KEGG   PATHWAY: sfd00230
Entry
sfd00230                    Pathway                                
Name
Purine metabolism - Sinorhizobium fredii USDA 257
Class
Metabolism; Nucleotide metabolism
Pathway map
sfd00230  Purine metabolism
sfd00230

Module
sfd_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sfd00230]
sfd_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sfd00230]
sfd_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sfd00230]
sfd_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sfd00230]
sfd_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:sfd00230]
sfd_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:sfd00230]
Other DBs
GO: 0006163 0042278
Organism
Sinorhizobium fredii USDA 257 [GN:sfd]
Gene
USDA257_c00090  [KO:K01519] [EC:3.6.1.66]
USDA257_c00950  cpdA; cpdA: 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
USDA257_c01000  cya11; adenylate cyclase 1 [KO:K01768] [EC:4.6.1.1]
USDA257_c04120  cya31; putative adenylate cyclase 3 [KO:K01768] [EC:4.6.1.1]
USDA257_c04700  gppA; guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
USDA257_c04750  guaB; inosine-5'-monophosphate dehydrogenase GuaB [KO:K00088] [EC:1.1.1.205]
USDA257_c05710  purD; phosphoribosylamine--glycine ligase PurD [KO:K01945] [EC:6.3.4.13]
USDA257_c06680  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
USDA257_c06690  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
USDA257_c07740  amn; AMP nucleosidase Amn [KO:K01241] [EC:3.2.2.4]
USDA257_c07950  rsh; GTP pyrophosphokinase Rsh [KO:K01139] [EC:2.7.6.5 3.1.7.2]
USDA257_c08250  [KO:K06952] [EC:3.1.3.89]
USDA257_c08490  purF; amidophosphoribosyltransferase PurF [KO:K00764] [EC:2.4.2.14]
USDA257_c08700  gmk; guanylate kinase Gmk [KO:K00942] [EC:2.7.4.8]
USDA257_c08860  ndk; nucleoside diphosphate kinase Ndk [KO:K00940] [EC:2.7.4.6]
USDA257_c09030  purN; phosphoribosylglycinamide formyltransferase PurN [KO:K11175] [EC:2.1.2.2]
USDA257_c09040  purM; phosphoribosylformylglycinamidine cyclo-ligase PurM [KO:K01933] [EC:6.3.3.1]
USDA257_c09080  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
USDA257_c09100  cya1; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
USDA257_c09780  pucL; uric acid degradation bifunctional protein PucL [KO:K16842] [EC:3.5.2.5]
USDA257_c09790  [KO:K07127] [EC:3.5.2.17]
USDA257_c09800  xdhB; xanthine dehydrogenase FAD-binding subunit XdhB [KO:K13481] [EC:1.17.1.4]
USDA257_c09810  hcrA1; 4-hydroxybenzoyl-CoA reductase subunit alpha [KO:K13482] [EC:1.17.1.4]
USDA257_c09860  guaD1; guanine deaminase GuaD [KO:K01487] [EC:3.5.4.3]
USDA257_c09920  hyuE1; hydantoin racemase HyuE [KO:K16841] [EC:5.1.99.3]
USDA257_c11080  algC; phosphomannomutase/phosphoglucomutase AlgC [KO:K15778] [EC:5.4.2.8 5.4.2.2]
USDA257_c11870  [KO:K01768] [EC:4.6.1.1]
USDA257_c13580  cya34; putative adenylate cyclase 3 [KO:K01768] [EC:4.6.1.1]
USDA257_c15070  allA1; ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
USDA257_c15150  ylbA; uncharacterized protein YlbA [KO:K14977] [EC:3.5.3.26]
USDA257_c15860  cyaA1; adenylate cyclase 1 [KO:K01768] [EC:4.6.1.1]
USDA257_c19960  [KO:K01768] [EC:4.6.1.1]
USDA257_c20180  cyaA2; adenylate cyclase 1 [KO:K01768] [EC:4.6.1.1]
USDA257_c22450  cya3; putative adenylate cyclase [KO:K01768] [EC:4.6.1.1]
USDA257_c22460  yagR1; putative xanthine dehydrogenase YagR molybdenum-binding subunit YagR [KO:K11177] [EC:1.17.1.4]
USDA257_c22470  yagS1; putative xanthine dehydrogenase YagS FAD-binding subunit YagS [KO:K11178] [EC:1.17.1.4]
USDA257_c22480  yagT1; putative xanthine dehydrogenase yagT iron-sulfur-binding subunit YagT [KO:K13483]
USDA257_c23500  cya12; adenylate cyclase 1 [KO:K01768] [EC:4.6.1.1]
USDA257_c23570  cya4; adenylate cyclase Cya [KO:K01768] [EC:4.6.1.1]
USDA257_c23770  cya5; putative adenylate cyclase [KO:K01768] [EC:4.6.1.1]
USDA257_c26250  [KO:K01768] [EC:4.6.1.1]
USDA257_c27240  cya6; putative adenylate cyclase [KO:K01768] [EC:4.6.1.1]
USDA257_c27860  cya7; putative adenylate cyclase [KO:K01768] [EC:4.6.1.1]
USDA257_c28380  cya8; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
USDA257_c30090  cyaA3; adenylate cyclase 1 [KO:K01768] [EC:4.6.1.1]
USDA257_c31890  nodP; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
USDA257_c31900  nodQ; bifunctional enzyme NodQ [KO:K00955] [EC:2.7.7.4 2.7.1.25]
USDA257_c32430  [KO:K01768] [EC:4.6.1.1]
