Network variation - JAK-STAT signaling (cancer)
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ENTRY
nt06219
Name
JAK-STAT signaling (cancer)
Category
Disease view; Cancer signaling
Display
drug-target relation
disease type
N00053
Cytokine
→
Receptor
→
JAK
→
STAT
⇒
PIM1
N00181
vIL6
→
IL6ST
→
JAK2
→
STAT3
N00491
P12
→
IL2RB/G
→
JAK1/3
→
STAT5
⇒
IL2
N00094
EGF
→
EGFR
→
JAK1
→
STAT1/3/5
N00095
EGF
→
(
ERBB2*
+
EGFR
)
→
JAK1
→
STAT1/3
⇒
VEGFA
N00105
EML4-ALK
→
JAK3
→
STAT3,STAT5
N00055
BCR-ABL
→
STAT5
⇒
BCL2L1
N00219
FLT3LG
→
FLT3
→
STAT5
N00054
FLT3*
→
STAT5
⇒
PIM1/2
N01340
ACh
→
CHRNA7
→
JAK2
→
STAT3
N01341
(
NNK
,
NNN
)
→
CHRNA7
→
JAK2
→
STAT3
⇒
IKBKE
N01342
Nicotine
→
(
CHRNA4
+
CHRNB2
)
→
JAK2
→
STAT3
⇒
CCND1