KEGG   PATHWAY: psom00270
Entry
psom00270                   Pathway                                
Name
Cysteine and methionine metabolism - Papaver somniferum (opium poppy)
Description
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].
Class
Metabolism; Amino acid metabolism
Pathway map
psom00270  Cysteine and methionine metabolism
psom00270

Module
psom_M00021  Cysteine biosynthesis, serine => cysteine [PATH:psom00270]
psom_M00034  Methionine salvage pathway [PATH:psom00270]
psom_M00368  Ethylene biosynthesis, methionine => ethylene [PATH:psom00270]
Other DBs
GO: 0006534 0006555
Organism
Papaver somniferum (opium poppy) [GN:psom]
Gene
113299373  serine acetyltransferase 5-like [KO:K00640] [EC:2.3.1.30]
113319603  serine acetyltransferase 5-like [KO:K00640] [EC:2.3.1.30]
113288149  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
113289586  serine acetyltransferase 2-like isoform X1 [KO:K00640] [EC:2.3.1.30]
113295522  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
113302297  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
113295089  serine acetyltransferase 5-like [KO:K00640] [EC:2.3.1.30]
113317058  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
113318940  serine acetyltransferase 5-like [KO:K00640] [EC:2.3.1.30]
113298451  serine acetyltransferase 2-like [KO:K00640] [EC:2.3.1.30]
113358631  serine acetyltransferase 5-like [KO:K00640] [EC:2.3.1.30]
113317979  cysteine synthase-like isoform X1 [KO:K01738] [EC:2.5.1.47]
113317991  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
113318009  cysteine synthase, chloroplastic/chromoplastic-like isoform X1 [KO:K01738] [EC:2.5.1.47]
113318027  cysteine synthase, chloroplastic/chromoplastic-like isoform X1 [KO:K01738] [EC:2.5.1.47]
113318056  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
113284643  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
113284644  cysteine synthase-like isoform X1 [KO:K01738] [EC:2.5.1.47]
113347126  cysteine synthase [KO:K01738] [EC:2.5.1.47]
113333015  cysteine synthase [KO:K01738] [EC:2.5.1.47]
113317063  cysteine synthase 2 [KO:K01738] [EC:2.5.1.47]
113274742  bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial-like [KO:K13034] [EC:2.5.1.47 4.4.1.9]
113283402  cystathionine beta-lyase, chloroplastic-like [KO:K01760] [EC:4.4.1.13]
113319516  cystathionine beta-lyase, chloroplastic-like [KO:K01760] [EC:4.4.1.13]
113295043  cystathionine beta-lyase, chloroplastic-like [KO:K01760] [EC:4.4.1.13]
113293997  cystathionine beta-lyase, chloroplastic-like [KO:K01760] [EC:4.4.1.13]
113356566  cystathionine beta-lyase, chloroplastic-like [KO:K01760] [EC:4.4.1.13]
113348290  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
113347152  homocysteine S-methyltransferase 2-like isoform X1 [KO:K00547] [EC:2.1.1.10]
113357741  homocysteine S-methyltransferase 2-like isoform X1 [KO:K00547] [EC:2.1.1.10]
113350053  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
113351919  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
113308795  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 2 [KO:K00549] [EC:2.1.1.14]
113313595  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase [KO:K00549] [EC:2.1.1.14]
113320268  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
113276008  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1-like [KO:K00549] [EC:2.1.1.14]
113320503  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 2-like [KO:K00549] [EC:2.1.1.14]
113319259  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
113309574  S-adenosylmethionine synthase 3-like [KO:K00789] [EC:2.5.1.6]
113333296  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
113334825  S-adenosylmethionine synthase 5 [KO:K00789] [EC:2.5.1.6]
113346988  S-adenosylmethionine synthase 5-like [KO:K00789] [EC:2.5.1.6]
113298671  S-adenosylmethionine synthase 2-like [KO:K00789] [EC:2.5.1.6]
113304689  S-adenosylmethionine synthase 3-like [KO:K00789] [EC:2.5.1.6]
113307622  S-adenosylmethionine synthase 2-like [KO:K00789] [EC:2.5.1.6]
113338826  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
113343384  S-adenosylmethionine synthase 5-like [KO:K00789] [EC:2.5.1.6]
113336739  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
113298490  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
113297823  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
113302993  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
113278436  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
113301438  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
113360988  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
113357310  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
113299132  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
113342144  spermidine synthase-like [KO:K00797] [EC:2.5.1.16]
113276420  spermidine synthase 1 [KO:K00797] [EC:2.5.1.16]
113297918  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
113322813  spermine synthase-like isoform X1 [KO:K00797] [EC:2.5.1.16]
