Homo sapiens (human): 2740 Help Entry 2740              CDS       T01001                                  Gene name GLP1R, GLP-1, GLP-1-R, GLP-1R Definition (RefSeq) glucagon like peptide 1 receptor   KO K04581   glucagon-like peptide 1 receptor Organism hsa  Homo sapiens (human) Pathway hsa04024   cAMP signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04911   Insulin secretion Drug target Albiglutide:  D08843 Avexitide:  D11418 Avexitide acetate:  D11419 Beinaglutide:  D11924 Danuglipron (DG03125):  D11910 D11911 Dulaglutide:  D09889<JP/US> Efpeglenatide:  D11947 Exenatide:  D04121<JP/US> Insulin degludec and liraglutide:  D11567<JP/US> Insulin glargin and lixisenatide:  D11034<JP/US> Liraglutide:  D06404<JP/US> Lixisenatide:  D09729<JP/US> Pegapamodutide:  D10970 Semaglutide:  D10025<JP/US> Taspoglutide:  D09723 Tirzepatide:  D11360 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04024 cAMP signaling pathway     2740 (GLP1R)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     2740 (GLP1R)  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     2740 (GLP1R)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     2740 (GLP1R) G protein-coupled receptors [BR:hsa04030]  Secretin receptor family   Pancreatic peptide    Glucagon     2740 (GLP1R) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_2 HRM Motif Other DBs NCBI-GeneID:  2740 NCBI-ProteinID:  NP_002053 OMIM:  138032 HGNC:  4324 Ensembl:  ENSG00000112164 Vega:  OTTHUMG00000014638 Pharos:  P43220(Tclin) UniProt:  P43220 A0A142FHB8 LinkDB All DBs Structure PDB:  5OTU 4ZGM 5OTT 5OTV 5OTX 5E94 5OTW 3IOL 3C5T 3C59 6GB1 6B3J 5NX2 Thumbnails Position 6p21.2 AA seq 463 aa AA seqDB search MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDL FCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPW RDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIH LNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAAN YYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRN SNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLL GTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERW RLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS NT seq 1392 nt NT seq  +upstreamnt  +downstreamnt atggccggcgcccccggcccgctgcgccttgcgctgctgctgctcgggatggtgggcagg gccggcccccgcccccagggtgccactgtgtccctctgggagacggtgcagaaatggcga gaataccgacgccagtgccagcgctccctgactgaggatccacctcctgccacagacttg ttctgcaaccggaccttcgatgaatacgcctgctggccagatggggagccaggctcgttc gtgaatgtcagctgcccctggtacctgccctgggccagcagtgtgccgcagggccacgtg taccggttctgcacagctgaaggcctctggctgcagaaggacaactccagcctgccctgg agggacttgtcggagtgcgaggagtccaagcgaggggaaagaagctccccggaggagcag ctcctgttcctctacatcatctacacggtgggctacgcactctccttctctgctctggtt atcgcctctgcgatcctcctcggcttcagacacctgcactgcaccaggaactacatccac ctgaacctgtttgcatccttcatcctgcgagcattgtccgtcttcatcaaggacgcagcc ctgaagtggatgtatagcacagccgcccagcagcaccagtgggatgggctcctctcctac caggactctctgagctgccgcctggtgtttctgctcatgcagtactgtgtggcggccaat tactactggctcttggtggagggcgtgtacctgtacacactgctggccttctcggtctta tctgagcaatggatcttcaggctctacgtgagcataggctggggtgttcccctgctgttt gttgtcccctggggcattgtcaagtacctctatgaggacgagggctgctggaccaggaac tccaacatgaactactggctcattatccggctgcccattctctttgccattggggtgaac ttcctcatctttgttcgggtcatctgcatcgtggtatccaaactgaaggccaatctcatg tgcaagacagacatcaaatgcagacttgccaagtccacgctgacactcatccccctgctg gggactcatgaggtcatctttgcctttgtgatggacgagcacgcccgggggaccctgcgc ttcatcaagctgtttacagagctctccttcacctccttccaggggctgatggtggccata ttatactgctttgtcaacaatgaggtccagctggaatttcggaagagctgggagcgctgg cggcttgagcacttgcacatccagagggacagcagcatgaagcccctcaagtgtcccacc agcagcctgagcagtggagccacggcgggcagcagcatgtacacagccacttgccaggcc tcctgcagctga

