KEGG   PATHWAY: sscv00564
Entry
sscv00564                   Pathway                                
Name
Glycerophospholipid metabolism - Syngnathus scovelli (Gulf pipefish)
Class
Metabolism; Lipid metabolism
Pathway map
sscv00564  Glycerophospholipid metabolism
sscv00564

Module
sscv_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:sscv00564]
sscv_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:sscv00564]
sscv_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:sscv00564]
Other DBs
GO: 0006650
Organism
Syngnathus scovelli (Gulf pipefish) [GN:sscv]
Gene
125965758  [KO:K14676] [EC:3.1.1.5]
125965796  pla2g1b; phospholipase A2 [KO:K01047] [EC:3.1.1.4]
125967343  lpin1a; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
125967354  lpcat2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
125968415  plpp2b; phospholipid phosphatase 2b [KO:K01080] [EC:3.1.3.4]
125968425  sgms2a; phosphatidylcholine:ceramide cholinephosphotransferase 2 [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
125968616  pcyt2; ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
125968754  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
125968783  [KO:K01080] [EC:3.1.3.4]
125968791  pnpla6; patatin-like phospholipase domain-containing protein 6 isoform X1 [KO:K14676] [EC:3.1.1.5]
125968865  pla2g4ab; cytosolic phospholipase A2 isoform X1 [KO:K16342] [EC:3.1.1.4]
125968947  pla2g6; 85/88 kDa calcium-independent phospholipase A2 isoform X1 [KO:K16343] [EC:3.1.1.4]
125969048  pla2g12a; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
125969511  [KO:K01047] [EC:3.1.1.4]
125970239  lcat; phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
125970240  pla2g15; lysosomal phospholipase A and acyltransferase [KO:K06129] [EC:3.1.1.5]
125970377  ptdss2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
125970443  chkb; choline/ethanolamine kinase isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
125970942  [KO:K00894] [EC:2.7.1.82]
125971140  chka; choline kinase alpha isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
125972137  plpp3; phospholipid phosphatase 3 isoform X1 [KO:K01080] [EC:3.1.3.4]
125972340  [KO:K00901] [EC:2.7.1.107]
125972609  pld3; 5'-3' exonuclease PLD3 [KO:K16860] [EC:3.1.4.4]
125973244  [KO:K00901] [EC:2.7.1.107]
125973251  pla1a; phospholipase A1 member A isoform X1 [KO:K13618] [EC:3.1.1.111]
125973331  agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
125973479  dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
125974780  ptdss1a; phosphatidylserine synthase 1 isoform X1 [KO:K08729] [EC:2.7.8.-]
125974812  dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
125974851  mboat7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
125975047  [KO:K13510] [EC:2.3.1.23 2.3.1.67]
125975107  mboat1; lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
125975139  gpd1l; glycerol-3-phosphate dehydrogenase 1-like protein isoform X1 [KO:K00006] [EC:1.1.1.8]
125975167  [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
125975726  lpcat3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
125977069  dgkab; diacylglycerol kinase, alpha b isoform X1 [KO:K00901] [EC:2.7.1.107]
125977193  [KO:K15728] [EC:3.1.3.4]
125977660  cept1b; choline/ethanolaminephosphotransferase 1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
125977728  etnk2; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
125977895  [KO:K00006] [EC:1.1.1.8]
125978124  crls1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
125978207  etnppl; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
125978309  [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
125978361  pla2g12b; group XIIB secretory phospholipase A2-like protein [KO:K01047] [EC:3.1.1.4]
125978391  [KO:K22697] [EC:2.7.8.48 3.1.4.62]
125978485  [KO:K16342] [EC:3.1.1.4]
125978728  plpp4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
125978757  agpat4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta isoform X1 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
125978832  chata; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
125979017  agpat5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
125979312  agpat2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform X2 [KO:K13509] [EC:2.3.1.51]
125979397  pisd; phosphatidylserine decarboxylase proenzyme, mitochondrial [KO:K01613] [EC:4.1.1.65]
125979547  [KO:K14676] [EC:3.1.1.5]
125979582  plpp1a; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