113338425  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
113282498  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
113358461  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
113332641  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113286440  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113286441  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113291814  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113306976  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113326007  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113301249  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113333378  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113334895  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113353597  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113353598  nicotianamine synthase-like isoform X1 [KO:K05953] [EC:2.5.1.43]
113353600  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113353604  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113358139  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113352648  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113361277  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113354002  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113354003  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113348128  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113352966  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113348893  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113359469  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113352967  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113352968  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
113290211  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2-like [KO:K01244] [EC:3.2.2.16]
113330136  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2-like isoform X1 [KO:K01244] [EC:3.2.2.16]
113288860  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2-like [KO:K01244] [EC:3.2.2.16]
113286047  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2-like isoform X1 [KO:K01244] [EC:3.2.2.16]
113293129  methylthioribose kinase 1-like [KO:K00899] [EC:2.7.1.100]
113289176  methylthioribose kinase 1-like [KO:K00899] [EC:2.7.1.100]
113337170  methylthioribose-1-phosphate isomerase-like [KO:K08963] [EC:5.3.1.23]
113328190  methylthioribose-1-phosphate isomerase-like [KO:K08963] [EC:5.3.1.23]
113287615  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
113353628  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
113318666  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
113337495  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
113338127  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
113304021  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1-like isoform X1 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
113325428  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
113338077  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
113356220  uncharacterized protein LOC113356220 [KO:K23977] [EC:2.6.1.117]
113306877  uncharacterized protein LOC113306877 [KO:K23977] [EC:2.6.1.117]
113301200  uncharacterized protein LOC113301200 [KO:K23977] [EC:2.6.1.117]
113361276  uncharacterized protein LOC113361276 [KO:K23977] [EC:2.6.1.117]
113318550  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113334119  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113335775  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113287557  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113341707  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113335631  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113341807  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113352867  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113353418  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113348796  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113350549  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113308110  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
113303656  aromatic aminotransferase ISS1-like [KO:K00837] [EC:2.6.1.-]
113299695  aromatic aminotransferase ISS1-like [KO:K00837] [EC:2.6.1.-]
113338109  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
113302624  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
113303940  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
113301795  DNA (cytosine-5)-methyltransferase CMT2-like [KO:K00558] [EC:2.1.1.37]
113312945  putative DNA (cytosine-5)-methyltransferase CMT1 [KO:K00558] [EC:2.1.1.37]
113323820  putative DNA (cytosine-5)-methyltransferase CMT1 [KO:K00558] [EC:2.1.1.37]
113323831  DNA (cytosine-5)-methyltransferase CMT3-like [KO:K00558] [EC:2.1.1.37]
113326971  DNA (cytosine-5)-methyltransferase CMT3-like isoform X1 [KO:K00558] [EC:2.1.1.37]
113331719  DNA (cytosine-5)-methyltransferase 1B-like [KO:K00558] [EC:2.1.1.37]
