KEGG   ORTHOLOGY: K05443
Entry
K05443                      KO                                     
Symbol
IL10, CSIF
Name
interleukin 10
Pathway
map04060  Cytokine-cytokine receptor interaction
map04061  Viral protein interaction with cytokine and cytokine receptor
map04068  FoxO signaling pathway
map04148  Efferocytosis
map04625  C-type lectin receptor signaling pathway
map04630  JAK-STAT signaling pathway
map04660  T cell receptor signaling pathway
map04672  Intestinal immune network for IgA production
map05133  Pertussis
map05135  Yersinia infection
map05140  Leishmaniasis
map05142  Chagas disease
map05143  African trypanosomiasis
map05144  Malaria
map05145  Toxoplasmosis
map05146  Amoebiasis
map05150  Staphylococcus aureus infection
map05152  Tuberculosis
map05310  Asthma
map05320  Autoimmune thyroid disease
map05321  Inflammatory bowel disease
map05322  Systemic lupus erythematosus
map05330  Allograft rejection
Disease
H00083  Allograft rejection
H00084  Graft-versus-host disease
H00630  Rheumatoid arthritis
H01227  Inflammatory bowel disease (IBD)
H01466  Ulcerative colitis
H01563  HIV infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05443  IL10, CSIF; interleukin 10
   04068 FoxO signaling pathway
    K05443  IL10, CSIF; interleukin 10
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05443  IL10, CSIF; interleukin 10
   04061 Viral protein interaction with cytokine and cytokine receptor
    K05443  IL10, CSIF; interleukin 10
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    K05443  IL10, CSIF; interleukin 10
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    K05443  IL10, CSIF; interleukin 10
   04660 T cell receptor signaling pathway
    K05443  IL10, CSIF; interleukin 10
   04672 Intestinal immune network for IgA production
    K05443  IL10, CSIF; interleukin 10
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    K05443  IL10, CSIF; interleukin 10
   05133 Pertussis
    K05443  IL10, CSIF; interleukin 10
   05150 Staphylococcus aureus infection
    K05443  IL10, CSIF; interleukin 10
   05152 Tuberculosis
    K05443  IL10, CSIF; interleukin 10
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K05443  IL10, CSIF; interleukin 10
   05144 Malaria
    K05443  IL10, CSIF; interleukin 10
   05145 Toxoplasmosis
    K05443  IL10, CSIF; interleukin 10
   05140 Leishmaniasis
    K05443  IL10, CSIF; interleukin 10
   05142 Chagas disease
    K05443  IL10, CSIF; interleukin 10
   05143 African trypanosomiasis
    K05443  IL10, CSIF; interleukin 10
  09163 Immune disease
   05310 Asthma
    K05443  IL10, CSIF; interleukin 10
   05322 Systemic lupus erythematosus
    K05443  IL10, CSIF; interleukin 10
   05320 Autoimmune thyroid disease
    K05443  IL10, CSIF; interleukin 10
   05321 Inflammatory bowel disease
    K05443  IL10, CSIF; interleukin 10
   05330 Allograft rejection
    K05443  IL10, CSIF; interleukin 10
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K05443  IL10, CSIF; interleukin 10
   00536 Glycosaminoglycan binding proteins