USDA257_c34110  adk; adenylate kinase Adk [KO:K00939] [EC:2.7.4.3]
USDA257_c35030  mazG; nucleoside triphosphate pyrophosphohydrolase MazG [KO:K04765] [EC:3.6.1.9]
USDA257_c35610  [KO:K01129] [EC:3.1.5.1]
USDA257_c35720  surE; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
USDA257_c36940  gpt; xanthine phosphoribosyltransferase Gpt [KO:K00769] [EC:2.4.2.22]
USDA257_c37050  yfkN1; trifunctional nucleotide phosphoesterase protein YfkN [KO:K01119] [EC:3.1.4.16 3.1.3.6]
USDA257_c37770  purB; adenylosuccinate lyase PurB [KO:K01756] [EC:4.3.2.2]
USDA257_c39870  nrdJ; vitamin B12-dependent ribonucleotide reductase NrdJ [KO:K00525] [EC:1.17.4.1]
USDA257_c40460  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase PurC [KO:K01923] [EC:6.3.2.6]
USDA257_c40470  purS; phosphoribosylformylglycinamidine synthase PurS [KO:K23264]
USDA257_c40480  purQ; phosphoribosylformylglycinamidine synthase 1 [KO:K23265]
USDA257_c40520  purL; phosphoribosylformylglycinamidine synthase 2 [KO:K23269]
USDA257_c42360  cya10; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
USDA257_c44630  hyuE2; hydantoin racemase HyuE [KO:K16841] [EC:5.1.99.3]
USDA257_c46740  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
USDA257_c46780  prs; ribose-phosphate pyrophosphokinase Prs [KO:K00948] [EC:2.7.6.1]
USDA257_c46920  apt; adenine phosphoribosyltransferase Apt [KO:K00759] [EC:2.4.2.7]
USDA257_c47350  ade; adenine deaminase Ade [KO:K01486] [EC:3.5.4.2]
USDA257_c47480  hcrC; 4-hydroxybenzoyl-CoA reductase subunit gamma [KO:K13481] [EC:1.17.1.4]
USDA257_c47490  xdhA; xanthine dehydrogenase molybdenum-binding subunit XdhA [KO:K13482] [EC:1.17.1.4]
USDA257_c47520  guaD2; guanine deaminase GuaD [KO:K01487] [EC:3.5.4.3]
USDA257_c47540  [KO:K07127] [EC:3.5.2.17]
USDA257_c47550  allA2; ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
USDA257_c47560  [KO:K13485] [EC:4.1.1.97]
USDA257_c47570  [KO:K16842] [EC:3.5.2.5]
USDA257_c48580  [KO:K01768] [EC:4.6.1.1]
USDA257_c49300  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
USDA257_c49330  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
USDA257_c49350  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
USDA257_c50610  hpt; hypoxanthine-guanine phosphoribosyltransferase Hpt [KO:K00760] [EC:2.4.2.8]
USDA257_c51610  yagT2; putative xanthine dehydrogenase yagT iron-sulfur-binding subunit YagT [KO:K13483]
USDA257_c51620  yagS2; putative xanthine dehydrogenase YagS FAD-binding subunit YagS [KO:K11178] [EC:1.17.1.4]
USDA257_c51630  yagR2; putative xanthine dehydrogenase YagR molybdenum-binding subunit YagR [KO:K11177] [EC:1.17.1.4]
USDA257_c51880  purA; adenylosuccinate synthetase PurA [KO:K01939] [EC:6.3.4.4]
USDA257_c52200  ymdB; uncharacterized protein YmdB [KO:K09769] [EC:3.1.4.16]
USDA257_c52330  cya38; putative adenylate cyclase 3 [KO:K01768] [EC:4.6.1.1]
USDA257_c52510  purE; N5-carboxyaminoimidazole ribonucleotide mutase PurE [KO:K01588] [EC:5.4.99.18]
USDA257_c52520  purK; N5-carboxyaminoimidazole ribonucleotide synthase PurK [KO:K01589] [EC:6.3.4.18]
USDA257_c52710  yfkN2; trifunctional nucleotide phosphoesterase protein YfkN [KO:K11751] [EC:3.1.3.5 3.6.1.45]
USDA257_c53150  pgm; phosphoglucomutase Pgm [KO:K01835] [EC:5.4.2.2]
USDA257_c53260  cyaG; adenylate/guanylate cyclase CyaG [KO:K01768] [EC:4.6.1.1]
USDA257_c53510  [KO:K01768] [EC:4.6.1.1]
USDA257_c55990  [KO:K01951] [EC:6.3.5.2]
USDA257_c56110  cya39; putative adenylate cyclase 3 [KO:K01768] [EC:4.6.1.1]
USDA257_c56650  [KO:K03651] [EC:3.1.4.53]
USDA257_c58370  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
USDA257_c59470  cya13; adenylate cyclase Cya [KO:K01768] [EC:4.6.1.1]
USDA257_c59560  punA; purine nucleoside phosphorylase 1 [KO:K03783] [EC:2.4.2.1]
USDA257_c59600  [KO:K01488] [EC:3.5.4.4]
USDA257_c59610  deoB; phosphopentomutase DeoB [KO:K01839] [EC:5.4.2.7]
USDA257_c61030  [KO:K01768] [EC:4.6.1.1]
USDA257_c61600  guaA2; GMP synthase [KO:K01951] [EC:6.3.5.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sfd00030  Pentose phosphate pathway
sfd00220  Arginine biosynthesis
sfd00250  Alanine, aspartate and glutamate metabolism
sfd00260  Glycine, serine and threonine metabolism
sfd00340  Histidine metabolism
sfd00630  Glyoxylate and dicarboxylate metabolism
sfd00730  Thiamine metabolism
sfd00740  Riboflavin metabolism
sfd00790  Folate biosynthesis
KO pathway
ko00230   

DBGET integrated database retrieval system