KEGG   PATHWAY: pmaj03083
Entry
pmaj03083                   Pathway                                
Name
Polycomb repressive complex - Parus major (Great Tit)
Class
Genetic Information Processing; Chromosome
Pathway map
pmaj03083  Polycomb repressive complex
pmaj03083

Organism
Parus major (Great Tit) [GN:pmaj]
Gene
107215126  EZH1; histone-lysine N-methyltransferase EZH1 [KO:K17451] [EC:2.1.1.356]
107200653  EZH2; histone-lysine N-methyltransferase EZH2 isoform X1 [KO:K11430] [EC:2.1.1.356]
107207057  EED; polycomb protein EED [KO:K11462]
107212472  SUZ12; polycomb protein SUZ12 [KO:K11463]
107214082  RBBP4; histone-binding protein RBBP4 [KO:K10752]
107207806  RBBP7; LOW QUALITY PROTEIN: histone-binding protein RBBP7 [KO:K11659]
107208243  MTF2; metal-response element-binding transcription factor 2 isoform X1 [KO:K11485]
107212200  PHF19; PHD finger protein 19 [KO:K11486]
107199020  SKI/DACH domain-containing protein 1 [KO:K26259]
107206782  uncharacterized protein LOC107206782 [KO:K26260]
107206783  LCOR; ligand-dependent corepressor [KO:K26260]
107204908  AEBP2; zinc finger protein AEBP2 isoform X3 [KO:K17452]
107199858  JARID2; protein Jumonji [KO:K11478]
107210501  BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 isoform X1 [KO:K08588] [EC:3.4.19.12]
107213391  ASXL1; polycomb group protein ASXL1 isoform X1 [KO:K11471]
107198689  ASXL2; putative Polycomb group protein ASXL2 [KO:K11471]
107200296  ASXL3; putative Polycomb group protein ASXL3 isoform X1 [KO:K11471]
107203795  OGT; UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1 [KO:K09667] [EC:2.4.1.255]
107205949  YY1; LOW QUALITY PROTEIN: transcriptional repressor protein YY1 [KO:K09201]
107207502  MBD5; methyl-CpG-binding domain protein 5 [KO:K23219]
107211306  FOXK1; forkhead box protein K1 [KO:K09404]
107212388  FOXK2; forkhead box protein K2 isoform X1 [KO:K09404]
107208090  RNF2; E3 ubiquitin-protein ligase RING2 [KO:K10695] [EC:2.3.2.27]
107198302  polycomb complex protein BMI-1 [KO:K11459]
107212433  CBX2; chromobox protein homolog 2 [KO:K11451]
107212257  CBX4; E3 SUMO-protein ligase CBX4 [KO:K11452] [EC:2.3.2.-]
107204185  CBX6; chromobox protein homolog 6 [KO:K11453]
107204953  CBX7; chromobox protein homolog 7 isoform X1 [KO:K11454]
107212249  CBX8; chromobox protein homolog 8 isoform X1 [KO:K11455]
107200691  PHC1; polyhomeotic-like protein 1 isoform X2 [KO:K11456]
107213546  PHC2; polyhomeotic-like protein 2 [KO:K11457]
107208900  PHC3; polyhomeotic-like protein 3 isoform X1 [KO:K11458]
107207119  SCML2; sex comb on midleg-like protein 2 isoform X1 [KO:K11465]
107214171  SCMH1; polycomb protein SCMH1 isoform X1 [KO:K11461]
107205065  SFMBT2; scm-like with four MBT domains protein 2 [KO:K26269]
107210354  SFMBT1; scm-like with four MBT domains protein 1 [KO:K26269]
107210721  UBE2D2; ubiquitin-conjugating enzyme E2 D2 isoform X7 [KO:K06689] [EC:2.3.2.23]
107202928  UBE2D3; ubiquitin-conjugating enzyme E2 D3 isoform X1 [KO:K06689] [EC:2.3.2.23]
107215914  UBE2D1; ubiquitin-conjugating enzyme E2 D1 isoform X1 [KO:K06689] [EC:2.3.2.23]
107209593  USP16; ubiquitin carboxyl-terminal hydrolase 16 isoform X1 [KO:K11844] [EC:3.4.19.12]
107201421  USP45; ubiquitin carboxyl-terminal hydrolase 45 isoform X1 [KO:K11844] [EC:3.4.19.12]
107210487  RYBP; RING1 and YY1-binding protein isoform X1 [KO:K11469]
107204825  YAF2; YY1-associated factor 2 [KO:K11468]
