REACTION: R00114
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Entry
R00114 Reaction
Name
L-glutamate:NADP+ oxidoreductase (transaminating)
Definition
2 L-Glutamate + NADP+ <=> L-Glutamine + 2-Oxoglutarate + NADPH + H+
Equation
2
C00025
+
C00006
<=>
C00064
+
C00026
+
C00005
+
C00080
Comment
two-step reaction (see
R00256+R00248
)
Reaction class
RC00001
C00005_C00006
RC00006
C00025_C00026
RC00010
C00025_C00064
Enzyme
1.4.1.13
Pathway
rn00250
Alanine, aspartate and glutamate metabolism
rn00910
Nitrogen metabolism
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
rn01120
Microbial metabolism in diverse environments
rn01230
Biosynthesis of amino acids
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.4 Acting on the CH-NH2 group of donors
1.4.1 With NAD+ or NADP+ as acceptor
1.4.1.13
R00114 2 L-Glutamate + NADP+ <=> L-Glutamine + 2-Oxoglutarate + NADPH + H+
BRITE hierarchy
Orthology
K00265
glutamate synthase (NADPH) large chain [EC:
1.4.1.13
]
K00266
glutamate synthase (NADPH) small chain [EC:
1.4.1.13
]
Other DBs
RHEA:
15504
LinkDB
All DBs
RCLASS: RC00010
Help
Entry
RC00010 RClass
Definition
C5a-C6a:N1a+*-*+O6a:C1b+O5a-C1b+O6a
Reactant pair
C00025_C00064
C00026_C00940
C00036_C02362
C00049_C00152
C00083_C06625
C00099_C19779
C00120_C01893
C00217_C00819
C00318_C02290
C00431_C00990
C00614_C02583
C00712_C19670
C00803_C01842
C00954_C02693
C01035_C03078
C01209_C21430
C02028_C04131
C02282_C06112
C02505_C07086
C02986_C21456
C03402_C06113
C03904_C03905
C05773_C19724
C06504_C19724
C21177_C21179
C21458_C21465
Related class
DB search
Reaction
R00021
R00093
R00114
R00253
R00256
R00257
R00269
R00348
R00482
R00483
R00485
R00573
R00575
R00578
R00768
R00986
R01072
R01231
R01579
R01716
R01922
R02273
R02540
R02622
R02938
R03096
R03180
R03804
R03905
R04212
R04341
R04463
R04558
R05224
R05225
R05815
R07456
R08244
R08855
R08956
R09195
R09537
R09598
R09599
R09648
R10089
R11209
R11515
R11559
R11560
Enzyme
1.4.1.13
1.4.1.14
1.4.7.1
2.4.2.14
2.6.1.16
2.6.1.85
2.6.1.86
2.6.1.123
3.5.1.1
3.5.1.2
3.5.1.3
3.5.1.4
3.5.1.30
3.5.1.35
3.5.1.38
3.5.1.43
3.5.1.44
3.5.1.50
3.5.1.73
3.5.1.99
3.5.1.100
3.5.1.111
3.5.1.119
3.5.1.121
3.5.1.122
3.5.1.-
3.5.5.4
4.1.3.27
4.3.2.10
4.3.3.6
6.3.1.1
6.3.1.2
6.3.1.4
6.3.4.2
6.3.5.1
6.3.5.2
6.3.5.3
6.3.5.4
6.3.5.5
6.3.5.6
6.3.5.7
6.3.5.9
6.3.5.10
6.3.5.11
6.3.5.13
6.3.5.-
» show all
Pathway
rn00250
Alanine, aspartate and glutamate metabolism
rn00253
Tetracycline biosynthesis
rn00310
Lysine degradation
rn00330
Arginine and proline metabolism
rn00360
Phenylalanine metabolism
rn00380
Tryptophan metabolism
rn00460
Cyanoamino acid metabolism
rn00470
D-Amino acid metabolism
rn00630
Glyoxylate and dicarboxylate metabolism
rn00643
Styrene degradation
rn00910
Nitrogen metabolism
rn00970
Aminoacyl-tRNA biosynthesis
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
rn01120
Microbial metabolism in diverse environments
rn01230
Biosynthesis of amino acids
RModule
RM031
Oxime to acetate conversion
Orthology
K00264
glutamate synthase (NADH) [EC:
1.4.1.14
]
K00265
glutamate synthase (NADPH) large chain [EC:
1.4.1.13
]
K00266
glutamate synthase (NADPH) small chain [EC:
1.4.1.13
]
K00284
glutamate synthase (ferredoxin) [EC:
1.4.7.1
]
K00764
amidophosphoribosyltransferase [EC:
2.4.2.14
]
K00820
glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:
2.6.1.16
]
K01424
L-asparaginase [EC:
3.5.1.1
]
K01425
glutaminase [EC:
3.5.1.2
]
K01426
amidase [EC:
3.5.1.4
]
