KEGG   PATHWAY: srx03083
Entry
srx03083                    Pathway                                
Name
Polycomb repressive complex - Sinocyclocheilus rhinocerous
Class
Genetic Information Processing; Chromosome
Pathway map
srx03083  Polycomb repressive complex
srx03083

Organism
Sinocyclocheilus rhinocerous [GN:srx]
Gene
107720007  histone-lysine N-methyltransferase EZH1-like [KO:K17451] [EC:2.1.1.356]
107721487  histone-lysine N-methyltransferase EZH1-like isoform X1 [KO:K17451] [EC:2.1.1.356]
107727220  histone-lysine N-methyltransferase EZH2 isoform X1 [KO:K11430] [EC:2.1.1.356]
107741938  histone-lysine N-methyltransferase EZH2-like [KO:K11430] [EC:2.1.1.356]
107751085  polycomb protein eed-like [KO:K11462]
107751659  polycomb protein eed [KO:K11462]
107710288  suz12; polycomb protein SUZ12 [KO:K11463]
107719980  polycomb protein suz12-A [KO:K11463]
107721513  polycomb protein suz12-A-like isoform X1 [KO:K11463]
107710018  polycomb protein suz12-B isoform X1 [KO:K11463]
107709266  histone-binding protein RBBP4-like [KO:K10752]
107724352  histone-binding protein RBBP4 [KO:K10752]
107730765  histone-binding protein RBBP7 isoform X1 [KO:K10752]
107753839  histone-binding protein RBBP7-like isoform X1 [KO:K10752]
107726675  PHD finger protein 1-like isoform X1 [KO:K11467]
107728449  PHD finger protein 1-like [KO:K11467]
107716938  mtf2; metal-response element-binding transcription factor 2 [KO:K11485]
107743365  metal-response element-binding transcription factor 2-like isoform X1 [KO:K11485]
107757290  PHD finger protein 19-like [KO:K11486]
107714156  ligand-dependent corepressor-like [KO:K26260]
107706118  ligand-dependent corepressor-like [KO:K26260]
107708024  zinc finger protein AEBP2-like isoform X1 [KO:K17452]
107718543  zinc finger protein AEBP2 isoform X1 [KO:K17452]
107731546  protein Jumonji-like [KO:K11478]
107714830  protein Jumonji-like [KO:K11478]
107723487  protein Jumonji-like isoform X1 [KO:K11478]
107754814  protein Jumonji [KO:K11478]
107755981  ubiquitin carboxyl-terminal hydrolase BAP1-like [KO:K08588] [EC:3.4.19.12]
107731337  bap1; ubiquitin carboxyl-terminal hydrolase BAP1 [KO:K08588] [EC:3.4.19.12]
107756373  putative Polycomb group protein ASXL1 isoform X1 [KO:K11471]
107741849  putative Polycomb group protein ASXL2 isoform X1 [KO:K11471]
107708815  putative Polycomb group protein ASXL1 isoform X1 [KO:K11471]
107752739  asxl2; putative Polycomb group protein ASXL2 isoform X1 [KO:K11471]
107710944  UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit-like [KO:K09667] [EC:2.4.1.255]
107733421  UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoform X1 [KO:K09667] [EC:2.4.1.255]
107743103  host cell factor 1-like isoform X1 [KO:K14966]
107749508  host cell factor 1-like [KO:K14966]
107727414  host cell factor 1-like isoform X1 [KO:K14966]
107727831  host cell factor 1-like [KO:K14966]
107756049  transcriptional repressor protein YY1-like isoform X1 [KO:K09201]
107719470  transcriptional repressor protein YY1-like [KO:K09201]
107712210  transcriptional repressor protein YY1-like isoform X1 [KO:K09201]
107733162  transcriptional repressor protein YY1-like [KO:K09201]
107705937  mbd5; methyl-CpG-binding domain protein 5 [KO:K23219]
107727035  LOW QUALITY PROTEIN: methyl-CpG-binding domain protein 5-like [KO:K23219]
107758174  methyl-CpG-binding domain protein 6-like [KO:K26585]
107734598  mbd6; methyl-CpG-binding domain protein 6 [KO:K26585]
107718935  forkhead box protein K2-like isoform X1 [KO:K09404]
107719587  forkhead box protein K2-like [KO:K09404]
107720067  forkhead box protein K1-like isoform X1 [KO:K09404]
107748300  forkhead box protein K1-like isoform X1 [KO:K09404]
