KEGG   PATHWAY: sbi00230
Entry
sbi00230                    Pathway                                
Name
Purine metabolism - Sorghum bicolor (sorghum)
Class
Metabolism; Nucleotide metabolism
Pathway map
sbi00230  Purine metabolism
sbi00230

Module
sbi_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sbi00230]
sbi_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sbi00230]
sbi_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sbi00230]
sbi_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sbi00230]
sbi_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sbi00230]
Other DBs
GO: 0006163 0042278
Organism
Sorghum bicolor (sorghum) [GN:sbi]
Gene
8057997  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
110433154  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
8067681  nudix hydrolase 2 isoform X2 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
8074182  nudix hydrolase 23, chloroplastic [KO:K18453] [EC:3.6.1.13 3.6.1.18]
8069051  nudix hydrolase 14, chloroplastic [KO:K18447] [EC:3.6.1.21]
8084835  phosphoglucomutase, chloroplastic [KO:K01835] [EC:5.4.2.2]
8063383  phosphoglucomutase, cytoplasmic 2 [KO:K01835] [EC:5.4.2.2]
8083460  ribose-phosphate pyrophosphokinase 2, chloroplastic isoform X1 [KO:K00948] [EC:2.7.6.1]
8055076  ribose-phosphate pyrophosphokinase 1, chloroplastic [KO:K00948] [EC:2.7.6.1]
8059545  ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
8058504  amidophosphoribosyltransferase, chloroplastic [KO:K00764] [EC:2.4.2.14]
8060995  amidophosphoribosyltransferase, chloroplastic [KO:K00764] [EC:2.4.2.14]
8068993  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
8057177  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
110437693  phosphoribosylamine--glycine ligase-like isoform X1 [KO:K01945] [EC:6.3.4.13]
8080300  phosphoribosylglycinamide formyltransferase, chloroplastic [KO:K00601] [EC:2.1.2.2]
8063375  probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial [KO:K01952] [EC:6.3.5.3]
8079613  probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial [KO:K01952] [EC:6.3.5.3]
8055712  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial [KO:K01933] [EC:6.3.3.1]
8068668  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial [KO:K01933] [EC:6.3.3.1]
8084329  phosphoribosylaminoimidazole carboxylase, chloroplastic isoform X1 [KO:K11808] [EC:4.1.1.21]
8063728  phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic [KO:K01923] [EC:6.3.2.6]
8082874  uncharacterized protein LOC8082874 [KO:K01756] [EC:4.3.2.2]
8071173  uncharacterized protein LOC8071173 isoform X1 [KO:K00602] [EC:2.1.2.3 3.5.4.10]
8072340  uncharacterized protein LOC8072340 isoform X3 [KO:K00602] [EC:2.1.2.3 3.5.4.10]
8074301  adenine phosphoribosyltransferase 1 [KO:K00759] [EC:2.4.2.7]
8072458  adenine phosphoribosyltransferase 4 [KO:K00759] [EC:2.4.2.7]
8075898  adenine phosphoribosyltransferase 2 [KO:K00759] [EC:2.4.2.7]
8069775  uncharacterized protein LOC8069775 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
8063690  uncharacterized protein LOC8063690 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
8064204  uncharacterized protein LOC8064204 [KO:K00760] [EC:2.4.2.8]
8079908  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
8084158  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
8068811  nucleoside diphosphate kinase 2, chloroplastic [KO:K00940] [EC:2.7.4.6]
8080696  nucleoside diphosphate kinase 1 [KO:K00940] [EC:2.7.4.6]
8058066  nucleoside diphosphate kinase 1 [KO:K00940] [EC:2.7.4.6]
110430365  nucleoside diphosphate kinase 3-like [KO:K00940] [EC:2.7.4.6]
8075671  probable apyrase 4 isoform X2 [KO:K01510] [EC:3.6.1.5]
8080757  probable apyrase 6 [KO:K01510] [EC:3.6.1.5]
8084559  probable apyrase 1 [KO:K14641] [EC:3.6.1.5]
8074461  probable apyrase 2 [KO:K14641] [EC:3.6.1.5]
8083035  probable apyrase 3 [KO:K14641] [EC:3.6.1.5]
8071608  probable apyrase 3 [KO:K14641] [EC:3.6.1.5]
8067142  probable apyrase 3 [KO:K14641] [EC:3.6.1.5]
