KEGG   PATHWAY: xla00250
Entry
xla00250                    Pathway                                
Name
Alanine, aspartate and glutamate metabolism - Xenopus laevis (African clawed frog)
Class
Metabolism; Amino acid metabolism
Pathway map
xla00250  Alanine, aspartate and glutamate metabolism
xla00250

Module
xla_M00027  GABA (gamma-Aminobutyrate) shunt [PATH:xla00250]
Other DBs
GO: 0006522 0006531 0006536
Organism
Xenopus laevis (African clawed frog) [GN:xla]
Gene
100036784  aldh4a1.L; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
100137647  gad1.2.L; glutamate decarboxylase 1 isoform X1 [KO:K01580] [EC:4.1.1.15]
100174794  asns.L; asparagine synthetase [glutamine-hydrolyzing] [KO:K01953] [EC:6.3.5.4]
100381107  gad2.L; glutamate decarboxylase 2 [KO:K01580] [EC:4.1.1.15]
108695476  gpt.S; alanine aminotransferase 2-like isoform X1 [KO:K00814] [EC:2.6.1.2]
108696039  [KO:K18310] [EC:6.3.1.17 6.3.2.41]
108696283  glud1.L; glutamate dehydrogenase, mitochondrial [KO:K00261] [EC:1.4.1.3]
108696562  [KO:K03334] [EC:1.4.3.2]
108696583  [KO:K18311] [EC:6.3.2.41 6.3.2.42]
108696644  il4i1.L; L-amino-acid oxidase [KO:K03334] [EC:1.4.3.2]
108697330  [KO:K18310] [EC:6.3.1.17 6.3.2.41]
108697734  nat8l.L; N-acetylaspartate synthetase [KO:K18309] [EC:2.3.1.17]
108697935  [KO:K14454] [EC:2.6.1.1]
108700639  [KO:K01915] [EC:6.3.1.2]
108701492  gls.L; glutaminase kidney isoform, mitochondrial isoform X1 [KO:K01425] [EC:3.5.1.2]
108702988  gad1.1.S; glutamate decarboxylase 1 [KO:K01580] [EC:4.1.1.15]
108703081  gls.S; glutaminase kidney isoform, mitochondrial isoform X1 [KO:K01425] [EC:3.5.1.2]
108705425  agxt2.S; alanine--glyoxylate aminotransferase 2, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
108706518  nat8l.S; N-acetylaspartate synthetase [KO:K18309] [EC:2.3.1.17]
108706597  ppat.S; amidophosphoribosyltransferase isoform X1 [KO:K00764] [EC:2.4.2.14]
108707586  [KO:K14592] [EC:3.4.17.21]
108707927  aspa.L; aspartoacylase isoform X1 [KO:K01437] [EC:3.5.1.15]
108708575  gls2.L; glutaminase liver isoform, mitochondrial isoform X1 [KO:K01425] [EC:3.5.1.2]
108710901  [KO:K00820] [EC:2.6.1.16]
108714132  gpt2.L; alanine aminotransferase 2 [KO:K00814] [EC:2.6.1.2]
108715465  got2.S; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
108715485  [KO:K00814] [EC:2.6.1.2]
108716059  cad.L; CAD protein isoform X2 [KO:K11540] [EC:6.3.5.5 2.1.3.2 3.5.2.3]
108716182  [KO:K13051] [EC:3.5.1.1 3.4.19.5]
108716830  ddo.L; D-aspartate oxidase isoform X1 [KO:K00272] [EC:1.4.3.1]
108718166  agxt.S; serine--pyruvate aminotransferase isoform X1 [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
108718414  agxt2.L; alanine--glyoxylate aminotransferase 2, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
108719155  aldh5a1.L; succinate-semialdehyde dehydrogenase, mitochondrial [KO:K00139] [EC:1.2.1.24]
108720100  gad1.2.S; glutamate decarboxylase 1 [KO:K01580] [EC:4.1.1.15]
108720127  aldh5a1.S; succinate-semialdehyde dehydrogenase, mitochondrial [KO:K00139] [EC:1.2.1.24]
378551  gad1.1.L; glutamate decarboxylase 1 isoform X1 [KO:K01580] [EC:4.1.1.15]
379780  adss2.L; adenylosuccinate synthetase isozyme 2 [KO:K01939] [EC:6.3.4.4]
379947  got2.L; aspartate aminotransferase 2 [KO:K14455] [EC:2.6.1.1]
380175  gfpt2.L; glutamine-fructose-6-phosphate transaminase 2 L homeolog [KO:K00820] [EC:2.6.1.16]
