KEGG   PATHWAY: ko00340
Entry
ko00340                     Pathway                                
Name
Histidine metabolism
Class
Metabolism; Amino acid metabolism
Pathway map
ko00340  Histidine metabolism
ko00340

Module
M00026  Histidine biosynthesis, PRPP => histidine [PATH:ko00340]
M00045  Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:ko00340]
Drug
D02922  Amodiaquine (USP/INN)
Other DBs
GO: 0006547
Orthology
K00765  ATP phosphoribosyltransferase [EC:2.4.2.17]
K02502  ATP phosphoribosyltransferase regulatory subunit
K01523  phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
K01496  phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
K11755  phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31]
K14152  phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]
K01814  phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
K24017  phosphoribosyl isomerase A [EC:5.3.1.16 5.3.1.24]
K02501  imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
K02500  imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
K01663  imidazole glycerol-phosphate synthase [EC:4.3.2.10]
K01693  imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
K01089  imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase [EC:4.2.1.19 3.1.3.15]
K00817  histidinol-phosphate aminotransferase [EC:2.6.1.9]
K05602  histidinol-phosphatase [EC:3.1.3.15]
K04486  histidinol-phosphatase (PHP family) [EC:3.1.3.15]
K18649  inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase [EC:3.1.3.25 3.1.3.93 3.1.3.15]
K00013  histidinol dehydrogenase [EC:1.1.1.23]
K01745  histidine ammonia-lyase [EC:4.3.1.3]
K01712  urocanate hydratase [EC:4.2.1.49]
K01468  imidazolonepropionase [EC:3.5.2.7]
K01479  formiminoglutamase [EC:3.5.3.8]
K00603  glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2]
K13990  glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4]
K05603  formimidoylglutamate deiminase [EC:3.5.3.13]
K01458  N-formylglutamate deformylase [EC:3.5.1.68]
K17363  urocanate reductase [EC:1.3.99.33]
K01590  histidine decarboxylase [EC:4.1.1.22]
K11182  diamine oxidase [EC:1.4.3.22]
K00128  aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K14085  aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
K00149  aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]
K01437  aspartoacylase [EC:3.5.1.15]
K00546  histamine N-methyltransferase [EC:2.1.1.8]
K00274  monoamine oxidase [EC:1.4.3.4]
K00129  aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K14755  carnosine synthase [EC:6.3.2.11]
K19787  carnosine N-methyltransferase [EC:2.1.1.22]
K22437  carnosine N-methyltransferase [EC:2.1.1.22]
K08660  cytosolic nonspecific dipeptidase [EC:3.4.13.18]
K05604  beta-Ala-His dipeptidase [EC:3.4.13.20]
K20246  L-histidine Nalpha-methyltransferase / hercynylcysteine S-oxide synthase [EC:2.1.1.44 1.21.3.10]
K18911  L-histidine Nalpha-methyltransferase [EC:2.1.1.44]
K18912  gamma-glutamyl hercynylcysteine S-oxide synthase [EC:1.14.99.50]
K07008  gamma-glutamyl hercynylcysteine S-oxide hydrolase [EC:3.5.1.118]
K20247  hercynylcysteine S-oxide lyase [EC:4.4.1.36]
K18913  hercynylcysteine S-oxide lyase [EC:4.4.1.36]
Compound
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00049  L-Aspartate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00135  L-Histidine
C00386  Carnosine
C00388  Histamine
C00439  N-Formimino-L-glutamate
C00785  Urocanate
C00860  L-Histidinol
C01044  N-Formyl-L-aspartate
C01045  N-Formyl-L-glutamate
C01100  L-Histidinol phosphate
C01152  N(pi)-Methyl-L-histidine
C01262  beta-Alanyl-N(pi)-methyl-L-histidine
C01267  3-(Imidazol-4-yl)-2-oxopropyl phosphate
C01929  L-Histidinal
C02739  1-(5-Phospho-D-ribosyl)-ATP
C02741  Phosphoribosyl-AMP
C02835  Imidazole-4-acetate
C03277  Imidazol-5-yl-pyruvate
C03409  N-Formimino-L-aspartate
C03680  4-Imidazolone-5-propanoate
C04437  1-(5-Phosphoribosyl)imidazole-4-acetate
C04666  D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04896  5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide
C04916  N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide
C05127  N-Methylhistamine
C05130  Imidazole-4-acetaldehyde
C05131  (1-Ribosylimidazole)-4-acetate
C05133  4-Imidazolone-5-acetate
C05135  4-(beta-Acetylaminoethyl)imidazole
C05565  Hydantoin-5-propionate
C05568  Imidazole lactate
C05570  Ergothioneine
C05571  Thiourocanic acid
C05572  4-Oxoglutaramate
C05575  Hercynine
C05827  Methylimidazole acetaldehyde
C05828  Methylimidazoleacetic acid
C05829  N-Carbamyl-L-glutamate
C16673  Isoglutamine
C16674  Formylisoglutamine
C20522  Dihydrourocanate
C20994  S-(Hercyn-2-yl)-L-cysteine S-oxide
C20995  gamma-L-Glutamyl-S-(hercyn-2-yl)-L-cysteine S-oxide
Related
pathway
ko00030  Pentose phosphate pathway
ko00230  Purine metabolism
ko00250  Alanine, aspartate and glutamate metabolism
LinkDB

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