KEGG   PATHWAY: rlw00230
Entry
rlw00230                    Pathway                                
Name
Purine metabolism - Rhizobium laguerreae
Class
Metabolism; Nucleotide metabolism
Pathway map
rlw00230  Purine metabolism
rlw00230

Module
rlw_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:rlw00230]
rlw_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:rlw00230]
rlw_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:rlw00230]
rlw_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:rlw00230]
rlw_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:rlw00230]
rlw_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:rlw00230]
rlw_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:rlw00230]
Other DBs
GO: 0006163 0042278
Organism
Rhizobium laguerreae [GN:rlw]
Gene
RlegWSM1455_22690  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
RlegWSM1455_18455  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
RlegWSM1455_15200  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
RlegWSM1455_05985  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
RlegWSM1455_02750  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
RlegWSM1455_06240  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
RlegWSM1455_10820  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
RlegWSM1455_10790  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
RlegWSM1455_10795  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
RlegWSM1455_06245  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
RlegWSM1455_18090  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
RlegWSM1455_18085  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
RlegWSM1455_17445  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
RlegWSM1455_10785  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
RlegWSM1455_10760  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
RlegWSM1455_21260  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
RlegWSM1455_15260  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
RlegWSM1455_18235  5'-nucleotidase C-terminal domain-containing protein [KO:K11751] [EC:3.1.3.5 3.6.1.45]
RlegWSM1455_08405  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
RlegWSM1455_22660  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
RlegWSM1455_15185  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
RlegWSM1455_19505  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
RlegWSM1455_02220  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
RlegWSM1455_06155  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
RlegWSM1455_00020  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
RlegWSM1455_07915  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
RlegWSM1455_15710  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
RlegWSM1455_15715  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
RlegWSM1455_25170  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
RlegWSM1455_09450  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
RlegWSM1455_32255  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
RlegWSM1455_25175  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
RlegWSM1455_32260  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
RlegWSM1455_25180  paoA; aldehyde dehydrogenase iron-sulfur subunit [KO:K13483]
RlegWSM1455_32265  (2Fe-2S)-binding protein [KO:K13483]
RlegWSM1455_20190  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
RlegWSM1455_22960  type 1 glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
RlegWSM1455_23370  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
RlegWSM1455_15750  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
RlegWSM1455_06070  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
RlegWSM1455_19135  nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
RlegWSM1455_07905  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
RlegWSM1455_19130  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
RlegWSM1455_08355  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
RlegWSM1455_05870  HD family hydrolase [KO:K06952] [EC:3.1.3.89]
RlegWSM1455_05780  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
RlegWSM1455_02195  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
RlegWSM1455_06265  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
RlegWSM1455_13615  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_14190  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_17175  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_17180  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_18400  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_18505  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_18510  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_19015  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_19125  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_29395  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_29455  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_00440  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_04200  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_06275  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_09925  tetratricopeptide repeat protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_10260  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_11955  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_12075  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_12545  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_12550  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_13530  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_03710  response regulator [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_03935  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_23615  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
RlegWSM1455_16840  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
RlegWSM1455_22685  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
RlegWSM1455_05620  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
RlegWSM1455_15565  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
RlegWSM1455_17475  adenine deaminase [KO:K01486] [EC:3.5.4.2]
RlegWSM1455_20130  amidohydrolase family protein [KO:K01486] [EC:3.5.4.2]
RlegWSM1455_08205  amidohydrolase family protein [KO:K01486] [EC:3.5.4.2]
RlegWSM1455_07985  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
RlegWSM1455_17745  TIGR00282 family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
RlegWSM1455_07525  adenylate kinase [KO:K00939] [EC:2.7.4.3]
RlegWSM1455_09095  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
RlegWSM1455_04470  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
RlegWSM1455_04475  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
RlegWSM1455_33390  NAD(P)/FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
RlegWSM1455_15800  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
RlegWSM1455_14680  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
RlegWSM1455_23890  amidohydrolase family protein [KO:K01466] [EC:3.5.2.5]
RlegWSM1455_15820  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
RlegWSM1455_30840  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
RlegWSM1455_15805  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
RlegWSM1455_16635  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
RlegWSM1455_16660  urease subunit beta [KO:K01429] [EC:3.5.1.5]
RlegWSM1455_16670  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
rlw00030  Pentose phosphate pathway
rlw00220  Arginine biosynthesis
rlw00250  Alanine, aspartate and glutamate metabolism
rlw00260  Glycine, serine and threonine metabolism
rlw00340  Histidine metabolism
rlw00630  Glyoxylate and dicarboxylate metabolism
rlw00730  Thiamine metabolism
rlw00740  Riboflavin metabolism
rlw00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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