KEGG   PATHWAY: phei00230
Entry
phei00230                   Pathway                                
Name
Purine metabolism - Providencia heimbachae
Class
Metabolism; Nucleotide metabolism
Pathway map
phei00230  Purine metabolism
phei00230

Module
phei_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:phei00230]
phei_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:phei00230]
phei_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:phei00230]
phei_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:phei00230]
phei_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:phei00230]
Other DBs
GO: 0006163 0042278
Organism
Providencia heimbachae [GN:phei]
Gene
NCTC12003_03119  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
NCTC12003_00110  nudE; ADP compounds hydrolase nudE [KO:K08312] [EC:3.6.1.-]
NCTC12003_00636  deoB; Phosphopentomutase [KO:K01839] [EC:5.4.2.7]
NCTC12003_02757  pgm; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
NCTC12003_02219  prs; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
NCTC12003_01538  purF; Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
NCTC12003_00418  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
NCTC12003_01797  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
NCTC12003_00998  purT; Phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
NCTC12003_01418  purL; Phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
NCTC12003_01798  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
NCTC12003_01100  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
NCTC12003_01101  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
NCTC12003_01812  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
NCTC12003_01694  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
NCTC12003_00178  pcaB; 3-carboxy-cis,cis-muconate cycloisomerase [KO:K01756] [EC:4.3.2.2]
NCTC12003_00419  purH; Bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
NCTC12003_01064  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
NCTC12003_01678  yhcR; Endonuclease YhcR precursor [KO:K01081] [EC:3.1.3.5]
NCTC12003_01082  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
NCTC12003_00953  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
NCTC12003_01072  gsk; Inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
NCTC12003_03931  punA; Purine nucleoside phosphorylase 1 [KO:K03783] [EC:2.4.2.1]
NCTC12003_00637  deoD; Purine nucleoside phosphorylase deoD-type [KO:K03784] [EC:2.4.2.1]
NCTC12003_00927  yfiH; Laccase domain protein yfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
NCTC12003_00532  rihB_1; Pyrimidine-specific ribonucleoside hydrolase rihB [KO:K25589] [EC:3.2.2.2 3.2.2.3]
NCTC12003_00606  rihB_2; Pyrimidine-specific ribonucleoside hydrolase rihB [KO:K25589] [EC:3.2.2.2 3.2.2.3]
NCTC12003_01022  hpt; Hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
NCTC12003_01833  guaB; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
NCTC12003_01451  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
NCTC12003_00657  yjjX; Non-canonical purine NTP phosphatase [KO:K01529] [EC:3.6.1.73]
NCTC12003_00862  rdgB; dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
NCTC12003_00894  gpt; Xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
NCTC12003_01834  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
NCTC12003_00800  guaD; Guanine deaminase [KO:K01487] [EC:3.5.4.3]
NCTC12003_00323  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
NCTC12003_01581  nrdA; Ribonucleoside-diphosphate reductase 1 subunit alpha [KO:K00525] [EC:1.17.4.1]
NCTC12003_03004  nrdE; Ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
NCTC12003_01580  nrdB; Ribonucleoside-diphosphate reductase 1 subunit beta [KO:K00526] [EC:1.17.4.1]
NCTC12003_03005  nrdF2; Ribonucleoside-diphosphate reductase subunit beta nrdF2 [KO:K00526] [EC:1.17.4.1]
NCTC12003_03596  nrdD; Anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
NCTC12003_01048  dgt_1; Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
NCTC12003_03568  dgt_2; Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
NCTC12003_01552  yfbR_2; 5'-nucleotidase yfbR [KO:K08722] [EC:3.1.3.89]
NCTC12003_00321  spoT; Bifunctional (p)ppGpp synthase/hydrolase SpoT [KO:K01139] [EC:2.7.6.5 3.1.7.2]
NCTC12003_01794  ppx; Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
NCTC12003_03743  gppA; Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
NCTC12003_01050  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
NCTC12003_03715  adenylate cyclase [KO:K05851] [EC:4.6.1.1]
NCTC12003_01685  putative adenylyl cyclase CyaB [KO:K05873] [EC:4.6.1.1]
NCTC12003_03673  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
NCTC12003_01957  Adenine deaminase [KO:K01488] [EC:3.5.4.4]
NCTC12003_02100  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
NCTC12003_03069  ygdH; LOG family protein ygdH [KO:K06966] [EC:3.2.2.10 3.2.2.-]
NCTC12003_00706  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor [KO:K01119] [EC:3.1.4.16 3.1.3.6]
NCTC12003_01069  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
NCTC12003_01051  mazG; Nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
NCTC12003_03118  cpdA; 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
NCTC12003_03110  apaH; Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [KO:K01525] [EC:3.6.1.41]
NCTC12003_00948  cysC; Adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
NCTC12003_00947  cysN; Sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
NCTC12003_00946  cysD; Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
NCTC12003_01494  dihydropyrimidine dehydrogenase subunit A [KO:K22879] [EC:1.14.13.113]
NCTC12003_02368  hyuC; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
NCTC12003_00225  arcC2; Carbamate kinase 2 [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
phei00030  Pentose phosphate pathway
phei00220  Arginine biosynthesis
phei00250  Alanine, aspartate and glutamate metabolism
phei00260  Glycine, serine and threonine metabolism
phei00340  Histidine metabolism
phei00630  Glyoxylate and dicarboxylate metabolism
phei00730  Thiamine metabolism
phei00740  Riboflavin metabolism
phei00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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