8076917  probable apyrase 3 [KO:K14641] [EC:3.6.1.5]
8067632  LOW QUALITY PROTEIN: probable apyrase 3 [KO:K14641] [EC:3.6.1.5]
8059277  inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
110434890  xanthine dehydrogenase [KO:K00106] [EC:1.17.1.4 1.17.3.2]
8076514  uncharacterized protein LOC8076514 [KO:K01951] [EC:6.3.5.2]
110433418  guanylate kinase 2, chloroplastic/mitochondrial [KO:K00942] [EC:2.7.4.8]
110437483  LOW QUALITY PROTEIN: guanylate kinase 1-like [KO:K00942] [EC:2.7.4.8]
8084665  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
8070903  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
8060204  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
8065749  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
8058223  HD domain-containing protein 2 homolog [KO:K07023] [EC:3.1.3.89]
110435096  HD domain-containing protein 2 homolog [KO:K07023] [EC:3.1.3.89]
8060673  probable GTP diphosphokinase RSH3, chloroplastic [KO:K00951] [EC:2.7.6.5]
8080920  probable GTP diphosphokinase CRSH1, chloroplastic [KO:K00951] [EC:2.7.6.5]
110437081  probable GTP diphosphokinase RSH2, chloroplastic [KO:K00951] [EC:2.7.6.5]
8081003  probable GTP diphosphokinase RSH3, chloroplastic [KO:K00951] [EC:2.7.6.5]
8082317  putative GTP diphosphokinase RSH1, chloroplastic [KO:K00951] [EC:2.7.6.5]
8074779  phytosulfokine receptor 1 [KO:K27625] [EC:2.7.11.1 4.6.1.2]
8070309  phytosulfokine receptor 1 [KO:K27625] [EC:2.7.11.1 4.6.1.2]
8062947  adenylosuccinate synthetase 2, chloroplastic [KO:K01939] [EC:6.3.4.4]
8059802  adenylosuccinate synthetase 1, chloroplastic [KO:K01939] [EC:6.3.4.4]
8083756  probable AMP deaminase isoform X1 [KO:K01490] [EC:3.5.4.6]
8084990  probable AMP deaminase [KO:K01490] [EC:3.5.4.6]
8075936  adenosine kinase 2 [KO:K00856] [EC:2.7.1.20]
110434493  adenosine kinase 2-like [KO:K00856] [EC:2.7.1.20]
8058194  adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
8060373  adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
8074040  probable adenylate kinase 7, mitochondrial [KO:K00939] [EC:2.7.4.3]
8064360  adenylate kinase, chloroplastic [KO:K00939] [EC:2.7.4.3]
8058216  adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
8085685  probable adenylate kinase 1, chloroplastic [KO:K00939] [EC:2.7.4.3]
110436684  probable adenylate kinase 6, chloroplastic [KO:K00939] [EC:2.7.4.3]
110436757  probable adenylate kinase 5, chloroplastic isoform X1 [KO:K00939] [EC:2.7.4.3]
8057928  adenylate kinase isoenzyme 6 homolog [KO:K18532] [EC:2.7.4.3]
8061434  cancer-related nucleoside-triphosphatase homolog [KO:K06928] [EC:3.6.1.15]
8084339  ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
8074831  bifunctional bis(5'-adenosyl)-triphosphatase/adenylylsulfatase FHIT [KO:K01522] [EC:3.6.1.29]
8060484  ATP-sulfurylase 3, chloroplastic [KO:K13811] [EC:2.7.7.4 2.7.1.25]
8080261  ATP sulfurylase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
8081871  adenylyl-sulfate kinase 3 isoform X2 [KO:K00860] [EC:2.7.1.25]
8068326  adenylyl-sulfate kinase 3 isoform X2 [KO:K00860] [EC:2.7.1.25]
8055673  adenylyl-sulfate kinase 3 isoform X1 [KO:K00860] [EC:2.7.1.25]
110433901  uricase-2 [KO:K00365] [EC:1.7.3.3]
8080457  uric acid degradation bifunctional protein TTL isoform X1 [KO:K13484] [EC:3.5.2.17 4.1.1.97]
8069395  probable allantoate deiminase isoform X1 [KO:K02083] [EC:3.5.3.9]
8077471  probable (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
8076633  probable ureidoglycolate hydrolase [KO:K18151] [EC:3.5.1.116]
8054525  urease [KO:K01427] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sbi00030  Pentose phosphate pathway
sbi00220  Arginine biosynthesis
sbi00250  Alanine, aspartate and glutamate metabolism
sbi00260  Glycine, serine and threonine metabolism
sbi00340  Histidine metabolism
sbi00630  Glyoxylate and dicarboxylate metabolism
sbi00730  Thiamine metabolism
sbi00740  Riboflavin metabolism
sbi00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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