KEGG ORTHOLOGY: K05764

ORTHOLOGY: K05764

Entry

K05764                      KO

Symbol

TMSB4

Name

thymosin, beta 4

Pathway

map04810

Regulation of actin cytoskeleton

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K05764  TMSB4; thymosin, beta 4
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K05764  TMSB4; thymosin, beta 4
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Thymosin
     K05764  TMSB4; thymosin, beta 4

Genes

HSA:	7114(TMSB4X) 9087(TMSB4Y)

PTR:	101058899 101059399 104004853 104007609 134807627 465493(TMSB4X)

PPS:	100987645 103785151 103785506 103786747 117977621(TMSB4X) 129395546(TMSB4Y)

GGO:	101131259 101152912(TMSB4X) 109024294 109024295 129530270

PON:	100173314(TMSB4X) 129052300 129053406

PPYG:

129022134 129025121(TMSB4X)

NLE:	100586905(TMSB4X) 101179388

HMH:	116461128 116463097 116812262(TMSB4X)

SSYN:

129474570 129475898(TMSB4X) 129476699

MCC:	710959(TMSB4X)

MCF:	102127641 123571114 135964439(TMSB4X)

MTHB:

126940158 126945714 126946672 126954764 126956130

MNI:	105478272(TMSB4X)

CSAB:

103231603(TMSB4X)

CATY:

105574712(TMSB4X) 105592075

PANU:

101021035(TMSB4X)

TGE:	112615031(TMSB4X) 112627064

MLEU:

105550029(TMSB4X)

RRO:	104657315 104678077(TMSB4X)

RBB:	108520703(TMSB4X)

TFN:	117069475 117071591 117078150(TMSB4X) 117085595

PTEH:

111520249 111522328 111531688(TMSB4X)

CANG:

105517290 105518046(TMSB4X)

CJC:	100392150 100399195(TMSB4X) 100399497 103787614 103787919 103788967 103794171

SBQ:	104650983(TMSB4X)

CIMI:

108288896 108289377 108304905 108317590 119471502

ANAN:

105705294(TMSB4X) 105713823 105716848 105723546

CSYR:

103261809 103264132 103268519 103269809 103272116

MMUR:

105882437(TMSB4X)

LCAT:

123627995(TMSB4X) 123628887 123629086 123632663

PCOQ:

105808462 105820968(TMSB4X) 105821997

OGA:	100953997 100966053(TMSB4X)

MMU:	19241(Tmsb4x)

MCAL:

110286700(Tmsb4x)

MPAH:

110313482(Tmsb4x)

RNO:	103692338(Tmsb4xl2) 120095326 81814(Tmsb4x)

MCOC:

116100927 116101268(Tmsb4x)

ANU:	117695451(Tmsb4x)

ASYL:

127674808(Tmsb4x)

MUN:	110559826 110566561(Tmsb4x)

CGE:	100765498 100774337 103163771 118239413

MAUA:

101840813(Tmsb4x) 101843363 121141187

PLEU:

114699182 114702040 114702939(Tmsb4x)

MORG:

121439492(Tmsb4x) 121444431

MFOT:

126512679

AAMP:

119802017 119804838(Tmsb4x) 119808072

NGI:	103736273 103749967(Tmsb4x)

HGL:	101726037(Tmsb4x)

CPOC:

100736168(Tmsb4x)

DORD:

105997661(Tmsb4x)

DSP:	122108525(Tmsb4x)

PLOP:

125343952(Tmsb4x)

NCAR:

124972417

MMMA:

125613219(Tmsb4x)

ITI:	101956985(Tmsb4x) 101965446 110598795 120892252

OCU:

127485645

GVR:	103589396(TMSB4X) 103597041

CFA:	100683370 100684977(TMSB4X) 102152706 102153128 102156038 102156243

CLUD:

112641366 112644094 112652923(TMSB4X) 112662978 112670450 112671984

VVP:	112912562 112913177 112932374(TMSB4X)

VLG:	121473603 121476247 121483583(TMSB4X) 121484091 121494315

NPO:	129512351 129518215(TMSB4X) 129522081 129523045

AML:	100465730(TMSB4X) 117799178

UMR:	121099774(TMSB4X)

