KEGG   PATHWAY: cpic04070
Entry
cpic04070                   Pathway                                
Name
Phosphatidylinositol signaling system - Chrysemys picta (western painted turtle)
Class
Environmental Information Processing; Signal transduction
Pathway map
cpic04070  Phosphatidylinositol signaling system
cpic04070

Organism
Chrysemys picta (western painted turtle) [GN:cpic]
Gene
101932464  PI4KA; LOW QUALITY PROTEIN: phosphatidylinositol 4-kinase alpha [KO:K00888] [EC:2.7.1.67]
101940461  PI4KB; LOW QUALITY PROTEIN: phosphatidylinositol 4-kinase beta [KO:K19801] [EC:2.7.1.67]
101948984  PI4K2B; phosphatidylinositol 4-kinase type 2-beta isoform X1 [KO:K13711] [EC:2.7.1.67]
101942533  PI4K2A; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
101935477  SACM1L; phosphatidylinositol-3-phosphatase SAC1 [KO:K21797] [EC:3.1.3.-]
101932015  INPP5F; phosphatidylinositide phosphatase SAC2 isoform X2 [KO:K21798] [EC:3.1.3.-]
101933832  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X9 [KO:K00889] [EC:2.7.1.68]
101941302  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
101941479  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X5 [KO:K00889] [EC:2.7.1.68]
101936637  INPP5B; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X3 [KO:K01099] [EC:3.1.3.36]
101937608  OCRL; inositol polyphosphate 5-phosphatase OCRL isoform X2 [KO:K01099] [EC:3.1.3.36]
101940841  INPP5E; phosphatidylinositol polyphosphate 5-phosphatase type IV isoform X1 [KO:K20278] [EC:3.1.3.36]
101945887  SYNJ1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
101946228  SYNJ2; synaptojanin-2 [KO:K20279] [EC:3.1.3.36]
101935421  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
101934126  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
101940315  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
101953817  PIK3R1; phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [KO:K02649]
101945673  PIK3R2; phosphatidylinositol 3-kinase regulatory subunit beta isoform X1 [KO:K02649]
101947423  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1 [KO:K02649]
101934509  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
101950741  INPP5D; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1 [KO:K03084] [EC:3.1.3.86]
101951468  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2-like isoform X2 [KO:K15909] [EC:3.1.3.86]
101932232  INPPL1; LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 [KO:K15909] [EC:3.1.3.86]
101948633  INPP4B; inositol polyphosphate 4-phosphatase type II isoform X1 [KO:K01109] [EC:3.1.3.66]
101948721  INPP4A; inositol polyphosphate-4-phosphatase type I A isoform X14 [KO:K01109] [EC:3.1.3.66]
101941143  PIKFYVE; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
101944474  MTM1; myotubularin [KO:K01108] [EC:3.1.3.64 3.1.3.95]
101930881  MTMR2; myotubularin-related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
101931312  MTMR1; myotubularin-related protein 1 isoform X2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
101951257  MTMR4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
101939749  MTMR3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
101932567  MTMR6; myotubularin-related protein 6 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
101949926  MTMR8; myotubularin-related protein 8 isoform X2 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
101948247  MTMR7; myotubularin-related protein 7 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
101940028  MTMR14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
101948701  PIP4K2B; phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
101938310  PIP4K2A; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X2 [KO:K00920] [EC:2.7.1.149]
101946409  PIP4K2C; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1 [KO:K00920] [EC:2.7.1.149]
101946066  PIP4P1; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [KO:K13084] [EC:3.1.3.78]
101937348  PIP4P2; type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [KO:K13084] [EC:3.1.3.78]
101944037  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X2 [KO:K00914] [EC:2.7.1.137]
101944776  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [KO:K00923] [EC:2.7.1.154]
101951383  PIK3C2A; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1 [KO:K00923] [EC:2.7.1.154]
101931624  PIK3C2G; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma [KO:K00923] [EC:2.7.1.154]
101930785  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
101940400  PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X1 [KO:K05858] [EC:3.1.4.11]
101931546  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X2 [KO:K05858] [EC:3.1.4.11]
101932753  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
101941573  PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [KO:K05857] [EC:3.1.4.11]
101944484  PLCD4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
