KEGG   PATHWAY: sanh00590
Entry
sanh00590                   Pathway                                
Name
Arachidonic acid metabolism - Sinocyclocheilus anshuiensis
Class
Metabolism; Lipid metabolism
Pathway map
sanh00590  Arachidonic acid metabolism
sanh00590

Other DBs
GO: 0019369
Organism
Sinocyclocheilus anshuiensis [GN:sanh]
Gene
107694032  uncharacterized protein LOC107694032 isoform X1 [KO:K01047] [EC:3.1.1.4]
107702679  group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
107704109  group 3 secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
107665777  group 3 secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
107674667  group 10 secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
107665940  group XIIA secretory phospholipase A2-like isoform X1 [KO:K01047] [EC:3.1.1.4]
107703381  group 10 secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
107687982  phospholipase A2, minor isoenzyme-like [KO:K01047] [EC:3.1.1.4]
107703140  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
107703141  phospholipase A2, minor isoenzyme-like [KO:K01047] [EC:3.1.1.4]
107703142  phospholipase A2, minor isoenzyme-like [KO:K01047] [EC:3.1.1.4]
107692613  group XIIA secretory phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
107687988  phospholipase A2-like [KO:K01047] [EC:3.1.1.4]
107660215  group XIIB secretory phospholipase A2-like protein isoform X1 [KO:K01047] [EC:3.1.1.4]
107672398  uncharacterized protein LOC107672398 [KO:K01047] [EC:3.1.1.4]
107698318  cytosolic phospholipase A2-like [KO:K16342] [EC:3.1.1.4]
107701849  cytosolic phospholipase A2 zeta-like isoform X1 [KO:K16342] [EC:3.1.1.4]
107701850  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
107701851  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
107701853  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
107656596  cytosolic phospholipase A2 gamma-like isoform X1 [KO:K16342] [EC:3.1.1.4]
107696149  cytosolic phospholipase A2-like isoform X1 [KO:K16342] [EC:3.1.1.4]
107693742  cytosolic phospholipase A2-like [KO:K16342] [EC:3.1.1.4]
107689769  cytosolic phospholipase A2 zeta-like [KO:K16342] [EC:3.1.1.4]
107689812  cytosolic phospholipase A2 delta-like [KO:K16342] [EC:3.1.1.4]
107677770  cytosolic phospholipase A2 [KO:K16342] [EC:3.1.1.4]
107654280  cytosolic phospholipase A2 gamma-like [KO:K16342] [EC:3.1.1.4]
107667889  85/88 kDa calcium-independent phospholipase A2-like isoform X1 [KO:K16343] [EC:3.1.1.4]
107704553  85/88 kDa calcium-independent phospholipase A2-like [KO:K16343] [EC:3.1.1.4]
107659236  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
107654820  phospholipase B1, membrane-associated-like [KO:K14621] [EC:3.1.1.4 3.1.1.5]
107680652  HRAS-like suppressor 3 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
107680588  HRAS-like suppressor 3 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
107676524  HRAS-like suppressor 3 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
107703067  HRAS-like suppressor 3 isoform X1 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
107694489  LOW QUALITY PROTEIN: retinoic acid receptor responder protein 3-like [KO:K16817] [EC:3.1.1.32 3.1.1.4]
107699776  prostaglandin G/H synthase 1-like [KO:K00509] [EC:1.14.99.1]
107672577  prostaglandin G/H synthase 1-like [KO:K00509] [EC:1.14.99.1]
107698381  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