    K05443  IL10, CSIF; interleukin 10
Cytokines and neuropeptides [BR:ko04052]
 Cytokines
  Interleukins
   K05443  IL10, CSIF; interleukin 10
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Cytokines
   K05443  IL10, CSIF; interleukin 10
Other DBs
GO: 0005141
Genes
HSA: 3586(IL10)
PTR: 469657(IL10)
PPS: 100990760(IL10)
GGO: 101130439(IL10)
PON: 100446386(IL10)
PPYG: 129032072(IL10)
NLE: 100580426(IL10)
HMH: 116457671(IL10)
SSYN: 129458182(IL10)
MCC: 694931(IL10)
MCF: 102133450(IL10)
MTHB: 126949419
MNI: 105484849(IL10)
CSAB: 103230190(IL10)
CATY: 105576723(IL10)
PANU: 101024270(IL10)
TGE: 112636140(IL10)
MLEU: 105554609(IL10)
RRO: 104661740(IL10)
RBB: 108535116(IL10)
TFN: 117076749(IL10)
PTEH: 111522811(IL10)
CANG: 105508594(IL10)
CJC: 100386149(IL10)
SBQ: 101052580(IL10)
CIMI: 108302085(IL10)
ANAN: 105722001(IL10)
CSYR: 103257993(IL10)
MMUR: 105869019(IL10)
LCAT: 123627137(IL10)
PCOQ: 105805858(IL10)
OGA: 100966466(IL10)
MMU: 16153(Il10)
MCAL: 110304323(Il10)
MPAH: 110322547(Il10)
RNO: 25325(Il10)
MCOC: 116070135(Il10)
ANU: 117716509(Il10)
MUN: 110550319(Il10)
CGE: 100759320(Il10)
MAUA: 101840942(Il10)
PROB: 127236357(Il10)
PLEU: 114698039(Il10)
MORG: 121446440(Il10)
MFOT: 126505054
AAMP: 119827837(Il10)
NGI: 103725974(Il10)
HGL: 101708273(Il10)
CPOC: 100715618(Il10)
CCAN: 109688365(Il10)
DORD: 105986462(Il10)
DSP: 122109459(Il10)
PLOP: 125359290(Il10)
NCAR: 124961999
MMMA: 107140606(Il10)
OCU: 100008701(IL10)
OPI: 101529586(IL10)
TUP: 102484682(IL10)
GVR: 103600438(IL10)
CFA: 403628(IL10)
CLUD: 112648300(IL10)
VVP: 112910982(IL10)
VLG: 121495475(IL10)
NPO: 129505964(IL10)
AML: 100481671(IL10)
UMR: 103657674(IL10)
UAH: 113242596(IL10)
UAR: 123785865(IL10)
ELK: 111151100
LLV: 125086446
MPUF: 101672145(IL10)
MNP: 132026140(IL10)
MLK: 131815004(IL10)
NVS: 122918166(IL10)
ORO: 101379900(IL10)
EJU: 114221910(IL10)
ZCA: 113933458(IL10)
MLX: 118014251(IL10)
NSU: 110573884(IL10)
LWW: 102744308(IL10)
FCA: 493683(IL10)
PYU: 121022407(IL10)
PCOO: 112857775(IL10)
PBG: 122475789(IL10)
PVIV: 125155666(IL10)
LRUF: 124510058
PTG: 102957558(IL10)
PPAD: 109255562(IL10)
PUC: 125916760 125916763
AJU: 106981772
HHV: 120245581(IL10)
BTA: 281246(IL10)
BOM: 102270457(IL10)
BIU: 109570808(IL10)
BBUB: 102400790(IL10)
BBIS: 104998829(IL10)
CHX: 100860746(IL10)
OAS: 443342(IL10)
BTAX: 128061792(IL10)
ODA: 120879937(IL10)
MBEZ: 129551731(IL10)
SSC: 397106(IL10)
CFR: 102518112(IL10)
CBAI: 105075425(IL10)
CDK: 105098609(IL10)
VPC: 102537608(IL10)
BACU: 102998666(IL10)
BMUS: 118900644(IL10)
LVE: 103083023(IL10)
OOR: 101271889(IL10)
DLE: 111184748(IL10)
PCAD: 102973585(IL10)
PSIU: 116757459(IL10)
NASI: 112403503(IL10)
ECB: 100034187(IL10)
EPZ: 103541620(IL10)
EAI: 106823331(IL10)
MYB: 102245406(IL10)
MYD: 102774814(IL10)
MMYO: 118673654(IL10)
MLF: 102431174(IL10)
MDT: 132220480(IL10)
PKL: 118721544(IL10)
EFUS: 103297476(IL10)
MNA: 107539442(IL10)
DRO: 112315005(IL10)
SHON: 119001704(IL10)
AJM: 119056783(IL10)
PDIC: 114511966(IL10)
PHAS: 123820638(IL10)
MMF: 118637558(IL10)
PPAM: 129062079(IL10)
