Target-based Classification of Drugs

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     Type
 G Protein-coupled receptors
 
 Ion channels
 
 Nuclear receptors
 
 Protein kinases
   Serine/threonine kinases
   Receptor serine/threonine kinases (RSTK)
   Receptor tyrosine kinases (RTK)
     EGFR family
       EGFR [HSA:1956] [KO:K04361]
         D03455  Cetuximab (USAN/INN) <JP/US>
         D05350  Panitumumab (USAN/INN) <JP/US>
         D10018  Necitumumab (USAN/INN) <JP/US>
         D07907  Erlotinib (INN)
         D08108  Lapatinib (INN)
         D04024  Lapatinib ditosylate (USAN) <JP/US>
         D06407  Vandetanib (JAN/USAN/INN) <JP/US>
         D09724  Afatinib (USAN/INN)
         D10858  Rociletinib (USAN/INN)
         D10859  Olmutinib (USAN/INN)
         D11115  Olmutinib hydrochloride (USAN)
         D08950  Neratinib (USAN/INN)
         D10898  Neratinib maleate <US>
         D09883  Dacomitinib (INN)
         D11251  Icotinib
         D04862  Masoprocol (USAN/INN)
         D03350  Canertinib dihydrochloride (USAN)
         D05399  Pelitinib (USAN/INN)
         D09660  Rindopepimut (USAN)
         D09689  Varlitinib (USAN/INN)
         D09690  Varlitinib tosylate (USAN)
         D10031  Zalutumumab (USAN/INN)
         D10439  Imgatuzumab (USAN/INN)
         D10886  Naquotinib mesylate (USAN)
         D10958  Naquotinib (USAN/INN)
         D11125  Modotuximab (USAN/INN)
         D11368  Mavelertinib (USAN/INN)
         D11410  Lifirafenib (USAN/INN)
         D11411  Lifirafenib maleate (USAN)
         D11430  Nazartinib (USAN/INN)
         D11434  Nazartinib mesylate (USAN)
         D11750  Duligotuzumab (USAN)
         D11772  Tesevatinib (USAN/INN)
         D11773  Tesevatinib tosylate (USAN)
         D11872  Serclutamab (USAN/INN)
         D11874  Serclutamab talirine (USAN/INN)
         D11894  Amivantamab (INN)
Monoclonal antibody
Monoclonal antibody
Monoclonal antibody
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Monoclonal antibody
Monoclonal antibody
 
 
Monoclonal antibody
 
 
 
 
 
Monoclonal antibody
 
 
 
 
Monoclonal antibody
       EGFR* [HSA_VAR:1956v2] [HSA:1956] [KO:K04361]
       EGFR* [HSA_VAR:1956v3] [HSA:1956] [KO:K04361]
       ERBB2 (HER2, CD340) [HSA:2064] [KO:K05083]
         D08108  Lapatinib (INN)
         D09724  Afatinib (USAN/INN)
         D09733  Afatinib dimaleate (USAN) <JP/US>
         D08950  Neratinib (USAN/INN)
         D09883  Dacomitinib (INN)
         D10514  Dacomitinib (USAN) <JP/US>
         D03350  Canertinib dihydrochloride (USAN)
         D04025  Mubritinib (USAN/INN)
         D06610  Lapuleucel-T (USAN)
         D09689  Varlitinib (USAN/INN)
         D09690  Varlitinib tosylate (USAN)
         D10344  Nelipepimut-S (USAN)
         D10446  Margetuximab (USAN)
         D11141  Tucatinib (USAN/INN) <US>
         D11375  Trastuzumab duocarmazine (USAN/INN)
         D11772  Tesevatinib (USAN/INN)
         D11773  Tesevatinib tosylate (USAN)
 
 
 
 
 
 
 
 
 
 
 
 
Monoclonal antibody
 
Antibody-drug conjugate
 
 
       ERBB2* (HER2, CD340) [HSA_VAR:2064v1] [HSA:2064] [KO:K05083]
       ERBB2* (HER2, CD340) [HSA_VAR:2064v1 2064v3] [HSA:2064] [KO:K05083]
       ERBB3 (HER3) [HSA:2065] [KO:K05084]
       ERBB4 (HER4) [HSA:2066] [KO:K05085]
         D09724  Afatinib (USAN/INN)
         D09733  Afatinib dimaleate (USAN) <JP/US>
         D08950  Neratinib (USAN/INN)
         D10898  Neratinib maleate <US>
         D09883  Dacomitinib (INN)
         D10514  Dacomitinib (USAN) <JP/US>
         D03350  Canertinib dihydrochloride (USAN)
         D09689  Varlitinib (USAN/INN)
         D09690  Varlitinib tosylate (USAN)
 
 
 
 
 
 
 
 
 
     INSR family
     PDGFR family
     FGFR family
     VEGFR family
     MET family
     TRK family
     EPH family
     AXL family
     ALK family
     TIE family
     RET family
     CCK family
   Non-receptor tyrosine kinases
 
 Cytokines and receptors
 
 Cell surface molecules and ligands
 
 Transporters
 
 Enzymes
 
 Nucleic acids
 
 Not elsewhere classified

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Last updated: November 20, 2020

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