KEGG   PATHWAY: sil00630
Entry
sil00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Ruegeria pomeroyi
Class
Metabolism; Carbohydrate metabolism
Pathway map
sil00630  Glyoxylate and dicarboxylate metabolism
sil00630

Module
sil_M00373  Ethylmalonyl pathway [PATH:sil00630]
sil_M00621  Glycine cleavage system [PATH:sil00630]
sil_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:sil00630]
Other DBs
GO: 0046487 0043648
Organism
Ruegeria pomeroyi [GN:sil]
Gene
SPO2791  acsA; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
SPO1813  acs; acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
SPO2839  glcB; malate synthase G [KO:K01638] [EC:2.3.3.9]
SPO0349  mdh; malate dehydrogenase, NAD-dependent [KO:K00024] [EC:1.1.1.37]
SPO2157  gltA; citrate synthase I [KO:K01647] [EC:2.3.3.1]
SPO2312  acnA; aconitate hydratase 1 [KO:K01681] [EC:4.2.1.3]
SPO1569  malate--CoA ligase, alpha subunit [KO:K08692] [EC:6.2.1.9]
SPO1568  malate--CoA ligase, beta subunit [KO:K14067] [EC:6.2.1.9]
SPO0142  bktB; beta-ketothiolase [KO:K00626] [EC:2.3.1.9]
SPO3408  acetyl-CoA C-acetyltransferase [KO:K00626] [EC:2.3.1.9]
SPO0773  acetyl-CoA acyltransferase/thiolase family protein [KO:K00626] [EC:2.3.1.9]
SPO0326  phbA; acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
SPO2918  acetyl-CoA acyltransferase/thiolase [KO:K00626] [EC:2.3.1.9]
SPOA0425  acetyl-CoA acyltransferase/thiolase [KO:K00626] [EC:2.3.1.9]
SPO1013  thiolase family protein [KO:K00626] [EC:2.3.1.9]
SPO0325  phbB; acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
SPO3152  MaoC domain protein [KO:K17865] [EC:4.2.1.55]
SPO0370  ccrA; crotonyl-CoA reductase [KO:K14446] [EC:1.3.1.85]
SPO0932  methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
SPO0368  methylmalonyl-CoA mutase [KO:K14447] [EC:5.4.99.63]
SPO0693  isobutyryl-CoA dehydrogenase [KO:K14448] [EC:1.3.8.12]
SPO0355  hypothetical protein [KO:K14449] [EC:4.2.1.148]
SPO1565  citrate lyase, putative [KO:K08691] [EC:4.1.3.24 4.1.3.25]
SPO3608  mclA; malyl-CoA lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
SPO0352  citE; citrate lyase, beta subunit [KO:K14451] [EC:3.1.2.30]
SPO1101  pccA; propionyl-CoA carboxylase, alpha subunit [KO:K01965] [EC:6.4.1.3]
SPO1094  pccB; propionyl-CoA carboxylase, beta subunit [KO:K01966] [EC:6.4.1.3 2.1.3.15]
SPO1105  methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
SPO3478  glcD; glycolate oxidase, GlcD subunit [KO:K00104] [EC:1.1.99.14]
SPO3479  glcE; glycolate oxidase, GlcE subunit [KO:K11472] [EC:1.1.99.14]
SPO3480  glcF; glycolate oxidase, iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
SPO0632  D-isomer specific 2-hydroxyacid dehydrogenase family protein [KO:K00015] [EC:1.1.1.26]
SPO0415  D-isomer specific 2-hydroxyacid dehydrogenase family protein [KO:K12972] [EC:1.1.1.79 1.1.1.81]
SPO2751  HAD-superfamily hydrolase, subfamily IA, variant 1 family protein [KO:K01091] [EC:3.1.3.18]
SPO0517  HAD-superfamily hydrolase, subfamily IA, variant 1 [KO:K01091] [EC:3.1.3.18]
SPO2796  gph-2; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
SPO0787  gph-1; phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
SPO3029  serine--glyoxylate transaminase, putative [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
SPOA0144  serine--glyoxylate transaminase, putative [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
SPO2607  gamma-glutamylisopropylamide synthetase, putative [KO:K01915] [EC:6.3.1.2]
SPO1300  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
SPO1302  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
SPO0765  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
SPO1825  glutamine synthetase family protein [KO:K01915] [EC:6.3.1.2]
SPO2295  glnA; glutamine synthetase, type I [KO:K01915] [EC:6.3.1.2]
SPO3529  glyA-3; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SPO2940  glyA-2; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SPO1572  glyA-1; serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
SPOA0059  gcvP; glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
SPO1562  glycine cleavage system T protein, putative [KO:K00605] [EC:2.1.2.10]
SPOA0057  gcvT; glycine cleavage system T protein [KO:K00605] [EC:2.1.2.10]
SPO1579  aminomethyl transferase family protein [KO:K00605] [EC:2.1.2.10]
SPO2222  pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase, putative [KO:K00382] [EC:1.8.1.4]
SPO0340  lpdA; 2-oxoglutarate dehydrogenase, E3 component, dihydrolipoamide dehydrogenase [KO:K00382] [EC:1.8.1.4]
SPO0878  gcvH-1; glycine cleavage system H protein [KO:K02437]
SPOA0058  gcvH-2; glycine cleavage system H protein [KO:K02437]
SPO1564  MOFRL domain protein [KO:K11529] [EC:2.7.1.165]
SPO2993  MOFRL family protein [KO:K11529] [EC:2.7.1.165]
SPOA0330  eda-2; 2-dehydro-3-deoxyphosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SPO3031  eda-1; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
SPO1796  formate dehydrogenase, alpha subunit, putative [KO:K00123] [EC:1.17.1.9]
SPO1556  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
SPO0834  formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
SPO1555  formate dehydrogenase, beta subunit [KO:K22515] [EC:1.17.1.9]
SPO0833  formate dehydrogenase, beta subunit [KO:K22515] [EC:1.17.1.9]
SPO1795  formate dehydrogenase, iron-sulfur subunit, putative [KO:K00124]
SPO1794  formate dehydrogenase, gamma subunit [KO:K00127]
SPOA0408  hypothetical protein [KO:K01432] [EC:3.5.1.9]
SPO2192a  hutG; N-formylglutamate amidohydrolase [KO:K01458] [EC:3.5.1.68]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sil00010  Glycolysis / Gluconeogenesis
sil00020  Citrate cycle (TCA cycle)
sil00030  Pentose phosphate pathway
sil00053  Ascorbate and aldarate metabolism
sil00071  Fatty acid degradation
sil00230  Purine metabolism
sil00250  Alanine, aspartate and glutamate metabolism
sil00260  Glycine, serine and threonine metabolism
sil00620  Pyruvate metabolism
sil00710  Carbon fixation by Calvin cycle
sil00750  Vitamin B6 metabolism
sil00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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