101933267  PLCD3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X2 [KO:K05857] [EC:3.1.4.11]
101944378  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
101935550  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2 [KO:K01116] [EC:3.1.4.11]
101930905  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like [KO:K01116] [EC:3.1.4.11]
101932685  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
101931350  PLCZ1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [KO:K05861] [EC:3.1.4.11]
101949940  IPMK; inositol polyphosphate multikinase isoform X2 [KO:K00915] [EC:2.7.1.140 2.7.1.151]
101948746  ITPKB; inositol-trisphosphate 3-kinase B isoform X1 [KO:K00911] [EC:2.7.1.127]
101942324  inositol-trisphosphate 3-kinase B-like isoform X1 [KO:K00911] [EC:2.7.1.127]
101951742  ITPKA; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
101940311  INPP5A; inositol polyphosphate-5-phosphatase A isoform X1 [KO:K01106] [EC:3.1.3.56]
101949054  inositol-tetrakisphosphate 1-kinase-like [KO:K00913] [EC:2.7.1.159 2.7.1.134]
101948262  ITPK1; inositol-tetrakisphosphate 1-kinase isoform X1 [KO:K00913] [EC:2.7.1.159 2.7.1.134]
101954054  IPPK; inositol-pentakisphosphate 2-kinase isoform X1 [KO:K10572] [EC:2.7.1.158]
101936418  IP6K3; inositol hexakisphosphate kinase 3 isoform X1 [KO:K07756] [EC:2.7.4.21]
101932494  IP6K2; inositol hexakisphosphate kinase 2 isoform X1 [KO:K07756] [EC:2.7.4.21]
101932911  IP6K1; inositol hexakisphosphate kinase 1 isoform X1 [KO:K07756] [EC:2.7.4.21]
101952432  PPIP5K1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform X1 [KO:K13024] [EC:2.7.4.24]
101946048  PPIP5K2; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X2 [KO:K13024] [EC:2.7.4.24]
101953281  INPP1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
101935384  IMPA1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
101932283  IMPA2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
101946952  BPNT2; Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase [KO:K15759] [EC:3.1.3.7]
101940928  DGKI; diacylglycerol kinase iota isoform X3 [KO:K00901] [EC:2.7.1.107]
101940221  diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
101933664  DGKA; diacylglycerol kinase alpha [KO:K00901] [EC:2.7.1.107]
101936224  DGKG; diacylglycerol kinase gamma isoform X1 [KO:K00901] [EC:2.7.1.107]
101950066  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
101946155  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
101943810  DGKH; diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
101939308  DGKB; diacylglycerol kinase beta isoform X2 [KO:K00901] [EC:2.7.1.107]
101950294  diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
101932990  DGKZ; diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
101932654  DGKD; diacylglycerol kinase delta isoform X1 [KO:K00901] [EC:2.7.1.107]
101934849  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
101951593  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
101938540  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform X1 [KO:K00999] [EC:2.7.8.11]
101945436  ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X3 [KO:K04958]
101931123  ITPR2; LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 2 [KO:K04959]
101935702  ITPR3; LOW QUALITY PROTEIN: inositol 1,4,5-trisphosphate receptor type 3 [KO:K04960]
101949360  PRKCA; protein kinase C alpha type isoform X1 [KO:K02677] [EC:2.7.11.13]
101951581  PRKCB; protein kinase C beta type isoform X1 [KO:K19662] [EC:2.7.11.13]
101937053  PRKCG; LOW QUALITY PROTEIN: protein kinase C gamma type [KO:K19663] [EC:2.7.11.13]
101951852  CALM2; calmodulin-2 [KO:K02183]
101937671  calmodulin-1 [KO:K02183]
101942525  calmodulin isoform X1 [KO:K02183]
101952671  CALML6; calmodulin-like protein 6 isoform X1 [KO:K02183]
101947874  CALML4; calmodulin-like protein 4 isoform X1 [KO:K02183]
101938950  CALM3; calmodulin-3 [KO:K02183]
101936416  CALM1; calmodulin-1 [KO:K02183]
Compound
C00076  Calcium cation
C00137  myo-Inositol
C00269  CDP-diacylglycerol
C00416  Phosphatidate
C00641  1,2-Diacyl-sn-glycerol
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C11174  1-Diphosinositol pentakisphosphate
C11526  5-PP-InsP5
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C20690  1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate
Reference
PMID:19580826
  Authors
Sasaki T, Takasuga S, Sasaki J, Kofuji S, Eguchi S, Yamazaki M, Suzuki A
  Title
Mammalian phosphoinositide kinases and phosphatases.
  Journal
Prog Lipid Res 48:307-43 (2009)
DOI:10.1016/j.plipres.2009.06.001
Reference
PMID:19439500
  Authors
Shears SB
  Title
Diphosphoinositol polyphosphates: metabolic messengers?
  Journal
Mol Pharmacol 76:236-52 (2009)
DOI:10.1124/mol.109.055897
Related
pathway
cpic04020  Calcium signaling pathway
cpic04144  Endocytosis
cpic04510  Focal adhesion
KO pathway
ko04070   
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