107706561  forkhead box protein K2-like [KO:K09404]
107710983  forkhead box protein K2-like isoform X1 [KO:K09404]
107718134  E3 ubiquitin-protein ligase RING2 [KO:K10695] [EC:2.3.2.27]
107726161  E3 ubiquitin-protein ligase RING2-A-like isoform X1 [KO:K10695] [EC:2.3.2.27]
107722635  E3 ubiquitin-protein ligase RING2-like [KO:K10695] [EC:2.3.2.27]
107724642  E3 ubiquitin-protein ligase RING2-B-like isoform X1 [KO:K10695] [EC:2.3.2.27]
107741809  polycomb complex protein BMI-1-A-like [KO:K11459]
107718099  polycomb complex protein BMI-1-B-like [KO:K11459]
107722592  polycomb complex protein BMI-1-B [KO:K11459]
107727233  polycomb complex protein BMI-1-A isoform X1 [KO:K11459]
107718939  chromobox protein homolog 2-like [KO:K11451]
107710978  chromobox protein homolog 2-like [KO:K11451]
107710281  cbx4; E3 SUMO-protein ligase CBX4 [KO:K11452] [EC:2.3.2.-]
107736694  E3 SUMO-protein ligase CBX4-like [KO:K11452] [EC:2.3.2.-]
107710010  E3 SUMO-protein ligase CBX4-like [KO:K11452] [EC:2.3.2.-]
107758118  E3 SUMO-protein ligase CBX4-like [KO:K11452] [EC:2.3.2.-]
107728779  E3 SUMO-protein ligase CBX4-like [KO:K11452] [EC:2.3.2.-]
107709653  chromobox protein homolog 7-like [KO:K11454]
107748788  chromobox protein homolog 8-like isoform X1 [KO:K11454]
107723608  chromobox protein homolog 8-like isoform X1 [KO:K11454]
107734182  chromobox protein homolog 7-like [KO:K11454]
107710282  chromobox protein homolog 8-like [KO:K11455]
107710028  chromobox protein homolog 8-like [KO:K11455]
107728583  chromobox protein homolog 8-like [KO:K11455]
107758117  chromobox protein homolog 8-like [KO:K11455]
107714597  polyhomeotic-like protein 1 isoform X1 [KO:K11456]
107724796  polyhomeotic-like protein 1 [KO:K11456]
107708163  polyhomeotic-like protein 2 [KO:K11457]
107729766  polyhomeotic-like protein 2 isoform X1 [KO:K11457]
107737567  polyhomeotic-like protein 2 isoform X1 [KO:K11457]
107706383  polyhomeotic-like protein 3 isoform X1 [KO:K11458]
107738171  polyhomeotic-like protein 3 isoform X1 [KO:K11458]
107737246  polycomb protein SCMH1-like [KO:K11465]
107751164  polycomb protein SCMH1-like [KO:K11465]
107752426  polycomb protein SCMH1-like [KO:K11465]
107748093  sex comb on midleg-like protein 2 [KO:K11465]
107755513  polycomb protein SCMH1-like isoform X1 [KO:K11461]
107705663  polycomb protein SCMH1-like isoform X1 [KO:K11461]
107748479  scm-like with four MBT domains protein 2 [KO:K26269]
107728507  sfmbt2; scm-like with four MBT domains protein 2 isoform X1 [KO:K26269]
107746896  sfmbt1; scm-like with four MBT domains protein 1 [KO:K26269]
107712916  aurora kinase B [KO:K11479] [EC:2.7.11.1]
107717304  aurora kinase B-like [KO:K11479] [EC:2.7.11.1]
107717106  ubiquitin-conjugating enzyme E2 D4-like [KO:K06689] [EC:2.3.2.23]
107718494  ubiquitin-conjugating enzyme E2 D2 [KO:K06689] [EC:2.3.2.23]
107721096  ubiquitin-conjugating enzyme E2 D4 [KO:K06689] [EC:2.3.2.23]
107749768  ubiquitin-conjugating enzyme E2 D2-like isoform X1 [KO:K06689] [EC:2.3.2.23]
107750337  ubiquitin-conjugating enzyme E2 D2-like [KO:K06689] [EC:2.3.2.23]
107708927  ubiquitin-conjugating enzyme E2 D4-like [KO:K06689] [EC:2.3.2.23]
107746458  ubiquitin-conjugating enzyme E2 D4-like [KO:K06689] [EC:2.3.2.23]
107747792  ubiquitin-conjugating enzyme E2 D4 [KO:K06689] [EC:2.3.2.23]
107758532  ubiquitin-conjugating enzyme E2 D2 [KO:K06689] [EC:2.3.2.23]
107733527  ubiquitin-conjugating enzyme E2 D4-like [KO:K06689] [EC:2.3.2.23]
107733771  ubiquitin-conjugating enzyme E2 D2-like isoform X1 [KO:K06689] [EC:2.3.2.23]
107747547  ubiquitin-conjugating enzyme E2 D2-like isoform X1 [KO:K06689] [EC:2.3.2.23]
107711747  ubiquitin carboxyl-terminal hydrolase 45-like [KO:K11844] [EC:3.4.19.12]
