Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ.

The SOCS box: a tale of destruction and degradation.

Trends Biochem Sci 27:235-41 (2002)
DOI:10.1016/S0968-0004(02)02085-6

[hsa:30837]

Banks AS, Li J, McKeag L, Hribal ML, Kashiwada M, Accili D, Rothman PB

Deletion of SOCS7 leads to enhanced insulin action and enlarged islets of Langerhans.

J Clin Invest 115:2462-71 (2005)
DOI:10.1172/JCI23853

[hsa:30837] [mmu:192157]

Krebs DL, Uren RT, Metcalf D, Rakar S, Zhang JG, Starr R, De Souza DP, Hanzinikolas K, Eyles J, Connolly LM, Simpson RJ, Nicola NA, Nicholson SE, Baca M, Hilton DJ, Alexander WS

SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation.

Mol Cell Biol 22:4567-78 (2002)
DOI:10.1128/MCB.22.13.4567-4578.2002

[hsa:9306]

Bayle J, Lopez S, Iwai K, Dubreuil P, De Sepulveda P

The E3 ubiquitin ligase HOIL-1 induces the polyubiquitination and degradation of SOCS6 associated proteins.

FEBS Lett 580:2609-14 (2006)
DOI:10.1016/j.febslet.2006.03.093

[mmu:54607]