KEGG   PATHWAY: acs04070
Entry
acs04070                    Pathway                                
Name
Phosphatidylinositol signaling system - Anolis carolinensis (green anole)
Class
Environmental Information Processing; Signal transduction
Pathway map
acs04070  Phosphatidylinositol signaling system
acs04070

Organism
Anolis carolinensis (green anole) [GN:acs]
Gene
100554829  pi4ka; phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
100566060  pi4kb; phosphatidylinositol 4-kinase beta [KO:K19801] [EC:2.7.1.67]
100564869  pi4k2b; phosphatidylinositol 4-kinase type 2 beta [KO:K13711] [EC:2.7.1.67]
100566736  pi4k2a; phosphatidylinositol 4-kinase type 2 alpha [KO:K13711] [EC:2.7.1.67]
100558693  sacm1l; SAC1 suppressor of actin mutations 1-like (yeast) [KO:K21797] [EC:3.1.3.-]
100563460  inpp5f; inositol polyphosphate-5-phosphatase F [KO:K21798] [EC:3.1.3.-]
100553211  pip5k1a; phosphatidylinositol-4-phosphate 5-kinase type 1 alpha [KO:K00889] [EC:2.7.1.68]
100564566  pip5k1b; phosphatidylinositol-4-phosphate 5-kinase type 1 beta [KO:K00889] [EC:2.7.1.68]
103282473  phosphatidylinositol 4-phosphate 5-kinase type-1 gamma-like [KO:K00889] [EC:2.7.1.68]
100555494  inpp5b; inositol polyphosphate-5-phosphatase B [KO:K01099] [EC:3.1.3.36]
100563751  ocrl; OCRL, inositol polyphosphate-5-phosphatase [KO:K01099] [EC:3.1.3.36]
100555178  inpp5e; inositol polyphosphate-5-phosphatase E [KO:K20278] [EC:3.1.3.36]
100562404  synj2; synaptojanin 2 [KO:K20279] [EC:3.1.3.36]
100567389  synj1; synaptojanin 1 [KO:K20279] [EC:3.1.3.36]
100567364  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
100568252  pik3cd; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [KO:K00922] [EC:2.7.1.153]
100567254  pik3cb; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [KO:K00922] [EC:2.7.1.153]
100562345  pik3ca; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [KO:K00922] [EC:2.7.1.153]
100556883  pik3r1; phosphoinositide-3-kinase regulatory subunit 1 [KO:K02649]
100555182  pik3r2; phosphoinositide-3-kinase regulatory subunit 2 [KO:K02649]
100554618  pik3r3; phosphoinositide-3-kinase regulatory subunit 3 [KO:K02649]
100552870  pten; phosphatase and tensin homolog [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
100561031  inpp5d; inositol polyphosphate-5-phosphatase D [KO:K03084] [EC:3.1.3.86]
100556812  inppl1; inositol polyphosphate phosphatase like 1 [KO:K15909] [EC:3.1.3.86]
100551799  inpp4a; inositol polyphosphate-4-phosphatase type I A [KO:K01109] [EC:3.1.3.66]
100567592  inpp4b; inositol polyphosphate-4-phosphatase type II B [KO:K01109] [EC:3.1.3.66]
100566486  pikfyve; phosphoinositide kinase, FYVE-type zinc finger containing [KO:K00921] [EC:2.7.1.150]
100564867  mtm1; myotubularin 1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
100556577  mtmr2; myotubularin related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
100564667  mtmr1; myotubularin related protein 1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
100567629  myotubularin-related protein 4 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
100553091  mtmr8; myotubularin related protein 8 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
100554881  mtmr7; myotubularin related protein 7 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
100556135  mtmr6; myotubularin related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
100554543  mtmr14; myotubularin related protein 14 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
100567083  pip4k2c; phosphatidylinositol-5-phosphate 4-kinase type 2 gamma [KO:K00920] [EC:2.7.1.149]
100552595  pip4k2a; phosphatidylinositol-5-phosphate 4-kinase type 2 alpha [KO:K00920] [EC:2.7.1.149]
100557825  pip4k2b; phosphatidylinositol-5-phosphate 4-kinase type 2 beta [KO:K00920] [EC:2.7.1.149]
100567084  tmem55b; transmembrane protein 55B [KO:K13084] [EC:3.1.3.78]
100556773  tmem55a; transmembrane protein 55A [KO:K13084] [EC:3.1.3.78]
100552043  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
100557407  pik3c2a; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha [KO:K00923] [EC:2.7.1.154]