UAH:	113240727(TMSB4X) 113248368

UAR:	123788659 123796367(TMSB4X)

ELK:	111139463 111157089

LLV:	125081712 125091678 125092617 125092774 125099025 125099060 125100573 125105009 125106706

MPUF:

101674359 101686475(TMSB4X)

MNP:	132006969(TMSB4X) 132008041 132012202 132013210 132014019

MLK:	131820700 131820748(TMSB4X) 131825586 131826555 131829555 131830520 131835365

NVS:	122897234(TMSB4X)

ORO:	101363856 101369247(TMSB4X) 101375913 101381115 101381377

EJU:	114196837 114203691 114204859 114215850 114218040(TMSB4X)

ZCA:	113909966 113912974 113918360 113920062 113920131 113924121 113929607 113930221 113930732 113930795(TMSB4X) 113934450 113935664 113935678 118355939

MLX:	118006256 118008568 118009324 118013638 118016517 118022882 118025919 118026719(TMSB4X)

NSU:	110570548 110573402 110573752(TMSB4X) 110580532 110581101 110585870 110590166 110590979

LWW:	102744307(TMSB4X) 115937458

FCA:	101083316 101088815(TMSB4X) 109496027

PYU:	121021267 121038160

PCOO:

112851932 112871639(TMSB4X)

PBG:	122476911(TMSB4X) 122485339 122496041

PVIV:

125156166 125157427(TMSB4X) 125167580

LRUF:

124507415 124509350 124519152

LGF:	123586115 123594154(TMSB4X) 123596821

AJU:	106979765 113597691

PTG:	102957343 102964367(TMSB4X)

PPAD:

109248295(TMSB4X)

PUC:	125924852 125931480

PLEZ:

122210841 122212658(TMSB4X)

HHV:	120233139(TMSB4X)

BTA:	101906565 112441594 132344337 282386(TMSB4X) 785745

BOM:	102274241 102274488 102282148(TMSB4X) 138989917

BIU:	109555310(TMSB4X)

BBUB:

102400520 102408521(TMSB4X) 102413106

BBIS:

104981309(TMSB4X) 104992938 104993636

CHX:	102182562 102467078(TMSB4X)

OAS:	101102859 101119695(TMSB4X) 105602398 105609988 106990481 114110488 114114600

CSUM:

138070988(TMSB4X) 138073983 138076526 138079889 138081500 138085850 138092934 138095441

ODA:	120853583 120854703 120872966 120873649 120882449(TMSB4X)

CCAD:

122421209 122428344 122431405 122434952(TMSB4X) 122435477 122436418 122447516 122450429

MREE:

136144364 136147035 136147396 136154105(TMSB4X) 136157860 136163384 136168923

OVR:	110121871 110122184 110134685 110137555 110141329 110147389 110147393 139030450 139031053 139031292 139031300 139035645 139038618

SSC:	110257905 733606(TMSB4X)

CFR:	102513534 102517367(TMSB4X) 102521012 116663341

CBAI:

105077755(TMSB4X)

CDK:	105085609 105104035 116150826(TMSB4X)

VPC:	102542158(TMSB4X)

BACU:

103017932(TMSB4X)

BMUS:

118887180 118888357 118889210(TMSB4X) 118889468 118903060

LVE:	103076075 103082311(TMSB4X)

OOR:	101273310 101280441 101287861(TMSB4X) 101288882 105748330 125965441

LALB:

132505072 132512921(TMSB4X) 132519414

DLE:	111167214(TMSB4X)

PCAD:

102976438 102991719(TMSB4X)

PSIU:

116740266 116745323 116747691(TMSB4X) 116754331

PPHC:

136123500 136134758 136142402(TMSB4X)

NASI:

112397576 112401846

ECB:	100034015(TMSB4X)

EAI:	106843063 106848622(TMSB4X)

MYB:	102238686 102243622 102258778(TMSB4X) 106725993

MYD:	102765056 107184314

MMYO:

118651348 118654191(TMSB4X) 118656428

MLF:

102438960

MDT:	132212040 132222015 132223271 132225263(TMSB4X) 132225994 132228083 132231634 132232385 132236869

MYUM:

139000549 139001627 139005130 139005246 139005784 139008048 139008163 139014389 139018324 139020506

PKL:	118714209 118720033(TMSB4X) 118722721

EFUS:

103299726(TMSB4X) 114230917 129148706

MNA:

107525072

DRO:

112316977

SHON:

118980980 118983072 118987229(TMSB4X)

AJM:	119038262 119045876 119055086 119058331(TMSB4X) 128627765

PDIC:

114489889 114494311 114498412 114500980 114502021 114505231(TMSB4X) 114514844

PHAS:

123811857 123817522 123819697 123821608 123830016(TMSB4X)

MMF:	118618617 118630150 118636432(TMSB4X) 118642345

PPAM:

129070267 129076805 129076900(TMSB4X) 129079877 129082281 129082289 129083367 129083506 129084534

HAI:	109387357(TMSB4X)

RFQ:	117023829 117026948 117028776(TMSB4X) 117029073

PALE:

102888843(TMSB4X) 102893652

PVP:	105293982(TMSB4X)

RAY:	107497575(TMSB4X) 107503371 107506326 107506466 107512154 118609386

MJV:	118972785(TMSB4X)

TOD:	119246339(TMSB4X) 119246783 119250755 119258726

SARA:

101555822(TMSB4X)

SFUM:

130028301 130039341(TMSB4X)

SETR:

125999119(TMSB4X)

LAV:	100668370(TMSB4X)

TMU:

101348206

ETF:	101644072(TMSB4X) 105979637

DNM:	101414099 111760526 111761136 111764963

MDO:	100017869(TMSB4X) 100617751 100619033

GAS:	123239682(TMSB4X) 123251822

SHR:	100921944(TMSB4X)

AFZ:

127553642

PCW:	110199283 110222454(TMSB4X)

TVP:	118839421(TMSB4X) 118848311 118848664 118851794

PBRV:

138142059 138145437 138161753 138164076

OAA:	100082242(TMSB4X)

TACU:

119937871(TMSB4X)

GGA:	408047(TMSB4X) 770993(TMSB4Y)

PCOC:

116230750(TMSB4X)

MGP:

100539160

CJO:	107320133 107325932(TMSB4X)

TPAI:

128071698(TMSB4X) 128084070

LMUT:

125693719(TMSB4X) 125700105

NMEL:

110405293(TMSB4X) 110405460

APLA:

101796464 113841592(TMSB4X)

ACYG:

106032794 136786860(TMSB4X)

CATA:

118245770(TMSB4X) 118254919

AFUL:

116494776 116501949(TMSB4X)

TGU:	100190752(TMSB4X) 100232010

LSR:	110473214(TMSB4X) 110482711

SCAN:

103815807(TMSB4X) 103817276

PMOA:

120498617 120504632(TMSB4X)

OTC:	121332367 121342230(TMSB4X)

PRUF:

121356195(TMSB4X) 121361399

ATRC:

139591666(TMSB4X) 139597913

GFR:	102041951 102043761(TMSB4X)

FAB:	101817032 101820252(TMSB4X)

OMA:	130256864(TMSB4X) 130258588

PHI:	102104803(TMSB4X) 102105621

PMAJ:

107205483(TMSB4X) 107210896

CCAE:

111922816(TMSB4X) 111935573

CCW:	104686151(TMSB4X) 104689605

CBRC:

103611725(TMSB4X) 103614664

ACOE:

138104351(TMSB4X) 138118408

ETL:	114065208 114068932(TMSB4X)

ZAB:	102066892 102071605(TMSB4X)

ZLE:	135445639(TMSB4X) 135453693

ACHL:

103807408(TMSB4X)

SVG:	106852904(TMSB4X) 106857365

MMEA:

130588439(TMSB4X)

HRT:	120748552(TMSB4X) 120759254

SATI:

136358053(TMSB4X) 136367295

CCIC:

134049647 134058046(TMSB4X)

FPG:

101922739

FCH:

102057308

CCRI:

104163491(TMSB4X)

NNT:	104404754 104407231(TMSB4X)

SHAB:

115615599

ACUN:

113485195(TMSB4X)

TALA:

104366358 116963585(TMSB4X)

ACHC:

115334130 115334602(TMSB4X)

HALD:

104312823(TMSB4X)

HLE:	104838875(TMSB4X)

AGEN:

126050918 126052912

HHAR:

128135076(TMSB4X) 128155096

GCL:	127016427 127022050

CSTI:

104552614(TMSB4X)

LDI:	104346547(TMSB4X)

MNB:	103780369(TMSB4X)

DPUB:

104297073(TMSB4X) 104309771

PPUS:

135175235(TMSB4X) 135185033

AVIT:

104272549(TMSB4X)

BRHI:

104490320(TMSB4X)

EGZ:	104128435(TMSB4X)

NNI:	104018453(TMSB4X)

PCRI:

104026783(TMSB4X)

PCAO:

104050991(TMSB4X)

PADL:

103915764(TMSB4X)

AFOR:

103904414

FGA:	104080415(TMSB4X)

GSTE:

104253194(TMSB4X)

CBOY:

140646097(TMSB4X) 140656701

CLV:	102087997 102093701(TMSB4X)

CNIC:

135993238(TMSB4X) 135993994

MUI:	104534927 104541718(TMSB4X)

PLET:

104615313(TMSB4X)

EHS:	104508719(TMSB4X)

CMAC:

104482426(TMSB4X)

CUCA:

104059218 128853358(TMSB4X)

TEO:	104381940(TMSB4X)

BREG:

104643225(TMSB4X)

OHA:	104326879(TMSB4X)

ACAR:

104529563(TMSB4X)

CPEA:

104386626

CVF:	104291838(TMSB4X)

RTD:	128904053(TMSB4X) 128916166

CRID:

134518699(TMSB4X) 134521966

AAM:	106491689(TMSB4X)

AROW:

112964604(TMSB4X) 112964779

NPD:	112954086(TMSB4X) 112954518

TGT:	104580784(TMSB4X)

DNE:	112984243 112993564(TMSB4X)

SCAM:

104141074 104149807(TMSB4X)

ASN:	102372878(TMSB4X) 102379609

AMJ:	102564466(TMSB10) 102577269(TMSB4X)

CPOO:

109306062(TMSB4X) 109310122

GGN:	109289926 109303190(TMSB4X)

PSS:	102445810(TMSB4X)

CMY:	102936580(TMSB4X)

CCAY:

125641243(TMSB4X)

DCC:	119846647(TMSB4X)

CPIC:

101946282(TMSB4X)

TST:	117869846(TMSB4X)

CABI:

116834069(TMSB4X)

MRV:	120401258(TMSB4X)

ACS:	100558923 100560572(tmsb4x)

ASAO:

132768915 132771673(TMSB4X)

PVT:	110073493 110075478(TMSB4X)

SUND:

121920178 121926208(TMSB4X)

PBI:	103048757 103053440(TMSB4X)

PMUR:

107289018 107302470(TMSB4X)

CTIG:

120306498(TMSB4X) 120310620

TSR:	106557433(TMSB4X)

PGUT:

117655722 117676114(TMSB4X) 132709545 132710266

APRI:

131192022 131199896(TMSB4X)

PTEX:

113433510 113445184(TMSB4X)

NSS:	113411702(TMSB4X) 113424882

VKO:	123024398(TMSB4X) 123035852

PMUA:

114596288(TMSB4X)

PRAF:

128402412 128407910 128413210(TMSB4X)

ZVI:	118081534 118084643(TMSB4X)

HCG:	128342471 128352396(TMSB4X)

GJA:	107124268(TMSB4X)

STOW:

125431653(TMSB4X)

EMC:	129326478(TMSB4X) 129335588 129342530

XLA:	108709680 399438(tmsb4x.L)

XTR:	733468(tmsb4x)

NPR:	108794930(TMSB4X)

RTEM:

120924959 120926527(TMSB4X)

ACAT:

141107380 141114207 141127948(TMSB4X)

BBUF:

120995635(TMSB4X)

BGAR:

122931141(TMSB4X)

DTC:	141098404(TMSB4X)

PWL:	138250172(TMSB4X)

MUO:	115469188(TMSB4X)

GSH:	117363098(TMSB4X)

DRE:	402820(tmsb) 566329(tmsb2) 793949(tmsb4x)

SRX:	107742637(tmsb4x)