113339266  putative DNA (cytosine-5)-methyltransferase CMT1 [KO:K00558] [EC:2.1.1.37]
113339586  DNA (cytosine-5)-methyltransferase CMT3-like [KO:K00558] [EC:2.1.1.37]
113320409  DNA (cytosine-5)-methyltransferase CMT3-like [KO:K00558] [EC:2.1.1.37]
113294748  DNA (cytosine-5)-methyltransferase CMT2-like [KO:K00558] [EC:2.1.1.37]
113340063  DNA (cytosine-5)-methyltransferase CMT3-like isoform X1 [KO:K00558] [EC:2.1.1.37]
113320534  DNA (cytosine-5)-methyltransferase CMT3-like isoform X1 [KO:K00558] [EC:2.1.1.37]
113345878  DNA (cytosine-5)-methyltransferase 1-like [KO:K00558] [EC:2.1.1.37]
113358644  DNA (cytosine-5)-methyltransferase CMT3-like [KO:K00558] [EC:2.1.1.37]
113347389  DNA (cytosine-5)-methyltransferase 1B-like [KO:K00558] [EC:2.1.1.37]
113301782  uncharacterized protein LOC113301782 isoform X1 [KO:K17398] [EC:2.1.1.37]
113282884  adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
113296659  adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
113299438  adenosylhomocysteinase 1 [KO:K01251] [EC:3.13.2.1]
113302735  adenosylhomocysteinase 1-like [KO:K01251] [EC:3.13.2.1]
113299227  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
113358382  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
113319212  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113293988  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113293991  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113328949  1-aminocyclopropane-1-carboxylate synthase 8-like [KO:K01762] [EC:4.4.1.14]
113316306  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113316308  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113319394  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113300486  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113278032  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
113300521  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113319170  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113300612  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113351239  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113354154  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113354155  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113353425  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113361394  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
113347971  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113354097  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
113315055  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
113295123  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
113335816  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
113288051  1-aminocyclopropane-1-carboxylate oxidase 3-like [KO:K05933] [EC:1.14.17.4]
113303747  1-aminocyclopropane-1-carboxylate oxidase 3-like [KO:K05933] [EC:1.14.17.4]
113318228  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
113348538  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
113281164  aspartokinase 2, chloroplastic-like isoform X1 [KO:K00928] [EC:2.7.2.4]
113271586  aspartokinase 2, chloroplastic-like isoform X1 [KO:K00928] [EC:2.7.2.4]
113283419  bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic-like isoform X1 [KO:K12524] [EC:2.7.2.4 1.1.1.3]
113356609  bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic-like isoform X1 [KO:K12524] [EC:2.7.2.4 1.1.1.3]
113336911  uncharacterized protein LOC113336911 [KO:K00133] [EC:1.2.1.11]
113335221  LOW QUALITY PROTEIN: uncharacterized protein LOC113335221 [KO:K00133] [EC:1.2.1.11]
113286742  uncharacterized protein LOC113286742 [KO:K00133] [EC:1.2.1.11]
113360191  bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic-like [KO:K00003] [EC:1.1.1.3]
113300382  cystathionine gamma-synthase 1, chloroplastic-like [KO:K01739] [EC:2.5.1.48]
113318095  cystathionine gamma-synthase 1, chloroplastic-like [KO:K01739] [EC:2.5.1.48]
113283407  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
113285924  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
113286720  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
113356601  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
113331955  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
113283771  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like isoform X1 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
113357789  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
113283164  glutamate--cysteine ligase, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
113296928  glutamate--cysteine ligase, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
113315065  glutathione synthetase, chloroplastic-like isoform X1 [KO:K21456] [EC:6.3.2.3]
113350147  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
113303925  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
113338059  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
113348271  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