HAI: 109374504(IL10)
RFQ: 117014904(IL10)
PALE: 102887289(IL10)
PGIG: 120618001(IL10)
PVP: 105308926(IL10)
RAY: 107502233(IL10)
MJV: 108403017(IL10)
TOD: 119233943(IL10)
SARA: 101541610(IL10)
SETR: 126004565(IL10)
LAV: 100665398(IL10)
TMU: 101342743
ETF: 101650414(IL10)
DNM: 101417379(IL10)
MDO: 100616748(IL10)
GAS: 123245974(IL10)
SHR: 100917955(IL10)
AFZ: 127561582
PCW: 110219537(IL10)
TVP: 118848292(IL10)
OAA: 100077352(IL10)
GGA: 428264(IL10)
PCOC: 116237044(IL10)
MGP: 100303698(IL10)
CJO: 107324788(IL10)
TPAI: 128088080(IL10)
LMUT: 125684188(IL10)
NMEL: 110388242(IL10)
APLA: 101801826(IL10)
ACYG: 106041265(IL10)
CATA: 118255369(IL10)
AFUL: 116498884(IL10)
TGU: 100218293(IL10)
LSR: 110473089(IL10)
SCAN: 103822394(IL10)
PMOA: 120497635(IL10)
OTC: 121345625(IL10)
PRUF: 121349783(IL10)
GFR: 102044259(IL10)
FAB: 101814435(IL10)
OMA: 130263571(IL10)
PHI: 102105573(IL10)
PMAJ: 107199487(IL10)
CCAE: 111939675(IL10)
CCW: 104692511(IL10)
CBRC: 103620368(IL10)
ETL: 114063133(IL10)
ZAB: 102074567(IL10)
ZLE: 135457967(IL10)
ACHL: 103804662(IL10)
SVG: 106850905(IL10)
MMEA: 130586769 130587040
HRT: 120762975(IL10)
SATI: 136371461(IL10)
FPG: 101911023(IL10)
FCH: 102051109(IL10)
CCRI: 104163255(IL10)
NNT: 104412614(IL10)
SHAB: 115602318(IL10)
ACUN: 113488871(IL10)
TALA: 104369339(IL10)
ACHC: 115335475(IL10)
HALD: 104320115(IL10)
HLE: 104839037(IL10)
AGEN: 126052461
GCL: 127026313
CSTI: 104558383(IL10)
LDI: 104352272(IL10)
MNB: 103770571(IL10)
DPUB: 104297263(IL10)
AVIT: 104275301(IL10)
BRHI: 104496730(IL10)
EGZ: 104134372(IL10)
NNI: 104013114(IL10)
PCRI: 104030939(IL10)
PADL: 103919782(IL10)
AFOR: 103893586(IL10)
FGA: 104080473(IL10)
GSTE: 104253454(IL10)
CLV: 102086424(IL10)
MUI: 104544127(IL10)
PGUU: 104472498(IL10)
PLET: 104621032(IL10)
EHS: 104516148(IL10)
CMAC: 104477037(IL10)
CUCA: 104061860(IL10)
TEO: 104384067(IL10)
BREG: 104638569(IL10)
OHA: 104336179(IL10)
ACAR: 104523982(IL10)
CPEA: 104388630(IL10)
CVF: 104289282(IL10)
RTD: 128900463(IL10)
AAM: 106495801(IL10)
AROW: 112971668(IL10)
NPD: 112944654(IL10)
TGT: 104573139(IL10)
DNE: 112990134(IL10)
SCAM: 104142328(IL10)
ASN: 102383212(IL10)
AMJ: 102569168(IL10)
CPOO: 109317713(IL10)
GGN: 109295421(IL10)
PSS: 102453719 102453958
CMY: 102943573(IL10)
CCAY: 125625191(IL10)
DCC: 119846430(IL10)
CPIC: 101942064(IL10)
TST: 117877036(IL10)
CABI: 116832096(IL10)
MRV: 120404516(IL10)
ACS: 100563091(il10)
ASAO: 132772637(IL10)
PVT: 110088413(IL10)
SUND: 121927618(IL10)
PBI: 103050412(IL10)
PMUR: 107297703(IL10)
CTIG: 120297448(IL10)
TSR: 106541017(IL10)
PGUT: 117664383(IL10)
PTEX: 113446135(IL10)
NSS: 113418155(IL10)
VKO: 123034247(IL10)
PMUA: 114599330(IL10)
PRAF: 128416137(IL10)
ZVI: 118088579(IL10)
HCG: 128324336(IL10)
GJA: 107124328(IL10)
EMC: 129330396(IL10)
XLA: 108707703(il10.L) 108709106(il10.S)
XTR: 100335053(il10)
NPR: 108793183(IL10)
RTEM: 120928638(IL10)
BBUF: 120993313(IL10)
BGAR: 122932426(IL10)
MUO: 115482056(IL10)
GSH: 117347547(IL10)
DRE: 553957(il10)
SRX: 107728608 107739303
SANH: 107656017 107675843
SGH: 107555708 107590185
