KEGG   PATHWAY: cpic00830
Entry
cpic00830                   Pathway                                
Name
Retinol metabolism - Chrysemys picta (western painted turtle)
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
cpic00830  Retinol metabolism
cpic00830

Other DBs
GO: 0006776
Organism
Chrysemys picta (western painted turtle) [GN:cpic]
Gene
101934984  BCO1; beta,beta-carotene 15,15'-dioxygenase isoform X2 [KO:K00515] [EC:1.13.11.63]
101948149  alcohol dehydrogenase 1A [KO:K13951] [EC:1.1.1.1]
101952436  alcohol dehydrogenase 1A-like [KO:K13951] [EC:1.1.1.1]
101948797  all-trans-retinol dehydrogenase [NAD(+)] ADH4 [KO:K13980] [EC:1.1.1.1]
101949414  alcohol dehydrogenase class-3 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
101941293  DHRS3; short-chain dehydrogenase/reductase 3 isoform X1 [KO:K11146] [EC:1.1.1.300]
101953306  dehydrogenase/reductase SDR family member 4-like [KO:K11147] [EC:1.1.-.-]
101948380  dehydrogenase/reductase SDR family member 9 isoform X1 [KO:K11149] [EC:1.1.-.-]
101946488  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
101934658  RDH8; retinol dehydrogenase 8 isoform X2 [KO:K11150] [EC:1.1.1.-]
101953301  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
101936064  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
101943136  LOW QUALITY PROTEIN: retinol dehydrogenase 10-like [KO:K11151] [EC:1.1.1.-]
101952708  RDH10; retinol dehydrogenase 10 isoform X1 [KO:K11151] [EC:1.1.1.-]
101950060  retinol dehydrogenase 12 isoform X1 [KO:K11153] [EC:1.1.1.300]
101934621  SDR16C5; epidermal retinol dehydrogenase 2 [KO:K15734] [EC:1.1.1.105]
101952318  epidermal retinol dehydrogenase 2-like [KO:K15734] [EC:1.1.1.105]
103306704  17-beta-hydroxysteroid dehydrogenase type 6-like [KO:K13369] [EC:1.1.1.62 1.1.1.105 1.1.1.239]
101949409  LRAT; lecithin retinol acyltransferase [KO:K00678] [EC:2.3.1.135]
101951746  diacylglycerol O-acyltransferase 1-like isoform X2 [KO:K11155] [EC:2.3.1.20 2.3.1.75 2.3.1.76]
101950960  DGAT1; diacylglycerol O-acyltransferase 1 [KO:K11155] [EC:2.3.1.20 2.3.1.75 2.3.1.76]
101952890  PNPLA4; patatin-like phospholipase domain-containing protein 4 isoform X1 [KO:K11157] [EC:3.1.1.-]
101936194  RPE65; retinoid isomerohydrolase isoform X2 [KO:K11158] [EC:3.1.1.64 5.3.3.22]
101937595  RDH5; retinol dehydrogenase 5 isoform X1 [KO:K00061] [EC:1.1.1.315]
101949373  AOX1; aldehyde oxidase 1 [KO:K00157] [EC:1.2.3.1]
101949109  aldehyde oxidase-like [KO:K00157] [EC:1.2.3.1]
101933340  ALDH1A1; retinal dehydrogenase 1 [KO:K07249] [EC:1.2.1.36]
101943620  ALDH1A2; retinal dehydrogenase 2 [KO:K07249] [EC:1.2.1.36]
101946404  ALDH1A3; aldehyde dehydrogenase family 1 member A3 isoform X1 [KO:K07249] [EC:1.2.1.36]
101950326  cytochrome P450 26A1 [KO:K07437] [EC:1.14.14.-]
101953793  cytochrome P450 26B1 isoform X1 [KO:K12664] [EC:1.14.14.-]
101934998  cytochrome P450 26C1 [KO:K12665] [EC:1.14.14.-]
