KEGG   PATHWAY: vam00630
Entry
vam00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Variovorax sp. PMC12
Class
Metabolism; Carbohydrate metabolism
Pathway map
vam00630  Glyoxylate and dicarboxylate metabolism
vam00630

Module
vam_M00012  Glyoxylate cycle [PATH:vam00630]
vam_M00621  Glycine cleavage system [PATH:vam00630]
Other DBs
GO: 0046487 0043648
Organism
Variovorax sp. PMC12 [GN:vam]
Gene
C4F17_08500  isocitrate lyase [KO:K01637] [EC:4.1.3.1 4.1.3.30]
C4F17_07010  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
C4F17_32055  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
C4F17_16440  malate synthase G [KO:K01638] [EC:2.3.3.9]
C4F17_11260  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
C4F17_11990  citryl-CoA lyase [KO:K01647] [EC:2.3.3.1]
C4F17_20640  citrate synthase [KO:K01647] [EC:2.3.3.1]
C4F17_20645  citrate synthase/methylcitrate synthase [KO:K01647] [EC:2.3.3.1]
C4F17_11295  gltA; citrate (Si)-synthase [KO:K01647] [EC:2.3.3.1]
C4F17_06080  2-methylcitrate synthase [KO:K01659] [EC:2.3.3.5]
C4F17_11220  acnA; aconitate hydratase [KO:K27802] [EC:4.2.1.3 4.2.1.99]
C4F17_11240  bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase [KO:K01682] [EC:4.2.1.3 4.2.1.99]
C4F17_00650  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
C4F17_04585  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
C4F17_14975  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
C4F17_22400  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
C4F17_30720  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
C4F17_30855  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
C4F17_16475  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
C4F17_14130  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
C4F17_22880  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
C4F17_31685  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
C4F17_02295  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
C4F17_02355  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
C4F17_32295  beta-ketoacyl-ACP reductase [KO:K00023] [EC:1.1.1.36]
C4F17_02765  accC; acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01965] [EC:6.4.1.3]
C4F17_02760  acyl-CoA carboxylase subunit beta [KO:K01966] [EC:6.4.1.3 2.1.3.15]
C4F17_20360  acetyl/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.4.1.- 6.3.4.14]
C4F17_02745  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
C4F17_17715  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
C4F17_17710  glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
C4F17_17705  glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
C4F17_16200  catalase HPII [KO:K03781] [EC:1.11.1.6]
C4F17_28850  catalase HPII [KO:K03781] [EC:1.11.1.6]
C4F17_22510  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
C4F17_28550  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
C4F17_01300  glyoxylate/hydroxypyruvate reductase A [KO:K12972] [EC:1.1.1.79 1.1.1.81]
C4F17_00290  D-glycerate dehydrogenase [KO:K00090] [EC:1.1.1.79 1.1.1.81 1.1.1.215]
C4F17_11515  HAD family hydrolase [KO:K01091] [EC:3.1.3.18]
C4F17_15885  phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
C4F17_04690  serine--glyoxylate aminotransferase [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
C4F17_26650  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
C4F17_18175  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
C4F17_14535  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
C4F17_07645  glyA; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
C4F17_01700  glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
C4F17_01710  gcvT; glycine cleavage system aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
C4F17_02930  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
C4F17_02975  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
C4F17_01705  gcvH; glycine cleavage system protein H [KO:K02437]
C4F17_30115  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
C4F17_30110  hyi; hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
C4F17_30105  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
C4F17_30200  glycerate kinase [KO:K11529] [EC:2.7.1.165]
C4F17_19345  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
C4F17_28590  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
C4F17_10280  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
C4F17_00355  tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
C4F17_09975  keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
C4F17_25365  fdnG; formate dehydrogenase-N subunit alpha [KO:K00123] [EC:1.17.1.9]
C4F17_25370  sulfate ABC transporter substrate-binding protein [KO:K00123] [EC:1.17.1.9]
C4F17_25360  fdxH; formate dehydrogenase subunit beta [KO:K00124]
C4F17_25355  formate dehydrogenase subunit gamma [KO:K00127]
C4F17_10770  esterase [KO:K01432] [EC:3.5.1.9]
C4F17_06335  esterase [KO:K01432] [EC:3.5.1.9]
C4F17_11155  kynB; arylformamidase [KO:K07130] [EC:3.5.1.9]
C4F17_22070  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
C4F17_17425  amiF; formamidase [KO:K01455] [EC:3.5.1.49]
C4F17_07870  acetamidase/formamidase family protein [KO:K01455] [EC:3.5.1.49]
C4F17_18005  hutG; N-formylglutamate deformylase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
vam00010  Glycolysis / Gluconeogenesis
vam00020  Citrate cycle (TCA cycle)
vam00030  Pentose phosphate pathway
vam00053  Ascorbate and aldarate metabolism
vam00071  Fatty acid degradation
vam00230  Purine metabolism
vam00250  Alanine, aspartate and glutamate metabolism
vam00260  Glycine, serine and threonine metabolism
vam00620  Pyruvate metabolism
vam00710  Carbon fixation by Calvin cycle
vam00750  Vitamin B6 metabolism
vam00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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