KEGG   PATHWAY: alim04070
Entry
alim04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Austrofundulus limnaeus (annual killifish)
Class
Environmental Information Processing; Signal transduction
Pathway map
alim04070  Phosphatidylinositol signaling system
alim04070

Organism
Austrofundulus limnaeus (annual killifish) [GN:alim]
Gene
106519864  pi4ka; phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
106532486  phosphatidylinositol 4-kinase beta-like [KO:K19801] [EC:2.7.1.67]
106529686  pi4kb; phosphatidylinositol 4-kinase beta [KO:K19801] [EC:2.7.1.67]
106531098  pi4k2a; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
106529884  pi4k2b; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
106531195  phosphatidylinositide phosphatase SAC1-A-like [KO:K21797] [EC:3.1.3.-]
106532925  phosphatidylinositide phosphatase SAC1-B-like [KO:K21797] [EC:3.1.3.-]
106535114  inpp5f; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
106533375  phosphatidylinositol 4-phosphate 5-kinase type-1 alpha-like [KO:K00889] [EC:2.7.1.68]
106533277  phosphatidylinositol 4-phosphate 5-kinase type-1 alpha-like [KO:K00889] [EC:2.7.1.68]
106526227  phosphatidylinositol 4-phosphate 5-kinase type-1 gamma-like isoform X1 [KO:K00889] [EC:2.7.1.68]
106532523  phosphatidylinositol 4-phosphate 5-kinase type-1 gamma-like [KO:K00889] [EC:2.7.1.68]
106527646  pip5k1b; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
106518114  phosphatidylinositol 4-phosphate 5-kinase type-1 alpha-like [KO:K00889] [EC:2.7.1.68]
106517523  phosphatidylinositol 4-phosphate 5-kinase type-1 beta-like [KO:K00889] [EC:2.7.1.68]
106532860  phosphatidylinositol 4-phosphate 5-kinase type-1 beta-like [KO:K00889] [EC:2.7.1.68]
106514784  ocrl; inositol polyphosphate 5-phosphatase OCRL-1 isoform X1 [KO:K01099] [EC:3.1.3.36]
106526614  inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
106510879  72 kDa inositol polyphosphate 5-phosphatase-like [KO:K20278] [EC:3.1.3.36]
106528771  inpp5e; 72 kDa inositol polyphosphate 5-phosphatase [KO:K20278] [EC:3.1.3.36]
106514139  synj1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
106529535  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like [KO:K00922] [EC:2.7.1.153]
106531899  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform-like [KO:K00922] [EC:2.7.1.153]
106522664  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
106522145  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
106530180  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
106534038  phosphatidylinositol 3-kinase regulatory subunit alpha-like [KO:K02649]
106528646  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
106519248  phosphatidylinositol 3-kinase regulatory subunit gamma-like [KO:K02649]
106530763  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
106534757  pik3r3; phosphatidylinositol 3-kinase regulatory subunit gamma [KO:K02649]
106513467  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1 [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
106528198  pten; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
106527460  inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 [KO:K03084] [EC:3.1.3.86]
106515304  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B-like isoform X1 [KO:K15909] [EC:3.1.3.86]
106517268  inppl1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 [KO:K15909] [EC:3.1.3.86]
106511218  type I inositol 3,4-bisphosphate 4-phosphatase-like [KO:K01109] [EC:3.1.3.66]
106534873  LOW QUALITY PROTEIN: 1-phosphatidylinositol 3-phosphate 5-kinase-like [KO:K00921] [EC:2.7.1.150]
106535441  1-phosphatidylinositol 3-phosphate 5-kinase-like isoform X1 [KO:K00921] [EC:2.7.1.150]
106533120  mtm1; myotubularin [KO:K01108] [EC:3.1.3.64 3.1.3.95]
106533121  myotubularin-related protein 1-like [KO:K18081] [EC:3.1.3.64 3.1.3.95]
106531999  mtmr2; myotubularin-related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
106528046  mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
106529460  mtmr3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
106517568  mtmr6; myotubularin-related protein 6 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
106528859  myotubularin-related protein 7-like [KO:K18083] [EC:3.1.3.64 3.1.3.95]
106533785  myotubularin-related protein 7-like [KO:K18083] [EC:3.1.3.64 3.1.3.95]
106519064  mtmr14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
106527630  phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like [KO:K00920] [EC:2.7.1.149]
106518074  phosphatidylinositol 5-phosphate 4-kinase type-2 gamma-like [KO:K00920] [EC:2.7.1.149]
106517543  pip4k2a; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1 [KO:K00920] [EC:2.7.1.149]
106526922  pip4k2b; phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
106515818  tmem55a; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
106520802  tmem55b; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
106523839  transmembrane protein 55B-B-like [KO:K13084] [EC:3.1.3.78]
106529974  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
106522805  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
106525737  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
