Rissa tridactyla (black-legged kittiwake) [GN:rtd]
Gene
128909196  BCO1; beta,beta-carotene 15,15'-dioxygenase [KO:K00515] [EC:1.13.11.63]
128909877  alcohol dehydrogenase 1 isoform X1 [KO:K13951] [EC:1.1.1.1]
128910002  alcohol dehydrogenase 1-like isoform X1 [KO:K13951] [EC:1.1.1.1]
128910001  alcohol dehydrogenase class-3 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
128918294  DHRS3; short-chain dehydrogenase/reductase 3 isoform X1 [KO:K11146] [EC:1.1.1.300]
128903905  LOW QUALITY PROTEIN: dehydrogenase/reductase SDR family member 4-like [KO:K11147] [EC:1.1.-.-]
128912491  DHRS9; dehydrogenase/reductase SDR family member 9 isoform X1 [KO:K11149] [EC:1.1.-.-]
128901441  RDH8; retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
128919323  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
128914300  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
128904997  RDH10; retinol dehydrogenase 10 isoform X1 [KO:K11151] [EC:1.1.1.-]
128908200  retinol dehydrogenase 12-like [KO:K11153] [EC:1.1.1.300]
128903211  retinol dehydrogenase 16-like isoform X1 [KO:K11154] [EC:1.1.1.-]
128903212  retinol dehydrogenase 16-like [KO:K11154] [EC:1.1.1.-]
128905657  short-chain dehydrogenase/reductase family 16C member 6-like [KO:K15734] [EC:1.1.1.105]
128905813  SDR16C5; epidermal retinol dehydrogenase 2 [KO:K15734] [EC:1.1.1.105]
128910162  LRAT; lecithin retinol acyltransferase [KO:K00678] [EC:2.3.1.135]
128916356  PNPLA4; patatin-like phospholipase domain-containing protein 4 isoform X1 [KO:K11157] [EC:3.1.1.-]
128913919  RPE65; retinoid isomerohydrolase [KO:K11158] [EC:3.1.1.64 5.3.3.22]
128903176  RDH5; retinol dehydrogenase 5 [KO:K00061] [EC:1.1.1.315]
128912438  AOX1; aldehyde oxidase isoform X1 [KO:K00157] [EC:1.2.3.1]
128914644  ALDH1A2; retinal dehydrogenase 2 isoform X1 [KO:K07249] [EC:1.2.1.36]
128902872  ALDH1A1; aldehyde dehydrogenase 1A1 [KO:K07249] [EC:1.2.1.36]
128915126  ALDH1A3; aldehyde dehydrogenase family 1 member A3 [KO:K07249] [EC:1.2.1.36]
128911658  cytochrome P450 26A1 [KO:K07437] [EC:1.14.14.-]
128910116  cytochrome P450 26B1 [KO:K12664] [EC:1.14.14.-]
128911657  cytochrome P450 26C1 [KO:K12665] [EC:1.14.14.-]
128911029  cytochrome P450 2C8-like [KO:K07413] [EC:1.14.14.1]
128911351  cytochrome P450 2C9-like [KO:K07413] [EC:1.14.14.1]
128911515  cytochrome P450 2C9-like [KO:K07413] [EC:1.14.14.1]
128911560  cytochrome P450 2C9-like [KO:K07413] [EC:1.14.14.1]
128911561  cytochrome P450 2C9-like [KO:K07413] [EC:1.14.14.1]
128917900  cytochrome P450 2C5-like [KO:K07413] [EC:1.14.14.1]
128914111  cytochrome P450 3A29-like isoform X1 [KO:K07424] [EC:1.14.14.1]
128914308  cytochrome P450 3A21-like [KO:K07424] [EC:1.14.14.1]
128913807  cytochrome P450 2W1-like isoform X1 [KO:K07423] [EC:1.14.14.-]
128914146  cytochrome P450 2W1-like [KO:K07423] [EC:1.14.14.-]
128912751  UDP-glucuronosyltransferase 1A9-like isoform X1 [KO:K00699] [EC:2.4.1.17]
128912753  UDP-glucuronosyltransferase 1A1-like [KO:K00699] [EC:2.4.1.17]
128912754  UDP-glucuronosyltransferase 1A1-like [KO:K00699] [EC:2.4.1.17]
128909737  UDP-glucuronosyltransferase 2C1-like isoform X1 [KO:K00699] [EC:2.4.1.17]
128919269  all-trans-retinol 13,14-reductase-like [KO:K09516] [EC:1.3.99.23]
128919674  RETSAT; all-trans-retinol 13,14-reductase isoform X1 [KO:K09516] [EC:1.3.99.23]
128913044  cytochrome P450 27C1 [KO:K17951] [EC:1.14.19.53]
Compound
C00376  Retinal
C00473  Retinol
C00777  Retinoate
C00778  Rhodopsin
C00899  11-cis-Retinol
C02075  Retinyl ester
C02094  beta-Carotene
C02110  11-cis-Retinal
C02588  Retinyl palmitate
C03455  11-cis-Retinyl palmitate
C05914  Bathorhodopsin
C05915  Lumirhodopsin
C05916  Metarhodopsin
C05917  Iodopsin
C11061  all-trans-Retinoyl-beta-glucuronide
C15492  all-trans-13,14-Dihydroretinol
C15493  9-cis-Retinoic acid
C16677  all-trans-4-Hydroxyretinoic acid
C16678  all-trans-4-Oxoretinoic acid
C16679  all-trans-18-Hydroxyretinoic acid
C16680  all-trans-5,6-Epoxyretinoic acid
C16681  9-cis-Retinal
C16682  9-cis-Retinol
C16683  4-Oxoretinol
C21797  all-trans-3,4-Didehydroretinol
Reference
PMID:16968212
  Authors
Travis GH, Golczak M, Moise AR, Palczewski K.
  Title
Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents.
  Journal
Annu Rev Pharmacol Toxicol 47:469-512 (2007)
DOI:10.1146/annurev.pharmtox.47.120505.105225
Reference
PMID:17618621
  Authors
Muniz A, Villazana-Espinoza ET, Hatch AL, Trevino SG, Allen DM, Tsin AT.
  Title
A novel cone visual cycle in the cone-dominated retina.
  Journal
Exp Eye Res 85:175-84 (2007)
DOI:10.1016/j.exer.2007.05.003
Reference
PMID:11093772
  Authors
Marill J, Cresteil T, Lanotte M, Chabot GG.
  Title
Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.
  Journal
Mol Pharmacol 58:1341-8 (2000)
DOI:10.1124/mol.58.6.1341
Reference
PMID:17893666
  Authors
Nezzar H, Chiambaretta F, Marceau G, Blanchon L, Faye B, Dechelotte P, Rigal D, Sapin V.
  Title
Molecular and metabolic retinoid pathways in the human ocular surface.
  Journal
Mol Vis 13:1641-50 (2007)
Reference
PMID:16688755
  Authors
Blomhoff R, Blomhoff HK.
  Title
Overview of retinoid metabolism and function.
  Journal
J Neurobiol 66:606-30 (2006)
DOI:10.1002/neu.20242
Reference
PMID:16428379
  Authors
Liden M, Eriksson U.
  Title
Understanding retinol metabolism: structure and function of retinol dehydrogenases.
  Journal
J Biol Chem 281:13001-4 (2006)
DOI:10.1074/jbc.R500027200
KO pathway
ko00830   
LinkDB

DBGET integrated database retrieval system