SANH:

107667660(tmsb4x)

SGH:	107552380(tmsb4x)

CCAR:

109055448 109081903(tmsb) 109093913 109102189(tmsb2) 109113719 122146174

CAUA:

113038537 113044360 113052908 113057711 113058139 113063754 113080004 113108206 113113906

CGIB:

127942155 127949669 127964788 127970961 127986621 128020247 128027130

PTET:

122326749(tmsb) 122333058(tmsb4x) 122348417 122357381(tmsb2)

LROH:

127152395(tmsb) 127171007(tmsb4x) 127176575(tmsb2)

GRF:	141288689(tmsb2) 141292932(tmsb) 141337377

OMC:	131529029(tmsb) 131542446 131546820(tmsb4x)

PPRM:

120479172(tmsb4x) 120494490(tmsb)

RKG:	130072547(tmsb4x) 130087809 130095188(tmsb2)

MAMB:

125252741(tmsb) 125259292(tmsb2) 125270862(tmsb4x) 125272311

CIDE:

127494616 127503838 127514847 127518377

CERY:

137012895(tmsb) 137013187(tmsb2) 137031722 137035351(tmsb4x)

MASI:

127412964 127417879 127428864 127443750 127447011 127448290

MANU:

129422396(tmsb2) 129424512(tmsb) 129451955(tmsb4x)

PDAB:

135757568(tmsb2) 135776877(tmsb)

IPU:	100304709(tmsb4x) 108258993 128633468

IFU:	128601886 128609283(tmsb4x) 128611160(tmsb2)

PHYP:

113524350 113528828 113537489

SMEO:

124378237 124379970(tmsb4x) 124386167(tmsb2)

TFD:	113635593(tmsb2) 113642092 113649010(tmsb4x)

TVC:	132839324(tmsb4x) 132855996(tmsb2)

CGAR:

128507650(tmsb) 128524707(tmsb4x) 128532052(tmsb2)

NGRA:

132866158 132890122(tmsb2) 132896432

TRN:	134318968(tmsb2) 134324294 134329288

AMEX:

103024855 103025385(tmsb4x) 111195815(tmsb2)

CMAO:

118797910 118807134(tmsb2) 118811369(tmsb4x)

EEE:	113587186 113588867 113590739

TRU:

115252437

TFS:	130531579(tmsb2)

TNG:	GSTEN00026074G001 GSTEN00031637G001

LCO:	104924244 104935059

NCC:

104949035

TBEN:

117475184(tmsb2) 117499164

CGOB:

115015172

PGEO:

117453358(tmsb2)

GACU:

117545202(tmsb2)

ELY:	117250359(tmsb4x) 117255705 117260707(tmsb2)

EFO:	125884878 125894381(tmsb2)

SLUC:

116044686 116052079(tmsb2)

ECRA:

117939145 117951983(tmsb2)

ESP:

116696951

PFLV:

114562901

GAT:	120818489(tmsb2)

PPUG:

119211601(tmsb2)

AFB:	129089869(tmsb2) 129104156(tmsb4x) 129111767

CLUM:

117737423(tmsb2) 117743024

PSWI:

130204382 130210111(tmsb2)

CANA:

137789948(tmsb2) 137794085

CVE:	137875867(tmsb2) 137879002

MSAM:

119888170(tmsb2) 119903756 119904160(tmsb4x)

SCHU:

122872079 122880869(tmsb2) 122885978(tmsb4x)

SPUL:

138592093(tmsb4x) 138598048(tmsb2) 138603525

ALAT:

119007790(tmsb2) 119015093

ASTR:

137591300 137602801(tmsb2)

MZE:	101466144(tmsb4x) 101466672

ONL:	100702585(tmsb4x) 100706016

OAU:	116315142(tmsb2) 116323112

XMA:	102217051 102221182 111609250

XCO:	114139755 114140476 114148007

XHE:	116714833 116716175(tmsb4x) 116722501

PRET:

103459176 103474715

PFOR:

103132075 103151925(tmsb4x) 107835635

PLAI:

106937274 106942154(tmsb4x) 106954764

PMEI:

106919861 106924958 106931093

GAF:	122827154 122837564(tmsb2) 122839930

PPRL:

129355472 129361304(tmsb4x) 129363032(tmsb2)

CVG:	107086327 107095749(tmsb4x)

CTUL:

119780967(tmsb2) 119788793(tmsb4x) 119792314

GMU:	124861014(tmsb2) 124861626

NFU:	107380871(tmsb4x) 107395803

KMR:	108245807(tmsb2) 108246798

ALIM:

106511454 106525723

NWH:	119409107(tmsb2) 119415020 119419167(tmsb4x) 119419480 119428836

AOCE:

111583439(tmsb4x) 111588062(tmsb2)

EJA:	138200930(tmsb4x) 138207039 138211134(tmsb2)

BFRE:

138619994(tmsb2) 138623263(tmsb4x) 138628640

CSEM:

103389531

POV:	109631236(tmsb4x) 109645526

SSEN:

122765459 122778139(tmsb2)

SSOE:

131443600(tmsb4x) 131455660 131472693(tmsb2)

HHIP:

117755084(tmsb4x) 117769345(tmsb2) 117775769

HSP:	118103541 118112664(tmsb2) 118120518(tmsb4x)

PPLT:

128430882 128446180(tmsb2)

SMAU:

118282482 118319406(tmsb2)

LCF:	108882789(tmsb2) 108890952 108892885

SDU:	111218815(tmsb4x) 111226672 111236729

SLAL:

111662084(tmsb4x) 111664638 111665347

XGL:	120785362(tmsb2) 120798337 120801107(tmsb4x)

HCQ:	109524190 109528309

SSCV:

125986900(tmsb2) 125987979

SBIA:

133508712(tmsb2)

PEE:	133407778(tmsb2) 133412403

PTAO:

133478368 133484662(tmsb2) 133486819(tmsb4x)

BPEC:

110162402

ENY:	140354658(tmsb2) 140357032

MALB:

109956696 109960580(tmsb4x)

BSPL:

114846769(tmsb4x) 114851182 114864821(tmsb2)

SJO:	128354341 128363087(tmsb2) 128368186(tmsb4x)

SSCO:

133976441 133986030(tmsb2) 133992589(tmsb4x)

GMH:	115533254(tmsb4x) 115541796 115552803

SASA:

100195705(tmsb4x) 106586813(TYB12) 106604357

STRU:

115148453 115161347(tmsb4x) 115168494 115205603

OTW:	112225288 112253741 112257068 112258325

OMY:	100136027 100170202 110537822 118936315 118946058

OGO:	124000623 124011677 124044253(tmsb4x)

ONE:	115104643 115113550 115121687

OKI:	109878950 116374415

OKE:	118366706(tmsb4x) 118391022 127913948

OMM:	135518957(tmsb4x) 135527120 135545165 135548739

OCLA:

139380507 139390770

SALP:

111980683

SNH:	120033759 120044424 120047932 120050599 120062049 120064358

CCLU:

121536189(tmsb4x) 121536776(tmsb2) 121574080 121580140

ELS:	105018723 105020018 114839106 114839531

OEP:	134007388 134017263(tmsb4x) 134032369(tmsb2)

SFM:	108920507 108927832

PKI:	111846862(tmsb4x) 111848913 111851511

AANG:

118214617(tmsb4x) 118231303 118235463

AROT:

135241368 135250987 135259714 135263633

CCOG:

133123990(tmsb2) 133124059 133132941(tmsb)

LOC:	102682393(tmsb4x) 102687759

PSPA:

121297387(tmsb2) 121320653 121324043 121327477

ARUT:

117405122 117406516 117413066 117431400 117971112

PSEX:

120542718(tmsb2)

LCM:

CMK:

RTP:

CPLA:

HOC:

LERI:

HAKA:

Reference

PMID:6201851

Authors

Wodnar-Filipowicz A, Gubler U, Furuichi Y, Richardson M, Nowoswiat EF, Poonian MS, Horecker BL

Title

Cloning and sequence analysis of cDNA for rat spleen thymosin beta 4.

Journal

Proc Natl Acad Sci U S A 81:2295-7 (1984)
DOI:10.1073/pnas.81.8.2295

Sequence

[rno:81814]

LinkDB

DBGET integrated database retrieval system