KEGG   PATHWAY: ssc00562
Entry
ssc00562                    Pathway                                
Name
Inositol phosphate metabolism - Sus scrofa (pig)
Class
Metabolism; Carbohydrate metabolism
Pathway map
ssc00562  Inositol phosphate metabolism
ssc00562

Module
ssc_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:ssc00562]
ssc_M00131  Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:ssc00562]
ssc_M00132  Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:ssc00562]
Other DBs
GO: 0006020
Organism
Sus scrofa (pig) [GN:ssc]
Gene
100144587  INPP5F; phosphatidylinositide phosphatase SAC2 isoform X1 [KO:K21798] [EC:3.1.3.-]
100152243  MINPP1; multiple inositol polyphosphate phosphatase 1 isoform X1 [KO:K03103] [EC:3.1.3.62 3.1.3.80]
100152339  ITPK1; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
100152497  PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116] [EC:3.1.4.11]
100152679  PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858] [EC:3.1.4.11]
100153301  ALDH6A1; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform X1 [KO:K00140] [EC:1.2.1.18 1.2.1.27]
100156264  PTEN; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
100156778  PI4KB; phosphatidylinositol 4-kinase beta isoform X1 [KO:K19801] [EC:2.7.1.67]
100156818  PI4K2A; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
100157143  PI4KA; phosphatidylinositol 4-kinase alpha isoform X1 [KO:K00888] [EC:2.7.1.67]
100157292  MTMR3; myotubularin-related protein 3 isoform X4 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
100157480  MTMR14; myotubularin-related protein 14 isoform X2 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
100157582  TPI1; triosephosphate isomerase [KO:K01803] [EC:5.3.1.1]
100157641  PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858] [EC:3.1.4.11]
100157745  PLCE1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
100233232  INPP4A; type I inositol 3,4-bisphosphate 4-phosphatase [KO:K01109] [EC:3.1.3.66]
100312963  CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
100462718  INPPL1; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 [KO:K15909] [EC:3.1.3.86]
100462756  INPP5K; inositol polyphosphate 5-phosphatase K [KO:K24222]
100510987  INPP5J; phosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform X2 [KO:K24222]
100511393  INPP4B; type II inositol 3,4-bisphosphate 4-phosphatase isoform X3 [KO:K01109] [EC:3.1.3.66]
100511669  FIG4; polyphosphoinositide phosphatase [KO:K22913] [EC:3.1.3.-]
100512110  INPP5B; LOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase [KO:K01099] [EC:3.1.3.36]
100512501  INPP5A; type I inositol 1,4,5-trisphosphate 5-phosphatase isoform X3 [KO:K01106] [EC:3.1.3.56]
100512551  PIK3C2B; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1 [KO:K00923] [EC:2.7.1.154]
100514555  MTMR8; myotubularin-related protein 8 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
100514626  PIK3C2A; LOW QUALITY PROTEIN: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
100514878  INPP1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
100516167  SYNJ2; LOW QUALITY PROTEIN: synaptojanin-2 [KO:K20279] [EC:3.1.3.36]
100516235  ITPKA; LOW QUALITY PROTEIN: inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
100516469  MTMR7; LOW QUALITY PROTEIN: myotubularin-related protein 7 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
100516581  PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
100516892  MTM1; myotubularin isoform X4 [KO:K01108] [EC:3.1.3.64 3.1.3.95]
100517258  MTMR1; LOW QUALITY PROTEIN: myotubularin-related protein 1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
100517493  MTMR4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
100518131  PIK3CD; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
100518140  MTMR2; myotubularin-related protein 2 isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
100518663  PLCG2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1 [KO:K05859] [EC:3.1.4.11]
100520306  PIP4K2C; phosphatidylinositol 5-phosphate 4-kinase type-2 gamma [KO:K00920] [EC:2.7.1.149]
100520446  PIP4K2A; phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [KO:K00920] [EC:2.7.1.149]
100521111  PLCD3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 isoform X1 [KO:K05857] [EC:3.1.4.11]
100521362  PIP5K1C; phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [KO:K00889] [EC:2.7.1.68]
100521692  PIKFYVE; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