107716853  ubiquitin carboxyl-terminal hydrolase 45-like [KO:K11844] [EC:3.4.19.12]
107745176  ubiquitin carboxyl-terminal hydrolase 16-like isoform X1 [KO:K11844] [EC:3.4.19.12]
107705467  ubiquitin carboxyl-terminal hydrolase 16-like isoform X1 [KO:K11844] [EC:3.4.19.12]
107705708  RING1 and YY1-binding protein A-like [KO:K11469]
107732045  RING1 and YY1-binding protein B-like [KO:K11469]
107727016  RING1 and YY1-binding protein A [KO:K11469]
107713516  RING1 and YY1-binding protein B [KO:K11469]
107729839  YY1-associated factor 2-like isoform X1 [KO:K11468]
107725590  YY1-associated factor 2-like isoform X1 [KO:K11468]
107710472  polycomb group RING finger protein 1 isoform X1 [KO:K11487]
107705480  polycomb group RING finger protein 1-like [KO:K11487]
107758663  kdm2b; lysine-specific demethylase 2B [KO:K10276] [EC:1.14.11.27]
107712479  lysine-specific demethylase 2B-like isoform X1 [KO:K10276] [EC:1.14.11.27]
107746202  lysine-specific demethylase 2B-like [KO:K10276] [EC:1.14.11.27]
107742705  lysine-specific demethylase 2A-like [KO:K10276] [EC:1.14.11.27]
107753096  lysine-specific demethylase 2B-like isoform X1 [KO:K10276] [EC:1.14.11.27]
107754453  lysine-specific demethylase 2A-like isoform X1 [KO:K10276] [EC:1.14.11.27]
107746404  lysine-specific demethylase 2A-like isoform X1 [KO:K10276] [EC:1.14.11.27]
107756025  BCL-6 corepressor-like [KO:K23215]
107745971  BCL-6 corepressor-like isoform X1 [KO:K23215]
107740161  BCL-6 corepressor-like protein 1 isoform X1 [KO:K26199]
107724841  BCL-6 corepressor-like protein 1 isoform X1 [KO:K26199]
107742439  skp1; S-phase kinase-associated protein 1 [KO:K03094]
107728271  S-phase kinase-associated protein 1 [KO:K03094]
107733822  ubiquitin carboxyl-terminal hydrolase 7-like [KO:K11838] [EC:3.4.19.12]
107738626  usp7; ubiquitin carboxyl-terminal hydrolase 7 isoform X1 [KO:K11838] [EC:3.4.19.12]
107750320  polycomb group RING finger protein 3-like [KO:K11488]
107751329  polycomb group RING finger protein 3 [KO:K11488]
107715951  polycomb group RING finger protein 5-A-like isoform X1 [KO:K11489]
107758437  polycomb group RING finger protein 5-B-like [KO:K11489]
107744529  polycomb group RING finger protein 5-A [KO:K11489]
107753439  polycomb group RING finger protein 5-B isoform X1 [KO:K11489]
107754820  casein kinase II subunit beta [KO:K03115]
107711319  casein kinase II subunit beta [KO:K03115]
107718788  autism susceptibility gene 2 protein-like [KO:K23214]
107720532  autism susceptibility gene 2 protein-like [KO:K23214]
107707850  autism susceptibility gene 2 protein-like [KO:K23214]
107726097  autism susceptibility gene 2 protein-like isoform X1 [KO:K23214]
107729123  autism susceptibility gene 2 protein-like isoform X1 [KO:K23214]
107747043  autism susceptibility gene 2 protein-like [KO:K23214]
107706892  autism susceptibility gene 2 protein-like isoform X1 [KO:K26253]
107727304  autism susceptibility gene 2 protein-like isoform X1 [KO:K26253]
107707821  fibrosin-1-like protein [KO:K26254]
107741284  autism susceptibility gene 2 protein-like [KO:K26254]
107721959  DDB1- and CUL4-associated factor 7-like [KO:K11805]
107729536  dcaf7; DDB1- and CUL4-associated factor 7 isoform X1 [KO:K11805]
107706105  testis-expressed sequence 10 protein homolog [KO:K14827]
107723457  testis-expressed sequence 10 protein homolog [KO:K14827]
107755349  CREB-binding protein-like isoform X1 [KO:K04498] [EC:2.3.1.48]
107723602  histone acetyltransferase p300-like isoform X1 [KO:K04498] [EC:2.3.1.48]
107709650  histone acetyltransferase p300-like isoform X1 [KO:K04498] [EC:2.3.1.48]
107718619  CREB-binding protein-like [KO:K04498] [EC:2.3.1.48]
