KEGG   PATHWAY: esp03083
Entry
esp03083                    Pathway                                
Name
Polycomb repressive complex - Etheostoma spectabile (orangethroat darter)
Class
Genetic Information Processing; Chromosome
Pathway map
esp03083  Polycomb repressive complex
esp03083

Organism
Etheostoma spectabile (orangethroat darter) [GN:esp]
Gene
116669911  [KO:K09201]
116670042  [KO:K06067] [EC:3.5.1.98]
116670181  [KO:K11465]
116670242  [KO:K10752]
116670336  [KO:K11471]
116670481  [KO:K04453]
116670887  [KO:K26253]
116670919  [KO:K11454]
116670926  [KO:K24387]
116671037  [KO:K09404]
116671068  [KO:K04498] [EC:2.3.1.48]
116671317  [KO:K11805]
116671549  [KO:K06689] [EC:2.3.2.23]
116672267  bmi1; polycomb complex protein BMI-1 [KO:K11459]
116673237  [KO:K17452]
116673394  [KO:K11468]
116673494  sfmbt2; scm-like with four MBT domains protein 2 isoform X1 [KO:K26269]
116673877  eed; polycomb protein EED [KO:K11462]
116674008  mbd5; methyl-CpG-binding domain protein 5 [KO:K23219]
116674611  [KO:K11456]
116677445  [KO:K10752]
116677843  [KO:K11463]
116679291  [KO:K11458]
116679545  [KO:K06689] [EC:2.3.2.23]
116685966  [KO:K06689] [EC:2.3.2.23]
116686079  [KO:K06689] [EC:2.3.2.23]
116687058  usp16; ubiquitin carboxyl-terminal hydrolase 16 [KO:K11844] [EC:3.4.19.12]
116688055  phc2; polyhomeotic-like protein 2 isoform X1 [KO:K11457]
116688219  bap1; ubiquitin carboxyl-terminal hydrolase BAP1 [KO:K08588] [EC:3.4.19.12]
116688555  [KO:K14966]
116688665  sfmbt1; scm-like with four MBT domains protein 1 isoform X1 [KO:K26269]
116688677  rybp; RING1 and YY1-binding protein [KO:K11469]
116689290  [KO:K06689] [EC:2.3.2.23]
116689466  fbrsl1; fibrosin-1-like protein isoform X1 [KO:K26254]
116690797  scmh1; polycomb protein SCMH1 isoform X1 [KO:K11461]
116690888  [KO:K11467]
116691067  [KO:K03115]
116691219  [KO:K11456]
116691417  [KO:K24387]
116691618  tex10; testis-expressed protein 10 isoform X1 [KO:K14827]
116691629  usp45; ubiquitin carboxyl-terminal hydrolase 45 isoform X1 [KO:K11844] [EC:3.4.19.12]
116691928  ring1; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RING1 [KO:K10695] [EC:2.3.2.27]
116692549  [KO:K26585]
116692843  [KO:K24387]
116693083  [KO:K11471]
116694107  yaf2; YY1-associated factor 2 [KO:K11468]
116694181  [KO:K17452]
116694899  pcgf2; polycomb group RING finger protein 2 [KO:K11460]
116695237  [KO:K11463]
116696044  scml2; sex comb on midleg-like protein 2 isoform X1 [KO:K11465]
116696316  kdm2a; lysine-specific demethylase 2A [KO:K10276] [EC:1.14.11.27]
116696404  pcgf1; polycomb group RING finger protein 1 isoform X1 [KO:K11487]
116696423  ogt; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1 [KO:K09667] [EC:2.4.1.255]
116696698  bcorl1; BCL-6 corepressor-like protein 1 [KO:K26199]
116696709  foxk1; forkhead box protein K1 isoform X1 [KO:K09404]
116696937  pcgf3; polycomb group RING finger protein 3 isoform X1 [KO:K11488]
116697763  tfdp1; transcription factor Dp-1 [KO:K04683]
116698418  bcor; LOW QUALITY PROTEIN: BCL-6 corepressor [KO:K23215]