CCAR: 109076801 109092304
CAUA: 113055241 113111236
CGIB: 127968460 128022388
PTET: 122354224(il10)
LROH: 127173204(il10)
OMC: 131549391(il10)
PPRM: 120480520(il10)
MAMB: 125256445(il10) 125256447
CIDE: 127522978
CERY: 137021108(il10)
MASI: 127426161 127428290
TROS: 130571262(il10)
TDW: 130410311(il10)
MANU: 129427712 129427844 129428222
IPU: 108255115
IFU: 128624804(il10)
PHYP: 113539679(il10)
SMEO: 124402591(il10)
TFD: 113641573(il10)
TVC: 132838320(il10)
TRN: 134301619(il10)
AMEX: 103032747(il10)
CMAO: 118799562(il10) 118800021
EEE: 113579162(il10)
CHAR: 105904132(il10)
TRU: 101074817(il10)
TFS: 130524276(il10)
LCO: 104925242(il10)
NCC: 104959967(il10)
TBEN: 117486460(il10)
CGOB: 115007961(il10)
PGEO: 117446978(il10)
GACU: 117547534(il10)
EMAC: 134882177(il10)
ELY: 117256396(il10)
EFO: 125891411(il10)
PLEP: 121950263(il10)
SLUC: 116066893(il10)
ECRA: 117943572(il10)
ESP: 116685303
PFLV: 114554280(il10)
GAT: 120835201(il10)
PPUG: 119194249(il10)
AFB: 129105680(il10)
CLUM: 117730862(il10)
PSWI: 130208544(il10)
MSAM: 119885912(il10)
SCHU: 122867749(il10)
CUD: 121528730(il10)
ALAT: 119021277(il10) 119021944
MZE: 101471154(il10)
ONL: 100694754(il10)
OAU: 116326454(il10)
OLA: 101167784(il10)
OML: 112145307(il10)
CSAI: 133449471(il10)
XMA: 102227955(il10)
XCO: 114134980(il10)
XHE: 116710694(il10)
PRET: 103464871(il10)
PFOR: 103144318(il10)
PLAI: 106958315(il10)
PMEI: 106933920(il10)
GAF: 122833800(il10)
PPRL: 129358167(il10)
CVG: 107083320(il10)
CTUL: 119791814(il10)
GMU: 124856209(il10)
NFU: 107385951(il10)
KMR: 108235691(il10)
ALIM: 106513303(il10)
NWH: 119411969(il10)
AOCE: 111566563(il10)
MCEP: 125007105(il10)
CSEM: 103386072(il10)
POV: 109629080(il10)
SSEN: 122767793(il10)
HHIP: 117762109(il10)
HSP: 118104973(il10)
PPLT: 128455524(il10)
SMAU: 118309911(il10)
LCF: 108890002
SDU: 111221640(il10)
SLAL: 111667880(il10)
XGL: 120806972(il10)
HCQ: 109522542(il10)
SSCV: 125977026
SBIA: 133507461(il10)
PEE: 133408596(il10)
PTAO: 133483970(il10)
BPEC: 110171287
MALB: 109956256
BSPL: 114856085(il10)
SJO: 128355544(il10)
SASA: 100136512(il-10) 106566262 106594794(IL-10)
STRU: 115149936 115207229
OTW: 112236527 121846822(il10)
OMY: 100136835(il10) 100653479(il10b)
OGO: 124004224 124018395(il10)
ONE: 115122049(il10)
OKI: 109867085 109885829
OKE: 118381909(il10) 127922752
SALP: 112073524
SNH: 120037215 120064680(il10)
CCLU: 121575974 121578587 121578588
ELS: 105013217(il10)
SFM: 108938191(il10)
PKI: 111854443(il10)
AANG: 118207923 118211122(il10)
LOC: 102692739(il10)
PSPA: 121300208 121304658(il10)
ARUT: 117429786 117435027
PSEX: 120526901(il10)
LCM: 102366797(IL10)
CMK: 103182496(il10)
RTP: 109918245(il10)
CPLA: 122562970(il10)
LERI: 129708969
TDC: 119346659
 » show all
Reference
PMID:2161559
  Authors
Moore KW, Vieira P, Fiorentino DF, Trounstine ML, Khan TA, Mosmann TR
  Title
Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI.
  Journal
Science 248:1230-4 (1990)
DOI:10.1126/science.2161559
  Sequence
[mmu:16153]
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