KEGG   PATHWAY: eee04070
Entry
eee04070                    Pathway                                
Name
Phosphatidylinositol signaling system - Electrophorus electricus (electric eel)
Class
Environmental Information Processing; Signal transduction
Pathway map
eee04070  Phosphatidylinositol signaling system
eee04070

Organism
Electrophorus electricus (electric eel) [GN:eee]
Gene
113567981  [KO:K02649]
113567997  [KO:K00981] [EC:2.7.7.41]
113568728  pik3ca; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
113569625  [KO:K07756] [EC:2.7.4.21]
113569838  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform X1 [KO:K00999] [EC:2.7.8.11]
113570316  pip4k2c; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
113570559  [KO:K00913] [EC:2.7.1.159 2.7.1.134]
113570991  [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
113571128  [KO:K02183]
113571340  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
113571589  calml6; calmodulin-like protein 6 isoform X1 [KO:K02183]
113571600  [KO:K05858] [EC:3.1.4.11]
113571726  [KO:K02183]
113571772  synj1; LOW QUALITY PROTEIN: synaptojanin-1 [KO:K20279] [EC:3.1.3.36]
113571983  [KO:K05857] [EC:3.1.4.11]
113571989  [KO:K01092] [EC:3.1.3.25]
113572052  pikfyve; 1-phosphatidylinositol 3-phosphate 5-kinase [KO:K00921] [EC:2.7.1.150]
113572365  ip6k1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
113572594  pi4kb; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
113572657  [KO:K05858] [EC:3.1.4.11]
113572658  [KO:K05858] [EC:3.1.4.11]
113572741  [KO:K02183]
113572806  [KO:K02183]
113572910  inpp5e; 72 kDa inositol polyphosphate 5-phosphatase isoform X1 [KO:K20278] [EC:3.1.3.36]
113573309  [KO:K00888] [EC:2.7.1.67]
113573543  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
113574015  [KO:K01109] [EC:3.1.3.66]
113574432  sacm1l; phosphatidylinositide phosphatase SAC1 [KO:K21797] [EC:3.1.3.-]
113574439  mtmr6; myotubularin-related protein 6 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
113574477  [KO:K00889] [EC:2.7.1.68]
113574801  impa2; inositol monophosphatase 2 isoform X1 [KO:K01092] [EC:3.1.3.25]
113574929  [KO:K13084] [EC:3.1.3.78]
113575194  [KO:K00911] [EC:2.7.1.127]
113575273  [KO:K00889] [EC:2.7.1.68]
113575317  [KO:K02677] [EC:2.7.11.13]
113575555  [KO:K00889] [EC:2.7.1.68]
113575697  ppip5k1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 [KO:K13024] [EC:2.7.4.24]
113575910  inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
113575938  [KO:K07756] [EC:2.7.4.21]
113575990  [KO:K04958]
113576605  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
113576623  pik3c2g; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
113576636  [KO:K00911] [EC:2.7.1.127]
113576685  calml4; calmodulin-like protein 4 [KO:K02183]
113576744  ppip5k2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X1 [KO:K13024] [EC:2.7.4.24]
113576897  [KO:K00915] [EC:2.7.1.140 2.7.1.151]
113577017  ipmk; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
113577091  dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
113577099  [KO:K00901] [EC:2.7.1.107]
113577174  plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1 [KO:K05859] [EC:3.1.4.11]
113577202  plcd4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
113577462  itpkc; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
113577556  [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
113577572  mtmr4; myotubularin-related protein 4 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
113578044  inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
113578302  [KO:K00901] [EC:2.7.1.107]
113578319  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
113578361  [KO:K00889] [EC:2.7.1.68]
113578627  [KO:K02183]
113578858  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
113579208  [KO:K18083] [EC:3.1.3.64 3.1.3.95]
113579468  pten; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
113579499  [KO:K05857] [EC:3.1.4.11]
113579729  [KO:K13024] [EC:2.7.4.24]
113580068  [KO:K00889] [EC:2.7.1.68]
113580599  ippk; inositol-pentakisphosphate 2-kinase isoform X1 [KO:K10572] [EC:2.7.1.158]
113580798  [KO:K18081] [EC:3.1.3.64 3.1.3.95]
113580799  mtm1; myotubularin isoform X1 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
113580901  [KO:K19662] [EC:2.7.11.13]
113580968  pip4p2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
113581076  itpr3; inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
113581223  plcd1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [KO:K05857] [EC:3.1.4.11]
113581289  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
113581550  mtmr14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
113581578  inppl1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 [KO:K15909] [EC:3.1.3.86]
113581716  [KO:K00920] [EC:2.7.1.149]
113582411  [KO:K01092] [EC:3.1.3.25]
113582441  [KO:K15909] [EC:3.1.3.86]
113582836  mtmr7; myotubularin-related protein 7 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
113583305  [KO:K00913] [EC:2.7.1.159 2.7.1.134]
113583416  [KO:K21797] [EC:3.1.3.-]
113584197  inpp5a; type I inositol 1,4,5-trisphosphate 5-phosphatase [KO:K01106] [EC:3.1.3.56]
113584489  [KO:K00901] [EC:2.7.1.107]
113584760  plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
113584921  pi4ka; phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
113584997  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
113585229  inpp5f; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
113585380  [KO:K00911] [EC:2.7.1.127]
113585611  [KO:K00901] [EC:2.7.1.107]
113585976  [KO:K00889] [EC:2.7.1.68]
113586011  [KO:K02183]
113586134  ocrl; inositol polyphosphate 5-phosphatase OCRL-1 isoform X1 [KO:K01099] [EC:3.1.3.36]
113586700  [KO:K01106] [EC:3.1.3.56]
113586837  [KO:K05857] [EC:3.1.4.11]
113587243  dgka; diacylglycerol kinase alpha [KO:K00901] [EC:2.7.1.107]
113588041  dgkq; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
113588232  pik3r1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
113588553  dgkd; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
113588699  inpp1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
113588773  [KO:K19662] [EC:2.7.11.13]
113588884  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
113588890  [KO:K05857] [EC:3.1.4.11]
113588959  pip4p1; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
113589054  [KO:K00920] [EC:2.7.1.149]
113589083  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
113589181  [KO:K05858] [EC:3.1.4.11]
113589364  cds1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
113589466  plcb4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
113590071  [KO:K18083] [EC:3.1.3.64 3.1.3.95]
113590399  [KO:K18081] [EC:3.1.3.64 3.1.3.95]
113590406  [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
113590571  [KO:K04959]
113590761  [KO:K19662] [EC:2.7.11.13]
113591089  inpp4a; type I inositol 3,4-bisphosphate 4-phosphatase [KO:K01109] [EC:3.1.3.66]
113591196  pi4k2a; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
113591392  impad1; inositol monophosphatase 3 [KO:K15759] [EC:3.1.3.7]
113591476  pi4k2b; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
113591760  inpp4b; type II inositol 3,4-bisphosphate 4-phosphatase [KO:K01109] [EC:3.1.3.66]
113592259  mtmr2; myotubularin-related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
eee04020  Calcium signaling pathway
eee04144  Endocytosis
eee04510  Focal adhesion
KO pathway
ko04070   

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