116698705  phc3; LOW QUALITY PROTEIN: polyhomeotic-like protein 3 [KO:K11458]
116699339  mtf2; metal-response element-binding transcription factor 2 isoform X1 [KO:K11485]
116699655  [KO:K10695] [EC:2.3.2.27]
116700182  skp1; LOW QUALITY PROTEIN: S-phase kinase-associated protein 1 [KO:K03094]
116700506  auts2; autism susceptibility gene 2 protein isoform X1 [KO:K23214]
116701353  jarid2; protein Jumonji isoform X1 [KO:K11478]
116701431  [KO:K11456]
116701444  [KO:K06067] [EC:3.5.1.98]
116701454  cbx3; chromobox protein homolog 3 isoform X1 [KO:K11586]
116702024  [KO:K03115]
116702118  cbx4; E3 SUMO-protein ligase CBX4 [KO:K11452] [EC:2.3.2.-]
116702211  [KO:K10752]
116702481  ezh1; histone-lysine N-methyltransferase EZH1 isoform X1 [KO:K17451] [EC:2.1.1.356]
116702512  [KO:K11452] [EC:2.3.2.-]
116702521  [KO:K11455]
116702553  [KO:K10752]
116702633  crebbp; CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
116702661  [KO:K11805]
116702788  [KO:K04498] [EC:2.3.1.48]
116702945  [KO:K09404]
116702950  [KO:K11463]
116703103  [KO:K11454]
116703196  usp7; ubiquitin carboxyl-terminal hydrolase 7 [KO:K11838] [EC:3.4.19.12]
116703223  [KO:K11451]
116704051  [KO:K10276] [EC:1.14.11.27]
116704101  wdr5; WD repeat-containing protein 5 [KO:K14963]
116704627  [KO:K06689] [EC:2.3.2.23]
116705010  pcgf5; polycomb group RING finger protein 5 isoform X1 [KO:K11489]
116705504  [KO:K06689] [EC:2.3.2.23]
116705505  [KO:K09404]
116705739  pcgf6; polycomb group RING finger protein 6 [KO:K11470]
116705772  [KO:K11455]
116706070  max; protein max isoform X1 [KO:K04453]
116706113  [KO:K09390]
116706247  [KO:K23399]
116706409  [KO:K09201]
116706615  [KO:K04498] [EC:2.3.1.48]
Reference
PMID:21881606
  Authors
Richly H, Aloia L, Di Croce L
  Title
Roles of the Polycomb group proteins in stem cells and cancer.
  Journal
Cell Death Dis 2:e204 (2011)
DOI:10.1038/cddis.2011.84
Reference
PMID:28202673
  Authors
Chittock EC, Latwiel S, Miller TC, Muller CW
  Title
Molecular architecture of polycomb repressive complexes.
  Journal
Biochem Soc Trans 45:193-205 (2017)
DOI:10.1042/BST20160173
Reference
PMID:33202645
  Authors
Geng Z, Gao Z
  Title
Mammalian PRC1 Complexes: Compositional Complexity and Diverse Molecular Mechanisms.
  Journal
Int J Mol Sci 21:ijms21228594 (2020)
DOI:10.3390/ijms21228594
Reference
PMID:35681061
  Authors
Kim JJ, Kingston RE
  Title
Context-specific Polycomb mechanisms in development.
  Journal
Nat Rev Genet 23:680-695 (2022)
DOI:10.1038/s41576-022-00499-0
Reference
PMID:36076977
  Authors
Dong GJ, Xu JL, Qi YR, Yuan ZQ, Zhao W
  Title
Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer.
  Journal
Int J Mol Sci 23:ijms23179574 (2022)
DOI:10.3390/ijms23179574
Reference
PMID:37086328
  Authors
Ryan CW, Peirent ER, Regan SL, Guxholli A, Bielas SL
  Title
H2A monoubiquitination: insights from human genetics and animal models.
  Journal
Hum Genet 143:511-527 (2024)
DOI:10.1007/s00439-023-02557-x
KO pathway
ko03083   

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