Entry Name Malaria - Macaca fascicularis (crab-eating macaque)
Description Plasmodium protozoa are parasites that account for malaria infection. Sporozoite forms of the parasite are injected by mosquito bites under the skin and are carried to the liver where they develop into the merozoite form.
Class Human Diseases; Infectious disease: parasiticBRITE hierarchy
Pathway map Ortholog table Organism Macaca fascicularis (crab-eating macaque) [GN:
mcf ]
Gene 102119582 LRP1; prolow-density lipoprotein receptor-related protein 1 [KO:K04550 ]
101866832 MYD88; myeloid differentiation primary response protein MyD88 isoform X1 [KO:K04729 ]
102129546 TGFB1; transforming growth factor beta-1 proprotein isoform X2 [KO:K13375 ]
101925182 TGFB2; transforming growth factor beta-2 proprotein isoform X1 [KO:K13376 ]
102123087 CSF3; granulocyte colony-stimulating factor isoform X3 [KO:K05423 ]
102139342 KLRB1; killer cell lectin-like receptor subfamily B member 1 isoform X1 [KO:K06543 ]
102116805 CR1L; complement component receptor 1-like protein isoform X1 [KO:K04011 ]
102117792 PECAM1; platelet endothelial cell adhesion molecule isoform X1 [KO:K06471 ]
102118696 CD40; tumor necrosis factor receptor superfamily member 5 isoform X1 [KO:K03160 ]
Compound Reference Authors Morahan BJ, Wang L, Coppel RL
Title No TRAP, no invasion.
Journal Reference Authors Shakibaei M, Frevert U
Title Dual interaction of the malaria circumsporozoite protein with the low density lipoprotein receptor-related protein (LRP) and heparan sulfate proteoglycans.
Journal Reference Authors Silvie O, Franetich JF, Renia L, Mazier D
Title Malaria sporozoite: migrating for a living.
Journal Reference Authors Mota MM, Giordano S, Rodriguez A
Title Targeting Plasmodium host cells: survival within hepatocytes.
Journal Reference Authors Cowman AF, Crabb BS
Title The Plasmodium falciparum genome--a blueprint for erythrocyte invasion.
Journal Reference Authors O'Donnell RA, Blackman MJ
Title The role of malaria merozoite proteases in red blood cell invasion.
Journal Reference Authors Iyer J, Gruner AC, Renia L, Snounou G, Preiser PR
Title Invasion of host cells by malaria parasites: a tale of two protein families.
Journal Reference Authors Chitnis CE
Title Molecular insights into receptors used by malaria parasites for erythrocyte invasion.
Journal Reference Authors Rasti N, Wahlgren M, Chen Q
Title Molecular aspects of malaria pathogenesis.
Journal Reference Authors Clark IA, Rockett KA, Cowden WB
Title Proposed link between cytokines, nitric oxide and human cerebral malaria.
Journal Reference Authors Hisaeda H, Tetsutani K, Imai T, Moriya C, Tu L, Hamano S, Duan X, Chou B, Ishida H, Aramaki A, Shen J, Ishii KJ, Coban C, Akira S, Takeda K, Yasutomo K, Torii M, Himeno K
Title Malaria parasites require TLR9 signaling for immune evasion by activating regulatory T cells.
Journal Reference Authors Chen Q, Schlichtherle M, Wahlgren M
Title Molecular aspects of severe malaria.
Journal Reference Authors Miller LH, Baruch DI, Marsh K, Doumbo OK
Title The pathogenic basis of malaria.
Journal Reference Authors Faille D, El-Assaad F, Alessi MC, Fusai T, Combes V, Grau GE
Title Platelet-endothelial cell interactions in cerebral malaria: the end of a cordial understanding.
Journal Reference Authors Schofield L, Grau GE
Title Immunological processes in malaria pathogenesis.
Journal Reference Authors Ishino T, Yano K, Chinzei Y, Yuda M
Title Cell-passage activity is required for the malarial parasite to cross the liver sinusoidal cell layer.
Journal Reference Authors Kariu T, Ishino T, Yano K, Chinzei Y, Yuda M
Title CelTOS, a novel malarial protein that mediates transmission to mosquito and vertebrate hosts.
Journal Reference Authors Cox D, McConkey S
Title The role of platelets in the pathogenesis of cerebral malaria.
Journal Related mcf04610 Complement and coagulation cascades
mcf04620 Toll-like receptor signaling pathway
KO pathway LinkDB All DBs
