KEGG   PATHWAY: vsr00230
Entry
vsr00230                    Pathway                                
Name
Purine metabolism - Vibrio spartinae
Class
Metabolism; Nucleotide metabolism
Pathway map
vsr00230  Purine metabolism
vsr00230

Module
vsr_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:vsr00230]
vsr_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:vsr00230]
vsr_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:vsr00230]
vsr_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:vsr00230]
vsr_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:vsr00230]
vsr_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:vsr00230]
vsr_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:vsr00230]
Other DBs
GO: 0006163 0042278
Organism
Vibrio spartinae [GN:vsr]
Gene
Vspart_00057  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
Vspart_00058  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
Vspart_00227  spoT; Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Vspart_00229  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
Vspart_00343  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
Vspart_00380  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor [KO:K01119] [EC:3.1.4.16 3.1.3.6]
Vspart_00382  cysD; Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
Vspart_00383  cysN; Sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
Vspart_00385  cysC; Adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
Vspart_00520  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
Vspart_00521  mazG; Nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
Vspart_00533  nudF_1; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Vspart_00535  cpdA_1; 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
Vspart_00563  hpt; Hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Vspart_00697  [KO:K01529]
Vspart_00704  yfiH; Laccase domain protein YfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Vspart_00726  ppx; Exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Vspart_00754  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Vspart_00764  guaB_2; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Vspart_00765  guaA; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
Vspart_00800  dgt; Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
Vspart_00875  cpdA_2; 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
Vspart_00906  purL; Phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
Vspart_00937  ygdH; LOG family protein YgdH [KO:K06966] [EC:3.2.2.10 3.2.2.-]
Vspart_00992  adk; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
Vspart_01004  purF; Amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Vspart_01066  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Vspart_01089  yfbR; 5'-nucleotidase YfbR [KO:K08722] [EC:3.1.3.89]
Vspart_01110  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Vspart_01457  cpdA_3; 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
Vspart_01524  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Vspart_01609  nrdB; Ribonucleoside-diphosphate reductase 1 subunit beta [KO:K00526] [EC:1.17.4.1]
Vspart_01610  nrdA; Ribonucleoside-diphosphate reductase 1 subunit alpha [KO:K00525] [EC:1.17.4.1]
Vspart_01958  [KO:K16841] [EC:5.1.99.3]
Vspart_02020  purT_1; Phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
Vspart_02085  gsk; Inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
Vspart_02088  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Vspart_02358  pgm; Phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
Vspart_02424  yfkN; Trifunctional nucleotide phosphoesterase protein YfkN precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
Vspart_02433  prs; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Vspart_02484  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Vspart_02485  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Vspart_02535  gpt; Xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
Vspart_02572  [KO:K21053] [EC:3.5.4.2]
Vspart_02584  deoD1; Purine nucleoside phosphorylase DeoD-type 1 [KO:K03784] [EC:2.4.2.1]
Vspart_02715  hpxO_2; FAD-dependent urate hydroxylase [KO:K16839] [EC:1.14.13.113]
Vspart_02720  surE; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Vspart_02887  rdgB; dITP/XTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
Vspart_02909  apaH; Bis(5'-nucleosyl)-tetraphosphatase [symmetrical] [KO:K01525] [EC:3.6.1.41]
Vspart_03124  gppA; Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Vspart_03147  purH; Bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Vspart_03148  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Vspart_03156  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
Vspart_03272  cyaA; Adenylate cyclase [KO:K05851] [EC:4.6.1.1]
Vspart_03546  [KO:K01081] [EC:3.1.3.5]
Vspart_03855  nudF_2; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Vspart_03937  nrdD; Anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
Vspart_03947  guaD; Guanine deaminase [KO:K01487] [EC:3.5.4.3]
Vspart_03948  hiuH; 5-hydroxyisourate hydrolase precursor [KO:K07127] [EC:3.5.2.17]
Vspart_03949  uao; Uric acid degradation bifunctional protein [KO:K16840] [EC:4.1.1.97]
Vspart_03951  xdhA; Xanthine dehydrogenase molybdenum-binding subunit [KO:K13482] [EC:1.17.1.4]
Vspart_03952  hcrC; 4-hydroxybenzoyl-CoA reductase subunit gamma [KO:K13481] [EC:1.17.1.4]
Vspart_04002  [KO:K01081] [EC:3.1.3.5]
Vspart_04148  amaB; N-carbamoyl-L-amino acid hydrolase [KO:K02083] [EC:3.5.3.9]
Vspart_04149  pucG_2; Purine catabolism protein PucG [KO:K00839] [EC:2.6.1.112]
Vspart_04150  ywrD; Putative gamma-glutamyltransferase YwrD [KO:K22602] [EC:3.5.1.126]
Vspart_04162  [KO:K16842] [EC:3.5.2.5]
Vspart_04336  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
vsr00030  Pentose phosphate pathway
vsr00220  Arginine biosynthesis
vsr00250  Alanine, aspartate and glutamate metabolism
vsr00260  Glycine, serine and threonine metabolism
vsr00340  Histidine metabolism
vsr00630  Glyoxylate and dicarboxylate metabolism
vsr00730  Thiamine metabolism
vsr00740  Riboflavin metabolism
vsr00790  Folate biosynthesis
KO pathway
ko00230   

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