KEGG   ORTHOLOGY: K12314
Entry
K12314                      KO                                     

Name
ACTC1
Definition
actin, alpha cardiac muscle
Pathway
ko04260  Cardiac muscle contraction
ko04261  Adrenergic signaling in cardiomyocytes
ko05410  Hypertrophic cardiomyopathy
ko05414  Dilated cardiomyopathy
Disease
H00292  Hypertrophic cardiomyopathy
H00294  Dilated cardiomyopathy
H00546  Atrial septal defect
H01216  Left ventricular noncompaction
H01219  Restrictive cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    K12314  ACTC1; actin, alpha cardiac muscle
   04261 Adrenergic signaling in cardiomyocytes
    K12314  ACTC1; actin, alpha cardiac muscle
 09160 Human Diseases
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    K12314  ACTC1; actin, alpha cardiac muscle
   05414 Dilated cardiomyopathy
    K12314  ACTC1; actin, alpha cardiac muscle
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K12314  ACTC1; actin, alpha cardiac muscle
   04147 Exosome
    K12314  ACTC1; actin, alpha cardiac muscle
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actins
    Actins
     K12314  ACTC1; actin, alpha cardiac muscle
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   K12314  ACTC1; actin, alpha cardiac muscle
  Exosomal proteins of bladder cancer cells
   K12314  ACTC1; actin, alpha cardiac muscle
Genes
HSA: 70(ACTC1)
PTR: 453307(ACTC1)
PPS: 100987752(ACTC1)
GGO: 101150071(ACTC1)
PON: 100442237
NLE: 100603570(ACTC1)
MCC: 697367(ACTC1)
MCF: 102135975(ACTC1)
CSAB: 103245896(ACTC1)
RRO: 104665644(ACTC1)
RBB: 108543689(ACTC1)
CJC: 100398865(ACTC1)
SBQ: 101037742(ACTC1)
MMU: 11464(Actc1)
MCAL: 110308886(Actc1)
MPAH: 110317581(Actc1)
RNO: 29275(Actc1)
MUN: 110555967(Actc1)
CGE: 100766388(Actc1)
NGI: 103740516(Actc1)
HGL: 101723544(Actc1)
CCAN: 109677781(Actc1)
OCU: 100340339(ACTC1)
TUP: 102486241(ACTC1)
CFA: 478250(ACTC1)
VVP: 112919920(ACTC1)
AML: 100464234(ACTC1)
UMR: 103673559(ACTC1) 103679895
UAH: 113242071(ACTC1)
ORO: 101383699(ACTC1)
ELK: 111158552
FCA: 101095586(ACTC1)
PTG: 102958158(ACTC1)
PPAD: 109263206(ACTC1)
AJU: 106969798(ACTC1)
BTA: 533219(ACTC1)
BOM: 102266730(ACTC1)
BIU: 109564901(ACTC1)
BBUB: 102402622(ACTC1)
CHX: 102170606(ACTC1)
OAS: 101111554(ACTC1)
SSC: 100152267(ACTC1)
CFR: 102524504(ACTC1)
CDK: 105089985(ACTC1)
BACU: 103001576(ACTC1)
LVE: 103074529(ACTC1)
OOR: 101287649(ACTC1)
DLE: 111181781(ACTC1)
PCAD: 102996486(ACTC1)
ECB: 100057678(ACTC1)
EPZ: 103549173(ACTC1)
EAI: 106835151(ACTC1)
MYB: 102247353(ACTC1)
MYD: 102763375(ACTC1)
MNA: 107543021(ACTC1)
HAI: 109386250(ACTC1)
DRO: 112311247(ACTC1)
PALE: 102880535(ACTC1)
RAY: 107508080(ACTC1)
MJV: 108396706
LAV: 100658146(ACTC1)
TMU: 101341415
MDO: 100026925(ACTC1)
SHR: 100918763(ACTC1)
PCW: 110214160(ACTC1)
OAA: 100086207(ACTC1) 100088994
GGA: 423298(ACTC1) 426652(ACTBL2L)
CJO: 107311421(ACTA1) 107314384 107314994(ACTC1)
NMEL: 110400816(ACTC1) 110401710
APLA: 101792025(ACTC1) 101803316
ACYG: 106031717(ACTC1) 106044622
TGU: 100229664(ACTC1)
LSR: 110475286(ACTC1)
SCAN: 103826575(ACTC1)
GFR: 102038037(ACTC1)
FAB: 101808145(ACTC1)
PHI: 102099989(ACTC1)
PMAJ: 107206305(ACTC1)
CCAE: 111942704
CCW: 104684380(ACTC1)
ETL: 114055305(ACTC1)
FPG: 101914921(ACTC1) 101915966
FCH: 102050360(ACTC1) 102051901
CLV: 102084489 102093431(ACTC1)
EGZ: 104126475(ACTC1)
NNI: 104009401 104015900(ACTC1)
ACUN: 113480547(ACTC1) 113481280
PADL: 103921934(ACTC1) 103925776
AAM: 106482816(ACTC1) 106498226
AMJ: 102570695 106736711(ACTC1)
CMY: 102931639 102939680(ACTC1)
CPIC: 101941415 101944575(ACTC1)
TSR: 106552958
XLA: 108699710 108716753 379351(MGC53823) 379752(actc1.L) 432314(acta1.L) 779096 779129(act2) 780761
XTR: 394673(acta4) 394698(actc1) 394982(MGC75582) 448346(acta1)
DRE: 337770(si:ch73-187m15.4) 408256(actc1a) 415164(acte1) 550445(acta1a) 570210(actc2) 58114(actc1b)
PRET: 103457336 103458530 103458759(actc1) 103462807(acta1)
LCM: 102352337(ACTC1) 102364634
CMK: 103175184(actc1) 103180967
AGS: 114120988
RMD: 113557908
 » show all
Reference
  Authors
Jiang HK, Qiu GR, Li-Ling J, Xin N, Sun KL
  Title
Reduced ACTC1 expression might play a role in the onset of congenital heart disease by inducing cardiomyocyte apoptosis.
  Journal
Circ J 74:2410-8 (2010)
DOI:10.1253/circj.CJ-10-0234
  Sequence
[hsa:70] [rno:29275]
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