KEGG   PATHWAY: mcoc04612
Entry
mcoc04612                   Pathway                                
Name
Antigen processing and presentation - Mastomys coucha (southern multimammate mouse)
Class
Organismal Systems; Immune system
Pathway map
mcoc04612  Antigen processing and presentation
mcoc04612

Other DBs
GO: 0019885 0019886 0042591
Organism
Mastomys coucha (southern multimammate mouse) [GN:mcoc]
Gene
116069447  Rfxank; DNA-binding protein RFXANK isoform X1 [KO:K08062]
116069492  Ifi30; gamma-interferon-inducible lysosomal thiol reductase [KO:K08059]
116069729  Calr; calreticulin [KO:K08057]
116073211  Hspa8; heat shock cognate 71 kDa protein [KO:K03283]
116074277  [KO:K06752]
116074291  Nfya; nuclear transcription factor Y subunit alpha isoform X1 [KO:K08064]
116074338  [KO:K06751]
116074367  Hsp90ab1; heat shock protein HSP 90-beta [KO:K04079]
116074432  Tap1; antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
116074434  [KO:K06752]
116074448  [KO:K06751]
116074449  [KO:K06751]
116074450  [KO:K06751]
116074451  [KO:K06751]
116074547  Tnf; tumor necrosis factor isoform X1 [KO:K03156]
116074620  [KO:K06751]
116074623  [KO:K06751]
116074625  [KO:K06751]
116074627  [KO:K06751]
116074637  [KO:K06751]
116074638  [KO:K06751]
116074642  [KO:K06751]
116074645  [KO:K06751]
116074664  [KO:K06751]
116074790  Hspa1l; heat shock 70 kDa protein 1-like [KO:K03283]
116074840  Tapbp; tapasin [KO:K08058]
116074843  [KO:K06752]
116074939  [KO:K06752]
116074952  [KO:K06752]
116074953  [KO:K06752]
116074954  [KO:K06752]
116075017  [KO:K06751]
116075039  [KO:K03283]
116075049  Tap2; antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
116075078  [KO:K06751]
116075117  [KO:K06752]
116075136  [KO:K06752]
116075170  [KO:K06752]
116075380  [KO:K06751]
116075381  [KO:K06751]
116076184  Nfyb; nuclear transcription factor Y subunit beta [KO:K08065]
116076208  Ifng; interferon gamma [KO:K04687]
116076804  Hspa4; heat shock 70 kDa protein 4 [KO:K09489]
116077844  Canx; calnexin [KO:K08054]
116077994  Psme3; proteasome activator complex subunit 3 isoform X1 [KO:K06698]
116080436  Hspa2; heat shock-related 70 kDa protein 2 [KO:K26598]
116080851  Lgmn; legumain [KO:K01369] [EC:3.4.22.34]
116081114  Hsp90aa1; heat shock protein HSP 90-alpha [KO:K04079]
116081960  [KO:K01365] [EC:3.4.22.15]
116082097  [KO:K01365] [EC:3.4.22.15]
116082227  [KO:K01365] [EC:3.4.22.15]
116084142  [KO:K10784]
116084368  Psme2; proteasome activator complex subunit 2 [KO:K06697]
116084801  [KO:K10784]
116084847  Psme1; proteasome activator complex subunit 1 [KO:K06696]
116085035  Ciita; MHC class II transactivator isoform X1 [KO:K08060] [EC:2.7.11.1]
116085396  Ctsb; cathepsin B isoform X1 [KO:K01363] [EC:3.4.22.1]
116087220  Cd74; HLA class II histocompatibility antigen gamma chain isoform X1 [KO:K06505]
116088513  Creb1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
116090044  Hspa5; endoplasmic reticulum chaperone BiP [KO:K09490] [EC:3.6.4.10]
116090801  Pdia3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
116090822  B2m; beta-2-microglobulin [KO:K08055]
116092874  Rfxap; regulatory factor X-associated protein [KO:K08063]
116093381  Rfx5; DNA-binding protein RFX5 isoform X1 [KO:K08061]
116093415  Ctss; cathepsin S isoform X1 [KO:K01368] [EC:3.4.22.27]
116096395  [KO:K08057]
116096553  Nfyc; nuclear transcription factor Y subunit gamma [KO:K08066]
116098178  Cd8a; T-cell surface glycoprotein CD8 alpha chain [KO:K06458]
116098356  [KO:K06516]
116099056  Cd8b; T-cell surface glycoprotein CD8 beta chain [KO:K06459]
116099586  Cd4; T-cell surface glycoprotein CD4 [KO:K06454]
116099605  Tapbpl; tapasin-related protein [KO:K28445]
116103294  Hspa6; LOW QUALITY PROTEIN: heat shock 70 kDa protein 6 [KO:K03283]
Reference
PMID:15771591
  Authors
Trombetta ES, Mellman I.
