KEGG   PATHWAY: xhe00562
Entry
xhe00562                    Pathway                                
Name
Inositol phosphate metabolism - Xiphophorus hellerii (green swordtail)
Class
Metabolism; Carbohydrate metabolism
Pathway map
xhe00562  Inositol phosphate metabolism
xhe00562

Module
xhe_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:xhe00562]
xhe_M00131  Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:xhe00562]
xhe_M00132  Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:xhe00562]
Other DBs
GO: 0006020
Organism
Xiphophorus hellerii (green swordtail) [GN:xhe]
Gene
116707666  inpp5k; inositol polyphosphate 5-phosphatase K isoform X1 [KO:K24222]
116707698  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
116707717  miox; inositol oxygenase [KO:K00469] [EC:1.13.99.1]
116707759  plch1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X1 [KO:K19006] [EC:3.1.4.11]
116707799  inppl1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 [KO:K15909] [EC:3.1.3.86]
116708418  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
116708435  plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
116708711  itpk1; inositol-tetrakisphosphate 1-kinase isoform X1 [KO:K00913] [EC:2.7.1.159 2.7.1.134]
116708822  itpka; inositol-trisphosphate 3-kinase A isoform X1 [KO:K00911] [EC:2.7.1.127]
116709301  aldh6a1; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial [KO:K00140] [EC:1.2.1.18 1.2.1.27]
116709432  isyna1; inositol-3-phosphate synthase 1 [KO:K01858] [EC:5.5.1.4]
116709603  [KO:K00911] [EC:2.7.1.127]
116709820  [KO:K00923] [EC:2.7.1.154]
116710011  [KO:K07756] [EC:2.7.4.21]
116710169  [KO:K00920] [EC:2.7.1.149]
116710231  mtmr14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
116710269  [KO:K07756] [EC:2.7.4.21]
116710324  [KO:K00923] [EC:2.7.1.154]
116710601  [KO:K07756] [EC:2.7.4.21]
116710757  ippk; inositol-pentakisphosphate 2-kinase isoform X1 [KO:K10572] [EC:2.7.1.158]
116710782  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
116710859  [KO:K07756] [EC:2.7.4.21]
116710977  [KO:K19006] [EC:3.1.4.11]
116711137  inpp1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
116711585  plcd1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [KO:K05857] [EC:3.1.4.11]
116711753  [KO:K01092] [EC:3.1.3.25]
116711754  impa1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
116711759  pip4k2a; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
116712341  mtmr6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
116712647  [KO:K05858] [EC:3.1.4.11]
116713048  inpp5a; inositol polyphosphate-5-phosphatase A isoform X1 [KO:K01106] [EC:3.1.3.56]
116713427  pten; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
116713683  [KO:K03103] [EC:3.1.3.62 3.1.3.80]
116713684  [KO:K03103] [EC:3.1.3.62 3.1.3.80]
116713763  inpp5f; phosphatidylinositide phosphatase SAC2 [KO:K21798] [EC:3.1.3.-]
116714280  ocrl; LOW QUALITY PROTEIN: inositol polyphosphate 5-phosphatase OCRL [KO:K01099] [EC:3.1.3.36]
116714430  mtmr7; myotubularin-related protein 7 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
116714649  [KO:K15909] [EC:3.1.3.86]
116714669  [KO:K00911] [EC:2.7.1.127]
116715830  [KO:K05857] [EC:3.1.4.11]
116716026  [KO:K01109] [EC:3.1.3.66]
116717181  [KO:K21797] [EC:3.1.3.-]
116717264  [KO:K00889] [EC:2.7.1.68]
116717324  inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
116717606  tpi1; triosephosphate isomerase [KO:K01803] [EC:5.3.1.1]
116717898  [KO:K19801] [EC:2.7.1.67]
116717920  pip4k2c; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
116718584  ppip5k1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
116719773  pip4k2b; phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
116719948  [KO:K18083] [EC:3.1.3.64 3.1.3.95]
116720061  pi4k2b; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
116720422  inpp4b; inositol polyphosphate 4-phosphatase type II isoform X1 [KO:K01109] [EC:3.1.3.66]
116720630  pi4k2a; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
116720828  plch2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 isoform X1 [KO:K19006] [EC:3.1.4.11]
116721418  [KO:K01092] [EC:3.1.3.25]
116721520  [KO:K00889] [EC:2.7.1.68]
116721571  [KO:K00922] [EC:2.7.1.153]
116721797  [KO:K05857] [EC:3.1.4.11]
116722825  pikfyve; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
116723036  inpp4a; inositol polyphosphate-4-phosphatase type I A [KO:K01109] [EC:3.1.3.66]
116723683  plcd4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1 [KO:K05857] [EC:3.1.4.11]
116724537  [KO:K00889] [EC:2.7.1.68]