100567393  pik3c2b; phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta [KO:K00923] [EC:2.7.1.154]
100551754  plcb2; phospholipase C beta 2 [KO:K05858] [EC:3.1.4.11]
100567752  plcb3; phospholipase C beta 3 [KO:K05858] [EC:3.1.4.11]
100560758  plcb4; phospholipase C beta 4 [KO:K05858] [EC:3.1.4.11]
100566853  plcb1; phospholipase C beta 1 [KO:K05858] [EC:3.1.4.11]
100552636  plcd4; phospholipase C delta 4 [KO:K05857] [EC:3.1.4.11]
100559401  plcd3; phospholipase C delta 3 [KO:K05857] [EC:3.1.4.11]
100567266  plcd1; phospholipase C delta 1 [KO:K05857] [EC:3.1.4.11]
100552081  plce1; phospholipase C epsilon 1 [KO:K05860] [EC:3.1.4.11]
100559347  plcg1; phospholipase C gamma 1 [KO:K01116] [EC:3.1.4.11]
100566976  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
100566814  plcg2; phospholipase C gamma 2 [KO:K05859] [EC:3.1.4.11]
100555994  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [KO:K05861] [EC:3.1.4.11]
100558870  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [KO:K05861] [EC:3.1.4.11]
100560539  ipmk; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
100554212  itpkb; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
100566754  itpkc; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
100564166  itpka; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
100557009  inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
100552188  inpp5a; inositol polyphosphate-5-phosphatase A [KO:K01106] [EC:3.1.3.56]
100566274  itpk1; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
100554094  ippk; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
100566479  ip6k2; inositol hexakisphosphate kinase 2 [KO:K07756] [EC:2.7.4.21]
100558855  ip6k1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
100564056  ip6k3; inositol hexakisphosphate kinase 3 [KO:K07756] [EC:2.7.4.21]
100568184  ppip5k2; diphosphoinositol pentakisphosphate kinase 2 [KO:K13024] [EC:2.7.4.24]
100554395  ppip5k1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 [KO:K13024] [EC:2.7.4.24]
100556887  inpp1; inositol polyphosphate-1-phosphatase [KO:K01107] [EC:3.1.3.57]
100554351  impa1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
100556213  impad1; inositol monophosphatase domain containing 1 [KO:K15759] [EC:3.1.3.7]
100567404  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
100555149  dgka; diacylglycerol kinase alpha [KO:K00901] [EC:2.7.1.107]
100561310  dgkq; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
100556056  dgkb; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
100560932  dgki; diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
100562316  dgkk; diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
100553220  dgkz; diacylglycerol kinase zeta [KO:K00901] [EC:2.7.1.107]
100557486  dgkg; diacylglycerol kinase gamma [KO:K00901] [EC:2.7.1.107]
100551725  dgkh; diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
100561428  dgkd; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
100553354  cds2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
100566366  cds1; CDP-diacylglycerol synthase 1 [KO:K00981] [EC:2.7.7.41]
100565327  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
100568038  itpr1; inositol 1,4,5-trisphosphate receptor type 1 [KO:K04958]
100567982  itpr2; inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
100564450  itpr3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
100554897  prkca; protein kinase C alpha [KO:K02677] [EC:2.7.11.13]
103281881  protein kinase C beta type [KO:K19662] [EC:2.7.11.13]
100565082  protein kinase C beta type [KO:K19662] [EC:2.7.11.13]
100559682  prkcg; protein kinase C gamma [KO:K19663] [EC:2.7.11.13]
107983676  calmodulin-like protein 5 [KO:K02183]
100565534  calm3; calmodulin 3 [KO:K02183]
100552424  calmodulin [KO:K02183]
100562594  calm1; calmodulin 1 [KO:K02183]
100560656  calmodulin [KO:K02183]
100551861  calm2; calmodulin 2 [KO:K02183]
100563169  calml4; calmodulin like 4 [KO:K02183]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
acs04020  Calcium signaling pathway
acs04144  Endocytosis
acs04510  Focal adhesion
KO pathway
ko04070   
LinkDB

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