KEGG   PATHWAY: spu00330
Entry
spu00330                    Pathway                                
Name
Arginine and proline metabolism - Strongylocentrotus purpuratus (purple sea urchin)
Class
Metabolism; Amino acid metabolism
Pathway map
spu00330  Arginine and proline metabolism
spu00330

Module
spu_M00015  Proline biosynthesis, glutamate => proline [PATH:spu00330]
spu_M00047  Creatine pathway [PATH:spu00330]
spu_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:spu00330]
spu_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:spu00330]
spu_M00970  Proline degradation, proline => glutamate [PATH:spu00330]
spu_M00972  Proline metabolism [PATH:spu00330]
Other DBs
GO: 0006525 0006560
Organism
Strongylocentrotus purpuratus (purple sea urchin) [GN:spu]
Gene
581473  glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
578397  guanidinoacetate N-methyltransferase isoform X1 [KO:K00542] [EC:2.1.1.2]
115919361  guanidinoacetate N-methyltransferase-like [KO:K00542] [EC:2.1.1.2]
762696  LOW QUALITY PROTEIN: arginine kinase [KO:K00933] [EC:2.7.3.2]
589605  creatine kinase U-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
115919532  creatine kinase B-type-like [KO:K00933] [EC:2.7.3.2]
581883  creatine kinase U-type, mitochondrial-like [KO:K00933] [EC:2.7.3.2]
580962  LOW QUALITY PROTEIN: arginine kinase [KO:K00933] [EC:2.7.3.2]
589060  ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
105439774  ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
591935  spermidine synthase [KO:K00797] [EC:2.5.1.16]
584264  spermine synthase [KO:K00802] [EC:2.5.1.22]
115919270  spermine synthase-like [KO:K00802] [EC:2.5.1.22]
756698  S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
581754  aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
581706  aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
105445554  aldehyde dehydrogenase, dimeric NADP-preferring [KO:K00128] [EC:1.2.1.3]
593236  aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
105445170  aldehyde dehydrogenase family 3 member A2 isoform X1 [KO:K00128] [EC:1.2.1.3]
756945  aldehyde dehydrogenase, dimeric NADP-preferring [KO:K00128] [EC:1.2.1.3]
588376  alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
580956  4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
583864  4-trimethylaminobutyraldehyde dehydrogenase A [KO:K00149] [EC:1.2.1.47 1.2.1.3]
115918585  4-trimethylaminobutyraldehyde dehydrogenase-like [KO:K00149] [EC:1.2.1.47 1.2.1.3]
594228  cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
591752  diamine acetyltransferase 2 [KO:K00657] [EC:2.3.1.57]
100888217  diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
115922474  diamine acetyltransferase 2-like [KO:K00657] [EC:2.3.1.57]
105438354  diamine acetyltransferase 2-like [KO:K00657] [EC:2.3.1.57]
115922646  diamine acetyltransferase 2-like [KO:K00657] [EC:2.3.1.57]
100893060  diamine acetyltransferase 2 [KO:K00657] [EC:2.3.1.57]
115924931  diamine acetyltransferase 2-like [KO:K00657] [EC:2.3.1.57]
100890768  diamine acetyltransferase 2 [KO:K00657] [EC:2.3.1.57]
105439334  diamine acetyltransferase 2-like [KO:K00657] [EC:2.3.1.57]
115919384  diamine acetyltransferase 2-like [KO:K00657] [EC:2.3.1.57]
575578  diamine acetyltransferase 2 [KO:K00657] [EC:2.3.1.57]
592766  diamine acetyltransferase 2 [KO:K00657] [EC:2.3.1.57]
590013  amine oxidase [flavin-containing] B [KO:K00274] [EC:1.4.3.4]
115918590  probable flavin-containing monoamine oxidase A [KO:K00274] [EC:1.4.3.4]
583484  probable flavin-containing monoamine oxidase A isoform X1 [KO:K00274] [EC:1.4.3.4]
590198  probable flavin-containing monoamine oxidase A [KO:K00274] [EC:1.4.3.4]
100891493  amine oxidase [flavin-containing] B [KO:K00274] [EC:1.4.3.4]
105443950  amine oxidase [flavin-containing] B-like [KO:K00274] [EC:1.4.3.4]
115922594  uncharacterized protein LOC115922594 [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