116724922  [KO:K00888] [EC:2.7.1.67]
116724954  [KO:K24222]
116724999  pip5kl1; phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform X1 [KO:K13712] [EC:2.7.1.68]
116725415  [KO:K01116] [EC:3.1.4.11]
116725537  [KO:K21289] [EC:2.7.1.153]
116725556  pip5k1c; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
116725670  [KO:K00922] [EC:2.7.1.153]
116726004  [KO:K00922] [EC:2.7.1.153]
116726019  [KO:K00922] [EC:2.7.1.153]
116726288  inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
116726578  [KO:K03103] [EC:3.1.3.62 3.1.3.80]
116726967  ipmk; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
116727279  plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
116727299  [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
116727966  [KO:K24222]
116728103  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
116728174  mtmr2; myotubularin-related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
116728253  mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
116728299  synj1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
116729357  mtmr3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
116729409  [KO:K00889] [EC:2.7.1.68]
116729761  pi4ka; phosphatidylinositol 4-kinase alpha isoform X1 [KO:K00888] [EC:2.7.1.67]
116729866  [KO:K24222]
116729906  [KO:K01106] [EC:3.1.3.56]
116730299  inpp5e; phosphatidylinositol polyphosphate 5-phosphatase type IV [KO:K20278] [EC:3.1.3.36]
116730595  [KO:K19801] [EC:2.7.1.67]
116730650  [KO:K01771] [EC:4.6.1.13]
116731103  [KO:K01803] [EC:5.3.1.1]
116731295  [KO:K00889] [EC:2.7.1.68]
116731780  [KO:K00923] [EC:2.7.1.154]
116731787  [KO:K05861] [EC:3.1.4.11]
116731870  [KO:K21797] [EC:3.1.3.-]
116732481  [KO:K00922] [EC:2.7.1.153]
116732524  [KO:K18081] [EC:3.1.3.64 3.1.3.95]
116732528  [KO:K01108] [EC:3.1.3.64 3.1.3.95]
116732702  [KO:K05858] [EC:3.1.4.11]
116733006  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
116733614  plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
116733615  plcb4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
116734279  itpkb; inositol-trisphosphate 3-kinase B isoform X1 [KO:K00911] [EC:2.7.1.127]
116734323  fig4; polyphosphoinositide phosphatase [KO:K22913] [EC:3.1.3.-]
116734418  [KO:K00140] [EC:1.2.1.18 1.2.1.27]
116734963  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform X1 [KO:K00999] [EC:2.7.8.11]
116735359  [KO:K05857] [EC:3.1.4.11]
116736783  pik3cg; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
116736860  [KO:K13024] [EC:2.7.4.24]
116737547  itpkc; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
Compound
C00024  Acetyl-CoA
C00092  D-Glucose 6-phosphate
C00111  Glycerone phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00137  myo-Inositol
C00191  D-Glucuronate
C00222  3-Oxopropanoate
C00558  D-Tagaturonate
C00641  1,2-Diacyl-sn-glycerol
C00691  2,4,6/3,5-Pentahydroxycyclohexanone
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C03659  D-Bornesitol
C03660  L-Bornesitol
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04287  3D-3,5/4-Trihydroxycyclohexane-1,2-dione
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04520  1D-myo-Inositol 3,4,5,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04563  D-myo-Inositol 1,2,4,5,6-pentakisphosphate
C04579  Inositol 1,2,3,5,6-pentakisphosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C06153  scyllo-Inositol
C06892  2-Deoxy-5-keto-D-gluconic acid
C06893  2-Deoxy-5-keto-D-gluconic acid 6-phosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C16737  5-Deoxy-D-glucuronate
C19794  CDP-1L-myo-inositol
C19799  Bis(1L-myo-inositol)-3,1'-phosphate 1-phosphate
C19891  1D-chiro-Inositol
C20251  1-Keto-D-chiro-inositol
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
C21643  3-Dehydro-scyllo-inosose
C21644  5-Dehydro-L-gluconate
Reference
PMID:14993306
  Authors
Yoshida K, Yamaguchi M, Ikeda H, Omae K, Tsurusaki K, Fujita Y
  Title
The fifth gene of the iol operon of Bacillus subtilis, iolE, encodes 2-keto-myo-inositol dehydratase.
  Journal
Microbiology 150:571-80 (2004)
DOI:10.1099/mic.0.26768-0
Reference
PMID:18310071
  Authors
Yoshida K, Yamaguchi M, Morinaga T, Kinehara M, Ikeuchi M, Ashida H, Fujita Y.
  Title
myo-Inositol catabolism in Bacillus subtilis.
  Journal
J Biol Chem 283:10415-24 (2008)
DOI:10.1074/jbc.M708043200
Related
pathway
xhe00010  Glycolysis / Gluconeogenesis
xhe00020  Citrate cycle (TCA cycle)
xhe00040  Pentose and glucuronate interconversions
xhe00564  Glycerophospholipid metabolism
KO pathway
ko00562   

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