K01506
5-aminopentanamidase [EC:
3.5.1.30
]
K01656
anthranilate synthase / indole-3-glycerol phosphate synthase [EC:
4.1.3.27
4.1.1.48
]
K01657
anthranilate synthase component I [EC:
4.1.3.27
]
K01658
anthranilate synthase component II [EC:
4.1.3.27
]
K01663
imidazole glycerol-phosphate synthase [EC:
4.3.2.10
]
K01664
para-aminobenzoate synthetase component II [EC:
2.6.1.85
]
K01665
para-aminobenzoate synthetase component I [EC:
2.6.1.85
]
K01914
aspartate--ammonia ligase [EC:
6.3.1.1
]
K01915
glutamine synthetase [EC:
6.3.1.2
]
K01937
CTP synthase [EC:
6.3.4.2
]
K01950
NAD+ synthase (glutamine-hydrolysing) [EC:
6.3.5.1
]
K01951
GMP synthase (glutamine-hydrolysing) [EC:
6.3.5.2
]
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
K01953
asparagine synthase (glutamine-hydrolysing) [EC:
6.3.5.4
]
K01954
carbamoyl-phosphate synthase [EC:
6.3.5.5
]
K01955
carbamoyl-phosphate synthase large subunit [EC:
6.3.5.5
]
K01956
carbamoyl-phosphate synthase small subunit [EC:
6.3.5.5
]
K02224
cobyrinic acid a,c-diamide synthase [EC:
6.3.5.9
6.3.5.11
]
K02232
adenosylcobyric acid synthase [EC:
6.3.5.10
]
K02433
aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:
6.3.5.6
6.3.5.7
]
K02434
aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:
6.3.5.6
6.3.5.7
]
K02435
aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:
6.3.5.6
6.3.5.7
]
K02500
imidazole glycerol-phosphate synthase subunit HisF [EC:
4.3.2.10
]
K02501
imidazole glycerol-phosphate synthase subunit HisH [EC:
4.3.2.10
]
K03330
glutamyl-tRNA(Gln) amidotransferase subunit E [EC:
6.3.5.7
]
K03342
para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:
2.6.1.85
4.1.3.38
]
K03865
glutamyl-tRNA(Gln) amidotransferase subunit F [EC:
6.3.5.7
]
K05597
glutamin-(asparagin-)ase [EC:
3.5.1.38
]
K06215
pyridoxal 5'-phosphate synthase pdxS subunit [EC:
4.3.3.6
]
K08590
2-oxoglutaramate amidase [EC:
3.5.1.111
]
K08681
pyridoxal 5'-phosphate synthase pdxT subunit [EC:
4.3.3.6
]
K09482
glutamyl-tRNA(Gln) amidotransferase subunit D [EC:
6.3.5.7
]
K11540
carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:
6.3.5.5
2.1.3.2
3.5.2.3
]
K11541
carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:
6.3.5.5
2.1.3.2
]
K13051
L-asparaginase / beta-aspartyl-peptidase [EC:
3.5.1.1
3.4.19.5
]
K13063
2-amino-4-deoxychorismate synthase [EC:
2.6.1.86
]
K13497
anthranilate synthase/phosphoribosyltransferase [EC:
4.1.3.27
2.4.2.18
]
K13501
anthranilate synthase / indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase [EC:
4.1.3.27
4.1.1.48
5.3.1.24
]
K13503
anthranilate synthase [EC:
4.1.3.27
]
K13566
omega-amidase [EC:
3.5.1.3
]
K13950
para-aminobenzoate synthetase [EC:
2.6.1.85
]
K14244
amidotransferase [EC:6.3.5.-]
K14662
protein N-terminal asparagine amidohydrolase [EC:
3.5.1.121
]
K20159
2-amino-4-deoxychorismate synthase [EC:
2.6.1.86
]
K21175
2-amino-4-deoxychorismate synthase, glutamine amidotransferase component [EC:
2.6.1.86
]
K21286
protein N-terminal glutamine amidohydrolase [EC:
3.5.1.122
]
K21801
indoleacetamide hydrolase [EC:3.5.1.-]
K23264
phosphoribosylformylglycinamidine synthase subunit PurS [EC:
6.3.5.3
]
K23265
phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:
6.3.5.3
3.5.1.2
]
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
K23270
phosphoribosylformylglycinamidine synthase subunit PurSL [EC:
6.3.5.3
]
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integrated database retrieval system