  Title
Cell biology of antigen processing in vitro and in vivo.
  Journal
Annu Rev Immunol 23:975-1028 (2005)
DOI:10.1146/annurev.immunol.22.012703.104538
Reference
PMID:15814328
  Authors
Inaba K, Inaba M.
  Title
Antigen recognition and presentation by dendritic cells.
  Journal
Int J Hematol 81:181-7 (2005)
DOI:10.1532/IJH97.04200
Reference
PMID:11905820
  Authors
Heath WR, Carbone FR.
  Title
Cross-presentation in viral immunity and self-tolerance.
  Journal
Nat Rev Immunol 1:126-34 (2001)
DOI:10.1038/35100512
Reference
PMID:15304636
  Authors
Abele R, Tampe R.
  Title
The ABCs of immunology: structure and function of TAP, the transporter associated with antigen processing.
  Journal
Physiology (Bethesda) 19:216-24 (2004)
DOI:10.1152/physiol.00002.2004
Reference
PMID:16200082
  Authors
Reith W, LeibundGut-Landmann S, Waldburger JM.
  Title
Regulation of MHC class II gene expression by the class II transactivator.
  Journal
Nat Rev Immunol 5:793-806 (2005)
DOI:10.1038/nri1708
Reference
PMID:12776207
  Authors
Honey K, Rudensky AY.
  Title
Lysosomal cysteine proteases regulate antigen presentation.
  Journal
Nat Rev Immunol 3:472-82 (2003)
DOI:10.1038/nri1110
Reference
PMID:12974477
  Authors
Sercarz EE, Maverakis E.
  Title
Mhc-guided processing: binding of large antigen fragments.
  Journal
Nat Rev Immunol 3:621-9 (2003)
DOI:10.1038/nri1149
Reference
PMID:15224093
  Authors
Ackerman AL, Cresswell P.
  Title
Cellular mechanisms governing cross-presentation of exogenous antigens.
  Journal
Nat Immunol 5:678-84 (2004)
DOI:10.1038/ni1082
Reference
PMID:16181333
  Authors
Cresswell P, Ackerman AL, Giodini A, Peaper DR, Wearsch PA.
  Title
Mechanisms of MHC class I-restricted antigen processing and cross-presentation.
  Journal
Immunol Rev 207:145-57 (2005)
DOI:10.1111/j.0105-2896.2005.00316.x
Reference
PMID:15653312
  Authors
Zika E, Ting JP.
  Title
Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes.
  Journal
Curr Opin Immunol 17:58-64 (2005)
DOI:10.1016/j.coi.2004.11.008
Reference
PMID:11244040
  Authors
Reith W, Mach B.
  Title
The bare lymphocyte syndrome and the regulation of MHC expression.
  Journal
Annu Rev Immunol 19:331-73 (2001)
DOI:10.1146/annurev.immunol.19.1.331
Reference
PMID:15745856
  Authors
Lizee G, Basha G, Jefferies WA.
  Title
Tails of wonder: endocytic-sorting motifs key for exogenous antigen presentation.
  Journal
Trends Immunol 26:141-9 (2005)
DOI:10.1016/j.it.2005.01.005
Reference
PMID:15224094
  Authors
Watts C.
  Title
The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules.
  Journal
Nat Immunol 5:685-92 (2004)
DOI:10.1038/ni1088
Reference
PMID:15653315
  Authors
Kaufmann SH, Schaible UE.
  Title
Antigen presentation and recognition in bacterial infections.
  Journal
Curr Opin Immunol 17:79-87 (2005)
DOI:10.1016/j.coi.2004.12.004
Reference
PMID:20010787
  Authors
Groettrup M, Kirk CJ, Basler M
  Title
Proteasomes in immune cells: more than peptide producers?
  Journal
Nat Rev Immunol 10:73-8 (2010)
DOI:10.1038/nri2687
Related
pathway
mcoc03050  Proteasome
mcoc04650  Natural killer cell mediated cytotoxicity
mcoc04660  T cell receptor signaling pathway
KO pathway
ko04612   

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