KEGG   PATHWAY: pon00562
Entry
pon00562                    Pathway                                
Name
Inositol phosphate metabolism - Pongo abelii (Sumatran orangutan)
Class
Metabolism; Carbohydrate metabolism
Pathway map
pon00562  Inositol phosphate metabolism
pon00562

Module
pon_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:pon00562]
pon_M00131  Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:pon00562]
pon_M00132  Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:pon00562]
Other DBs
GO: 0006020
Organism
Pongo abelii (Sumatran orangutan) [GN:pon]
Gene
100445919  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
100174495  MTM1; myotubularin [KO:K01108] [EC:3.1.3.64 3.1.3.95]
100174264  MTMR2; myotubularin-related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
100443993  MTMR1; myotubularin-related protein 1 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
100173446  MTMR3; myotubularin-related protein 3 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
100460579  MTMR4; myotubularin-related protein 4 isoform X2 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
100173546  MTMR7; myotubularin-related protein 7 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
100173697  MTMR6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
100451447  myotubularin-related protein 8 isoform X2 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
100435473  MTMR14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
100447096  PI4KA; phosphatidylinositol 4-kinase alpha isoform X1 [KO:K00888] [EC:2.7.1.67]
100456185  PI4KB; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
100439624  PI4K2A; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
100441773  phosphatidylinositol 4-kinase type 2-beta isoform X1 [KO:K13711] [EC:2.7.1.67]
100441407  phosphatidylinositol 4-kinase type 2-beta-like [KO:K13711] [EC:2.7.1.67]
100172954  SACM1L; phosphatidylinositide phosphatase SAC1 [KO:K21797] [EC:3.1.3.-]
100171873  INPP5F; phosphatidylinositide phosphatase SAC2 [KO:K21798] [EC:3.1.3.-]
100456775  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X3 [KO:K00889] [EC:2.7.1.68]
100432274  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta [KO:K00889] [EC:2.7.1.68]
100435603  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
100443776  putative PIP5K1A and PSMD4-like protein [KO:K00889] [EC:2.7.1.68]
100444466  phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1 [KO:K00889] [EC:2.7.1.68]
100439984  PIP5KL1; phosphatidylinositol 4-phosphate 5-kinase-like protein 1 [KO:K13712] [EC:2.7.1.68]
100172875  OCRL; inositol polyphosphate 5-phosphatase OCRL-1 [KO:K01099] [EC:3.1.3.36]
100462526  INPP5B; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
100445730  INPP5E; 72 kDa inositol polyphosphate 5-phosphatase [KO:K20278] [EC:3.1.3.36]
100437498  SYNJ1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
100454307  SYNJ2; synaptojanin-2 isoform X1 [KO:K20279] [EC:3.1.3.36]
100432846  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
100453779  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
103889133  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
100453085  PIK3CG; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
100171828  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
100446045  INPP5D; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
100450015  INPPL1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 [KO:K15909] [EC:3.1.3.86]
100441714  PIK3C2G; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1 [KO:K00923] [EC:2.7.1.154]
100461668  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
100457125  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
100174369  INPP4B; type II inositol 3,4-bisphosphate 4-phosphatase [KO:K01109] [EC:3.1.3.66]
100454992  INPP4A; type I inositol 3,4-bisphosphate 4-phosphatase isoform X1 [KO:K01109] [EC:3.1.3.66]
100435223  PIKFYVE; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
100462472  FIG4; polyphosphoinositide phosphatase isoform X1 [KO:K22913] [EC:3.1.3.-]
100461518  PIP4K2A; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
100459105  PIP4K2B; phosphatidylinositol 5-phosphate 4-kinase type-2 beta isoform X1 [KO:K00920] [EC:2.7.1.149]
100174032  PIP4K2C; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
100458716  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