107715623  CREB-binding protein-like [KO:K04498] [EC:2.3.1.48]
107742089  CREB-binding protein-like isoform X1 [KO:K04498] [EC:2.3.1.48]
107734181  LOW QUALITY PROTEIN: histone acetyltransferase p300-like [KO:K04498] [EC:2.3.1.48]
107748789  histone acetyltransferase p300-like [KO:K04498] [EC:2.3.1.48]
107716281  polycomb group RING finger protein 6-like [KO:K11470]
107707701  polycomb group RING finger protein 6-like isoform X1 [KO:K11470]
107721299  transcription factor E2f1-like [KO:K09390]
107756581  uncharacterized protein LOC107756581 isoform X1 [KO:K09390]
107748134  transcription factor Dp-1-like [KO:K04683]
107756763  transcription factor Dp-1-like [KO:K04683]
107748334  transcription factor Dp-1-like isoform X1 [KO:K04683]
107751069  transcription factor Dp-1-like isoform X1 [KO:K04683]
107721316  protein max-like isoform X1 [KO:K04453]
107756603  protein max isoform X1 [KO:K04453]
107725733  MAX gene-associated protein-like [KO:K23399]
107729276  MAX gene-associated protein-like isoform X1 [KO:K23399]
107756045  MAX gene-associated protein-like isoform X1 [KO:K23399]
107711611  lethal(3)malignant brain tumor-like protein 3 [KO:K24387]
107714262  lethal(3)malignant brain tumor-like protein 1 [KO:K24387]
107706333  lethal(3)malignant brain tumor-like protein 4 [KO:K24387]
107723564  lethal(3)malignant brain tumor-like protein 4 isoform X1 [KO:K24387]
107709654  lethal(3)malignant brain tumor-like protein 2 [KO:K24387]
107736954  lethal(3)malignant brain tumor-like protein 1 isoform X1 [KO:K24387]
107740526  lethal(3)malignant brain tumor-like protein 3 [KO:K24387]
107734235  lethal(3)malignant brain tumor-like protein 2 [KO:K24387]
107728996  lethal(3)malignant brain tumor-like protein 4 [KO:K24387]
107710359  chromobox protein homolog 3-like [KO:K11586]
107743152  chromobox protein homolog 3-like [KO:K11586]
107744695  chromobox protein homolog 3-like [KO:K11586]
107748667  chromobox protein homolog 3-like [KO:K11586]
107708358  WD repeat-containing protein 5 [KO:K14963]
107731009  WD repeat-containing protein 5-like [KO:K14963]
107741954  WD repeat-containing protein 5 [KO:K14963]
107740805  WD repeat-containing protein 5-like [KO:K14963]
107709289  probable histone deacetylase 1-B isoform X1 [KO:K06067] [EC:3.5.1.98]
107745719  probable histone deacetylase 1-B isoform X1 [KO:K06067] [EC:3.5.1.98]
Reference
PMID:21881606
  Authors
Richly H, Aloia L, Di Croce L
  Title
Roles of the Polycomb group proteins in stem cells and cancer.
  Journal
Cell Death Dis 2:e204 (2011)
DOI:10.1038/cddis.2011.84
Reference
PMID:28202673
  Authors
Chittock EC, Latwiel S, Miller TC, Muller CW
  Title
Molecular architecture of polycomb repressive complexes.
  Journal
Biochem Soc Trans 45:193-205 (2017)
DOI:10.1042/BST20160173
Reference
PMID:33202645
  Authors
Geng Z, Gao Z
  Title
Mammalian PRC1 Complexes: Compositional Complexity and Diverse Molecular Mechanisms.
  Journal
Int J Mol Sci 21:ijms21228594 (2020)
DOI:10.3390/ijms21228594
Reference
PMID:35681061
  Authors
Kim JJ, Kingston RE
  Title
Context-specific Polycomb mechanisms in development.
  Journal
Nat Rev Genet 23:680-695 (2022)
DOI:10.1038/s41576-022-00499-0
Reference
PMID:36076977
  Authors
Dong GJ, Xu JL, Qi YR, Yuan ZQ, Zhao W
  Title
Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer.
  Journal
Int J Mol Sci 23:ijms23179574 (2022)
DOI:10.3390/ijms23179574
Reference
PMID:37086328
  Authors
Ryan CW, Peirent ER, Regan SL, Guxholli A, Bielas SL
  Title
H2A monoubiquitination: insights from human genetics and animal models.
  Journal
Hum Genet 10.1007/s00439-023-02557-x (2023)
DOI:10.1007/s00439-023-02557-x
KO pathway
ko03083   
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