Homo sapiens (human): 9340 Help Entry 9340              CDS       T01001                                  Gene name GLP2R Definition (RefSeq) glucagon like peptide 2 receptor   KO K04582   glucagon-like peptide 2 receptor Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction Drug target Glepaglutide:  D11337 Teduglutide:  D06053<JP/US> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     9340 (GLP2R)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     9340 (GLP2R) G protein-coupled receptors [BR:hsa04030]  Secretin receptor family   Pancreatic peptide    Glucagon     9340 (GLP2R) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_2 HRM Motif Other DBs NCBI-GeneID:  9340 NCBI-ProteinID:  NP_004237 OMIM:  603659 HGNC:  4325 Ensembl:  ENSG00000065325 Vega:  OTTHUMG00000130269 Pharos:  O95838(Tclin) UniProt:  O95838 A0A384MTS7 B2RAN4 LinkDB All DBs Position 17p13.1 AA seq 553 aa AA seqDB search MKLGSSRAGPGRGSAGLLPGVHELPMGIPAPWGTSPLSFHRKCSLWAPGRPFLTLVLLVS IKQVTGSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPS YLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQL MYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYS KRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLW PRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLK ILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFI QLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLARHSGCRACVLGKDFRFLGKCPKK LSEGDGAEKLRKLQPSLNSGRLLHLAMRGLGELGAQPQQDHARWPRGSSLSECSEGDVTM ANTMEEILEESEI NT seq 1662 nt NT seq  +upstreamnt  +downstreamnt atgaagctgggatcgagcagggcagggcctgggagaggaagcgcgggactcctgcctggc gtccacgagctgcccatgggcatccctgccccctgggggaccagtcctctctccttccac aggaagtgctctctctgggcccctgggaggcccttcctcactctggtcctgctggtttcc atcaagcaagttacaggatccctccttgaggaaacgactcggaagtgggctcagtacaaa caggcatgtctgagagacttactcaaggaaccttctggcatattttgtaacgggacattt gatcagtacgtgtgttggcctcattcttctcctggaaatgtctctgtaccctgcccttca tacttaccttggtggagtgaagagagctcaggaagggcctacagacactgcttggctcag gggacttggcagacgatagagaacgccacggatatttggcaggatgactccgaatgctcc gagaaccacagcttcaagcaaaacgtggatcgttatgccttgctgtcaaccttgcagctg atgtacaccgtgggatactccttctctcttatctccctcttcctggctctcaccctcctc ttgtttcttcgaaaactccactgcacgcgcaactacatccacatgaacttgtttgcttct ttcatcctgagaaccctggctgtactggtgaaggacgtcgtcttctacaactcttactcc aagaggcctgacaatgagaatgggtggatgtcctacctgtcagagatgtccacctcctgc cgctcagtccaggttctcttgcattactttgtgggtgccaattacttatggctgctggtt gaaggcctctacctccacacgctgctggagcccacagtgcttcctgagaggcggctgtgg cccagatacctgctgttgggttgggccttccctgtgctatttgttgtaccctggggtttc gcccgtgcacacctggagaacacagggtgctggacaacaaatgggaataagaaaatctgg tggatcatccgaggacccatgatgctctgtgtaacagtcaatttcttcatcttcctgaaa attctcaagcttctcatttctaagctcaaagctcatcaaatgtgcttcagagattataaa tacagattggcaaaatcaacactggtcctcattcctttattgggcgttcatgagatcctc ttctctttcatcactgatgatcaagttgaaggatttgcaaaacttatacgacttttcatt cagttgacactgagctcctttcatgggttcctggtggccttgcagtatggttttgccaat ggagaggtgaaggctgagctgcggaaatactgggtccgcttcttgctagcccgccactca ggctgcagagcctgtgtcctggggaaggacttccggttcctaggaaaatgtcccaagaag ctctcggaaggagatggcgctgagaagcttcggaagctgcagccctcacttaacagtggg cggctcctacatctagccatgcgaggtcttggggagctgggcgcccagccccaacaggac catgcacgctggccccggggcagcagcctgtccgagtgcagtgagggggatgtcaccatg gccaacaccatggaggagattctggaagagagtgagatctag

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