106523395  pik3c2g; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
106519799  plcb2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858] [EC:3.1.4.11]
106524973  plcb3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
106529251  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1-like [KO:K05858] [EC:3.1.4.11]
106518551  plcb4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
106518553  plcb1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
106537318  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4-like [KO:K05857] [EC:3.1.4.11]
106513384  plcd1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [KO:K05857] [EC:3.1.4.11]
106530942  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-A-like [KO:K05857] [EC:3.1.4.11]
106532460  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4-like [KO:K05857] [EC:3.1.4.11]
106527597  plcd3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 [KO:K05857] [EC:3.1.4.11]
106517910  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1-like isoform X1 [KO:K05857] [EC:3.1.4.11]
106533025  plce1; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
106526007  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like [KO:K01116] [EC:3.1.4.11]
106523657  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
106536649  plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1 [KO:K05859] [EC:3.1.4.11]
106523397  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1-like [KO:K05861] [EC:3.1.4.11]
106537088  inositol polyphosphate multikinase-like [KO:K00915] [EC:2.7.1.140 2.7.1.151]
106518993  inositol polyphosphate multikinase-like [KO:K00915] [EC:2.7.1.140 2.7.1.151]
106514037  inositol-trisphosphate 3-kinase A-like [KO:K00911] [EC:2.7.1.127]
106519391  itpkc; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
106521602  itpka; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
106536770  inositol-trisphosphate 3-kinase B-like [KO:K00911] [EC:2.7.1.127]
106520010  itpkb; inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
106536095  type I inositol 1,4,5-trisphosphate 5-phosphatase-like [KO:K01106] [EC:3.1.3.56]
106521176  itpk1; inositol-tetrakisphosphate 1-kinase isoform X1 [KO:K00913] [EC:2.7.1.159 2.7.1.134]
106522330  ippk; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
106518494  inositol hexakisphosphate kinase 2-like [KO:K07756] [EC:2.7.4.21]
106518001  inositol hexakisphosphate kinase 2-like [KO:K07756] [EC:2.7.4.21]
106525049  ip6k1; inositol hexakisphosphate kinase 1 [KO:K07756] [EC:2.7.4.21]
106526640  inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2-like [KO:K13024] [EC:2.7.4.24]
106526741  ppip5k1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 [KO:K13024] [EC:2.7.4.24]
106513286  inpp1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
106515519  inositol monophosphatase 1-like [KO:K01092] [EC:3.1.3.25]
106515573  impa1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
106535662  inositol monophosphatase 1-like [KO:K01092] [EC:3.1.3.25]
106514899  impad1; inositol monophosphatase 3 [KO:K15759] [EC:3.1.3.7]
106527195  diacylglycerol kinase delta-like [KO:K00901] [EC:2.7.1.107]
106530290  dgkq; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
106510987  diacylglycerol kinase beta-like [KO:K00901] [EC:2.7.1.107]
106524437  diacylglycerol kinase iota-like [KO:K00901] [EC:2.7.1.107]
106534434  dgkd; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
106513277  dgka; diacylglycerol kinase alpha isoform X1 [KO:K00901] [EC:2.7.1.107]
106524486  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
106531263  diacylglycerol kinase eta-like isoform X1 [KO:K00901] [EC:2.7.1.107]
106522970  diacylglycerol kinase alpha-like [KO:K00901] [EC:2.7.1.107]
106524959  dgkb; LOW QUALITY PROTEIN: diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
106527982  dgkz; diacylglycerol kinase zeta [KO:K00901] [EC:2.7.1.107]
106525436  phosphatidate cytidylyltransferase 2-like [KO:K00981] [EC:2.7.7.41]
106535345  phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
106510850  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
106518058  inositol 1,4,5-trisphosphate receptor type 1-like [KO:K04958]
106527163  inositol 1,4,5-trisphosphate receptor type 1-like [KO:K04958]
106515612  itpr2; inositol 1,4,5-trisphosphate receptor type 2 isoform X1 [KO:K04959]
106527884  LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 3-like [KO:K04960]
106518739  protein kinase C alpha type [KO:K02677] [EC:2.7.11.13]
106534248  prkcb; protein kinase C beta type isoform X1 [KO:K02677] [EC:2.7.11.13]
106519663  protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
106516520  protein kinase C beta type-like [KO:K19662] [EC:2.7.11.13]
106520517  protein kinase C alpha type-like [KO:K19663] [EC:2.7.11.13]
106527471  calmodulin [KO:K02183]
106526330  calmodulin [KO:K02183]
106515407  calm3; calmodulin [KO:K02183]
106526525  calmodulin-like [KO:K02183]
106512977  calml4; calmodulin-like protein 4 [KO:K02183]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
alim04020  Calcium signaling pathway
alim04144  Endocytosis
alim04510  Focal adhesion
KO pathway
ko04070   
LinkDB

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