KEGG   PATHWAY: pga00630
Entry
pga00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Phaeobacter inhibens DSM 17395
Class
Metabolism; Carbohydrate metabolism
Pathway map
pga00630  Glyoxylate and dicarboxylate metabolism
pga00630

Module
pga_M00621  Glycine cleavage system [PATH:pga00630]
pga_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:pga00630]
Other DBs
GO: 0046487 0043648
Organism
Phaeobacter inhibens DSM 17395 [GN:pga]
Gene
PGA1_78p00260  lpdA; dihydrolipoyl dehydrogenase LpdA [KO:K00382] [EC:1.8.1.4]
PGA1_78p00290  gcvT; aminomethyltransferase GcvT [KO:K00605] [EC:2.1.2.10]
PGA1_78p00300  gcvH; glycine cleavage system protein GcvH [KO:K02437]
PGA1_78p00310  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
PGA1_c01110  [KO:K14448] [EC:1.3.8.12]
PGA1_c01960  [KO:K01091] [EC:3.1.3.18]
PGA1_c03390  phaB; acetoacetyl-CoA reductase PhaB [KO:K00023] [EC:1.1.1.36]
PGA1_c03400  phaA; acetyl-CoA acetyltransferase PhaA [KO:K00626] [EC:2.3.1.9]
PGA1_c03550  lpd2; dihydrolipoyl dehydrogenase 2 [KO:K00382] [EC:1.8.1.4]
PGA1_c03650  mdh; malate dehydrogenase Mdh [KO:K00024] [EC:1.1.1.37]
PGA1_c03680  [KO:K14451] [EC:3.1.2.30]
PGA1_c03710  [KO:K14449] [EC:4.2.1.148]
PGA1_c03840  mutB; methylmalonyl-CoA mutase large subunit [KO:K14447] [EC:5.4.99.63]
PGA1_c03870  [KO:K14446] [EC:1.3.1.85]
PGA1_c05550  [KO:K01915] [EC:6.3.1.2]
PGA1_c05560  gcvH; glycine cleavage system protein GcvH [KO:K02437]
PGA1_c08560  [KO:K01091] [EC:3.1.3.18]
PGA1_c09900  glcB; malate synthase GlcB [KO:K01638] [EC:2.3.3.9]
PGA1_c10250  [KO:K01091] [EC:3.1.3.18]
PGA1_c10300  acsA; acetyl-coenzyme A synthetase AcsA [KO:K01895] [EC:6.2.1.1]
PGA1_c11520  puuA1; gamma-glutamylputrescine synthetase PuuA [KO:K01915] [EC:6.3.1.2]
PGA1_c11540  puuA2; gamma-glutamylputrescine synthetase PuuA [KO:K01915] [EC:6.3.1.2]
PGA1_c11870  glyA; serine hydroxymethyltransferase GlyA [KO:K00600] [EC:2.1.2.1]
PGA1_c12030  fadA2; 3-ketoacyl-CoA thiolase FadA [KO:K00626] [EC:2.3.1.9]
PGA1_c12950  acs; acetyl-coenzyme A synthetase Acs [KO:K01895] [EC:6.2.1.1]
PGA1_c16970  gltA1; citrate synthase GltA [KO:K01647] [EC:2.3.3.1]
PGA1_c17390  lpdA2; dihydrolipoyl dehydrogenase LpdA [KO:K00382] [EC:1.8.1.4]
PGA1_c17990  dmlA; D-malate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
PGA1_c18720  glnA; glutamine synthetase GlnA [KO:K01915] [EC:6.3.1.2]
PGA1_c18830  acnA; aconitate hydratase AcnA [KO:K27802]
PGA1_c21510  bhbA; methylmalonyl-CoA mutase BhbA [KO:K01847] [EC:5.4.99.2]
PGA1_c21540  pccA; propionyl-CoA carboxylase alpha chain [KO:K01965] [EC:6.4.1.3]
PGA1_c21600  pccB; propionyl-CoA carboxylase beta chain [KO:K01966] [EC:6.4.1.3 2.1.3.15]
PGA1_c23190  lpdA3; dihydrolipoyl dehydrogenase LpdA [KO:K00382] [EC:1.8.1.4]
PGA1_c23340  [KO:K01915] [EC:6.3.1.2]
PGA1_c23940  [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
PGA1_c24490  [KO:K05606] [EC:5.1.99.1]
PGA1_c24580  [KO:K00600] [EC:2.1.2.1]
PGA1_c24980  [KO:K17865] [EC:4.2.1.55]
PGA1_c25740  fdhF; formate dehydrogenase H [KO:K00123] [EC:1.17.1.9]
PGA1_c25750  nuoEF; NADH-quinone oxidoreductase subunits E/F (fused) [KO:K22515] [EC:1.17.1.9]
PGA1_c26570  [KO:K12972] [EC:1.1.1.79 1.1.1.81]
PGA1_c27180  [KO:K01915] [EC:6.3.1.2]
PGA1_c27630  [KO:K00127]
PGA1_c27640  fdhB; formate dehydrogenase iron-sulfur subunit [KO:K00124]
PGA1_c27650  [KO:K00123] [EC:1.17.1.9]
PGA1_c28010  eda; KHG/KDPG aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
PGA1_c28260  gyaR2; glyoxylate reductase GyaR [KO:K00015] [EC:1.1.1.26]
PGA1_c28860  gltA2; citrate synthase GltA [KO:K01659] [EC:2.3.3.5]
PGA1_c29700  glcF; glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
PGA1_c29710  glcE; glycolate oxidase subunit GlcE [KO:K11472] [EC:1.1.99.14]
PGA1_c29720  glcD; glycolate oxidase subunit GlcD [KO:K00104] [EC:1.1.99.14]
PGA1_c30490  [KO:K08691] [EC:4.1.3.24 4.1.3.25]
PGA1_c31360  [KO:K11529] [EC:2.7.1.165]
PGA1_c33180  [KO:K00626] [EC:2.3.1.9]
PGA1_c34350  phbA; acetyl-CoA acetyltransferase PhbA [KO:K00626] [EC:2.3.1.9]
PGA1_c36330  hutG; N-formylglutamate deformylase HutG [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00049  L-Aspartate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C05840  Iminoaspartate
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C19838  D-erythro-3-Hydroxyaspartate
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
pga00010  Glycolysis / Gluconeogenesis
pga00020  Citrate cycle (TCA cycle)
pga00030  Pentose phosphate pathway
pga00053  Ascorbate and aldarate metabolism
pga00071  Fatty acid degradation
pga00230  Purine metabolism
pga00250  Alanine, aspartate and glutamate metabolism
pga00260  Glycine, serine and threonine metabolism
pga00270  Cysteine and methionine metabolism
pga00620  Pyruvate metabolism
pga00710  Carbon fixation by Calvin cycle
pga00750  Vitamin B6 metabolism
pga00910  Nitrogen metabolism
KO pathway
ko00630   

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