KEGG   MODULE: M00030
Entry
M00030            Pathway   Module                                 
Name
Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
Definition
K01655 K17450 K01705 K05824 K00838 K00143 (K00293,K24034) K00290
Diagram
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00030

Class
Pathway modules; Amino acid metabolism; Lysine metabolism
Pathway
map00300  Lysine biosynthesis
map01230  Biosynthesis of amino acids
map01100  Metabolic pathways
Orthology
K01655  
homocitrate synthase [EC:2.3.3.14] [RN:R00271]
K17450  
homoaconitase [EC:4.2.1.-] [RN:R03444]
K01705  
homoaconitate hydratase [EC:4.2.1.36] [RN:R04371]
K05824  
homoisocitrate dehydrogenase [EC:1.1.1.87] [RN:R01934]
K00838  
2-aminoadipate transaminase [EC:2.6.1.39] [RN:R01939]
K00143  
L-2-aminoadipate reductase [EC:1.2.1.95] [RN:R03098 R04863 R04390]
K00293,K24034  
saccharopine dehydrogenase (NADP+, L-glutamate forming) [EC:1.5.1.10] [RN:R02315]
K00290  
saccharopine dehydrogenase, L-lysine forming [EC:1.5.1.7] [RN:R00715]
Complete
sce  Saccharomyces cerevisiae (budding yeast)
seub  Saccharomyces eubayanus
spao  Saccharomyces paradoxus
ago  Eremothecium gossypii
erc  Eremothecium cymbalariae
kla  Kluyveromyces lactis
kmx  Kluyveromyces marxianus
lth  Lachancea thermotolerans
vpo  Vanderwaltozyma polyspora
zro  Zygosaccharomyces rouxii
cgr  Nakaseomyces glabratus
ncs  Naumovozyma castellii
ndi  Naumovozyma dairenensis
tpf  Tetrapisispora phaffii
tgb  Torulaspora globosa
tdl  Torulaspora delbrueckii
kaf  Kazachstania africana
kng  Huiozyma naganishii
zmk  Zygotorulaspora mrakii
slud  Saccharomycodes ludwigii
dha  Debaryomyces hansenii
pic  Scheffersomyces stipitis
pgu  Meyerozyma guilliermondii
spaa  Spathaspora passalidarum
lel  Lodderomyces elongisporus
lbg  Lodderomyces beijingensis
cal  Candida albicans
ctp  Candida tropicalis
cot  Candida orthopsilosis
cdu  Candida dubliniensis
cten  Yamadazyma tenuis
clus  Clavispora lusitaniae CBS 6936
caur  Candidozyma auris
asau  Australozyma saopauloensis
ppa  Komagataella phaffii
pkz  Pichia kudriavzevii
bnn  Brettanomyces nanus
bbrx  Brettanomyces bruxellensis
opa  Ogataea parapolymorpha
yli  Yarrowia lipolytica
ncr  Neurospora crassa
pan  Podospora anserina
pbel  Podospora bellae-mahoneyi
ppsd  Podospora pseudocomata
ppsp  Podospora pseudopauciseta
ppsa  Podospora pseudoanserina
ttt  Thermothielavioides terrestris
mtm  Thermothelomyces thermophilus
cthr  Thermochaetoides thermophila
rthe  Remersonia thermophila
mgr  Pyricularia oryzae
ppei  Pyricularia pennisetigena
pgri  Pyricularia grisea
tmn  Phaeoacremonium minimum
ssck  Sporothrix schenckii
fgr  Fusarium graminearum
fpu  Fusarium pseudograminearum
fpoa  Fusarium poae
fvn  Fusarium venenatum
fvr  Fusarium verticillioides
fox  Fusarium oxysporum
ffc  Fusarium falciforme
fkr  Fusarium keratoplasticum
fmu  Fusarium musae
tre  Trichoderma reesei QM6a
tasp  Trichoderma asperellum
maw  Metarhizium acridum
maj  Metarhizium robertsii
mbrn  Metarhizium brunneum
pchm  Pochonia chlamydosporia
uvi  Ustilaginoidea virens
cmt  Cordyceps militaris
amus  Akanthomyces muscarius
plj  Purpureocillium lilacinum
ptkz  Purpureocillium takamizusanense
