KEGG   PATHWAY: ath00230
Entry
ath00230                    Pathway                                
Name
Purine metabolism - Arabidopsis thaliana (thale cress)
Class
Metabolism; Nucleotide metabolism
Pathway map
ath00230  Purine metabolism
ath00230

Module
ath_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ath00230]
ath_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ath00230]
ath_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ath00230]
ath_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ath00230]
ath_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ath00230]
Other DBs
GO: 0006163 0042278
Organism
Arabidopsis thaliana (thale cress) [GN:ath]
Gene
AT4G24730  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like protein [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
AT2G04450  NUDT6; nudix hydrolase homolog 6 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
AT4G12720  NUDT7; MutT/nudix family protein [KO:K26956] [EC:3.6.1.13 3.6.1.22]
AT4G25434  NUDT10; nudix hydrolase homolog 10 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
AT5G47650  NUDT2; nudix hydrolase homolog 2 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
AT2G42070  NUDX23; nudix hydrolase homolog 23 [KO:K18453] [EC:3.6.1.13 3.6.1.18]
AT4G11980  NUDX14; nudix hydrolase homolog 14 [KO:K18447] [EC:3.6.1.21]
AT5G51820  PGM; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
AT1G23190  PGM3; Phosphoglucomutase/phosphomannomutase family protein [KO:K01835] [EC:5.4.2.2]
AT1G70730  PGM2; Phosphoglucomutase/phosphomannomutase family protein [KO:K01835] [EC:5.4.2.2]
AT2G44530  Phosphoribosyltransferase family protein [KO:K00948] [EC:2.7.6.1]
AT1G32380  PRS2; phosphoribosyl pyrophosphate (PRPP) synthase 2 [KO:K00948] [EC:2.7.6.1]
AT2G35390  Phosphoribosyltransferase family protein [KO:K00948] [EC:2.7.6.1]
AT4G34740  ASE2; GLN phosphoribosyl pyrophosphate amidotransferase 2 [KO:K00764] [EC:2.4.2.14]
AT2G16570  ASE1; GLN phosphoribosyl pyrophosphate amidotransferase 1 [KO:K00764] [EC:2.4.2.14]
AT4G38880  ASE3; GLN phosphoribosyl pyrophosphate amidotransferase 3 [KO:K00764] [EC:2.4.2.14]
AT1G09830  PUR2; Glycinamide ribonucleotide (GAR) synthetase [KO:K01945] [EC:6.3.4.13]
AT1G31220  Formyl transferase [KO:K00601] [EC:2.1.2.2]
AT1G74260  PUR4; purine biosynthesis 4 [KO:K01952] [EC:6.3.5.3]
AT3G55010  PUR5; phosphoribosylformylglycinamidine cyclo-ligase, chloroplast / phosphoribosyl-aminoimidazole synthetase / AIR synthase (PUR5) [KO:K01933] [EC:6.3.3.1]
AT2G37690  phosphoribosylaminoimidazole carboxylase, putative / AIR carboxylase [KO:K11808] [EC:4.1.1.21]
AT3G21110  PUR7; purin 7 [KO:K01923] [EC:6.3.2.6]
AT1G36280  L-Aspartase-like family protein [KO:K01756] [EC:4.3.2.2]
AT4G18440  L-Aspartase-like family protein [KO:K01756] [EC:4.3.2.2]
AT2G35040  AICARFT/IMPCHase bienzyme family protein [KO:K00602] [EC:2.1.2.3 3.5.4.10]
AT4G12440  APT4; adenine phosphoribosyl transferase 4 [KO:K00759] [EC:2.4.2.7]
AT5G11160  APT5; adenine phosphoribosyltransferase 5 [KO:K00759] [EC:2.4.2.7]
AT4G22570  APT3; adenine phosphoribosyl transferase 3 [KO:K00759] [EC:2.4.2.7]
AT1G80050  APT2; adenine phosphoribosyl transferase 2 [KO:K00759] [EC:2.4.2.7]
AT1G27450  APT1; adenine phosphoribosyl transferase 1 [KO:K00759] [EC:2.4.2.7]
AT1G72880  Survival protein SurE-like phosphatase/nucleotidase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
AT4G14930  Survival protein SurE-like phosphatase/nucleotidase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
AT1G71750  HGPT; Hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
AT1G16350  Aldolase-type TIM barrel family protein [KO:K00088] [EC:1.1.1.205]
AT1G79470  Aldolase-type TIM barrel family protein [KO:K00088] [EC:1.1.1.205]
AT4G23900  Nucleoside diphosphate kinase family protein [KO:K00940] [EC:2.7.4.6]
AT5G63310  NDPK2; nucleoside diphosphate kinase 2 [KO:K00940] [EC:2.7.4.6]
AT4G11010  NDPK3; nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
AT4G09320  NDPK1; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
AT1G14250  GDA1/CD39 nucleoside phosphatase family protein [KO:K01510] [EC:3.6.1.5]
AT1G14230  GDA1/CD39 nucleoside phosphatase family protein [KO:K01510] [EC:3.6.1.5]
AT1G14240  GDA1/CD39 nucleoside phosphatase family protein [KO:K01510] [EC:3.6.1.5]
AT2G02970  GDA1/CD39 nucleoside phosphatase family protein [KO:K01510] [EC:3.6.1.5]