101950120  cytochrome P450 2C23-like [KO:K07413] [EC:1.14.14.1]
101945572  cytochrome P450 2C5-like [KO:K07413] [EC:1.14.14.1]
101944980  cytochrome P450 3A9-like isoform X1 [KO:K07424] [EC:1.14.14.1]
101945909  cytochrome P450 3A24-like isoform X1 [KO:K07424] [EC:1.14.14.1]
101951856  cytochrome P450 2W1-like [KO:K07423] [EC:1.14.14.-]
101946980  UDP-glucuronosyltransferase 2C1-like isoform X1 [KO:K00699] [EC:2.4.1.17]
101936446  UDP-glucuronosyltransferase 1A1-like isoform X2 [KO:K00699] [EC:2.4.1.17]
112060180  UDP-glucuronosyltransferase 1A1-like [KO:K00699] [EC:2.4.1.17]
101948187  RETSAT; all-trans-retinol 13,14-reductase [KO:K09516] [EC:1.3.99.23]
101937097  LOW QUALITY PROTEIN: all-trans-retinol 13,14-reductase-like [KO:K09516] [EC:1.3.99.23]
101935484  cytochrome P450 27C1 [KO:K17951] [EC:1.14.19.53]
Compound
C00376  Retinal
C00473  Retinol
C00777  Retinoate
C00778  Rhodopsin
C00899  11-cis-Retinol
C02075  Retinyl ester
C02094  beta-Carotene
C02110  11-cis-Retinal
C02588  Retinyl palmitate
C03455  11-cis-Retinyl palmitate
C05914  Bathorhodopsin
C05915  Lumirhodopsin
C05916  Metarhodopsin
C05917  Iodopsin
C11061  all-trans-Retinoyl-beta-glucuronide
C15492  all-trans-13,14-Dihydroretinol
C15493  9-cis-Retinoic acid
C16677  all-trans-4-Hydroxyretinoic acid
C16678  all-trans-4-Oxoretinoic acid
C16679  all-trans-18-Hydroxyretinoic acid
C16680  all-trans-5,6-Epoxyretinoic acid
C16681  9-cis-Retinal
C16682  9-cis-Retinol
C16683  4-Oxoretinol
C21797  all-trans-3,4-Didehydroretinol
Reference
PMID:16968212
  Authors
Travis GH, Golczak M, Moise AR, Palczewski K.
  Title
Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents.
  Journal
Annu Rev Pharmacol Toxicol 47:469-512 (2007)
DOI:10.1146/annurev.pharmtox.47.120505.105225
Reference
PMID:17618621
  Authors
Muniz A, Villazana-Espinoza ET, Hatch AL, Trevino SG, Allen DM, Tsin AT.
  Title
A novel cone visual cycle in the cone-dominated retina.
  Journal
Exp Eye Res 85:175-84 (2007)
DOI:10.1016/j.exer.2007.05.003
Reference
PMID:11093772
  Authors
Marill J, Cresteil T, Lanotte M, Chabot GG.
  Title
Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.
  Journal
Mol Pharmacol 58:1341-8 (2000)
DOI:10.1124/mol.58.6.1341
Reference
PMID:17893666
  Authors
Nezzar H, Chiambaretta F, Marceau G, Blanchon L, Faye B, Dechelotte P, Rigal D, Sapin V.
  Title
Molecular and metabolic retinoid pathways in the human ocular surface.
  Journal
Mol Vis 13:1641-50 (2007)
Reference
PMID:16688755
  Authors
Blomhoff R, Blomhoff HK.
  Title
Overview of retinoid metabolism and function.
  Journal
J Neurobiol 66:606-30 (2006)
DOI:10.1002/neu.20242
Reference
PMID:16428379
  Authors
Liden M, Eriksson U.
  Title
Understanding retinol metabolism: structure and function of retinol dehydrogenases.
  Journal
J Biol Chem 281:13001-4 (2006)
DOI:10.1074/jbc.R500027200
KO pathway
ko00830   
LinkDB

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