dcon  Drechmeria coniospora
val  Verticillium alfalfae
vda  Verticillium dahliae
cfj  Colletotrichum fioriniae
chig  Colletotrichum higginsianum
cdet  Colletotrichum destructivum
sapo  Scedosporium apiospermum
ela  Eutypa lata
pfy  Pestalotiopsis fici
ssl  Sclerotinia sclerotiorum
bfu  Botrytis cinerea (gray mold)
mbe  Drepanopeziza brunnea
psco  Mollisia scopiformis
glz  Glarea lozoyensis
ani  Aspergillus nidulans
afm  Aspergillus fumigatus
act  Aspergillus clavatus
nfi  Aspergillus fischeri
aor  Aspergillus oryzae
ang  Aspergillus niger (black aspergilli)
afv  Aspergillus flavus
aluc  Aspergillus luchuensis
ache  Aspergillus chevalieri
apuu  Aspergillus puulaauensis
pcs  Penicillium rubens
pdp  Penicillium digitatum
pou  Penicillium oxalicum
ppsf  Penicillium psychrofluorescens
tmf  Talaromyces marneffei
trg  Talaromyces rugulosus
cim  Coccidioides immitis
cpw  Coccidioides posadasii
ure  Uncinocarpus reesii
abe  Trichophyton benhamiae
tve  Trichophyton verrucosum
pbl  Paracoccidioides lutzii Pb01
pbn  Paracoccidioides brasiliensis
bgh  Blastomyces gilchristii
pno  Parastagonospora nodorum
pte  Pyrenophora teres
ptrr  Pyrenophora tritici-repentis
bze  Bipolaris zeicola
bsc  Bipolaris sorokiniana
bor  Bipolaris oryzae
aalt  Alternaria alternata
adac  Alternaria dauci
arab  Ascochyta rabiei
ztr  Zymoseptoria tritici
pfj  Pseudocercospora fijiensis
ffu  Fulvia fulva
cbet  Cercospora beticola
bcom  Baudoinia panamericana
npa  Neofusicoccum parvum
tml  Tuber melanosporum
cne  Cryptococcus deneoformans JEC21
cnb  Cryptococcus deneoformans B-3501A
cng  Cryptococcus neoformans var. grubii H99
cgi  Cryptococcus gattii
cdeu  Cryptococcus deuterogattii
cdec  Cryptococcus decagattii
cteg  Cryptococcus tetragattii
cbas  Cryptococcus bacillisporus
kmg  Kwoniella mangroviensis
kne  Kwoniella newhampshirensis
kdj  Kwoniella dejecticola
kbi  Kwoniella bestiolae
kpin  Kwoniella pini
ksh  Kwoniella shivajii
ker  Kwoniella europaea
kep  Kwoniella dendrophila
tms  Tremella mesenterica
tasa  Trichosporon asahii var. asahii
ccac  Cutaneotrichosporon cavernicola
tvs  Trametes versicolor
dsq  Dichomitus squalens
pco  Phanerochaete carnosa
shs  Stereum hirsutum
adl  Auricularia subglabra
fme  Fomitiporia mediterranea
gtr  Gloeophyllum trabeum
rsx  Rhizoctonia solani
lbc  Laccaria bicolor
abp  Agaricus bisporus var. burnettii JB137-S8
abv  Agaricus bisporus var. bisporus H97
pcub  Psilocybe cubensis (magic mushroom)
mrr  Moniliophthora roreri
more  Marasmius oreades (fairy-ring mushroom)
scm  Schizophyllum commune
cput  Coniophora puteana
sla  Serpula lacrymans
 » show all
Reaction
R00271  
R03444  
R04371  
R01934  
R01939  
R03098  
R04863  
R04390  
R02315  
R00715  
Compound
C00026  2-Oxoglutarate
C00024  Acetyl-CoA
C01251  (R)-2-Hydroxybutane-1,2,4-tricarboxylate
C04002  (Z)-But-1-ene-1,2,4-tricarboxylate
C05662  Homoisocitrate
C00322  2-Oxoadipate
C00956  L-2-Aminoadipate
C05560  L-2-Aminoadipate adenylate
C05535  alpha-Aminoadipoyl-S-acyl enzyme
C04076  L-2-Aminoadipate 6-semialdehyde
C00449  N6-(L-1,3-Dicarboxypropyl)-L-lysine
C00047  L-Lysine
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