125979655  [KO:K01047] [EC:3.1.1.4]
125980866  lclat1; lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
125980962  pld1a; phospholipase D1a [KO:K01115] [EC:3.1.4.4]
125980979  plb1; phospholipase B1, membrane-associated isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
125981080  [KO:K01080] [EC:3.1.3.4]
125981298  mboat2a; lysophospholipid acyltransferase 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
125981330  pmt; phosphoethanolamine methyltransferase [KO:K05929] [EC:2.1.1.103]
125981431  [KO:K16860] [EC:3.1.4.4]
125981674  ache; acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
125981748  lpcat4; lysophospholipid acyltransferase LPCAT4 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
125981830  [KO:K00968] [EC:2.7.7.15]
125982596  pld2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
125983376  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
125983707  phospho1; probable phosphatase phospho1 isoform X1 [KO:K06124] [EC:3.1.3.75]
125983888  ppap2d; phosphatidic acid phosphatase type 2D [KO:K01080] [EC:3.1.3.4]
125984028  pla2g10; group 10 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
125984228  [KO:K00967] [EC:2.7.7.14]
125984418  lpin2; phosphatidate phosphatase LPIN2 [KO:K15728] [EC:3.1.3.4]
125984616  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
125985426  [KO:K01080] [EC:3.1.3.4]
125985486  pcyt1aa; choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
125985650  [KO:K06128] [EC:3.1.1.5]
125985718  [KO:K00968] [EC:2.7.7.15]
125986130  [KO:K15728] [EC:3.1.3.4]
125986310  [KO:K01115] [EC:3.1.4.4]
125986578  lypla2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
125986767  lpcat1; lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
125987576  [KO:K00901] [EC:2.7.1.107]
125987955  tafazzin; tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
125988269  gpd2; glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]
125988479  plaat1l; phospholipase A and acyltransferase 1 [KO:K16817] [EC:3.1.1.32 3.1.1.4]
125988532  [KO:K00006] [EC:1.1.1.8]
125988805  dgkaa; diacylglycerol kinase, alpha a [KO:K00901] [EC:2.7.1.107]
125989329  [KO:K00006] [EC:1.1.1.8]
125989434  [KO:K00901] [EC:2.7.1.107]
125989795  gpcpd1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]
125989956  lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
125990364  selenoi; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
125990395  gnpat; dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
125990407  lpin1b; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
125990415  [KO:K00649] [EC:2.3.1.42]
125990433  si:dkey-177p2.18; phospholipase B1, membrane-associated isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
125990671  [KO:K14621] [EC:3.1.1.4 3.1.1.5]
125990959  [KO:K00623] [EC:2.3.1.6]
125990984  [KO:K06124] [EC:3.1.3.75]
125991188  gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
125991374  [KO:K22697] [EC:2.7.8.48 3.1.4.62]
125991533  [KO:K00995] [EC:2.7.8.5]
125991608  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
125991688  pemt; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
125991935  dgki; diacylglycerol kinase iota isoform X2 [KO:K00901] [EC:2.7.1.107]
125991974  si:dkey-172j4.3; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
125992497  etnk1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
125992502  [KO:K00994] [EC:2.7.8.2]
125992503  [KO:K00994] [EC:2.7.8.2]
125992539  [KO:K01049] [EC:3.1.1.7]
125993490  pld7; 5'-3' exonuclease PLD3 isoform X4 [KO:K16860] [EC:3.1.4.4]
125993504  gpat2; glycerol-3-phosphate acyltransferase 2, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
125993738  [KO:K01080] [EC:3.1.3.4]
125993826  plpp5; phospholipid phosphatase 5 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
125993905  cds2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
125993933  gpat4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
125994082  cds1; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
125994089  agpat9l; glycerol-3-phosphate acyltransferase 3-like [KO:K13506] [EC:2.3.1.15]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
sscv00010  Glycolysis / Gluconeogenesis
sscv00260  Glycine, serine and threonine metabolism
sscv00561  Glycerolipid metabolism
sscv00562  Inositol phosphate metabolism
sscv00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
sscv00565  Ether lipid metabolism
sscv00620  Pyruvate metabolism
KO pathway
ko00564   

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