380235  got1.S; glutamic-oxaloacetic transaminase 1 homeolog [KO:K14454] [EC:2.6.1.1]
380285  adsl.L; adenylosuccinate lyase L homeolog [KO:K01756] [EC:4.3.2.2]
380488  ass1.S; argininosuccinate synthase [KO:K01940] [EC:6.3.4.5]
380593  glul-like.1.S; glutamate-ammonia ligase S homeolog [KO:K01915] [EC:6.3.1.2]
398137  agxt.L; alanine-glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
398556  glul.L; glutamine synthetase [KO:K01915] [EC:6.3.1.2]
398751  abat.S; 4-aminobutyrate aminotransferase S homeolog [KO:K13524] [EC:2.6.1.19 2.6.1.22]
398956  ppat.L; phosphoribosyl pyrophosphate amidotransferase L homeolog [KO:K00764] [EC:2.4.2.14]
399028  abat.L; uncharacterized protein LOC399028 [KO:K13524] [EC:2.6.1.19 2.6.1.22]
414702  gfpt1.S; glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 [KO:K00820] [EC:2.6.1.16]
432308  glul-like.1.L; uncharacterized protein LOC432308 [KO:K01915] [EC:6.3.1.2]
443835  MGC82469; omega-amidase NIT2-B [KO:K13566] [EC:3.5.1.3]
444294  glul.S; glutamate-ammonia ligase S homeolog [KO:K01915] [EC:6.3.1.2]
444533  gpt.L; alanine aminotransferase 2 [KO:K00814] [EC:2.6.1.2]
444536  asrgl1.L; isoaspartyl peptidase/L-asparaginase [KO:K13051] [EC:3.5.1.1 3.4.19.5]
446858  glud1.S; glutamate dehydrogenase 1 S homeolog [KO:K00261] [EC:1.4.1.3]
447329  adss1.S; adenylosuccinate synthetase isozyme 1 B [KO:K01939] [EC:6.3.4.4]
447450  asl.L; argininosuccinate lyase isoform X1 [KO:K01755] [EC:4.3.2.1]
733340  cps1.L; carbamoyl-phosphate synthase 1 L homeolog [KO:K01948] [EC:6.3.4.16]
735084  adss1.L; adenylosuccinate synthetase isozyme 1 A [KO:K01939] [EC:6.3.4.4]
779367  nit2.S; omega-amidase NIT2-A [KO:K13566] [EC:3.5.1.3]
Compound
C00014  Ammonia
C00022  Pyruvate
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00036  Oxaloacetate
C00041  L-Alanine
C00042  Succinate
C00049  L-Aspartate
C00064  L-Glutamine
C00122  Fumarate
C00152  L-Asparagine
C00158  Citrate
C00169  Carbamoyl phosphate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00352  D-Glucosamine 6-phosphate
C00402  D-Aspartate
C00438  N-Carbamoyl-L-aspartate
C00940  2-Oxoglutaramate
C01042  N-Acetyl-L-aspartate
C02362  2-Oxosuccinamate
C03090  5-Phosphoribosylamine
C03406  N-(L-Arginino)succinate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03912  (S)-1-Pyrroline-5-carboxylate
C12270  N-Acetylaspartylglutamate
C20775  beta-Citryl-L-glutamate
C20776  N-Acetylaspartylglutamylglutamate
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:9687539
  Authors
Wu G
  Title
Intestinal mucosal amino acid catabolism.
  Journal
J Nutr 128:1249-52 (1998)
DOI:10.1093/jn/128.8.1249
Related
pathway
xla00010  Glycolysis / Gluconeogenesis
xla00020  Citrate cycle (TCA cycle)
xla00220  Arginine biosynthesis
xla00230  Purine metabolism
xla00240  Pyrimidine metabolism
xla00260  Glycine, serine and threonine metabolism
xla00330  Arginine and proline metabolism
xla00340  Histidine metabolism
xla00410  beta-Alanine metabolism
xla00470  D-Amino acid metabolism
xla00480  Glutathione metabolism
xla00520  Amino sugar and nucleotide sugar metabolism
xla00620  Pyruvate metabolism
xla00630  Glyoxylate and dicarboxylate metabolism
xla00650  Butanoate metabolism
xla00760  Nicotinate and nicotinamide metabolism
xla00770  Pantothenate and CoA biosynthesis
xla00860  Porphyrin metabolism
xla00910  Nitrogen metabolism
KO pathway
ko00250   

DBGET integrated database retrieval system