AT3G04080  APY1; apyrase 1 [KO:K14641] [EC:3.6.1.5]
AT5G18280  APY2; apyrase 2 [KO:K14641] [EC:3.6.1.5]
AT4G13720  Inosine triphosphate pyrophosphatase family protein [KO:K01519] [EC:3.6.1.66]
AT4G34890  XDH1; xanthine dehydrogenase 1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
AT4G34900  XDH2; xanthine dehydrogenase 2 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
AT1G30110  NUDX25; nudix hydrolase homolog 25 [KO:K26955] [EC:3.6.1.17]
AT1G63660  GMP synthase (glutamine-hydrolyzing), putative / glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
AT3G06200  P-loop containing nucleoside triphosphate hydrolases superfamily protein [KO:K00942] [EC:2.7.4.8]
AT2G41880  GK-1; guanylate kinase 1 [KO:K00942] [EC:2.7.4.8]
AT3G57550  AGK2; guanylate kinase [KO:K00942] [EC:2.7.4.8]
AT2G21790  RNR1; ribonucleotide reductase 1 [KO:K10807] [EC:1.17.4.1]
AT3G27060  TSO2; Ferritin/ribonucleotide reductase-like family protein [KO:K10808] [EC:1.17.4.1]
AT3G23580  RNR2A; ribonucleotide reductase 2A [KO:K10808] [EC:1.17.4.1]
AT1G26160  Metal-dependent phosphohydrolase [KO:K07023] [EC:3.1.3.89]
AT2G23820  Metal-dependent phosphohydrolase [KO:K07023] [EC:3.1.3.89]
AT1G54130  RSH3; RELA/SPOT homolog 3 [KO:K00951] [EC:2.7.6.5]
AT3G17470  CRSH; Ca2+-activated RelA/spot-like protein [KO:K00951] [EC:2.7.6.5]
AT3G14050  RSH2; RELA/SPOT homolog 2 [KO:K00951] [EC:2.7.6.5]
AT4G02260  RSH1; RELA/SPOT homolog 1 [KO:K00951] [EC:2.7.6.5]
AT2G02220  PSKR1; phytosulfokin receptor 1 [KO:K27625] [EC:2.7.11.1 4.6.1.2]
AT3G57610  ADSS; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
AT2G38280  FAC1; AMP deaminase, putative / myoadenylate deaminase [KO:K01490] [EC:3.5.4.6]
AT5G03300  ADK2; adenosine kinase 2 [KO:K00856] [EC:2.7.1.20]
AT3G09820  ADK1; adenosine kinase 1 [KO:K00856] [EC:2.7.1.20]
AT5G47840  AMK2; adenosine monophosphate kinase [KO:K00939] [EC:2.7.4.3]
AT5G50370  Adenylate kinase family protein [KO:K00939] [EC:2.7.4.3]
AT5G63400  ADK1; adenylate kinase 1 [KO:K00939] [EC:2.7.4.3]
AT5G35170  adenylate kinase family protein [KO:K00939] [EC:2.7.4.3]
AT2G39270  P-loop containing nucleoside triphosphate hydrolases superfamily protein [KO:K00939] [EC:2.7.4.3]
AT2G37250  ADK; adenosine kinase [KO:K00939] [EC:2.7.4.3]
AT3G01820  P-loop containing nucleoside triphosphate hydrolases superfamily protein [KO:K00939] [EC:2.7.4.3]
AT5G60340  AAK6; P-loop containing nucleoside triphosphate hydrolases superfamily protein [KO:K18532] [EC:2.7.4.3]
AT5G66005  uncharacterized protein [KO:K06928] [EC:3.6.1.15]
AT4G29680  Alkaline-phosphatase-like family protein [KO:K01513] [EC:3.1.4.1 3.6.1.9]
AT5G58240  FHIT; FRAGILE HISTIDINE TRIAD [KO:K01522] [EC:3.6.1.29]
AT4G14680  APS3; Pseudouridine synthase/archaeosine transglycosylase-like family protein [KO:K13811] [EC:2.7.7.4 2.7.1.25]
AT3G22890  APS1; ATP sulfurylase 1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
AT1G19920  APS2; Pseudouridine synthase/archaeosine transglycosylase-like family protein [KO:K13811] [EC:2.7.7.4 2.7.1.25]
AT5G43780  APS4; Pseudouridine synthase/archaeosine transglycosylase-like family protein [KO:K13811] [EC:2.7.7.4 2.7.1.25]
AT5G67520  APK4; adenosine-5'-phosphosulfate (APS) kinase 4 [KO:K00860] [EC:2.7.1.25]
AT3G03900  APK3; adenosine-5'-phosphosulfate (APS) kinase 3 [KO:K00860] [EC:2.7.1.25]
AT2G14750  APK; APS kinase [KO:K00860] [EC:2.7.1.25]
AT4G39940  AKN2; APS-kinase 2 [KO:K00860] [EC:2.7.1.25]
AT2G26230  uricase / urate oxidase / nodulin 35 [KO:K00365] [EC:1.7.3.3]
AT5G58220  TTL; transthyretin-like protein [KO:K13484] [EC:3.5.2.17 4.1.1.97]
AT4G04955  ALN; allantoinase [KO:K01466] [EC:3.5.2.5]
AT4G20070  AAH; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
AT4G17050  UGLYAH; ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
AT5G43600  UAH; ureidoglycolate amidohydrolase [KO:K18151] [EC:3.5.1.116]
AT1G67550  URE; urease [KO:K01427] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ath00030  Pentose phosphate pathway
ath00220  Arginine biosynthesis
ath00250  Alanine, aspartate and glutamate metabolism
ath00260  Glycine, serine and threonine metabolism
ath00340  Histidine metabolism
ath00630  Glyoxylate and dicarboxylate metabolism
ath00730  Thiamine metabolism
ath00740  Riboflavin metabolism
ath00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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