100460060  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
100434502  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
100461961  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
100462440  PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [KO:K05857] [EC:3.1.4.11]
100443819  PLCD3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X1 [KO:K05857] [EC:3.1.4.11]
100171640  PLCD4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
100444145  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
100450941  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2 [KO:K01116] [EC:3.1.4.11]
100457650  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
100442086  PLCZ1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 isoform X1 [KO:K05861] [EC:3.1.4.11]
100459118  PLCH1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X2 [KO:K19006] [EC:3.1.4.11]
100439054  PLCH2; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 [KO:K19006] [EC:3.1.4.11]
100174641  IMPA1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
100455294  LOW QUALITY PROTEIN: inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
100452805  IMPA2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
100443337  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform X2 [KO:K00999] [EC:2.7.8.11]
100442625  ISYNA1; inositol-3-phosphate synthase 1 isoform X1 [KO:K01858] [EC:5.5.1.4]
100461697  INPP1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
100440857  INPP5A; type I inositol 1,4,5-trisphosphate 5-phosphatase isoform X2 [KO:K01106] [EC:3.1.3.56]
100457320  INPP5J; phosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform X1 [KO:K24222] [EC:3.1.3.56]
100173135  MINPP1; multiple inositol polyphosphate phosphatase 1 precursor [KO:K03103] [EC:3.1.3.62 3.1.3.80]
100460190  ITPKB; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
100448277  ITPKC; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
100453141  ITPKA; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
100448118  ITPK1; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
100462505  IPMK; inositol polyphosphate multikinase isoform X2 [KO:K00915] [EC:2.7.1.140 2.7.1.151]
100445346  IPPK; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
100171604  MIOX; inositol oxygenase [KO:K00469] [EC:1.13.99.1]
100171652  ALDH6A1; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial [KO:K00140] [EC:1.2.1.18 1.2.1.27]
100172948  TPI1; triosephosphate isomerase [KO:K01803] [EC:5.3.1.1]
Compound
C00024  Acetyl-CoA
C00092  D-Glucose 6-phosphate
C00111  Glycerone phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00137  myo-Inositol
C00191  D-Glucuronate
C00222  3-Oxopropanoate
C00558  D-Tagaturonate
C00641  1,2-Diacyl-sn-glycerol
C00691  2,4,6/3,5-Pentahydroxycyclohexanone
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C03659  D-Bornesitol
C03660  L-Bornesitol
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04287  3D-3,5/4-Trihydroxycyclohexane-1,2-dione
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04520  1D-myo-Inositol 3,4,5,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04563  D-myo-Inositol 1,2,4,5,6-pentakisphosphate
C04579  Inositol 1,2,3,5,6-pentakisphosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C06153  scyllo-Inositol
C06892  2-Deoxy-5-keto-D-gluconic acid
C06893  2-Deoxy-5-keto-D-gluconic acid 6-phosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C16737  5-Deoxy-D-glucuronate
C19794  CDP-1L-myo-inositol
C19799  Bis(1L-myo-inositol)-3,1'-phosphate 1-phosphate
C19891  1D-chiro-Inositol
C20251  1-Keto-D-chiro-inositol
C21643  3-Dehydro-scyllo-inosose
C21644  5-Dehydro-L-gluconate
Reference
PMID:14993306
  Authors
Yoshida K, Yamaguchi M, Ikeda H, Omae K, Tsurusaki K, Fujita Y
  Title
The fifth gene of the iol operon of Bacillus subtilis, iolE, encodes 2-keto-myo-inositol dehydratase.
  Journal
Microbiology 150:571-80 (2004)
DOI:10.1099/mic.0.26768-0
Reference
PMID:18310071
  Authors
Yoshida K, Yamaguchi M, Morinaga T, Kinehara M, Ikeuchi M, Ashida H, Fujita Y.
  Title
myo-Inositol catabolism in Bacillus subtilis.
  Journal
J Biol Chem 283:10415-24 (2008)
DOI:10.1074/jbc.M708043200
Related
pathway
pon00010  Glycolysis / Gluconeogenesis
pon00020  Citrate cycle (TCA cycle)
pon00040  Pentose and glucuronate interconversions
pon00564  Glycerophospholipid metabolism
KO pathway
ko00562   
LinkDB

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