107677761  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
107693741  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
107696154  prostaglandin G/H synthase 2-like [KO:K11987] [EC:1.14.99.1]
107691017  prostaglandin E synthase-like [KO:K15729] [EC:5.3.99.3]
107693847  prostaglandin E synthase-like [KO:K15729] [EC:5.3.99.3]
107667550  prostaglandin E synthase 2-like [KO:K05309] [EC:5.3.99.3]
107667902  prostaglandin E synthase 2 [KO:K05309] [EC:5.3.99.3]
107695820  prostaglandin E synthase 3-like [KO:K15730] [EC:5.3.99.3]
107697015  prostaglandin E synthase 3-like [KO:K15730] [EC:5.3.99.3]
107668559  prostaglandin E synthase 3-like [KO:K15730] [EC:5.3.99.3]
107673275  prostaglandin E synthase 3-like [KO:K15730] [EC:5.3.99.3]
107681174  carbonyl reductase [NADPH] 1-like [KO:K00079] [EC:1.1.1.184 1.1.1.189 1.1.1.197]
107676886  cbr1; carbonyl reductase [NADPH] 1 [KO:K00079] [EC:1.1.1.184 1.1.1.189 1.1.1.197]
107692178  carbonyl reductase [NADPH] 1-like [KO:K00079] [EC:1.1.1.184 1.1.1.189 1.1.1.197]
107702003  prostamide/prostaglandin F synthase [KO:K15717] [EC:1.11.1.20]
107654427  prostamide/prostaglandin F synthase-like [KO:K15717] [EC:1.11.1.20]
107671517  15-hydroxyprostaglandin dehydrogenase [NAD(+)]-like [KO:K00069] [EC:1.1.1.141]
107668435  15-hydroxyprostaglandin dehydrogenase [NAD(+)]-like [KO:K00069] [EC:1.1.1.141]
107685774  15-hydroxyprostaglandin dehydrogenase [NAD(+)]-like [KO:K00069] [EC:1.1.1.141]
107692995  15-hydroxyprostaglandin dehydrogenase [NAD(+)]-like [KO:K00069] [EC:1.1.1.141]
107676678  15-hydroxyprostaglandin dehydrogenase [NAD(+)]-like [KO:K00069] [EC:1.1.1.141]
107684653  thromboxane-A synthase-like [KO:K01832] [EC:5.3.99.5]
107654290  LOW QUALITY PROTEIN: lipocalin-like [KO:K01830] [EC:5.3.99.2]
107685120  lipocalin-15-like [KO:K01830] [EC:5.3.99.2]
107672532  prostaglandin-H2 D-isomerase-like isoform X1 [KO:K01830] [EC:5.3.99.2]
107665866  lipocalin-like [KO:K01830] [EC:5.3.99.2]
107686711  lipocalin-like [KO:K01830] [EC:5.3.99.2]
107658663  prostaglandin-H2 D-isomerase-like [KO:K01830] [EC:5.3.99.2]
107683250  prostaglandin-H2 D-isomerase-like [KO:K01830] [EC:5.3.99.2]
107679760  lipocalin-like [KO:K01830] [EC:5.3.99.2]
107695405  lipocalin-like [KO:K01830] [EC:5.3.99.2]
107667039  prostacyclin synthase-like [KO:K01831] [EC:5.3.99.4]
107680687  prostacyclin synthase-like [KO:K01831] [EC:5.3.99.4]
107677802  arachidonate 5-lipoxygenase-like [KO:K00461] [EC:1.13.11.34]
107684374  arachidonate 5-lipoxygenase-like [KO:K00461] [EC:1.13.11.34]
107671382  arachidonate 5-lipoxygenase-like [KO:K00461] [EC:1.13.11.34]
107690200  arachidonate 5-lipoxygenase-like isoform X1 [KO:K00461] [EC:1.13.11.34]
107678516  arachidonate 5-lipoxygenase-like [KO:K00461] [EC:1.13.11.34]
107656327  leukotriene A-4 hydrolase-like isoform X1 [KO:K01254] [EC:3.3.2.6]
107658863  leukotriene A-4 hydrolase-like [KO:K01254] [EC:3.3.2.6]
107679756  ptgr2; prostaglandin reductase 2 [KO:K13949] [EC:1.3.1.48]
107691929  prostaglandin reductase 1-like isoform X1 [KO:K13948] [EC:1.3.1.74 1.3.1.48]
107668743  prostaglandin reductase 1-like [KO:K13948] [EC:1.3.1.74 1.3.1.48]
107667453  leukotriene C4 synthase-like [KO:K00807] [EC:4.4.1.20]
107660445  leukotriene C4 synthase-like [KO:K00807] [EC:4.4.1.20]
107658589  gamma-glutamyltransferase 5-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