115922848  uncharacterized protein LOC115922848 [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
577889  agmatinase, mitochondrial [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
590928  uncharacterized protein LOC590928 [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
115922593  uncharacterized protein LOC115922593 [KO:K27001] [EC:3.5.3.- 3.5.3.7 3.5.3.17]
100892264  uncharacterized protein LOC100892264 [KO:K01426] [EC:3.5.1.4]
578788  uncharacterized protein LOC578788 [KO:K01426] [EC:3.5.1.4]
100890319  uncharacterized protein LOC100890319 [KO:K01426] [EC:3.5.1.4]
576789  uncharacterized protein LOC576789 [KO:K01426] [EC:3.5.1.4]
115918304  uncharacterized protein LOC115918304 [KO:K01426] [EC:3.5.1.4]
576856  uncharacterized protein LOC576856 [KO:K01426] [EC:3.5.1.4]
105443268  uncharacterized protein LOC105443268 [KO:K01426] [EC:3.5.1.4]
100889766  uncharacterized protein LOC100889766 [KO:K01426] [EC:3.5.1.4]
578947  uncharacterized protein LOC578947 [KO:K01426] [EC:3.5.1.4]
588819  uncharacterized protein LOC588819 [KO:K01426] [EC:3.5.1.4]
577145  uncharacterized protein LOC577145 isoform X1 [KO:K01426] [EC:3.5.1.4]
100888109  nitric oxide synthase, brain isoform X1 [KO:K13240] [EC:1.14.13.39]
587111  nitric oxide synthase, endothelial [KO:K13240] [EC:1.14.13.39]
586250  arginase-1 [KO:K01476] [EC:3.5.3.1]
593316  LOW QUALITY PROTEIN: ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
115924209  ornithine aminotransferase, mitochondrial-like [KO:K00819] [EC:2.6.1.13]
583853  pyrroline-5-carboxylate reductase 1, mitochondrial [KO:K00286] [EC:1.5.1.2]
586502  pyrroline-5-carboxylate reductase 3 isoform X1 [KO:K00286] [EC:1.5.1.2]
115923412  LOW QUALITY PROTEIN: pyrroline-5-carboxylate reductase 1, mitochondrial-like [KO:K00286] [EC:1.5.1.2]
583871  pyrroline-5-carboxylate reductase 1, mitochondrial [KO:K00286] [EC:1.5.1.2]
583929  proline dehydrogenase 1, mitochondrial [KO:K00318] [EC:1.5.5.2]
576807  delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
115918675  delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial-like [KO:K00294] [EC:1.2.1.88]
576086  delta-1-pyrroline-5-carboxylate synthase [KO:K12657] [EC:2.7.2.11 1.2.1.41]
115924090  delta-1-pyrroline-5-carboxylate synthase-like isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
581093  cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
115924033  cytosol aminopeptidase-like [KO:K11142] [EC:3.4.11.1 3.4.11.5]
592929  prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
100892518  prolyl 4-hydroxylase subunit alpha-1 [KO:K00472] [EC:1.14.11.2]
100889761  uncharacterized protein LOC100889761 [KO:K00472] [EC:1.14.11.2]
115927869  transmembrane prolyl 4-hydroxylase-like [KO:K00472] [EC:1.14.11.2]
115918911  transmembrane prolyl 4-hydroxylase-like [KO:K00472] [EC:1.14.11.2]
576696  hydroxyproline dehydrogenase [KO:K11394] [EC:1.5.5.3]
589279  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
592180  aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
579934  4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
576222  LOW QUALITY PROTEIN: D-aspartate oxidase [KO:K00273] [EC:1.4.3.3]
590228  D-aspartate oxidase isoform X1 [KO:K00273] [EC:1.4.3.3]
585737  LOW QUALITY PROTEIN: trans-L-3-hydroxyproline dehydratase [KO:K18384] [EC:4.2.1.77]
582891  trans-L-3-hydroxyproline dehydratase [KO:K18384] [EC:4.2.1.77]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
spu00020  Citrate cycle (TCA cycle)
spu00220  Arginine biosynthesis
spu00250  Alanine, aspartate and glutamate metabolism
spu00260  Glycine, serine and threonine metabolism
spu00270  Cysteine and methionine metabolism
spu00310  Lysine degradation
spu00410  beta-Alanine metabolism
spu00470  D-Amino acid metabolism
spu00480  Glutathione metabolism
spu00630  Glyoxylate and dicarboxylate metabolism
spu00650  Butanoate metabolism
spu00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   
LinkDB

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