113349091  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
113302191  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
113297005  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
113282685  aspartate aminotransferase, chloroplastic-like [KO:K00811] [EC:2.6.1.1]
113355938  aspartate aminotransferase, chloroplastic-like [KO:K00811] [EC:2.6.1.1]
113280859  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
113289972  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
113302402  L-lactate dehydrogenase B [KO:K00016] [EC:1.1.1.27]
113298331  putative D-cysteine desulfhydrase 1, mitochondrial [KO:K05396] [EC:4.4.1.15]
113274066  D-cysteine desulfhydrase 2, mitochondrial-like [KO:K05396] [EC:4.4.1.15]
113303172  bifunctional D-cysteine desulfhydrase/1-aminocyclopropane-1-carboxylate deaminase, mitochondrial-like [KO:K05396] [EC:4.4.1.15]
113350229  D-cysteine desulfhydrase 2, mitochondrial-like [KO:K05396] [EC:4.4.1.15]
113347054  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
113333345  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
113334886  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
113358019  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
113317978  malate dehydrogenase-like [KO:K00025] [EC:1.1.1.37]
113297221  malate dehydrogenase, cytoplasmic-like isoform X1 [KO:K00025] [EC:1.1.1.37]
113302441  malate dehydrogenase, cytoplasmic-like isoform X1 [KO:K00025] [EC:1.1.1.37]
113322485  malate dehydrogenase-like [KO:K00025] [EC:1.1.1.37]
113313205  malate dehydrogenase-like isoform X1 [KO:K00025] [EC:1.1.1.37]
113349930  malate dehydrogenase [KO:K00025] [EC:1.1.1.37]
113297073  malate dehydrogenase 1, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
113331979  malate dehydrogenase, glyoxysomal [KO:K00026] [EC:1.1.1.37]
113334105  malate dehydrogenase, chloroplastic-like isoform X1 [KO:K00026] [EC:1.1.1.37]
113302262  malate dehydrogenase 1, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
113317930  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
113347368  malate dehydrogenase, glyoxysomal-like isoform X1 [KO:K00026] [EC:1.1.1.37]
113347395  malate dehydrogenase, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
113321748  probable S-sulfocysteine synthase, chloroplastic [KO:K22846] [EC:2.5.1.144]
113310566  probable S-sulfocysteine synthase, chloroplastic [KO:K22846] [EC:2.5.1.144]
113346715  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
113297739  D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
113301320  D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
113356879  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
113298868  phosphoserine aminotransferase 2, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
113313445  phosphoserine aminotransferase 2, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
Compound
C00019  S-Adenosyl-L-methionine
C00021  S-Adenosyl-L-homocysteine
C00022  Pyruvate
C00041  L-Alanine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00065  L-Serine
C00073  L-Methionine
C00094  Sulfite
C00097  L-Cysteine
C00109  2-Oxobutanoate
C00155  L-Homocysteine
C00170  5'-Methylthioadenosine
C00197  3-Phospho-D-glycerate
C00263  L-Homoserine
C00283  Hydrogen sulfide
C00409  Methanethiol
C00441  L-Aspartate 4-semialdehyde
C00491  L-Cystine
C00506  L-Cysteate
C00606  3-Sulfino-L-alanine
C00793  D-Cysteine
C00957  Mercaptopyruvate
C00979  O-Acetyl-L-serine
C01005  O-Phospho-L-serine
C01077  O-Acetyl-L-homoserine
C01118  O-Succinyl-L-homoserine
C01137  S-Adenosylmethioninamine
C01180  4-Methylthio-2-oxobutanoic acid
C01234  1-Aminocyclopropane-1-carboxylate
C01817  L-Homocystine
C01962  Thiocysteine
C02218  Dehydroalanine
C02291  L-Cystathionine
C02356  (S)-2-Aminobutanoate
C02989  L-Methionine S-oxide
C03082  4-Phospho-L-aspartate
C03089  5-Methylthio-D-ribose
C03145  N-Formylmethionine
C03232  3-Phosphonooxypyruvate
C03431  S-Inosyl-L-homocysteine
C03539  S-Ribosyl-L-homocysteine
C04188  S-Methyl-5-thio-D-ribose 1-phosphate
C04582  S-Methyl-5-thio-D-ribulose 1-phosphate
C05324  Nicotianamine
C05524  Aminoacyl-L-methionine
C05526  S-Glutathionyl-L-cysteine
C05527  3-Sulfinylpyruvate
C05528  3-Sulfopyruvate
C05823  3-Mercaptolactate
C05824  S-Sulfo-L-cysteine
C06547  Ethylene
C08276  3-(Methylthio)propanoate
C09306  Sulfur dioxide
C11437  1-Deoxy-D-xylulose 5-phosphate
C11481  HSO3-
C11499  (S)-3-Sulfolactate
C11537  (2R)-3-Sulfolactate
C15606  1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one
C15650  2,3-Diketo-5-methylthiopentyl-1-phosphate
C15651  2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate
C18049  N-Acyl-L-homoserine lactone
C19787  5'-S-Methyl-5'-thioinosine
C21015  gamma-L-Glutamyl-L-2-aminobutyrate
C21016  Ophthalmate
C22359  S-Methyl-1-thio-D-xylulose 5-phosphate
Reference
  Authors
Sekowska A, Denervaud V, Ashida H, Michoud K, Haas D, Yokota A, Danchin A
  Title
Bacterial variations on the methionine salvage pathway.