107703163  gamma-glutamyltransferase 5-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
107703144  gamma-glutamyltranspeptidase 1-like isoform X1 [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
107658554  gamma-glutamyltranspeptidase 1-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
107689083  gamma-glutamyltransferase 5-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
107689091  gamma-glutamyltranspeptidase 1-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
107660382  phospholipid hydroperoxide glutathione peroxidase, mitochondrial-like [KO:K05361] [EC:1.11.1.12]
107665313  cytochrome P450 2J2-like [KO:K07418] [EC:1.14.14.1 1.14.14.73 1.14.14.74 1.14.14.75]
107683164  cytochrome P450 2U1-like [KO:K07422] [EC:1.14.14.80]
107669199  arachidonate 12-lipoxygenase, 12S-type-like [KO:K00458] [EC:1.13.11.31]
107673846  hydroperoxide isomerase ALOXE3-like [KO:K18684] [EC:4.2.1.152 5.4.4.7]
107699996  hydroperoxide isomerase ALOXE3-like isoform X1 [KO:K18684] [EC:4.2.1.152 5.4.4.7]
107653762  bifunctional epoxide hydrolase 2-like isoform X1 [KO:K08726] [EC:3.3.2.10 3.1.3.76]
107692411  bifunctional epoxide hydrolase 2-like [KO:K08726] [EC:3.3.2.10 3.1.3.76]
Compound
C00157  Phosphatidylcholine
C00219  Arachidonate
C00427  Prostaglandin H2
C00584  Prostaglandin E2
C00639  Prostaglandin F2alpha
C00696  Prostaglandin D2
C00909  Leukotriene A4
C01312  Prostaglandin I2
C02165  Leukotriene B4
C02166  Leukotriene C4
C02198  Thromboxane A2
C03577  20-Hydroxyleukotriene E4
C04577  15-OxoETE
C04671  (5Z)-11alpha-Hydroxy-9,15-dioxoprostanoate
C04707  (5Z,13E)-11alpha-Hydroxy-9,15-dioxoprost-5,13-dienoate
C04742  (15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate
C04758  (5Z,13E)-9alpha-Hydroxy-11,15-dioxoprosta-5,13-dienoate
C04805  5(S)-HETE
C04822  8(R)-HPETE
C04835  (5Z,13E)-6,9alpha-Epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate
C04853  20-OH-Leukotriene B4
C05356  5(S)-HPETE
C05949  12-Keto-leukotriene B4
C05950  20-COOH-Leukotriene B4
C05951  Leukotriene D4
C05952  Leukotriene E4
C05953  Prostaglandin A2
C05954  Prostaglandin B2
C05955  Prostaglandin C2
C05956  Prostaglandin G2
C05957  Prostaglandin J2
C05958  Delta-12-Prostaglandin J2
C05959  11-epi-Prostaglandin F2alpha
C05960  15-Keto-prostaglandin F2alpha
C05961  6-Keto-prostaglandin F1alpha
C05962  6-Keto-prostaglandin E1
C05963  Thromboxane B2
C05964  11-Dehydro-thromboxane B2
C05965  12(S)-HPETE
C05966  15(S)-HPETE
C06314  Lipoxin A4
C06315  Lipoxin B4
C06462  Leukotriene F4
C13809  9,11,15-Trihydroxy-prosta-5,13-dien-1-oic acid
C14717  15-Deoxy-Delta12,14-PGJ2
C14732  5-OxoETE
C14748  20-HETE
C14749  19(S)-HETE
C14768  5,6-EET
C14769  8,9-EET
C14770  11,12-EET
C14771  14,15-EET
C14772  5,6-DHET
C14773  8,9-DHET
C14774  11,12-DHET
C14775  14,15-DHET
C14776  8(S)-HETE
C14777  12(S)-HETE
C14778  16(R)-HETE
C14779  9(S)-HETE
C14780  11(R)-HETE
C14781  15H-11,12-EETA
C14782  11,12,15-THETA
C14794  2,3-Dinor-8-iso prostaglandin F2alpha
C14795  2,3-Dinor-8-iso prostaglandin F1alpha
C14807  12-OxoETE
C14808  Hepoxilin A3
C14809  Trioxilin A3
C14810  Hepoxilin B3
C14811  Trioxilin B3
C14812  12(R)-HPETE
C14813  11H-14,15-EETA
C14814  11,14,15-THETA
C14815  5,6-Epoxytetraene
C14820  11(R)-HPETE
C14821  9(S)-HPETE
C14822  12(R)-HETE
C14823  8(S)-HPETE
C14824  8(R)-HETE
Reference
PMID:14636671
  Authors
Spector AA, Fang X, Snyder GD, Weintraub NL.