107202785  PCGF1; polycomb group RING finger protein 1 [KO:K11487]
107206215  KDM2A; lysine-specific demethylase 2A [KO:K10276] [EC:1.14.11.27]
107211564  KDM2B; lysine-specific demethylase 2B isoform X1 [KO:K10276] [EC:1.14.11.27]
107206595  BCOR; BCL-6 corepressor isoform X1 [KO:K23215]
107204007  BCORL1; BCL-6 corepressor-like protein 1 isoform X1 [KO:K26199]
107210641  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
107211224  USP7; ubiquitin carboxyl-terminal hydrolase 7 isoform X1 [KO:K11838] [EC:3.4.19.12]
107198169  PCGF3; polycomb group RING finger protein 3 isoform X1 [KO:K11488]
107206840  PCGF5; polycomb group RING finger protein 5 isoform X1 [KO:K11489]
107212675  AUTS2; autism susceptibility gene 2 protein [KO:K23214]
107211775  FBRSL1; fibrosin-1-like protein isoform X1 [KO:K26254]
107215304  DCAF7; DDB1- and CUL4-associated factor 7 [KO:K11805]
107199691  TEX10; testis-expressed protein 10 isoform X1 [KO:K14827]
107204429  EP300; histone acetyltransferase p300 isoform X1 [KO:K04498] [EC:2.3.1.48]
107211174  CREBBP; CREB-binding protein isoform X1 [KO:K04498] [EC:2.3.1.48]
107207079  PCGF6; polycomb group RING finger protein 6 [KO:K11470]
107202274  E2F6; transcription factor E2F6 isoform X1 [KO:K09390]
107208664  TFDP1; transcription factor Dp-1 isoform X1 [KO:K04683]
107205598  MAX; protein max isoform X1 [KO:K04453]
107205806  MGA; MAX gene-associated protein isoform X1 [KO:K23399]
107213331  L3MBTL1; lethal(3)malignant brain tumor-like protein 1 isoform X1 [KO:K24387]
107202347  L3MBTL3; lethal(3)malignant brain tumor-like protein 3 isoform X1 [KO:K24387]
107214194  lethal(3)malignant brain tumor-like protein 3 isoform X1 [KO:K24387]
107204834  L3MBTL2; lethal(3)malignant brain tumor-like protein 2 isoform X1 [KO:K24387]
107199827  CBX3; chromobox protein homolog 3 isoform X1 [KO:K11586]
107211986  WDR5; WD repeat-containing protein 5 [KO:K14963]
107202331  HDAC2; histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
107214077  HDAC1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
Reference
PMID:21881606
  Authors
Richly H, Aloia L, Di Croce L
  Title
Roles of the Polycomb group proteins in stem cells and cancer.
  Journal
Cell Death Dis 2:e204 (2011)
DOI:10.1038/cddis.2011.84
Reference
PMID:28202673
  Authors
Chittock EC, Latwiel S, Miller TC, Muller CW
  Title
Molecular architecture of polycomb repressive complexes.
  Journal
Biochem Soc Trans 45:193-205 (2017)
DOI:10.1042/BST20160173
Reference
PMID:33202645
  Authors
Geng Z, Gao Z
  Title
Mammalian PRC1 Complexes: Compositional Complexity and Diverse Molecular Mechanisms.
  Journal
Int J Mol Sci 21:ijms21228594 (2020)
DOI:10.3390/ijms21228594
Reference
PMID:35681061
  Authors
Kim JJ, Kingston RE
  Title
Context-specific Polycomb mechanisms in development.
  Journal
Nat Rev Genet 23:680-695 (2022)
DOI:10.1038/s41576-022-00499-0
Reference
PMID:36076977
  Authors
Dong GJ, Xu JL, Qi YR, Yuan ZQ, Zhao W
  Title
Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer.
  Journal
Int J Mol Sci 23:ijms23179574 (2022)
DOI:10.3390/ijms23179574
Reference
PMID:37086328
  Authors
Ryan CW, Peirent ER, Regan SL, Guxholli A, Bielas SL
  Title
H2A monoubiquitination: insights from human genetics and animal models.
  Journal
Hum Genet 10.1007/s00439-023-02557-x (2023)
DOI:10.1007/s00439-023-02557-x
KO pathway
ko03083   
LinkDB

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