  Journal
BMC Microbiol 4:9 (2004)
DOI:10.1186/1471-2180-4-9
Reference
  Authors
Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A.
  Title
A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  Journal
Science 302:286-90 (2003)
DOI:10.1126/science.1086997
Reference
  Authors
Sekowska A, Danchin A.
  Title
The methionine salvage pathway in Bacillus subtilis.
  Journal
BMC Microbiol 2:8 (2002)
DOI:10.1186/1471-2180-2-8
Reference
  Authors
Berger BJ, English S, Chan G, Knodel MH.
  Title
Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis.
  Journal
J Bacteriol 185:2418-31 (2003)
DOI:10.1128/JB.185.8.2418-2431.2003
Reference
  Authors
Goyer A, Collakova E, Shachar-Hill Y, Hanson AD
  Title
Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway.
  Journal
Plant Cell Physiol 48:232-42 (2007)
DOI:10.1093/pcp/pcl055
Reference
  Authors
Rebeille F, Jabrin S, Bligny R, Loizeau K, Gambonnet B, Van Wilder V, Douce R, Ravanel S
  Title
Methionine catabolism in Arabidopsis cells is initiated by a gamma-cleavage process and leads to S-methylcysteine and isoleucine syntheses.
  Journal
Proc Natl Acad Sci U S A 103:15687-92 (2006)
DOI:10.1073/pnas.0606195103
Reference
  Authors
Pirkov I, Norbeck J, Gustafsson L, Albers E
  Title
A complete inventory of all enzymes in the eukaryotic methionine salvage pathway.
  Journal
FEBS J 275:4111-20 (2008)
DOI:10.1111/j.1742-4658.2008.06552.x
Reference
  Authors
Ashida H, Saito Y, Kojima C, Yokota A
  Title
Enzymatic characterization of 5-methylthioribulose-1-phosphate dehydratase of the methionine salvage pathway in Bacillus subtilis.
  Journal
Biosci Biotechnol Biochem 72:959-67 (2008)
DOI:10.1271/bbb.70651
Reference
  Authors
Kitabatake M, So MW, Tumbula DL, Soll D
  Title
Cysteine biosynthesis pathway in the archaeon Methanosarcina barkeri encoded by acquired bacterial genes?
  Journal
J Bacteriol 182:143-5 (2000)
DOI:10.1128/JB.182.1.143-145.2000
Reference
  Authors
Mino K, Ishikawa K
  Title
Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
  Journal
J Bacteriol 185:2277-84 (2003)
DOI:10.1128/JB.185.7.2277-2284.2003
Reference
  Authors
Tanabe S
  Title
Development of assay methods for endogenous inorganic sulfur compounds and sulfurtransferases and evaluation of the physiological functions of bound sulfur.
  Journal
Yakugaku Zasshi 128:881-900 (2008)
DOI:10.1248/yakushi.128.881
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
  Authors
Gutierrez JA, Crowder T, Rinaldo-Matthis A, Ho MC, Almo SC, Schramm VL
  Title
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
  Journal
Nat Chem Biol 5:251-7 (2009)
DOI:10.1038/nchembio.153
Related
pathway
psom00010  Glycolysis / Gluconeogenesis
psom00250  Alanine, aspartate and glutamate metabolism
psom00260  Glycine, serine and threonine metabolism
psom00290  Valine, leucine and isoleucine biosynthesis
psom00430  Taurine and hypotaurine metabolism
psom00480  Glutathione metabolism
psom00620  Pyruvate metabolism
psom00640  Propanoate metabolism
psom00770  Pantothenate and CoA biosynthesis
psom00900  Terpenoid backbone biosynthesis
psom00920  Sulfur metabolism
KO pathway
ko00270   
LinkDB

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