KEGG   PATHWAY: smuc00630
Entry
smuc00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Skermanella mucosa
Class
Metabolism; Carbohydrate metabolism
Pathway map
smuc00630  Glyoxylate and dicarboxylate metabolism
smuc00630

Module
smuc_M00012  Glyoxylate cycle [PATH:smuc00630]
smuc_M00621  Glycine cleavage system [PATH:smuc00630]
smuc_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:smuc00630]
Other DBs
GO: 0046487 0043648
Organism
Skermanella mucosa [GN:smuc]
Gene
JL100_001800  aceA; isocitrate lyase [KO:K01637] [EC:4.1.3.1]
JL100_029125  AMP-binding protein [KO:K01895] [EC:6.2.1.1]
JL100_029330  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
JL100_017030  acyl-CoA synthetase [KO:K01895] [EC:6.2.1.1]
JL100_004625  malate synthase G [KO:K01638] [EC:2.3.3.9]
JL100_025420  mdh; malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
JL100_014440  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
JL100_002900  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
JL100_002895  acnB; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
JL100_022735  bktB; beta-ketothiolase BktB [KO:K00626] [EC:2.3.1.9]
JL100_032160  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
JL100_034580  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
JL100_001210  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
JL100_011830  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
JL100_032155  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
JL100_011835  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
JL100_020800  MaoC family dehydratase [KO:K17865] [EC:4.2.1.55]
JL100_016570  ccrA; crotonyl-CoA carboxylase/reductase [KO:K14446] [EC:1.3.1.85]
JL100_014575  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
JL100_016565  protein meaA [KO:K14447] [EC:5.4.99.63]
JL100_016580  acyl-CoA/acyl-ACP dehydrogenase [KO:K14448] [EC:1.3.8.12]
JL100_004090  MaoC family dehydratase [KO:K14449] [EC:4.2.1.148]
JL100_003365  CoA ester lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
JL100_011455  acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha [KO:K01965] [EC:6.4.1.3]
JL100_011450  acyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
JL100_011465  scpA; methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
JL100_004275  cobalamin B12-binding domain-containing protein [KO:K01849] [EC:5.4.99.2]
JL100_004270  methylmalonyl-CoA mutase family protein [KO:K01848] [EC:5.4.99.2]
JL100_023365  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
JL100_032470  FAD-binding protein [KO:K00104] [EC:1.1.99.14]
JL100_023360  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
JL100_032465  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
JL100_023355  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
JL100_032460  glcF; glycolate oxidase subunit GlcF [KO:K11473] [EC:1.1.99.14]
JL100_026210  catalase [KO:K03781] [EC:1.11.1.6]
JL100_029310  D-glycerate dehydrogenase [KO:K00015] [EC:1.1.1.26]
JL100_024870  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
JL100_031525  D-2-hydroxyacid dehydrogenase [KO:K00018] [EC:1.1.1.29]
JL100_005055  gph; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
JL100_006220  HAD-IA family hydrolase [KO:K01091] [EC:3.1.3.18]
JL100_012190  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
JL100_025775  ribulose-bisphosphate carboxylase large subunit [KO:K01601] [EC:4.1.1.39]
JL100_025780  ribulose bisphosphate carboxylase small subunit [KO:K01602] [EC:4.1.1.39]
JL100_001905  aminotransferase class V-fold PLP-dependent enzyme [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
JL100_020965  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
JL100_014730  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
JL100_018520  glutamine synthetase beta-grasp domain-containing protein [KO:K01915] [EC:6.3.1.2]
JL100_025645  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
JL100_026645  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
JL100_025080  gcvPA; aminomethyl-transferring glycine dehydrogenase subunit GcvPA [KO:K00282] [EC:1.4.4.2]
JL100_025075  gcvPB; aminomethyl-transferring glycine dehydrogenase subunit GcvPB [KO:K00283] [EC:1.4.4.2]
JL100_025090  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
JL100_025375  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
JL100_032180  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
JL100_012260  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
JL100_025085  gcvH; glycine cleavage system protein GcvH [KO:K02437]
JL100_033455  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
JL100_033460  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
JL100_033465  glxR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
JL100_017265  glxR; 2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
JL100_017260  glycerate kinase [KO:K11529] [EC:2.7.1.165]
JL100_007235  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
JL100_010915  eda; bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
JL100_018765  formate dehydrogenase subunit delta [KO:K00126] [EC:1.17.1.9]
JL100_027235  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
JL100_033110  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
JL100_003340  formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
JL100_017095  molybdopterin-dependent oxidoreductase [KO:K00123] [EC:1.17.1.9]
JL100_018775  fdhF; formate dehydrogenase subunit alpha [KO:K00123] [EC:1.17.1.9]
JL100_033105  NAD(P)H-dependent oxidoreductase subunit E [KO:K22515] [EC:1.17.1.9]
JL100_027230  4Fe-4S dicluster domain-containing protein [KO:K00124]
JL100_003345  fdh3B; formate dehydrogenase FDH3 subunit beta [KO:K00124]
JL100_017090  fdh3B; formate dehydrogenase FDH3 subunit beta [KO:K00124]
JL100_018780  NADH-quinone oxidoreductase subunit NuoF [KO:K00124]
JL100_003350  formate dehydrogenase subunit gamma [KO:K00127]
JL100_017085  formate dehydrogenase subunit gamma [KO:K00127]
JL100_018785  formate dehydrogenase subunit gamma [KO:K00127]
JL100_012610  alpha/beta hydrolase [KO:K01432] [EC:3.5.1.9]
JL100_020205  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
JL100_017305  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
JL100_035450  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
JL100_009430  N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
JL100_034910  oxc; oxalyl-CoA decarboxylase [KO:K01577] [EC:4.1.1.8]
JL100_034915  frc; formyl-CoA transferase [KO:K07749] [EC:2.8.3.16]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
smuc00010  Glycolysis / Gluconeogenesis
smuc00020  Citrate cycle (TCA cycle)
smuc00030  Pentose phosphate pathway
smuc00053  Ascorbate and aldarate metabolism
smuc00071  Fatty acid degradation
smuc00230  Purine metabolism
smuc00250  Alanine, aspartate and glutamate metabolism
smuc00260  Glycine, serine and threonine metabolism
smuc00620  Pyruvate metabolism
smuc00710  Carbon fixation by Calvin cycle
smuc00750  Vitamin B6 metabolism
smuc00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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