100523714  PIP5KL1; phosphatidylinositol 4-phosphate 5-kinase-like protein 1 [KO:K13712] [EC:2.7.1.68]
100523844  PIK3C2G; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1 [KO:K00923] [EC:2.7.1.154]
100524376  ITPKC; inositol-trisphosphate 3-kinase C [KO:K00911] [EC:2.7.1.127]
100524726  OCRL; inositol polyphosphate 5-phosphatase OCRL-1 isoform X1 [KO:K01099] [EC:3.1.3.36]
100525148  PLCB3; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858] [EC:3.1.4.11]
100525664  SYNJ1; synaptojanin-1 isoform X1 [KO:K20279] [EC:3.1.3.36]
100526019  INPP5D; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1 [KO:K03084] [EC:3.1.3.86]
100621788  SACM1L; phosphatidylinositide phosphatase SAC1 isoform X1 [KO:K21797] [EC:3.1.3.-]
100621789  PIK3CA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [KO:K00922] [EC:2.7.1.153]
100622559  PIK3CB; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1 [KO:K00922] [EC:2.7.1.153]
100623031  PIP4K2B; phosphatidylinositol 5-phosphate 4-kinase type-2 beta [KO:K00920] [EC:2.7.1.149]
100623115  PI4K2B; phosphatidylinositol 4-kinase type 2-beta isoform X1 [KO:K13711] [EC:2.7.1.67]
100623323  IPMK; inositol polyphosphate multikinase isoform X1 [KO:K00915] [EC:2.7.1.140 2.7.1.151]
100623875  IMPA2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
100623940  PLCH2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 isoform X1 [KO:K19006] [EC:3.1.4.11]
100624272  PIP5K1A; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha [KO:K00889] [EC:2.7.1.68]
100627099  PLCD1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 [KO:K05857] [EC:3.1.4.11]
100627163  PLCH1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X3 [KO:K19006] [EC:3.1.4.11]
100739651  IPPK; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
102164283  ITPKB; LOW QUALITY PROTEIN: inositol-trisphosphate 3-kinase B [KO:K00911] [EC:2.7.1.127]
102167387  PIP5K1B; phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1 [KO:K00889] [EC:2.7.1.68]
110258074  INPP5E; 72 kDa inositol polyphosphate 5-phosphatase isoform X1 [KO:K20278] [EC:3.1.3.36]
396979  PIK3CG; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
397119  PLCD4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 [KO:K05857] [EC:3.1.4.11]
397189  MIOX; inositol oxygenase [KO:K00469] [EC:1.13.99.1]
397425  IMPA1; inositol monophosphatase 1 [KO:K01092] [EC:3.1.3.25]
397632  PLCZ1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 [KO:K05861] [EC:3.1.4.11]
503700  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 [KO:K00914] [EC:2.7.1.137]
Compound
C00024  Acetyl-CoA
C00092  D-Glucose 6-phosphate
C00111  Glycerone phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00137  myo-Inositol
C00191  D-Glucuronate
C00222  3-Oxopropanoate
C00558  D-Tagaturonate
C00641  1,2-Diacyl-sn-glycerol
C00691  2,4,6/3,5-Pentahydroxycyclohexanone
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C03659  D-Bornesitol
C03660  L-Bornesitol
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04287  3D-3,5/4-Trihydroxycyclohexane-1,2-dione
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04520  1D-myo-Inositol 3,4,5,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04563  D-myo-Inositol 1,2,4,5,6-pentakisphosphate
C04579  Inositol 1,2,3,5,6-pentakisphosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C06153  scyllo-Inositol
C06892  2-Deoxy-5-keto-D-gluconic acid
C06893  2-Deoxy-5-keto-D-gluconic acid 6-phosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C16737  5-Deoxy-D-glucuronate
C19794  CDP-1L-myo-inositol
C19799  Bis(1L-myo-inositol)-3,1'-phosphate 1-phosphate
C19891  1D-chiro-Inositol
C20251  1-Keto-D-chiro-inositol
C21643  3-Dehydro-scyllo-inosose
C21644  5-Dehydro-L-gluconate
Reference
PMID:14993306
  Authors
Yoshida K, Yamaguchi M, Ikeda H, Omae K, Tsurusaki K, Fujita Y
  Title
The fifth gene of the iol operon of Bacillus subtilis, iolE, encodes 2-keto-myo-inositol dehydratase.
  Journal
Microbiology 150:571-80 (2004)
DOI:10.1099/mic.0.26768-0
Reference
PMID:18310071
  Authors
Yoshida K, Yamaguchi M, Morinaga T, Kinehara M, Ikeuchi M, Ashida H, Fujita Y.
  Title
myo-Inositol catabolism in Bacillus subtilis.
  Journal
J Biol Chem 283:10415-24 (2008)
DOI:10.1074/jbc.M708043200
Related
pathway
ssc00010  Glycolysis / Gluconeogenesis
ssc00020  Citrate cycle (TCA cycle)
ssc00040  Pentose and glucuronate interconversions
ssc00564  Glycerophospholipid metabolism
KO pathway
ko00562   

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