  Title
Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function.
  Journal
Prog Lipid Res 43:55-90 (2004)
DOI:10.1016/S0163-7827(03)00049-3
Reference
PMID:15292194
  Authors
Harman CA, Rieke CJ, Garavito RM, Smith WL.
  Title
Crystal structure of arachidonic acid bound to a mutant of prostaglandin endoperoxide H synthase-1 that forms predominantly 11-hydroperoxyeicosatetraenoic acid.
  Journal
J Biol Chem 279:42929-35 (2004)
DOI:10.1074/jbc.M403013200
Reference
PMID:15205388
  Authors
Poloyac SM, Tortorici MA, Przychodzin DI, Reynolds RB, Xie W, Frye RF, Zemaitis MA.
  Title
The effect of isoniazid on CYP2E1- and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney.
  Journal
Drug Metab Dispos 32:727-33 (2004)
DOI:10.1124/dmd.32.7.727
Reference
PMID:14660610
  Authors
Chuang SS, Helvig C, Taimi M, Ramshaw HA, Collop AH, Amad M, White JA, Petkovich M, Jones G, Korczak B.
  Title
CYP2U1, a novel human thymus- and brain-specific cytochrome P450, catalyzes omega- and (omega-1)-hydroxylation of fatty acids.
  Journal
J Biol Chem 279:6305-14 (2004)
DOI:10.1074/jbc.M311830200
Reference
PMID:14626496
  Authors
Sacerdoti D, Gatta A, McGiff JC.
  Title
Role of cytochrome P450-dependent arachidonic acid metabolites in liver physiology and pathophysiology.
  Journal
Prostaglandins Other Lipid Mediat 72:51-71 (2003)
DOI:10.1016/S1098-8823(03)00077-7
Reference
PMID:14622984
  Authors
Pfister SL, Spitzbarth N, Zeldin DC, Lafite P, Mansuy D, Campbell WB.
  Title
Rabbit aorta converts 15-HPETE to trihydroxyeicosatrienoic acids: potential role of cytochrome P450.
  Journal
Arch Biochem Biophys 420:142-52 (2003)
DOI:10.1016/j.abb.2003.09.026
Reference
PMID:11679404
  Authors
Fleming I.
  Title
Cytochrome p450 and vascular homeostasis.
  Journal
Circ Res 89:753-62 (2001)
DOI:10.1161/hh2101.099268
Reference
PMID:11328810
  Authors
Qu W, Bradbury JA, Tsao CC, Maronpot R, Harry GJ, Parker CE, Davis LS, Breyer MD, Waalkes MP, Falck JR, Chen J, Rosenberg RL, Zeldin DC.
  Title
Cytochrome P450 CYP2J9, a new mouse arachidonic acid omega-1 hydroxylase predominantly expressed in brain.
  Journal
J Biol Chem 276:25467-79 (2001)
DOI:10.1074/jbc.M100545200
Reference
PMID:10908295
  Authors
Tsao CC, Foley J, Coulter SJ, Maronpot R, Zeldin DC, Goldstein JA.
  Title
CYP2C40, a unique arachidonic acid 16-hydroxylase, is the major CYP2C in murine intestinal tract.
  Journal
Mol Pharmacol 58:279-87 (2000)
DOI:10.1124/mol.58.2.279
Reference
PMID:9812980
  Authors
Pfister SL, Spitzbarth N, Nithipatikom K, Edgemond WS, Falck JR, Campbell WB.
  Title
Identification of the 11,14,15- and 11,12, 15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aorta.
  Journal
J Biol Chem 273:30879-87 (1998)
DOI:10.1074/jbc.273.47.30879
Related
pathway
sanh00591  Linoleic acid metabolism
KO pathway
ko00590   
LinkDB

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